Basic Information

Insect: Drosophila pseudotakahashii
Gene Symbol: ZFAT
Assembly: GCA_035046095.1
Location: JAWNOE010000179.1:2943649-2958754[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 3.8 3.2e+02 2.4 2.3 3 23 285 307 283 307 0.91

2 14 1.6 1.4e+02 3.5 1.8 3 21 450 468 448 472 0.90

3 14 0.14 12 6.9 0.3 2 23 494 516 493 516 0.92

4 14 1.6 1.3e+02 3.6 2.3 1 23 533 556 533 557 0.94

5 14 0.38 32 5.6 0.2 1 21 561 581 561 585 0.90

6 14 0.0008 0.067 14.0 0.2 2 23 629 651 628 651 0.92

7 14 0.083 7 7.6 0.3 3 21 658 676 656 677 0.91

8 14 0.00018 0.016 16.0 2.4 2 23 734 754 733 754 0.97

9 14 2.9e-05 0.0024 18.5 2.0 1 23 760 783 760 783 0.97

10 14 0.0034 0.29 12.0 1.7 1 23 807 829 807 829 0.98

11 14 0.0069 0.58 11.0 1.1 1 23 837 861 837 861 0.97

12 14 0.072 6 7.8 4.0 1 23 866 891 866 891 0.96

13 14 0.074 6.3 7.8 0.7 1 23 902 924 902 924 0.96

14 14 0.00082 0.069 13.9 4.8 1 21 930 950 930 955 0.93

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	3.8	3.2e+02	2.4	2.3	3	23	285	307	283	307	0.91
2	14	1.6	1.4e+02	3.5	1.8	3	21	450	468	448	472	0.90
3	14	0.14	12	6.9	0.3	2	23	494	516	493	516	0.92
4	14	1.6	1.3e+02	3.6	2.3	1	23	533	556	533	557	0.94
5	14	0.38	32	5.6	0.2	1	21	561	581	561	585	0.90
6	14	0.0008	0.067	14.0	0.2	2	23	629	651	628	651	0.92
7	14	0.083	7	7.6	0.3	3	21	658	676	656	677	0.91
8	14	0.00018	0.016	16.0	2.4	2	23	734	754	733	754	0.97
9	14	2.9e-05	0.0024	18.5	2.0	1	23	760	783	760	783	0.97
10	14	0.0034	0.29	12.0	1.7	1	23	807	829	807	829	0.98
11	14	0.0069	0.58	11.0	1.1	1	23	837	861	837	861	0.97
12	14	0.072	6	7.8	4.0	1	23	866	891	866	891	0.96
13	14	0.074	6.3	7.8	0.7	1	23	902	924	902	924	0.96
14	14	0.00082	0.069	13.9	4.8	1	21	930	950	930	955	0.93

Sequence Information

Coding Sequence: ATGAACACTGACGATCTGGAGGATACTCATCTGTGCATCAAGTGCAATGCCACGATACTCGGACTCACAAAGTACATCGAGCACCGGAAACGGAACTGTCTCCTCACAGAGAAGAAAATTGTGACGCCGACAACAGAGGGACCAACCACCACCTCCACTCCCACCCAAGTATCGCCGACGATTATCAGTAGCAGCAACTTGGATCACACCTACGATGGCTTCCATTTCGCGGAACCGGAGGCTCCGAGCAGCTATCTTCGCAAGACGGCAGCGAGTCATGGAGGAAAGGCCTCCAAATCCTTGACTGAAGCCTATGACCTACCCTACGAACTTGGCGCTGATCTGTTCTTCTCCTCACTGCAACTGCAGAGCGTGTCGACGGGTGGGAAGACGGGATCTGTGCCTCGGCAGGAGCGAAGCAAGGATGAATCCTGGCCAGCACCCAGCGGCGATCCCTTGCTGAAAGCCGTTAGGGAACACGATGAGACGGTGTTTAAGCCCCTGAACTTTGATCACGACTCCCCTGAGGGCAGTGAGGAAGAGGAGGATGACGAGGAGCACGATGACTTCGAAGCCGACGATGATGAAGAGGAGTACGATGTGAGACGTCACTCGCCGCCCACTGTGCCCGCCACCCACACGGGTGGCAAGTGGAAACCGGAACACCGGCCGCAACTGCGACATCCGCATATAGAACGCCTCTCACCCAGTTGGGATGAGCCCGGCGAGGAGAACTACACCCATCCCCCCGAGGATCATACGAAGGGCAAATGGGTGCCGGGCAGCAAACAGTTGGAGTATCGCGAAAACATCGATCTGACCAAGCTGGAGCAGCCGGGCGCTAGTTATTGGTGCAACATCTGCTGCAGGCGACTGAAGAGTCGCCTCAACTACGAGCAGCATTTGCGTAGCGGCTACCATGTGAAAAGAGCCGATGCCGAGTGCCACCTGGAGCAGGCCACGCTGGGCAGTGAACTCAACCTGAGCAAGGACTTTGTGGACTCAGTGGAGACCGGtgaggagaagaagaaggaatCGAAGTCCCCAAAAAGACAGAGGAGAGCCAATCTGCTGCGGTGCGATCTCTGCCGCCATACGATGGGCCGGCATTTGATGGGCAAGCACTTGATTTCGCACTATCACTACCGAAGACTGCAGCAGCAGAGTCGGGTGAGAAGGCAGAGTTGCCTGCAGGAAATACTCAGCCACATGGGCAGCATAGTGAGGCAGTCGCCCTTTCAGTGCCTGCCCTGCAGATTCTATGCCAACACCGAGGAGGCCTTTCTCCATCACTGGCAGTCGCAGGAGCACTCGGAACTCACGGAAAGTCTGGGGGGAACCTTCTGGTGTGGCTACTGCCAGTTCGAGTGCAGCACCAATGTTTCGATGTGGCAGCACTTGCTGCATCCCTCGCACAAGGAAGTTCTCCTGGCCCTCAATAGATCGGTGCCCATATGCATAGCCCAAAGGAGACGGCTCGAGTGCCCCAGCTGTGGAGTGGGTTTCTTGTACAATTTCCAACTGCGTCGGCACTTCACCTCGGAGCACCCAGGACTCTCGCCCGCAGGAACTGCAGCCGATGAGTACCAGTGCCGGTATCGATGTGGCCTGTGTGGAGCTCCGCAGAAATCGCGCTTGGCTTTGCAGCGTCACGAGAAGCACAAGCACCACGTGGCCAAGTACTACTGTGCCATCTGTCGATTGGAGTTCGAGACGCCCTTGGAGGCGCGACGTCACCGCAGCTTGATGCAGCACAAACTTAAGGCCAGACCCAAAGTGATTGACACTTCCCAGCCGGAAAAGGAAATTGAACATATGCTGAGGGAGGTCCTGGAGGAGCCCACACCGAACCCTCCCGCCAAAAGGAGTAGGGTAGTCAACTTGAAATGCTCCAATTGCGAGAAAGTGTTCGACTCACCACAGAGTTTAGCCGAACATCGAACTCAGGTCCATTCAGCCGACAATCATTTGTGCTTGAGCTGCGGCACCAGCTTTCAATCTGCCCAAGCCCTCGGTAGGCACACGAGGAGCTGCCAGCCCCTGGCCAGCACCTCATCCTCCGCCAGTGAGTCCTTGGCCCAAGGGAAACCCTCCTACTGCTGCGATCAATGTAGCTTCCAGTCTCAGTACGAGTCCGATCTGGTTTATCATCGCATTTTTCACACACGAACCGGATCGATTGGGAAGAACGAGCTGCTCCAGTGCCCAATGTGTCCCAAGAACTTCAAGAAGCACTCCCTCAGAGCTCACCTAAGAAACCACACGGATGAGAAGATTTTCGAGTGCTCAGAGTGCCTGCTAAAGTTTGCTCGACGACACAACCTGAAGAATCACATGGCCACCATGCACGCGAAAACCGAGGGCCGGGAGAAGGCTAAGCTGGCCCAGAAGAAGGCTGGCGATCAATCGAAACCAAAGTATCAGTGCGGGACCTGCAATAAAATACTGGCTAAAAAGCATTCCCTAAAACTACATGAGCTCAGTCACTCGAAGGAAGTGGAGCGGCGACATCGCTGCCATTTTGCAGACTGTTCCTATGCAGGTGTGACCCCGGAAAACCTCAAAAGCCACCTGATCTCCCACGCCCAGGGAACACACAAGTGTGAGCGGGACAACTGCAGCTATGTGGGAAAGAGTAAGCTGCATTTGAAAAGGCACCTCAAGTCGGCCCATTCCGCGAAGGAGGAGGGTGGTGCGGAGTGGTTCTCGTGCGATCAGTGCGAGTTCAGGGCCCGCATCAAGAGCCTCCTCCGGCGGCACTCGCTGGTCCACTCCGGCCAGAAGCCCCACCAGTGTCCCCATTGCGACTTCCAGTGCAGCACGACCGACAACCTGCGCAAGCACATCATCAAGACGGGCAAGCATCCCGGCAAGTTTATGTACGAGTGCACAAAGTGCACCAGCGAGATCTTCCAGAGCAACAGCTTCAAGGAGTACCAGAAGCACTTGGAAACCCACAAAGCGGCCTGA
Protein Sequence: MNTDDLEDTHLCIKCNATILGLTKYIEHRKRNCLLTEKKIVTPTTEGPTTTSTPTQVSPTIISSSNLDHTYDGFHFAEPEAPSSYLRKTAASHGGKASKSLTEAYDLPYELGADLFFSSLQLQSVSTGGKTGSVPRQERSKDESWPAPSGDPLLKAVREHDETVFKPLNFDHDSPEGSEEEEDDEEHDDFEADDDEEEYDVRRHSPPTVPATHTGGKWKPEHRPQLRHPHIERLSPSWDEPGEENYTHPPEDHTKGKWVPGSKQLEYRENIDLTKLEQPGASYWCNICCRRLKSRLNYEQHLRSGYHVKRADAECHLEQATLGSELNLSKDFVDSVETGEEKKKESKSPKRQRRANLLRCDLCRHTMGRHLMGKHLISHYHYRRLQQQSRVRRQSCLQEILSHMGSIVRQSPFQCLPCRFYANTEEAFLHHWQSQEHSELTESLGGTFWCGYCQFECSTNVSMWQHLLHPSHKEVLLALNRSVPICIAQRRRLECPSCGVGFLYNFQLRRHFTSEHPGLSPAGTAADEYQCRYRCGLCGAPQKSRLALQRHEKHKHHVAKYYCAICRLEFETPLEARRHRSLMQHKLKARPKVIDTSQPEKEIEHMLREVLEEPTPNPPAKRSRVVNLKCSNCEKVFDSPQSLAEHRTQVHSADNHLCLSCGTSFQSAQALGRHTRSCQPLASTSSSASESLAQGKPSYCCDQCSFQSQYESDLVYHRIFHTRTGSIGKNELLQCPMCPKNFKKHSLRAHLRNHTDEKIFECSECLLKFARRHNLKNHMATMHAKTEGREKAKLAQKKAGDQSKPKYQCGTCNKILAKKHSLKLHELSHSKEVERRHRCHFADCSYAGVTPENLKSHLISHAQGTHKCERDNCSYVGKSKLHLKRHLKSAHSAKEEGGAEWFSCDQCEFRARIKSLLRRHSLVHSGQKPHQCPHCDFQCSTTDNLRKHIIKTGKHPGKFMYECTKCTSEIFQSNSFKEYQKHLETHKAA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00578870;
90% Identity: iTF_00605914;
80% Identity: -