Dobs000111.1
Basic Information
- Insect
- Drosophila obscura
- Gene Symbol
- lrrfip2
- Assembly
- GCA_018151105.1
- Location
- NW:3156702-3207291[+]
Transcription Factor Domain
- TF Family
- LRRFIP
- Domain
- LRRFIP domain
- PFAM
- PF09738
- TF Group
- Unclassified Structure
- Description
- LRRFIP1 is a transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'- AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA [1]. LRRFIP2 may function as activator of the canonical Wnt signalling pathway, in association with DVL3, upstream of CTNNB1/beta-catenin [2].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 2 6.2e-116 8.9e-112 372.9 22.9 1 299 30 321 30 322 0.98 2 2 0.034 4.9e+02 -0.5 3.6 210 241 341 371 323 395 0.52
Sequence Information
- Coding Sequence
- ATGGAAGGCACAAGCGCCACTGGTCGACGACGAAACAATACACGAGTGAATGCAGAGGACAACGCTTTAGATCAAATAACAAAAGAGGCCGAAGCGCGTCTTGCCGCACGTCGCCAAGCCCGTGCTGAAGCTCGCGAGATACGCATGAGAGAGCTTGAACGTCAACAAAAGGAACAGGAACAAAATGCTGACCGTGTATTCGATATGCAAAACTCAAGTGCCAGTTTTGGTAGTGACTCAATCTCATCACATCCTGCACGTCTCGTCTTTGGcggaatattaaatattactCGAACCACGACATCCCGACGCAGTAGTGAAGATTCTTTGGAGGATGAAGGCAGAAGCTTACGTGACTTCAAGTATGAGCTTAAAGATGTCGAAGAACGTTTCCGTAAAGCTATGATAACAAATGCACAGCTAGACAATGACCGTGCATCACAAACGTACGAAGTAAAATTGCTTAAGGACAAATGTGAAACCATTCATGAGGCATTTGCACAGCTACAGCGCGAGTTTAAAGAGAAGTCGCGTGACTGCAACGCTATTAAACGAAACTTAGACCGCACCACTCTTGAGCTTAAGCTAGTTCAAGGTCAGCTTAGCGAGCGAGATTCATTGATTGCAGAGCAGGGCCTTCTGATTGTTGCAATTGAAAATGCCGATGGCAGTGATGCCAAGCGAGCTCTAGTCAGTGTTGAAAACGCTAACGTGTTAGCGTCCGTTCAGGGTTCTTTAGATGtaagaatacaaaaattttgcGATGAAAAACAGCAATTACTATCTGAAGTGCAAAAGCTGCAGAAAATTATTAAAGAGTATAAAAGCGAAGGAATTGCTGTGCGTGACACTTTGTCACCGGGTCCCTTTGGTAAAGACAACGATTATGAGGCTCAAAGggaagcaaacaaaatcatATCAGACTGTAAATATAAGCTACAAAAGGCTGAACAAGAAATGGCTAATCTACAATCGAGCTTAGCACGTTCAGAGACGCAAGTTATTCGATACAAAAGTACCGCAGAAGCCGCCGAgaaggcagaagcagaatTAAAAGTGGAACGCCGTAAGCTTCAACGTGAGCACCGTGAAGTTTTGGAAAAACTGGAGGAAGCAGAGACAGCTAATAACCATTTATTGAAACGACttgacaaattaaaaaatgcgAAAAGTGCCATTCTTAAGGACCTATGA
- Protein Sequence
- MEGTSATGRRRNNTRVNAEDNALDQITKEAEARLAARRQARAEAREIRMRELERQQKEQEQNADRVFDMQNSSASFGSDSISSHPARLVFGGILNITRTTTSRRSSEDSLEDEGRSLRDFKYELKDVEERFRKAMITNAQLDNDRASQTYEVKLLKDKCETIHEAFAQLQREFKEKSRDCNAIKRNLDRTTLELKLVQGQLSERDSLIAEQGLLIVAIENADGSDAKRALVSVENANVLASVQGSLDVRIQKFCDEKQQLLSEVQKLQKIIKEYKSEGIAVRDTLSPGPFGKDNDYEAQREANKIISDCKYKLQKAEQEMANLQSSLARSETQVIRYKSTAEAAEKAEAELKVERRKLQREHREVLEKLEEAETANNHLLKRLDKLKNAKSAILKDL
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00336724;
- 90% Identity
- iTF_00514877;
- 80% Identity
- -