Dpla010196.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila planitibia
Gene Symbol
-
Assembly
GCA_035043785.1
Location
JAWNMS010000062.1:1322436-1324480[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 10 0.12 7.7 7.1 0.3 1 21 317 337 317 338 0.95
2 10 3.4e-06 0.00021 21.4 1.8 1 23 346 368 346 368 0.99
3 10 0.00045 0.028 14.7 0.2 1 23 371 394 371 394 0.93
4 10 1.3e-06 8e-05 22.7 0.8 2 23 401 422 400 422 0.98
5 10 1.5e-07 9.1e-06 25.7 0.7 1 23 428 450 428 450 0.98
6 10 1.3e-05 0.00078 19.6 0.6 1 23 456 478 456 478 0.99
7 10 0.00096 0.059 13.7 3.7 1 23 484 506 484 506 0.99
8 10 0.001 0.064 13.6 0.3 1 23 512 534 512 534 0.98
9 10 0.00011 0.007 16.6 3.7 1 23 540 562 540 562 0.98
10 10 0.00023 0.015 15.6 0.2 1 23 568 590 568 590 0.97

Sequence Information

Coding Sequence
ATGGATGTGGAGAAGATTTGTCGCACTTGCCTAAGCCTCTCCGGCCCGTTCCTGTCCATCTACGATGGTGGCTCCGGCAGCTGCCTTGTAGATATGCTGCGCGAATTCACCAGGACACAACCGCGTCGCGAAGATAATTTGCCAGCGAGAGTTTGCCTGAGCTGCATCAGCGAAATCAATCACTGCTATTCGTTTAAGCTCAAGTGCGAGAGCTCGAATCGCACGCTACGCCAGCTGCTGCCCAATGCGCTGCCCGAGCAGACCGAATTCGTGGCCAAGCCAACAGTGCCCACATTTGAGAAATCCATGCAAACCAACGAAGTGCAAACAGCCACAGCAGAAGCGCAAACGGATGGGGTGACCACAACAGATGCGACACAAAACACCAGCCCGCAGCAGCCAGCGCCTGTGACCGTGCAGCCCCTGCAACAAAatgaggaagaggaggagcaggtggaggatgaggaggaagaggagcaAGAGGAGCAAGAATTTGACTATGAGTTTACAGAAGAACAGGAGGCCGATGATACGCCGTCCAAAGCAAGTGCTGAAAACATAATACTACACGTGGAGAAGGACAATGAGAAGTATGAAACGGAAATGGTGTACAACAAAACAACCGGGGAACTGCTGGAACAGAGTGTCGAGAACGTTGAGAAGCAGAAGGAATACAAATATCGACTAGtcagcaatggcaatggtgACACATTCATCTCCCCGGAGCCAGCGACCGCTGCAGCTCGCAAAGAGCTGATAACGCCTGATCAGCCGGAGACACGCGCAACGTCAAAGCGACGTcgagcggctgctgctgctactgttgcgcCACAGCTCAAGGAGCAGCCGGATGAGAGGCCGCCATCAGCCATGCCCGGcaagaaaccaaaaatcaacaacaacttcaatgAAACGCCTACAACTGAAATAGAGGAGCTAAAAGCGAATTTCCACTGCGATCGCTGCAATGCCGGCTTTGCTCTGGAGAAATCCCTCATCATTCACCGCAGGCAAAACGGCTGCACCCATCGCAACTTCAAGTGCAACGAATGCAAGCGCGTTTTCGTCTCGATGGATCATCTAACTGAGCATCAGGCGACGCATGGCACGTTCATGTGTCAGGAGTGCGGACTGCGCTTCGAGTCCATGGAGCAGCTGGGCAGGCACATGGTGCAGACGCACAAACGCAATCTGCGCAATCAGTGCAACGTTTGTCAGAAGGTCTTCACCATGCTGTCAACGCTGCGGGATCACATGCGCATCCACACCGGCGAGAAGCCGTTTGTGTGCAACGTGTGTGGCAAGGGTTTTACGCAGAATGCCAATTTGCGACAGCACAAGATGCGACACTCGGATATCAAGCGCTTCAAGTGTGAGCTGTGCAGCAATTCGTTTGTAACGAAAGCGGAGCTGACCTCGCATGCACGCACCCATACGGGCGTCAAGCCGTATCAGTGCGAGGTGTGCGCCTCCAGATTCACCACCAGCTGCTCCCTGGCCAAGCACAAGCGCAAGCATACCGGCGAGCGCCCGTATGCCTGTGATCTGTGTCCCATGCGATTTACGGCGCTGAACGTGCTGAAGAATCATCGGCGAACGCACACCGGCGAACGACCATTCGTTTGTCCGTTCTGCTCGAAGAGCTTCACGCAGCGCGGCGACTGCCAGATGCATCAGCGGACGCATCAGGGCGACAAGATCTACATTTGCCCCGTTTGCAATGAGGAGTTCAAAACGATGAACGATATGCGAACGCATCTCACGATACACGAGCAGGATGACAAGCGACTGGTGCATTTCACCCTGCTCAGCAACAAGGAGAATGGCAGTGGAACCCGGGAAGAGGCCGACGACGATTCGGATGCCACGCAGGATTTACTCTAG
Protein Sequence
MDVEKICRTCLSLSGPFLSIYDGGSGSCLVDMLREFTRTQPRREDNLPARVCLSCISEINHCYSFKLKCESSNRTLRQLLPNALPEQTEFVAKPTVPTFEKSMQTNEVQTATAEAQTDGVTTTDATQNTSPQQPAPVTVQPLQQNEEEEEQVEDEEEEEQEEQEFDYEFTEEQEADDTPSKASAENIILHVEKDNEKYETEMVYNKTTGELLEQSVENVEKQKEYKYRLVSNGNGDTFISPEPATAAARKELITPDQPETRATSKRRRAAAAATVAPQLKEQPDERPPSAMPGKKPKINNNFNETPTTEIEELKANFHCDRCNAGFALEKSLIIHRRQNGCTHRNFKCNECKRVFVSMDHLTEHQATHGTFMCQECGLRFESMEQLGRHMVQTHKRNLRNQCNVCQKVFTMLSTLRDHMRIHTGEKPFVCNVCGKGFTQNANLRQHKMRHSDIKRFKCELCSNSFVTKAELTSHARTHTGVKPYQCEVCASRFTTSCSLAKHKRKHTGERPYACDLCPMRFTALNVLKNHRRTHTGERPFVCPFCSKSFTQRGDCQMHQRTHQGDKIYICPVCNEEFKTMNDMRTHLTIHEQDDKRLVHFTLLSNKENGSGTREEADDDSDATQDLL