Basic Information

Insect: Drosophila basisetae
Gene Symbol: -
Assembly: GCA_035041595.1
Location: JAWNLB010000174.1:12273501-12277763[+]

Transcription Factor Domain

TF Family: MBD
Domain: MBD domain
PFAM: PF01429
TF Group: Unclassified Structure
Description: The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 8.8e-14 1.6e-10 40.3 0.0 7 73 319 381 314 384 0.87

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	8.8e-14	1.6e-10	40.3	0.0	7	73	319	381	314	384	0.87

Sequence Information

Coding Sequence: ATGAATTCGACATCGACAGACATATCTAGAGAAAGATCCAGCCGCTCAAAATCGCGCTCACGGAATATTTTTGAGGATACAAGCTCAAGCAGCGATTGTTATTCTTCAGGCTCAAATGACAGTCGCAGAAAGCTCAGGATCCGAAAGAGAGATGATGCTCTAGTAGGTTGGAGCGGCAATTTTCCGAATTTCTCGTCCACCCATAGCCTGGAGAGCAACTCGGACATGGAACAGCTGCCCACTGACCTAAAGGCCATTTGTGCTACTGGGCTAAGAATTTTTCCTAGAGAGCAAAAGGaagagcaacaattgcagacgcagacgcagctgTCGTCAACGCCGTCGTCCGAATCTGATTCCCCCTCACCCGtttcaaaaatgaattcagggctaacaacagcagcagcatcagccacaacaaacacaacagtTAGTAGCACACAGACCACAAATTTGAGTGTGACAAGTCTAAAGAGTGTTACGCAGACAACCAACACCAACTGCGATATCAGCAACATCGGCGATATCAACAATATCAGCAATAACGACAGCGGTTCAACCTCGATTCCAAGTGCAACATTTTCTCCGCAACCATCAGCAGACCCAAGAACAGAATTAGAGACACAAACCGATTTTGACAAGCAGaAGGAGGCGATGCTGTTAAATCTCCTGCAAACCGGCAAACCCGATGCAGGAGAAGGAGCAAGAGGCAGCATTTCGCTGATCAAGCGCCCCCTTATGCGCTTTATGTCCTATAGTGCATCATCCAGCGATGAGGCCAGCGAAACGACAAAGCGCCTCAAGAAACCAACCGACGACAAGGATCATCCACCCTGCATGCTGCAGATGCGCTCTAAATCGATGTACCAATTTGACCCCACTAGCAGTGACGCAAAGACGCCCAAACGCCGGCGCTCGGTTGCTGCAAACAAACTGCTGGCCACAGATCCCTTCTATTGCTTGCCTTTCGAGCACGGCTGGAAGCGTGAATTGGTGTTGCGCAGTAATCTGAACAATGCACGCCAGCAGGCCGACGTTATATTCATATCGCCGGGGGGCAAGAAGCTGCGCTCGAGAGATGACATTATCCCACTGCTTGTGCCCGATCTGTCAATTGatcatttttgctttaaacCCCAACTTCAGAATGCTGGCGAGCGTTATGAAACGGTCCGCCAGGGTCAGTCTGCTAAGGAACGTCGCAGATTATTGGCCGCCGCAAAGCATCAGAAACAGCAAGGGCaaggccaacagcagcaacagcaacagcaaaaaccacaaggacagcagcagccgaagcaacaagagcagcagcagccacaacaacaacagcagcagctggctaACAGTACTGATCTTGGCCAACAAGCAACATCAACGCTAACACCCGTATTCGGGAAACGTGTGCCTAAGCCTAAGGTGCCCAAGGGCGCTAGCCCCCCGCCCGAGGGTTGGACCCCCACGATGGCGGTTAAGGGAAATGCACGCGTTCTGGCTGCGAGCAATGGTAACAGCAGTGGCGGCATCGGCTCCAGCGCCGGCAACAGCGCACGCAGACGTGGCAGCAACCAGAcgaacaaatcaacaaaagcagcaccaGAGCCGACGACGGCGGTGCAGTCGAAGCTGTCGCTTCAGCCGCAGTCAGCCGTTGAGACGATAATAACTTGTGCGAAATGCTTGCAGGCAATCAATGACCGCAATCAAGCCTTTCGTGTCGGGCTGAGCACTATCGAGAGCTACATCTGCAAGCGCTGTGTTTTGCCTGGCAGCAAGGATTCTCTTTCGCCGCCAGCAGATATAGCccgacagcagcaggcacGTGGACCTGAacatgccaatgccaatgccaatgccaatgctaGTGTCAATGCCAATGTCAATGGTAATGGTGGAAACAAGAAGCTGGATAAGGAAGTGATCGATGAGAATGTGAACGCCGCCGGCAATGGGGTCATCGTCAAAGAGATTGAACTGCCCGGCGCTCTGCCGCCGGCTAAGCTACTCAGAGATGATTCTCCTGCACGTCGTGGTGGTAGAAAGATAACACCCAAGCCAATGGAGGTGGTTGTTATTAACGGTCGCAAGGCTGTCGCCGTTGCTGTCTCGCCACCGCGTACGCGTCCCCAAATACCACTCTTTTTAGGCGATCCGAACGTGGGTATCAATCTAAGATTTTTAGCTAGGCGCAACGCCACAGCTAAGGAGAAGCGTAACCAAGTCGTTGATTGCATTTCTGGTGGCAGCATGGGCTGCCAGCTGATGACGGCCATTATGAAGACGCTTGACCTGCACGAACGCGTGCGCTTGTCAAGTGTGTGCAAGACCTGGGCTATGATAGGCCGCGATAGGAGCGTGTGGCGTACGGTGAAGTTGCGCGATACGCACATCAGCAACTGGATGCTTCTGCTGCGTGACATGGCGCGCTATCGCACCGCCGAGCTCGATATGATGGGAGTGAGAATCGACTATCCAAAAATGCGCTTGGACGGTGACTTGCGAGTGTTGAAATCGTTGCGCATTCTACGCACCGATGCCAGCGAGGCGGAGTTTATCGAGACAATTGTGAAGCGCATGCCACAACTGTTGGAGCTGCGCACAACGTGCCTCAGTCGTGCTCTGAATCTGGCCAACATCGAAACGATGTtggatttgtgtgtgctgcgcATTCGCATGCTGGAGCCGAAAGCCAGCATCATCTCATTGCCGCCGCTGCAGAAATTGAGCTGCTTGCGAGAGCTGAGCTTGCGCGGCATTGGCAACATGGCTCAGCTggagctgttgcagctggagggattgcagcagctggagaCGCTTGTGCTAGGCTCCTGTCGCGGTATGAAGGTGGCAACGTTCGGGCAACAAGTTCTGCCCAGTCTGAAACGTTTGCGCCACTTGCGTCTGGAGAACCACCACAGCAATCgctcatttaatataaaagaGATAATGGATGGCATTGCCGCTGCTGGAACTGTGAAGCGTGTCGAACTCATCAATGTCAACGTAGATGCGGAGTTGAGTCGTCAGTTGTCCGAGTGTAAATCGTTGCAGGAGCTGCTTCTGTTGCCAAATTTCCACAATCATACCGCCTATATGGTGCACTACATCATGCAGGCGATCAACGAGAACAGTGAACAGCTCAATGTGTTCCGCCTGGGGATCACCTACGAACTTCTCAGCGTGACTCGGGCATTGGCCATGATCCACGAGAAGGACTGTGTGCCAGTGCTGCTGCCCATTCCGGGGGTCCCCGAAAATGATATACTGAATGAGTCCGATGAGCCAATCGCCTATTTGCCGGTCGATCGCCTCGAATCGATTTTACACCACATGATGCCACAGGCTTGGCTAACCGTTGCGAAGGTTTCACAGCTTGAGACAATCAATCTCAAATTCCTGGCGGCTCCATCCACCGACAAGGGCGGATTTTCAAACACTTAA
Protein Sequence: MNSTSTDISRERSSRSKSRSRNIFEDTSSSSDCYSSGSNDSRRKLRIRKRDDALVGWSGNFPNFSSTHSLESNSDMEQLPTDLKAICATGLRIFPREQKEEQQLQTQTQLSSTPSSESDSPSPVSKMNSGLTTAAASATTNTTVSSTQTTNLSVTSLKSVTQTTNTNCDISNIGDINNISNNDSGSTSIPSATFSPQPSADPRTELETQTDFDKQKEAMLLNLLQTGKPDAGEGARGSISLIKRPLMRFMSYSASSSDEASETTKRLKKPTDDKDHPPCMLQMRSKSMYQFDPTSSDAKTPKRRRSVAANKLLATDPFYCLPFEHGWKRELVLRSNLNNARQQADVIFISPGGKKLRSRDDIIPLLVPDLSIDHFCFKPQLQNAGERYETVRQGQSAKERRRLLAAAKHQKQQGQGQQQQQQQQKPQGQQQPKQQEQQQPQQQQQQLANSTDLGQQATSTLTPVFGKRVPKPKVPKGASPPPEGWTPTMAVKGNARVLAASNGNSSGGIGSSAGNSARRRGSNQTNKSTKAAPEPTTAVQSKLSLQPQSAVETIITCAKCLQAINDRNQAFRVGLSTIESYICKRCVLPGSKDSLSPPADIARQQQARGPEHANANANANASVNANVNGNGGNKKLDKEVIDENVNAAGNGVIVKEIELPGALPPAKLLRDDSPARRGGRKITPKPMEVVVINGRKAVAVAVSPPRTRPQIPLFLGDPNVGINLRFLARRNATAKEKRNQVVDCISGGSMGCQLMTAIMKTLDLHERVRLSSVCKTWAMIGRDRSVWRTVKLRDTHISNWMLLLRDMARYRTAELDMMGVRIDYPKMRLDGDLRVLKSLRILRTDASEAEFIETIVKRMPQLLELRTTCLSRALNLANIETMLDLCVLRIRMLEPKASIISLPPLQKLSCLRELSLRGIGNMAQLELLQLEGLQQLETLVLGSCRGMKVATFGQQVLPSLKRLRHLRLENHHSNRSFNIKEIMDGIAAAGTVKRVELINVNVDAELSRQLSECKSLQELLLLPNFHNHTAYMVHYIMQAINENSEQLNVFRLGITYELLSVTRALAMIHEKDCVPVLLPIPGVPENDILNESDEPIAYLPVDRLESILHHMMPQAWLTVAKVSQLETINLKFLAAPSTDKGGFSNT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00513455;
90% Identity: iTF_00498146; iTF_00595939; iTF_00518435; iTF_00501799; iTF_00570388; iTF_00576340; iTF_00557205; iTF_00542434; iTF_00499580; iTF_00577056;
80% Identity: -