Basic Information

Insect: Drosophila prostipennis
Gene Symbol: -
Assembly: GCA_037075205.1
Location: JBAMCJ010007674.1:558279-574228[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 3.9 3.1e+02 2.4 2.3 3 23 283 305 281 305 0.91

2 15 2 1.6e+02 3.3 1.6 3 21 447 465 445 469 0.90

3 15 0.045 3.6 8.5 0.2 2 23 491 513 490 513 0.92

4 15 2.4 1.9e+02 3.1 2.4 1 23 530 553 530 554 0.94

5 15 0.39 30 5.6 0.2 1 21 558 578 558 582 0.90

6 15 0.0022 0.17 12.6 0.5 2 23 626 648 625 648 0.92

7 15 0.085 6.7 7.6 0.3 3 21 655 673 653 674 0.91

8 15 3.4 2.7e+02 2.6 1.1 1 23 696 718 696 718 0.94

9 15 0.00026 0.021 15.5 2.3 2 23 731 751 730 751 0.97

10 15 2.1e-05 0.0017 19.0 2.6 1 23 757 780 757 780 0.98

11 15 0.00082 0.064 14.0 1.1 1 23 804 826 804 826 0.98

12 15 0.002 0.16 12.8 0.4 1 23 834 858 834 858 0.98

13 15 0.074 5.8 7.8 4.0 1 23 863 888 863 888 0.96

14 15 0.076 6 7.8 0.7 1 23 899 921 899 921 0.96

15 15 0.00084 0.066 13.9 4.8 1 21 927 947 927 952 0.93

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	3.9	3.1e+02	2.4	2.3	3	23	283	305	281	305	0.91
2	15	2	1.6e+02	3.3	1.6	3	21	447	465	445	469	0.90
3	15	0.045	3.6	8.5	0.2	2	23	491	513	490	513	0.92
4	15	2.4	1.9e+02	3.1	2.4	1	23	530	553	530	554	0.94
5	15	0.39	30	5.6	0.2	1	21	558	578	558	582	0.90
6	15	0.0022	0.17	12.6	0.5	2	23	626	648	625	648	0.92
7	15	0.085	6.7	7.6	0.3	3	21	655	673	653	674	0.91
8	15	3.4	2.7e+02	2.6	1.1	1	23	696	718	696	718	0.94
9	15	0.00026	0.021	15.5	2.3	2	23	731	751	730	751	0.97
10	15	2.1e-05	0.0017	19.0	2.6	1	23	757	780	757	780	0.98
11	15	0.00082	0.064	14.0	1.1	1	23	804	826	804	826	0.98
12	15	0.002	0.16	12.8	0.4	1	23	834	858	834	858	0.98
13	15	0.074	5.8	7.8	4.0	1	23	863	888	863	888	0.96
14	15	0.076	6	7.8	0.7	1	23	899	921	899	921	0.96
15	15	0.00084	0.066	13.9	4.8	1	21	927	947	927	952	0.93

Sequence Information

Coding Sequence: ATGGACACTGACGATCTAGAGGATACTCATCTGTGCATCAAGTGCAATGCCACGATACTTGGACTGACAAAGTACATCGAACACCGGAAACGGAACTGTCTCCTCACAGAGAAGCAAATCGTGACGCCAACTACTGAAGGACCAACCACCACCTCCACTCCCACCCAAGTATCGCCGACGATTATCAGTAGCAGCAACTTGGATCACACCTACGATGGCTTCCATTTCGCGGAACCGGAGGCTCCGAGCAGCTATCTCCGCAAGACGGCAGCCAGTCATGGAGGAAAGGCCTCCAAATCCTTGACGGAAGCCTATGACCTACCCTACGAACTTGGAGCTGATCTGTTCTTCTCCTCACTGCAACTGCAGAGCGTGTCGACGGGTGGGAAGACGGGATCTGTGGCTCGCCAGGAGCGAAGCAAGGATGAATCCTGGCCAGCACCCAGTGGCGATCCCTTGCTGAAAGCCGTTAGGGAGCACGATGAGACGGTGTTTAAGCCCCTGAACTTTGATCATGACTCCCCAGAGGGCAGTGAGGAAGAGGAGGATGACGAGGAGCACGATGACTTTGAGGATGATGAGGAGGAGTACGATGTGAGACGCCACTCGCCGCCCACTGTGCCCGCCACCCACACGGGTGGCAAGTGGAAGCCGGAACACCGACCGCAACTGCGACATCCGCACATAGAACGCCTCTCGCCCAGTTGGGATGAGCCCGGCGAGGAGAACTACACCCATCCCCCCGAGGATCATACGAAGGGCAAATGGGTGCCGGGCAGCAAACAGTTGGAGTATCGCGAAAACATAGATCTGACCAAGCTGGAGCAGCCGGGCGCTAGTTATTGGTGCAACATCTGCTGCAGGCGACTGAAGAGTCGCCTCAACTACGAGCAGCATTTGCGGAGTGGCTACCATGTGAAAAGAGCCGATGCCGAGTGCCACCTGGAGCAGGCCAGGCTGGGCAGTGAGCTCAACCTGAGCAAGGACTTTGTGGACTCAGTGGAGACCGGTGAGGAGAAGAAGCAGTCGAAGTCCCCGAAAAGACAGAGGAGAGCCAATCTGCTGCGATGCGATCTCTGCCGCCACACGATGGCCAGACATTTGATGGGCAAGCACTTGATTTCGCACTACCACTACCGAAGACTGCAGCAGCAGAGTCGAGTGAGAAGGCAGAGTTGCCTGCAGGAAATACTCAGCCACATGGGCAGCATAGTGAGGCAATCGCCCTTCCAGTGCCTGCCCTGCCGATTCTACGCCAACACGGAGGAGGCCTTTCTCCATCACTGGCAGTCGCAGGAGCACTCGGAACTCACGGAAAGTCTGGGGGGAGCCTTCTGGTGTGGCTACTGCCAGTTCGAGTGCAGCACCAATGCTTCGATGTGGCTGCACTTGCTGCATCCCTCGCACAAGGAGGTGCTCCTGGCCCTCAATAGATCGGTGCCCATATGCATAGCCCAAAGGAGACGCCTCGAGTGCCCCAGCTGTGGAGAGGGTTTCTTGTACAATTTCCAACTGCGTCGACACTTCGCCTCGGAACATCCTGGACTTGCGCCCGCAGGAACCGCAGCCGATGAATACCAGTGCCGGTTTCGATGTGGCCTGTGTGGAGCTCCGCAGAAGTCGCGATTGGCCCTGCAGCGCCACGAGAAGCACAAGCACCACGTGGCCAAGTACTACTGTGCCATCTGTCGATTGGAATTCGAGACGCCCTTGGAGGCGCGACGTCACCGCAGCTTAATGCAGCACAAACTTAGGGCCAGACCTAAAGTGATTGACACTTCCCAGCCGGAAAAGGAAATAGAACATATGCTGAGGGAGGTCCTGGAGGAGCCCACTCCGAACCCTCCCGCCAAAAGGAGTAGAGTTGTCAACTTGAAATGCTCGAATTGCCGGAAAATGTTCGACTCACCTCAGAGTTTGGCCGAACATCGAACTCAGGTCCATTCAGCCGACAATCATTTGTGCTTGAGCTGCGGCACCAGCTTTCAATCTGCCCAGGCCCTCGGCAGGCACACGAGGAGCTGCCAGCCCCTGGCCAGCACCTCATCCTCCGCCCATGAGTCCCTGGCCCAAGGGAAACCCTCCTACAGCTGCGATCAGTGTAGCTTCCAGTCTCAGTACGAGTCCGATCTGGTTTATCATCGCATTTTTCACACACGATCCGGAACGATTGGGAAAAACGAGCTGCTCCAGTGCCCCCTGTGTCCCAAGAACTTCAAGAAGCACTCCCTCAGAGCTCACCTTAGAAACCACACGGATGAGAAGATTTTCCAGTGCACAGAGTGCCTGCTGAAGTTCGCCCGGAGACACAACCTGAAGAATCACATGGCCACCATGCACGCGAAGAAGGAGGACCGGGAGAAGGCTAAATTGGCCCAGAAGAAGGCTGTCGATCTATCGAAACCCAAATATCAGTGCGGAACCTGCGGAAAAATACTGGCCAAAAAgcATTCCCTAAAACTACATGAGCTCAGTCACTCGAAGGAAGTGGAGCGGCGATATCGCTGCCATTTTGCAGACTGTTCGTATGCAGGTGTGACCCCGGAAAACCTTAAAAGCCACCTGATCTCCCACGCCCAGGGAACACACAAGTGTGAGCGGGACAACTGCAGCTATGTGGGAAAGAGTAAGCTGCATTTGAAAAGGCACCTCAAGTCGGCCCATTCCGCGAAGGAGGAGGGTGGTGCGGAGTGGTTCTCGTGCGATCAGTGCGAGTTCAGGGCCCGCATCAAGAGCCTCCTCCGCCGGCACTCGCTGGTCCACTCCGGCCAGAAGCCCCATCAGTGTCCCCACTGCGACTTTCAGTGCAGCACGACCGACAACCTCCGCAAGCACATCATCAAGACCGGCAAGCATCCCGGCAAGTTCATGTACGAGTGCACAAAGTGCTCCGACCAGGCGGCCAGCGAGTTCTTCCAGAGCAACAGCTTCAAGGACTTCCAGAAGCACTTGGAAACCCACAAAGCGGCCTGA
Protein Sequence: MDTDDLEDTHLCIKCNATILGLTKYIEHRKRNCLLTEKQIVTPTTEGPTTTSTPTQVSPTIISSSNLDHTYDGFHFAEPEAPSSYLRKTAASHGGKASKSLTEAYDLPYELGADLFFSSLQLQSVSTGGKTGSVARQERSKDESWPAPSGDPLLKAVREHDETVFKPLNFDHDSPEGSEEEEDDEEHDDFEDDEEEYDVRRHSPPTVPATHTGGKWKPEHRPQLRHPHIERLSPSWDEPGEENYTHPPEDHTKGKWVPGSKQLEYRENIDLTKLEQPGASYWCNICCRRLKSRLNYEQHLRSGYHVKRADAECHLEQARLGSELNLSKDFVDSVETGEEKKQSKSPKRQRRANLLRCDLCRHTMARHLMGKHLISHYHYRRLQQQSRVRRQSCLQEILSHMGSIVRQSPFQCLPCRFYANTEEAFLHHWQSQEHSELTESLGGAFWCGYCQFECSTNASMWLHLLHPSHKEVLLALNRSVPICIAQRRRLECPSCGEGFLYNFQLRRHFASEHPGLAPAGTAADEYQCRFRCGLCGAPQKSRLALQRHEKHKHHVAKYYCAICRLEFETPLEARRHRSLMQHKLRARPKVIDTSQPEKEIEHMLREVLEEPTPNPPAKRSRVVNLKCSNCRKMFDSPQSLAEHRTQVHSADNHLCLSCGTSFQSAQALGRHTRSCQPLASTSSSAHESLAQGKPSYSCDQCSFQSQYESDLVYHRIFHTRSGTIGKNELLQCPLCPKNFKKHSLRAHLRNHTDEKIFQCTECLLKFARRHNLKNHMATMHAKKEDREKAKLAQKKAVDLSKPKYQCGTCGKILAKKHSLKLHELSHSKEVERRYRCHFADCSYAGVTPENLKSHLISHAQGTHKCERDNCSYVGKSKLHLKRHLKSAHSAKEEGGAEWFSCDQCEFRARIKSLLRRHSLVHSGQKPHQCPHCDFQCSTTDNLRKHIIKTGKHPGKFMYECTKCSDQAASEFFQSNSFKDFQKHLETHKAA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00505709; iTF_00581871; iTF_00605202; iTF_00602960; iTF_00605914; iTF_00512350; iTF_00515864; iTF_00588505;
90% Identity: iTF_00605914;
80% Identity: -