Basic Information

Insect: Drosophila picticornis
Gene Symbol: -
Assembly: GCA_035043845.1
Location: JAWNMR010000492.1:19674497-19678860[-]

Transcription Factor Domain

TF Family: MBD
Domain: MBD domain
PFAM: PF01429
TF Group: Unclassified Structure
Description: The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 4.8e-14 8.7e-11 41.2 0.0 7 73 325 387 320 390 0.87

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	4.8e-14	8.7e-11	41.2	0.0	7	73	325	387	320	390	0.87

Sequence Information

Coding Sequence: ATGAATTCGACATCGCCAGACACATCTAGAGAAAGATCCAGTCGCTCAAAATCACGTTCAAGGAATATTTTTGAGGATACAAGCTCAAGCAGCGATTGTTATTCTTCAGGCTCAAATGACAGTCGCAAAAAGCTCCGGACCCGAAAGAGAGATGATGCTGTAGTAGGTTGGAGCGGCAATTTTCCAAACTTCTCGTCCACCCATATCCCGGAGAGCAACTCAAGCATGGAACAGCTGCCCACTGACCTAAAGGCCATTTTTGCCACTGGGCTAAGAATTTTTCCCagagaggaggaggaagaggaaaaatcgcagccgcagccagcACAGCAGACGCAGCTGTCGTCAACGCCGTCGTCTGAATCTGATTCCTCCTCGCCCGTTTCAAAAATGAATTCAGGtctaacaacagcagcagcattagacacaacaagcacaacagctAGTAGCACACGTACCACAAATTTGACTGCAACAAGTCCGAAGAGTGCTGCGCAGACAACCAACACCAACTGCGATATCAGCGATATCAATAACCTCAACGATATCAACAATATCAGCAATAACGACAGCGGTTCAACCTCAATGCCACGTGCAACATCTCCACAACCATCAGCGGAGCCAAAAACAGAATCAGAGCCACAAACCGATTTAGACATGCAGaAGGAGTCGATGCTGTTAAAGCTCCTACAAACCGGCAAACCCGATGCAGGCGAAGGAGAAAGAGGCAGCATCCAATTGGGCAAGCGCTCTCGCATGCGCTTTATGTCCTACAGTGCATCATCCAGCGATGAGGCCAGCGAAACGACAAAGCGCCCCAAAAAGACAATCGACGACAAGGATCATCCACCTTGCATGCTGCTGATGCGCTCCAAATCGATGTACCAATTTGACCCCACTAACAGTGATGCAAAGACACCCAAACGCCGTCGGTCGGTTGCTGCGAACAAACTGCTGGCCACAGATCCCTTCTATTGCGTGCCCTTCGAGCACGGCTGGAAGCGTGAATTGGTGTTGCGCAGCAATTTGAACAATGCGCGCCAGCGGGCCGACGTTATATTCATATCGCCGGGGGGCAAGAAGCTGCGCTCGAGAGATGAGATTGTCCCACTGCTTGCGCCCGATCTGTCCATTGATCATTTTTGCTTTAAGCCCCAACTTCAGAATGCTGGCGAGCATTATGAAACGGTCCGCCAGGGTCAGTCTGTTAAAGAACGTCGCAGATTGTTGGCCGTCgcaaagcagcagaaacagcaaggGCAAgggcaacagcatcagcagcagcagcagaaaccacaagggcagcagcagcaacagaagcaacaagagcagcagcagcagcagccgccgccacaacagcagcagcagatggcTAACAGTATCGATCTTGGCCAACAAGCAGCATCAACGCTAACACCCGTATTCGGGAAACGTGTGCCTAAGCCTAAGGTGCCCAAGGGCGCTAGCCCGCCGCCCGAGGGTTGGACCCCAACGATGGCGGTTAAGGGAAATGCACGCGTCCTGGCTGCGAGCAATGGTAACGGCAGTGGCGGCATCGGCTCCGGCGCCGGCAACAGCGCACGCAGGCGTGGCAGTAACCAGACGAACAAATCAACAAAGGCCGCACCAGAGACGACGACAGCGGTGCAGTCGAAGCTGCCGCTCCAGCCGCAGTCAGCCGTTGAGACGGTAATAACTTGTGCGAAATGCTTGCAGGCAATCAACCACCGCAATCAAGCCTTTCGTGTCGGGCTGAGCACTCACGAGAGCTACATCTGCAAGCGCTGTGTTATGCCTGGCAGCAAGTCTTCCCTTTCACCGCCAGCAGATATAGCacgacagcagcaggcacGCGGACATGAacatgccaatgccaatgctaGTGTCAATGCCAATGTCAATGGTAATGGGAACAATAAACTGGATAAGGAAGTGATCGATGAGAATGTGAACGCCGCCGGCAATGGGGTCACCGTCAAAGAGATTGAACTACCCGGCGCTCTGCCGCCTGCTAAGCTGCTCAGAGATGATTCTCCTGCACGTCGTGGCGGTAGAAAGATAACACCCAAGCCAATGGAGGTGGTTGTTATTAACGGTCGCAAGGCTGTCGCCATTGCTGTCTCGCCACCGCGTGCGCGTCCCCAAATACCACTCTTTACAGGCGATCCGAACGTTGATATGAATGTAAGATTTTTAGCTAGGCGCAACGCCACAGCCAAGGAGAAGCGTCGCCAAATCGTTGATTGTATTTCGGGTGGCAGCATGGGCTGCCAGCTGATGACGGCCATTATGAAGACGCTTGACCTGCACGAACGCGTGCGCTTGTCAAGTGTGTGCACGACCTGGGCTATGATAGGCCGCGATAGGAGCGTGTGGCGTACGGTGAAGTTGCGCGATACGCACATCAGCAACTGGATGCTTCTGCTGCGTGACATGGCGCGCTATCGCACCGCCGAGCTCGATATGATGGGCGTGAGAATCGACAATCCCAAGATGCGCTTGGACGGTGATTTGCGAGTGTTGAAATCGTTGCGCATCATACGCACCGATGCCAGCGAGGCGGAGTTCATCGAGACAATTGTGAAGCGCATGCCGCAACTGCTGGAGCTGCGCACAACGTGCACCAGTCGTGCTCTGAACCTAGCCAACATCGAAACGATGttggatttgtgtgtgctaCGCATTCGCATGCTGGAGCCGAAAGCCAGCATCACCTCATTGCCGCCGCTGCAGAAATTGAGCTGCTTGCGAGAGCTGAGCTTGCGCGGCATTAGCAACATGGCTCAGCTGgagctgttgcagctggagggattgcagcagctggagaCGCTTGTACTGGGTTCCTGTCGTGGCATGAAGGTGGCAACGTTCGGGCAACAAGTTCTGCCCAGTCTGAAGCGATTGCGCCACTTGCGCCTGGAGAACCACCACAGCAATCgctcatttaatataaaagagATCATGGAGGGCATTGCCGCCGCTGGCAGTGTAAAGCGTGTCGAACTCATCAATGTCAACGTAGATGCGGAGTTGAGTCGTCAGTTGTCCGAATGCAAATCGTTGCAAGAGCTGCTTCTGTTGCCAAATTTCCACAATCATACCGCCTATATGGTGCACTACATCATGCAGGCCATCAACGAGAACAGCGAACAGCTCAAAGTGTTCCGCCTGGGGATCACCTACGAACTGCTCAGCGTGACTCGGGCGTTGGCCATGATCCACGAGAAGGACTGTGTGCCAGTGCTGCTGCCCATTCCGGGCGTTCCCGAAAATGATGTACTGAATCAGTCCGATGAGCCAATCGCCTATTTGCCGGTAAATCGCCTCGAATCGATTTTACATCACATGATGCCGCAGGCTTGGCTAACTGTTGCCAAAGTTTCACAGCTTGAGACAATCAATCTGAAATTCCTGGCGGCTCCATCCACCGACAAAGGCGGGGTTGCAAACACTTAA
Protein Sequence: MNSTSPDTSRERSSRSKSRSRNIFEDTSSSSDCYSSGSNDSRKKLRTRKRDDAVVGWSGNFPNFSSTHIPESNSSMEQLPTDLKAIFATGLRIFPREEEEEEKSQPQPAQQTQLSSTPSSESDSSSPVSKMNSGLTTAAALDTTSTTASSTRTTNLTATSPKSAAQTTNTNCDISDINNLNDINNISNNDSGSTSMPRATSPQPSAEPKTESEPQTDLDMQKESMLLKLLQTGKPDAGEGERGSIQLGKRSRMRFMSYSASSSDEASETTKRPKKTIDDKDHPPCMLLMRSKSMYQFDPTNSDAKTPKRRRSVAANKLLATDPFYCVPFEHGWKRELVLRSNLNNARQRADVIFISPGGKKLRSRDEIVPLLAPDLSIDHFCFKPQLQNAGEHYETVRQGQSVKERRRLLAVAKQQKQQGQGQQHQQQQQKPQGQQQQQKQQEQQQQQPPPQQQQQMANSIDLGQQAASTLTPVFGKRVPKPKVPKGASPPPEGWTPTMAVKGNARVLAASNGNGSGGIGSGAGNSARRRGSNQTNKSTKAAPETTTAVQSKLPLQPQSAVETVITCAKCLQAINHRNQAFRVGLSTHESYICKRCVMPGSKSSLSPPADIARQQQARGHEHANANASVNANVNGNGNNKLDKEVIDENVNAAGNGVTVKEIELPGALPPAKLLRDDSPARRGGRKITPKPMEVVVINGRKAVAIAVSPPRARPQIPLFTGDPNVDMNVRFLARRNATAKEKRRQIVDCISGGSMGCQLMTAIMKTLDLHERVRLSSVCTTWAMIGRDRSVWRTVKLRDTHISNWMLLLRDMARYRTAELDMMGVRIDNPKMRLDGDLRVLKSLRIIRTDASEAEFIETIVKRMPQLLELRTTCTSRALNLANIETMLDLCVLRIRMLEPKASITSLPPLQKLSCLRELSLRGISNMAQLELLQLEGLQQLETLVLGSCRGMKVATFGQQVLPSLKRLRHLRLENHHSNRSFNIKEIMEGIAAAGSVKRVELINVNVDAELSRQLSECKSLQELLLLPNFHNHTAYMVHYIMQAINENSEQLKVFRLGITYELLSVTRALAMIHEKDCVPVLLPIPGVPENDVLNQSDEPIAYLPVNRLESILHHMMPQAWLTVAKVSQLETINLKFLAAPSTDKGGVANT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00513455;
90% Identity: iTF_00485853;
80% Identity: -