Basic Information

Insect: Drosophila subpulchrella
Gene Symbol: -
Assembly: GCA_014743375.2
Location: NC:9846111-9862886[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 3.7 2.1e+02 2.4 2.3 3 23 285 307 283 307 0.91

2 16 3.7 2.1e+02 2.4 0.7 1 22 410 431 410 434 0.88

3 16 4.9 2.8e+02 2.0 1.4 3 21 447 465 446 469 0.90

4 16 0.025 1.4 9.2 1.1 2 23 491 513 490 513 0.93

5 16 2.3 1.3e+02 3.1 2.4 1 23 530 553 530 554 0.94

6 16 0.18 10 6.6 0.2 1 21 558 578 558 582 0.90

7 16 0.05 2.9 8.3 0.2 2 23 625 647 624 647 0.89

8 16 0.08 4.6 7.6 0.3 3 21 654 672 652 673 0.91

9 16 3.6 2.1e+02 2.4 0.9 1 23 695 717 695 717 0.93

10 16 0.00036 0.021 15.0 2.5 2 23 730 750 729 750 0.97

11 16 2.6e-05 0.0015 18.6 2.1 1 23 756 779 756 779 0.97

12 16 0.00076 0.044 14.0 0.5 1 23 803 825 803 825 0.97

13 16 0.006 0.35 11.2 0.7 1 23 833 857 833 857 0.98

14 16 0.16 9.2 6.7 3.1 1 23 862 887 862 887 0.96

15 16 0.18 10 6.5 2.6 1 23 898 920 898 920 0.97

16 16 0.001 0.06 13.6 4.1 1 21 926 946 926 951 0.93

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	3.7	2.1e+02	2.4	2.3	3	23	285	307	283	307	0.91
2	16	3.7	2.1e+02	2.4	0.7	1	22	410	431	410	434	0.88
3	16	4.9	2.8e+02	2.0	1.4	3	21	447	465	446	469	0.90
4	16	0.025	1.4	9.2	1.1	2	23	491	513	490	513	0.93
5	16	2.3	1.3e+02	3.1	2.4	1	23	530	553	530	554	0.94
6	16	0.18	10	6.6	0.2	1	21	558	578	558	582	0.90
7	16	0.05	2.9	8.3	0.2	2	23	625	647	624	647	0.89
8	16	0.08	4.6	7.6	0.3	3	21	654	672	652	673	0.91
9	16	3.6	2.1e+02	2.4	0.9	1	23	695	717	695	717	0.93
10	16	0.00036	0.021	15.0	2.5	2	23	730	750	729	750	0.97
11	16	2.6e-05	0.0015	18.6	2.1	1	23	756	779	756	779	0.97
12	16	0.00076	0.044	14.0	0.5	1	23	803	825	803	825	0.97
13	16	0.006	0.35	11.2	0.7	1	23	833	857	833	857	0.98
14	16	0.16	9.2	6.7	3.1	1	23	862	887	862	887	0.96
15	16	0.18	10	6.5	2.6	1	23	898	920	898	920	0.97
16	16	0.001	0.06	13.6	4.1	1	21	926	946	926	951	0.93

Sequence Information

Coding Sequence: ATGAACGCGGACGATCTGGAGGACACTCATTTGTGCATCAAGTGCAATGCCACGATACTAGGACTCGAGAAGTACATCGAGCACCGGAAACGGAACTGTCTTATGACTGAGAAACCAATTGTGACCCCTACAACAGATGGTCCACCAACCACCACCACTCCCACCCAAGTGTCCCCGACGATCATCAGTAGCAGTAACTTGGATCACACCTACGATGGCTTCCATTTCACGGAACCGGAGGCTCCTAGCAGCTATCTGCGCAAAACTGCAGCTAGCCATGGGGGAAAGGCCTCCAAATCCCTGACAGAAGCCTATGACCTACCCTATGAACTAGGAGCTGATCTGTTCTTTTCCTCACTGCAACTGCAGAGTGTTTCGACGGGTGGAAAAACGGGATCTGTGGCTCGCCAGGAGAGAAGCAAAGTGGAGTCCTGGCCAGCGCCCAGGGGCGATCCTTTGCTGAAAGCAGTAAGGGAACAGGATGAGGCGGTGTTCAAGCCCCTTAACTTTGATCATGACTCCCCAGAGGCCAgtgaggaggaggaggatgaggaggaACACGATGACTTTGATGCTGAGGAGGAAGATGAGGACTACGATGTGCGTCGTCACTCGCCGCCCACTGTGCCCGCCACCCACACAGGTGGCAAGTGGAAACCAGAGCACCGACCGCAGCTCAGGCATCCACATATAGAACGCGTCTCGCCCAGCTGGGATGAGCCGCCGGAGGAGACTTACACCCATCCCCCGGCCGATCATACAAAGGGCAAATGGGTTCCGGGTAGCAAACAGTTGGAGTACCGAGAAAACATAGATCTAACCAAACTGGAGCAACCGGGAGCCAGTTATTGGTGTAACATTTGCTGCCGGCGACTGAAGAGTCGCCTGAATTACGAGCAGCATTTGAGAAGTGGCTACCATGTGAAAAGAGCCGATGCGGAGTGTCATCTAGAGCAGGCTAACCTGGGCAGAGAACCCAGTCTGAGCAAGGATTTCGCAGTGGAAAAGAATGAGGACAAGAAGGAACCAAAGTCCTCCAAACGACAAAGAAGAGCCAATCTTTTGCGATGCGATCTCTGTCGGCACACAATGGCCAGACATTTGATGGGCAAGCATTTGATATCCCATTACCACTACAGAAGACTCCAGCAGCAGAATCGATTGAAGAAGCAATCTTGTCTGCAGGAAATACTCATCCACATGGGCAGCATAGTGAGGCAATCGCCTTTCCAGTGCCTGCCCtgcaaattttatttcaaCACGGAAGAAACATTTCTCCAACACTGGCAATCCGCAGAACACTTGGAGGTCACTAAAACACTAGGTGGAACCTTTTGGTGTGGCTATTGTCAGTATGAGTGCCAAACCAATGATACCATGTGGCTCCATTTGCTGCATCCCTCTCACAAAGAAGTGGTCTTGGCCCTCAACCGATCAGTTCCCATATGTATAGCCCAAAGAAGGGGACTTCAGTGCTCCAAGTGTGGAATGGGTTTCTTGTACAATTTCCAACTACGTAGGCACTTCAGCTCGGAACATCCTGGTCTTTCGCCTTCAGGAACCGCAGCCGATGAGTACCAGAGAAGGTTTCGATGTGGCTTGTGTGGTGCTCCTCAAAAATCCCGTTTGGCTCTGCAACGTCATGAAAAGCATAAGCACCATGTGGCCAAGTATTACTGTGACATCTGTCGACTGGAATTCGATTCACCTTTGGAGGCGCGACGTCATCGCAGCCTGATGCAACATAAACTAAATGCTAAACCTAAGAAGTTAATCACCCAGCCGGAAAAGGAAATAGAACACATGCTAAGGGAAGTCCTAGAGGAGGGCACTTCTAACCCACCCGCCAAAAAGGCTAAAGTTGTCAATTTAAAATGCTCAAATTGCCAAAAAATCTTTGACTCACCTCAGATTTTAGCCAAACATCGCGCTGAAGTTCATTCGGCGGATAATCATTTGTGTTTGAGCTGTGGAACCAGCTTTCAGTCTGCTCAGGCCTTGGGAAGGCACACAAGGAGCTGTCAGCCCCAAGCCAGCACTTCATCCTCCGCAAAACTATCTGTATCCCAAAGTAAACCCAACTACTCCTGTGATCAATGTAGCTTCAAGGCTCAGTACGAGTCCGATCTAGTTTATCATCGCATTTTCCACACACGATCCGAAACAATAGGAAAAAACGAGCTTCTTCGGTGCCCCTTGTGTCCCAAGAACTTTAAGAAGCACTCGCTGAGAGCTCATTTAAGAAACCACACAGATGAAAAGATTTTCGAGTGCACCGAGTGTCTTCTGAAATTTGCCAGAAGACACAATCTAAAGAACCACATGGCCACCATGCATGCCAAAAAGGAGGATCAGGAGAAGGCCGAAATGGTCAAGAAGAAATCTGAAGATCAACCGAAAGCCAAATTTCAATGTGGAACCTGTGGAAAAATACTGGCCAAAAAGTATTCCCTAAAACTACATGAGTCGAGTCACTCGAAGGAAGTGGAGCGGCGGTATCGCTGCCATTTTTCAGACTGTTCCTATGCAGGTGTGACCCCGGAAAGCCTCAAAACCCACCTGATCTCCCACGCCCAGGGGAGTCACAAGTGTGAGCGGGACAACTGCAGCTATGTGGGAAAGAGCGAGCTGCACCTGAAAAGGCACCTCAAGTCGGCCCATTCCGGTAAGGAGGAGGGCGGTGCGGAGTGGTTCTCGTGCGATCAGTGCGAGTTCAGGGCCCGCATCAAGGGCCACCTCCGCCGGCACTCGCTGCGCCACTCCGGACAGAAGCCCCACCAGTGTCCCCACTGCGACTTCCAGTGCAGCACGATCGACAACCTGCGCAAGCACATCATCAAGACGGGCAAGCATCCCGGCAAGTTCATCTACGAGTGCACCAAGTGCTCCGACCAGGCGGCCAGCGAGGTCTTCAAGAGCAACAGCTTCAAGGAGTTCCAGAAGCACTTGGAAACTCACAAAGCGaaaactcaaaactaa
Protein Sequence: MNADDLEDTHLCIKCNATILGLEKYIEHRKRNCLMTEKPIVTPTTDGPPTTTTPTQVSPTIISSSNLDHTYDGFHFTEPEAPSSYLRKTAASHGGKASKSLTEAYDLPYELGADLFFSSLQLQSVSTGGKTGSVARQERSKVESWPAPRGDPLLKAVREQDEAVFKPLNFDHDSPEASEEEEDEEEHDDFDAEEEDEDYDVRRHSPPTVPATHTGGKWKPEHRPQLRHPHIERVSPSWDEPPEETYTHPPADHTKGKWVPGSKQLEYRENIDLTKLEQPGASYWCNICCRRLKSRLNYEQHLRSGYHVKRADAECHLEQANLGREPSLSKDFAVEKNEDKKEPKSSKRQRRANLLRCDLCRHTMARHLMGKHLISHYHYRRLQQQNRLKKQSCLQEILIHMGSIVRQSPFQCLPCKFYFNTEETFLQHWQSAEHLEVTKTLGGTFWCGYCQYECQTNDTMWLHLLHPSHKEVVLALNRSVPICIAQRRGLQCSKCGMGFLYNFQLRRHFSSEHPGLSPSGTAADEYQRRFRCGLCGAPQKSRLALQRHEKHKHHVAKYYCDICRLEFDSPLEARRHRSLMQHKLNAKPKKLITQPEKEIEHMLREVLEEGTSNPPAKKAKVVNLKCSNCQKIFDSPQILAKHRAEVHSADNHLCLSCGTSFQSAQALGRHTRSCQPQASTSSSAKLSVSQSKPNYSCDQCSFKAQYESDLVYHRIFHTRSETIGKNELLRCPLCPKNFKKHSLRAHLRNHTDEKIFECTECLLKFARRHNLKNHMATMHAKKEDQEKAEMVKKKSEDQPKAKFQCGTCGKILAKKYSLKLHESSHSKEVERRYRCHFSDCSYAGVTPESLKTHLISHAQGSHKCERDNCSYVGKSELHLKRHLKSAHSGKEEGGAEWFSCDQCEFRARIKGHLRRHSLRHSGQKPHQCPHCDFQCSTIDNLRKHIIKTGKHPGKFIYECTKCSDQAASEVFKSNSFKEFQKHLETHKAKTQN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00578870;
90% Identity: iTF_00605202;
80% Identity: -