Basic Information

Insect: Drosophila engyochracea
Gene Symbol: -
Assembly: GCA_035042385.1
Location: JAWNLK010000101.1:10730779-10732762[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.12 7.5 7.1 0.3 1 21 301 321 301 322 0.95

2 10 1.7e-06 0.0001 22.4 1.5 1 23 330 352 330 352 0.99

3 10 0.0061 0.38 11.2 0.8 1 23 355 378 355 378 0.93

4 10 6.9e-07 4.4e-05 23.6 0.8 2 23 385 406 384 406 0.98

5 10 1.4e-07 8.9e-06 25.8 0.7 1 23 412 434 412 434 0.98

6 10 1.2e-05 0.00077 19.7 0.6 1 23 440 462 440 462 0.99

7 10 0.0004 0.025 14.9 4.6 1 23 468 490 468 490 0.99

8 10 0.00099 0.062 13.7 0.3 1 23 496 518 496 518 0.98

9 10 0.00011 0.0068 16.7 3.7 1 23 524 546 524 546 0.98

10 10 0.00023 0.014 15.7 0.2 1 23 552 574 552 574 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.12	7.5	7.1	0.3	1	21	301	321	301	322	0.95
2	10	1.7e-06	0.0001	22.4	1.5	1	23	330	352	330	352	0.99
3	10	0.0061	0.38	11.2	0.8	1	23	355	378	355	378	0.93
4	10	6.9e-07	4.4e-05	23.6	0.8	2	23	385	406	384	406	0.98
5	10	1.4e-07	8.9e-06	25.8	0.7	1	23	412	434	412	434	0.98
6	10	1.2e-05	0.00077	19.7	0.6	1	23	440	462	440	462	0.99
7	10	0.0004	0.025	14.9	4.6	1	23	468	490	468	490	0.99
8	10	0.00099	0.062	13.7	0.3	1	23	496	518	496	518	0.98
9	10	0.00011	0.0068	16.7	3.7	1	23	524	546	524	546	0.98
10	10	0.00023	0.014	15.7	0.2	1	23	552	574	552	574	0.97

Sequence Information

Coding Sequence: ATGGATGTGGAGAAGATTTGTCGCACTTGCCTAAGCCTCTCTGGCCCATTCCTGTCTATCTACGATGGTGGCTCCGGCAGCTGCCTGGTCGATATGCTGCGCGAATTCACCAGGACGCAACCGCGACGCGAAGATAATTTGCCAGCGAGAGTTTGCCTGAGCTGCATCAGCGAAATCAATCACTGCTATTCGTTTAAGCTCAAGTGCGAGAGCTCGAATCGCACGCTGCGCCAGCTGCTGCCCAATGCAATGCCCGAACAGCCCGAATTCGTGGCCAAGCCAACAGTGGCCACATCCGAGAAATCCATGCAAACCAACGAAGTGCAAACAGTCACAGCAGAAGCGCAAACGGATGGGGTGACCACAACAGATGCGACACAAAACACCAGCCTGCAGGAGCCAGCGCCTGTGACCGTGCAGCCCCAGCAACAAAatgaggaagaggaggagcaGGTGGAGGATGAGGacgaagaggaggaggaggagcaagaGTTTGACTATGAGTTTACAGAAGAACAGGAGGGCGATGAGGCGCCGTCCAAAACAAGTGCTGAAAACATAATACTACACGTGGAGAAGGACAATAAGAAGTATGAAACGGAAATGGTGTACAACAAAACAACCGGGGAACTGCGACTTGtcagcaatggcaatggcgatgCATTCATCTCCCCGGAGCCAGCGACCGCTGCAGCTCGCAAAGAGCTGATAACGTCTGATCAGCCGGAGACACGTGCAACGTCAAAGCGACGTcgagcggctgctgctgctgctactgttgcggCACAGCTCAAGGAGCAGCCGGATGAGAGGCCGCCATCAGCTATGCCCGGcaagaaaccaaaaatcaacaacttcAATGAAACGCCTGCAACTGAAATGGAGGAGCTAAAGGCAAATTTCCACTGCGATCGCTGCAATGCCGGCTTTGCTCTGGAGAAATCCCTCATCATTCACCGCAGGCAGAACGGTTGCACCCATCGAAACTTCAAGTGCAACGAGTGCAATCGCGTTTTCGTCTCGATGGATCATCTAACCGAGCATCAGGCGACGCATGGCACGTTCATGTGTCAGGAGTGCGGACTGCGCTGCGAGTCCATGGAGCAGCTGGGCAGGCACATGGTGCAGACGCACAAACGCAATCTGCGCAATCAGTGCAACATTTGTCAGAAGGTCTTCACCATGCTGTCGACGCTGCGGGATCACATGCGCATCCACACCGGCGAGAAGCCGTTTGTGTGCAACGTGTGTGGCAAGGGTTTTACGCAGAATGCCAATTTGCGGCAGCATAAGATGCGACACTCGGATATCAAGCGCTTCAAGTGTGAGCTGTGTAGCAATTCGTTTGTGACGAAAGCGGAGCTAACCTCGCATGCACGCACCCATACGGGCGTCAAGCCGTACCAGTGCGAGGTGTGCTCCTCCAGATTCACCACCAGCTGCTCCCTGGCCAAGCACAAGCGCAAGCATACCGGCGAGCGTCCGTATGCCTGTGATCTGTGCCCCATGCGATTTACGGCGCTGAACGTGCTGAAGAATCATCGACGAACGCACACCGGCGAACGACCATTCGTTTGTCCGTTCTGCTCGAAGAGCTTCACGCAGCGCGGCGACTGCCAGATGCATCAGCGGACGCATCAGGGCGACAAGATCTACATTTGCCCCGTTTGCAATGAGGAGTTCAAAACGATGAACGATATGCGAACGCATCTCACGATACACGAGCAGGATGACAAGCGACTGGTGCACTTCACCCTGCTCAGCAACAAGGAGAATGGCAGCGGAGCCCTGGAGGAGGCCGACGACGATTCGGATGCAACGCAGGATTTACTCTAG
Protein Sequence: MDVEKICRTCLSLSGPFLSIYDGGSGSCLVDMLREFTRTQPRREDNLPARVCLSCISEINHCYSFKLKCESSNRTLRQLLPNAMPEQPEFVAKPTVATSEKSMQTNEVQTVTAEAQTDGVTTTDATQNTSLQEPAPVTVQPQQQNEEEEEQVEDEDEEEEEEQEFDYEFTEEQEGDEAPSKTSAENIILHVEKDNKKYETEMVYNKTTGELRLVSNGNGDAFISPEPATAAARKELITSDQPETRATSKRRRAAAAAATVAAQLKEQPDERPPSAMPGKKPKINNFNETPATEMEELKANFHCDRCNAGFALEKSLIIHRRQNGCTHRNFKCNECNRVFVSMDHLTEHQATHGTFMCQECGLRCESMEQLGRHMVQTHKRNLRNQCNICQKVFTMLSTLRDHMRIHTGEKPFVCNVCGKGFTQNANLRQHKMRHSDIKRFKCELCSNSFVTKAELTSHARTHTGVKPYQCEVCSSRFTTSCSLAKHKRKHTGERPYACDLCPMRFTALNVLKNHRRTHTGERPFVCPFCSKSFTQRGDCQMHQRTHQGDKIYICPVCNEEFKTMNDMRTHLTIHEQDDKRLVHFTLLSNKENGSGALEEADDDSDATQDLL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00577199;
90% Identity: iTF_00521551;
80% Identity: -