Basic Information

Insect: Drosophila hawaiiensis
Gene Symbol: -
Assembly: GCA_037043685.1
Location: JBAMBA010000067.1:470957-472994[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.12 8.1 7.1 0.3 1 21 319 339 319 340 0.95

2 10 3.4e-06 0.00023 21.4 1.8 1 23 348 370 348 370 0.99

3 10 0.0062 0.41 11.1 0.8 1 23 373 396 373 396 0.93

4 10 7.1e-07 4.7e-05 23.5 0.8 2 23 403 424 402 424 0.98

5 10 1.5e-07 9.6e-06 25.7 0.7 1 23 430 452 430 452 0.98

6 10 1.2e-05 0.00083 19.6 0.6 1 23 458 480 458 480 0.99

7 10 0.00041 0.027 14.9 4.6 1 23 486 508 486 508 0.99

8 10 0.001 0.067 13.6 0.3 1 23 514 536 514 536 0.98

9 10 0.00011 0.0074 16.6 3.7 1 23 542 564 542 564 0.98

10 10 0.00023 0.015 15.6 0.2 1 23 570 592 570 592 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.12	8.1	7.1	0.3	1	21	319	339	319	340	0.95
2	10	3.4e-06	0.00023	21.4	1.8	1	23	348	370	348	370	0.99
3	10	0.0062	0.41	11.1	0.8	1	23	373	396	373	396	0.93
4	10	7.1e-07	4.7e-05	23.5	0.8	2	23	403	424	402	424	0.98
5	10	1.5e-07	9.6e-06	25.7	0.7	1	23	430	452	430	452	0.98
6	10	1.2e-05	0.00083	19.6	0.6	1	23	458	480	458	480	0.99
7	10	0.00041	0.027	14.9	4.6	1	23	486	508	486	508	0.99
8	10	0.001	0.067	13.6	0.3	1	23	514	536	514	536	0.98
9	10	0.00011	0.0074	16.6	3.7	1	23	542	564	542	564	0.98
10	10	0.00023	0.015	15.6	0.2	1	23	570	592	570	592	0.97

Sequence Information

Coding Sequence: ATGGATGTGGAGAAGATTTGTCGCACTTGCCTAAGCCTCTCCGGCCCATTCCTGTCTATCTACGATGGTGGCTCCGGCAGCTGCCTGGTCGACATGCTGCGCGAATTCACCAGAACGCAACCGCGTCGCGAAGATAATTTGCCAGCGAGAGTTTGCCTGAGCTGCATCAGCGAAATCAATCACTGCTATTCGTTTAAGCTCAAGTGCGAGAGTTCGAATCGCACCCTGCGCCAGCTGCTGCGCAATGCGCTGCCCGAGCAGCCCGAATTCGTGGCCAAGCCAACAGTGGCCACATCCGAGAAATCCATGCAAACCAACGAGGTGCAAACAGTCACAGCAGAAGCGCAAACGGATGGGGTGACCACAACAGATGCGACACAAAACACCAGCATGCAGGAGCCAGCGCCTGTGACCTTGCAGCCCCAGCAACAAAatgaggaagaggaggagcaggtggaggatgaggacgaagaggaggaggaggagcaggagttTGACTATGAGTTTACAGAAGAACAGGAGGGCGATGAGGCGCCGTCCAAAGCAAGTGCTGAAAACATAATACTACACGTGGAGAAGGACAATGAGAAGTATGAAACGGAAATGGTGTACAACAAAACAACCGGGGAACTGCTGGAACAGAGTGTCGAGAACGTTGACAAGCAGAAGGAATACAAATATCGACTTGtcagcaatggcaatggcgacACATTCATCTCCCCGGAGCCAGCGACCGCTGCAGCTCGCAAAGAGCTGATAACGTCCGATCAGCCGGAGACACGTGCAACGTCAAAGCGACGTcgagcggctgctgctgctgctgctactgttgcggCACAGCTCAAGGAGCAGCCGGATGAGAGACCGCCATCAGCTTTGCCCGGcaagaaaccaaaaatcaacaacaactttaatgAAACGCCTGCAACTGAAATGGAGGAGCTAAAAGCCAATTTCCACTGCGATCGCTGCAATGCCGGCTTTGCTCTGGAGAAATCCCTCATCATTCACCGCAGGCAAAACGGCTGCACCCATCGCAACTTCAAGTGCAACGAATGCAAGCGCGTTTTCGTCTCGATGGATCATCTAACCGAGCATCAGGCAACGCATGGCACGTTCATGTGTCAGGAGTGCGGACTGCGCTGCGAGTCCATGGAACAGCTGGGCAGGCACATGGTGCAGACGCACAAACGCAATCTGCGCAATCAGTGCAACATTTGTCAGAAGGTCTTCACCATGCTGTCAACGCTGCGGGATCACATGCGCATCCACACCGGCGAGAAGCCGTTTGTGTGCAACGTGTGTGGCAAGGGTTTTACGCAGAATGCCAATTTGCGGCAGCACAAGATGCGACACTCGGATATCAAGCGCTTCAAGTGTGAGCTGTGCAGCAATTCGTTTGTGACGAAAGCGGAGCTGACCTCGCATGCACGCACCCATACGGGCGTCAAGCCGTATCAGTGCGAGGTGTGCTCCTCCAGATTCACCACCAGCTGCTCCCTGGCCAAGCACAAGCGCAAGCATACCGGCGAGCGTCCGTATGCCTGCGATCTGTGCCCCATGCGATTTACGGCGCTGAACGTGCTGAAGAATCATCGACGTACGCACACCGGCGAACGACCATTCGTTTGTCCGTTCTGCTCGAAGAGCTTCACGCAGCGCGGCGACTGCCAGATGCATCAGCGGACGCATCAGGGCGACAAGATCTACATTTGCCCCGTTTGCAATGAGGAGTTCAAAACGATGAACGATATGCGAACGCATCTCACGATACACGAGCAGGATGACAAGCGACTGGTGCACTTCACCCTGCTCAGCAACAAGGAAAATGGCAGCGGAGCCCTGGAGGAGGCCGACGACGATTCGGATGCAACGCAGGATTTACTCTAG
Protein Sequence: MDVEKICRTCLSLSGPFLSIYDGGSGSCLVDMLREFTRTQPRREDNLPARVCLSCISEINHCYSFKLKCESSNRTLRQLLRNALPEQPEFVAKPTVATSEKSMQTNEVQTVTAEAQTDGVTTTDATQNTSMQEPAPVTLQPQQQNEEEEEQVEDEDEEEEEEQEFDYEFTEEQEGDEAPSKASAENIILHVEKDNEKYETEMVYNKTTGELLEQSVENVDKQKEYKYRLVSNGNGDTFISPEPATAAARKELITSDQPETRATSKRRRAAAAAAATVAAQLKEQPDERPPSALPGKKPKINNNFNETPATEMEELKANFHCDRCNAGFALEKSLIIHRRQNGCTHRNFKCNECKRVFVSMDHLTEHQATHGTFMCQECGLRCESMEQLGRHMVQTHKRNLRNQCNICQKVFTMLSTLRDHMRIHTGEKPFVCNVCGKGFTQNANLRQHKMRHSDIKRFKCELCSNSFVTKAELTSHARTHTGVKPYQCEVCSSRFTTSCSLAKHKRKHTGERPYACDLCPMRFTALNVLKNHRRTHTGERPFVCPFCSKSFTQRGDCQMHQRTHQGDKIYICPVCNEEFKTMNDMRTHLTIHEQDDKRLVHFTLLSNKENGSGALEEADDDSDATQDLL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00577199;
90% Identity: iTF_00521551;
80% Identity: -