Basic Information

Insect: Drosophila nigricruria
Gene Symbol: Rfx2
Assembly: GCA_037075265.1
Location: JBAMCI010000160.1:4934911-4941265[-]

Transcription Factor Domain

TF Family: RFX
Domain: RFX domain
PFAM: PF02257
TF Group: Basic Domians group
Description: RFX is a regulatory factor which binds to the X box of MHC class II genes and is essential for their expression. The DNA-binding domain of RFX is the central domain of the protein and binds ssDNA as either a monomer or homodimer [1]. It recognize X-boxes (DNA of the sequence 5'-GTNRCC(0-3N)RGYAAC-3', where N is any nucleotide, R is a purine and Y is a pyrimidine) using a highly conserved 76-residue DNA-binding domain (DBD) [2].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 6.2e-38 6e-34 116.6 0.1 3 78 365 440 363 441 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	6.2e-38	6e-34	116.6	0.1	3	78	365	440	363	441	0.97

Sequence Information

Coding Sequence: ATGCATTCGCGATTCGGCTTCGACTGCCAGACGCgtcaccaacagcagcaacacctgcaccatcagcaacaccaacaccagcagcagcagcagcaacaacagcagcaacaacaacagcaacaacaccaccatcagcagcagctccaccatcagcatcatcatctgCCCGAATTGGATATCACGACACCACCGCCGATCACCGCCGCCGCCTATACGAATCTATTGGAGAAGTGTCGCTGCAAACTGCAATCACACTcccaacaccaccaccaccaccaatatcagcaactacaacaacagcaactgcagcagcagcagcagcagcaacagcagcagccactagCGCAACATCACCACCAGTTGCTGccgcagcaccagcaacagttgccagtGGCGGCGCCGCTGCCAGCcgcccagctgcagctgcaactgcaccaccatcaccatcatcatcaccatcagaCGTTCGTGGCCACCGCCAGCGCCGTCAACTACAGCAGCTGTACGGCAATaggtgccgccgccgccgccgctgccgcctcagcctcctcCTCCGCGACATCCAGCTCAACAGCAACTACTGCCATgtatcaccatcatcatcatcgacgCCACAACAACTTGTCCTATTGCGGTGTTTCCGGACAGGAACAAAACTATCAAGTGCAATATGTTGACTCGGAGCTGTACCACAGCAATTCCAGTCAGACCCAAATGACATATCCGTTCTGCCCGGTGGGCGATTATCAGAGCAATGGCCAGACGTATTACTCCACCACGGCAGCGACGGGCAATTATACGACCACGGCGGCGGGCAGCACAAGCAATGCACACTCGACGACGCTGCCGTACTTGGTGCCCGTGGACGATAGCCTCCTGTTGAATGGATCTTCGCAGTCGCACAGCCGGGACTCGCCGCACAGCCTGACGCATGAGGTCGCCTACATACAGGAGGCGCAGAGCACACCACAGACGCCCACCTCTACAACAACCACAAATTCGGCTAGCGGGGGCAGCATCGGCAACGGCGCCGATGGGGCGTCGCCCGACAGTGACCAGAGCGCAATGGGCACCAGCAATAAAATTGCCTCGGCAACGATTAAGTGGCTGTCGCGGAACTACGAGACGGCCGACGGAGTCAGTCTGCCACGGTCTACACTGTACAACCACTACATGCAGCACTGCAACGAACAGAAGCTGGAGCCAGTGAATGCAGCCAGCTTCGGCAAGCTAATACGCTCCGTGTTCTCCGGCCTGCGCACACGTCGCTTGGGCACTCGCGGCAACTCTAAGTACCATTATTATGGTATTCGCATCAAGCCAGGCTCGCTACTAATCCATCAATCCATGGAGGACAAATCTATGCAGGGATACGGCACTTCGCCGGGCAATGGCGCCATCGCCaatgtcagcagcagcaatgctaACCAGCTGGGCAGCTCCAACGGCAGCAACGGCATGTCCACATCTTCTGGCCAACGCACATCTGGTGCGAAGAAGCACAATTTCAAGCCGGAAACCTACGAGGCTTGCATACAGTATATTGGCGACGGTGCCGGCGCGATGCCCGTATTTCCGCCCATCGAACTGAGCCACAGCTTTCACAGTGAACTCACGCTGGACGATGTGGACACATTCCGTGCGCTGTACCGTGAGCACTGCGAATCTTTTTTGGATGCTGTACTCAACCTTGAGTTTGGCACTGTCGAATTTTTGCTACGCGATTTCTGGCGCACGTCGGACAACAACAATCTGGATGAGTGCGAAGAGGAAAAGTACTTGAGCAAGACAAAGCTGTATCTGTTGTGCCACTGCGCAGAAGTGCAAAAGTTTGTTCGCGAGGTGGACTATCAATTCTATCAGAATACAGTAGATGTTATAATACCGGATGTACTGCGCTCGATACCCAACGCGCTGACCCAGGCCATTCGCAACTTTGCCAAGAATCTGGAGTTATGGCTGTGTGAGAGCATGCTGGGCGTCCCGGAACAGCTGTCACAGATCAAGACTAGTGCCGTTTCGGCATTTTGCCAGACGCTGCGTCGCTACACTTCGCTGAATCATCTGGCACAAGCGGCACGTGCCGTGCTTCAGAATGGTGCGCAGATATCCCAAATGCTCAATGATTTGAATCGCGTAGACTTTCACAATGTACAGGAACAAGCCGCTTGGGTGAGTCAGTGTGCGCCAGCTGTGGTGCAGCGTCTGGAGAACGACTTTAAGGCAgcactgcagcagcaaagctCATTGGAGCAGTGGGCCAGTTGGTTGCAGCTGGTGGTGGAGTCGGCGATGGAGGAGTATACAGGGAAGCCGAGCTATGCACGTGCCGCTCGTCAGTTTCTGCTTAAGTGGAGCTTCTACAGCTCAATGATCATACGAGACTTGACACTGCGGTCCGCGTCAAGCTTCGGCAGCTTTCACCTGATACGACTGTTGTTCGACGAGTACATGTTCTATCTGGTGGAGCACAAAATAGCCGAGGCGCAACAGAAGACAGCCATTGCGGTTATTTGTGAGCGCATGAAGAAGGAAATGGACTTTGAGTTCGAGTGCCAGTTCGCCTACATAACTAGCGATGGGGAGCAACAGACAACGGCTAGCTCGGTCAGCGgtgCCCCAAGTGCAGGCAACGAAGCCAAGCGCCTGAAGCAGGAATGA
Protein Sequence: MHSRFGFDCQTRHQQQQHLHHQQHQHQQQQQQQQQQQQQQQHHHQQQLHHQHHHLPELDITTPPPITAAAYTNLLEKCRCKLQSHSQHHHHHQYQQLQQQQLQQQQQQQQQQPLAQHHHQLLPQHQQQLPVAAPLPAAQLQLQLHHHHHHHHHQTFVATASAVNYSSCTAIGAAAAAAAASASSSATSSSTATTAMYHHHHHRRHNNLSYCGVSGQEQNYQVQYVDSELYHSNSSQTQMTYPFCPVGDYQSNGQTYYSTTAATGNYTTTAAGSTSNAHSTTLPYLVPVDDSLLLNGSSQSHSRDSPHSLTHEVAYIQEAQSTPQTPTSTTTTNSASGGSIGNGADGASPDSDQSAMGTSNKIASATIKWLSRNYETADGVSLPRSTLYNHYMQHCNEQKLEPVNAASFGKLIRSVFSGLRTRRLGTRGNSKYHYYGIRIKPGSLLIHQSMEDKSMQGYGTSPGNGAIANVSSSNANQLGSSNGSNGMSTSSGQRTSGAKKHNFKPETYEACIQYIGDGAGAMPVFPPIELSHSFHSELTLDDVDTFRALYREHCESFLDAVLNLEFGTVEFLLRDFWRTSDNNNLDECEEEKYLSKTKLYLLCHCAEVQKFVREVDYQFYQNTVDVIIPDVLRSIPNALTQAIRNFAKNLELWLCESMLGVPEQLSQIKTSAVSAFCQTLRRYTSLNHLAQAARAVLQNGAQISQMLNDLNRVDFHNVQEQAAWVSQCAPAVVQRLENDFKAALQQQSSLEQWASWLQLVVESAMEEYTGKPSYARAARQFLLKWSFYSSMIIRDLTLRSASSFGSFHLIRLLFDEYMFYLVEHKIAEAQQKTAIAVICERMKKEMDFEFECQFAYITSDGEQQTTASSVSGAPSAGNEAKRLKQE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01355861;
90% Identity: iTF_00546395; iTF_00493387; iTF_00599323; iTF_00540107; iTF_00512461; iTF_00572341; iTF_00502262; iTF_00509560; iTF_00490525; iTF_00530694;
80% Identity: -