Dbuz004060.1
Basic Information
- Insect
- Drosophila buzzatii
- Gene Symbol
- Rfx2
- Assembly
- GCA_035045845.1
- Location
- JAWNOS010000139.1:19452-25073[-]
Transcription Factor Domain
- TF Family
- RFX
- Domain
- RFX domain
- PFAM
- PF02257
- TF Group
- Basic Domians group
- Description
- RFX is a regulatory factor which binds to the X box of MHC class II genes and is essential for their expression. The DNA-binding domain of RFX is the central domain of the protein and binds ssDNA as either a monomer or homodimer [1]. It recognize X-boxes (DNA of the sequence 5'-GTNRCC(0-3N)RGYAAC-3', where N is any nucleotide, R is a purine and Y is a pyrimidine) using a highly conserved 76-residue DNA-binding domain (DBD) [2].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 2 0.63 6.6e+03 -2.0 1.6 6 41 63 98 58 114 0.76 2 2 6.2e-38 6.5e-34 116.6 0.1 3 78 351 426 349 427 0.97
Sequence Information
- Coding Sequence
- ATGCATTCGCGATTCGGCTTCGACTGCCAGACGCGTCaccaacagcatcaacaacactTGCACCATCAGCcccaacaccagcagcagcagcagcagcagcaacagcaacaacaccaccatcagcagcatcatctTCTGCCAGAGTTGGACATAACGACACCACCGCCGATCAGCGCCGCCGCCTACACGAATCTATTGGAGAAGTGCCGCTGTAAGCTGCAATCCCAGTcccaacaccaccaccaccaccatcaatatcagcaacaacagcaacagcaccagcagcagcaacagcaacagacgcTAGCGCAACATCACCAccagttgctgccgcagcaccagcaacagttgccagtCGCGGCGACTCTACCAGCCGcccagctgcaactgcaactgcaccaccatcatcaccatcatcaccaccagaCGTTCGTGGCCACAGCCAGCGCCGTTAACTACAGCAGCTGCACGGCAATAGgtgccgccgccgtcgccgctgCAGCTTCCTCCTCCGCGACATCCagctcaacagcagcaagtgccatgtatcaccatcatcatcatcgacgCCACAACAACTTGTCCTATTGCGGtgTTTCCGGACAAGAACAAAATTATCAAGTGCAATATGTGGACTCGGAGCTGTACCACAGCAACTCTAGCCAGACCCAAATGACATATCCGTTCTGCCCGGTGGGCGATTACCAGAGCAATGGCCAGACGTACTACTCCACCACGGCAGCGACGGGCAACTATACGACCACGACTGCGGGCAGCACTAGCAATGCGCACTCGACGACCCTGCCGTATCTCGTGCCCGTGGACGATAGCCTCCTGTTGAATGGGTCCTCGCAGTCGCACAGCCGGGACTCACCGCACAGCCTGACGCATGAGGTTGCCTACATACAGGAGGCGCAGAGCACGCCACAGACACCCACCTCGACAACAACCACGAATTCTGCCAGCGGCGGCAGCATCGGCAACGGCGCCGAAGGGGCGTCGCCCGATAGTGACCAGAGCGCAATGGGCACCAGCAATAAAATCGCCTCGGCAACGATTAAGTGGCTGTCGCGCAACTACGAGACGGCCGACGGAGTCAGTCTGCCACGGTCCACGCTGTACAACCACTACATGCAGCACTGCAACGAGCAGAAGCTGGAGCCAGTGAATGCAGCCAGCTTTGGCAAACTAATACGGTCCGTGTTCTCTGGCCTGCGCACACGTCGCTTGGGCACTCGCGGCAATTCAAAGTACCACTATTATGGTATTCGCATCAAGCCCGGCTCACTATTAATCCATCAATCCATGGAGGACAAATCTATGCAGGGATATGGCTCATCGCCGGGGAACGGCACCATGAGTaatgtcagcagcagcaatgccaacCAGCTGGGCAACTCCAACGGCAGCAATGGTATGTCCACATCTTCGGGTCAGCGCACGGCTGGCACTAAGAAGCACACTTTCAAGCCGGAAACCTACGAGGCTTGTATACAGTATATTGGCGACGGTGCCGGCGCGATGCCCGTATTTCCGCCCATTGAACTAGGCCACAGCTTTCACAGTGAGCTTACGCTGGACGATGTGGACACATTCCGTGCGCTATATCGTGAGCACTGCGAATCATTTTTGGATGCAGTACTCAATCTCGAGTTTGGCACTGTTGAATTTTTGCTACGCGACTTCTGGCGCACCTCGGACAACAACAATCTGGACGAGTGCGAGGAGGAAAAATACTTGAGCAAGACGAAGCTGTATCTGTTGTGCCACTGCGCAGAAGTGCAAAAGTTTGTTCGCGAGGTGGACTACCAATTCTATCAGAATACTGTGGACGTTATAATACCAGATGTATTGCGCTCTATACCCAACGCGTTAACTCAGGCGATTCGCAACTTTGCCAAGAATCTGGAGTTGTGGCTTTGTGAAAGCATGTTGGGCGTACCGGAACAGCTGGCCCAGATCAAGACGAGTGCAGTTTCGGCATTTTGCCAGACGCTGCGGCGGTACACGTCGCTGAATCATCTGGCGCAGGCGGCACGCGCCGTGCTTCAGAATGGTGCACAGATATCCCAAATGCTCAATGATCTGAATCGCGTCGACTTTCACAATGTGCAGGAACAAGCCGCATGGGTGAGTCAGTGTGCACCGTCTGTGGTGCAGCGTTTGGAGAACGACTTTAAGGCAGccctgcagcagcagagctcTTTGGAGCAGTGGGCCAGCTGGCTGCAGCTGGTCGTCGAGTCCGCGATGGAGGAGTACACAGGGAAGCCGAGTTATGCACGTGCCGCTCGTCAGTTTCTGCTCAAGTGGAGCTTTTACAGCTCTATGATTATACGTGACTTGACACTGCGATCCGCGTCGAGCTTCGGCAGCTTTCACCTGATACGATTGTTGTTCGACGAGTACATGTTCTATCTAGTGGAGCACAAGATCGCCGAGGCGCAACAGAAGACGGCCATTGCGGTTATTTGTGAGCGCATGAAGAAGGAAATGGACTTTGAGTTCGAGTGCCAGTTCGCCTACATAACAAGCGATGCggagcagcaggcagcggCTAGCTCGGTCAGCGGTCCAGCAGTGGTGGCAGCAgtggcatcagcagcagcagccgctgcaggTGCCCCAAGTGCGGGCAACGAGGCCAAGCGCCTGAAGCAGGAATGA
- Protein Sequence
- MHSRFGFDCQTRHQQHQQHLHHQPQHQQQQQQQQQQQHHHQQHHLLPELDITTPPPISAAAYTNLLEKCRCKLQSQSQHHHHHHQYQQQQQQHQQQQQQQTLAQHHHQLLPQHQQQLPVAATLPAAQLQLQLHHHHHHHHHQTFVATASAVNYSSCTAIGAAAVAAAASSSATSSSTAASAMYHHHHHRRHNNLSYCGVSGQEQNYQVQYVDSELYHSNSSQTQMTYPFCPVGDYQSNGQTYYSTTAATGNYTTTTAGSTSNAHSTTLPYLVPVDDSLLLNGSSQSHSRDSPHSLTHEVAYIQEAQSTPQTPTSTTTTNSASGGSIGNGAEGASPDSDQSAMGTSNKIASATIKWLSRNYETADGVSLPRSTLYNHYMQHCNEQKLEPVNAASFGKLIRSVFSGLRTRRLGTRGNSKYHYYGIRIKPGSLLIHQSMEDKSMQGYGSSPGNGTMSNVSSSNANQLGNSNGSNGMSTSSGQRTAGTKKHTFKPETYEACIQYIGDGAGAMPVFPPIELGHSFHSELTLDDVDTFRALYREHCESFLDAVLNLEFGTVEFLLRDFWRTSDNNNLDECEEEKYLSKTKLYLLCHCAEVQKFVREVDYQFYQNTVDVIIPDVLRSIPNALTQAIRNFAKNLELWLCESMLGVPEQLAQIKTSAVSAFCQTLRRYTSLNHLAQAARAVLQNGAQISQMLNDLNRVDFHNVQEQAAWVSQCAPSVVQRLENDFKAALQQQSSLEQWASWLQLVVESAMEEYTGKPSYARAARQFLLKWSFYSSMIIRDLTLRSASSFGSFHLIRLLFDEYMFYLVEHKIAEAQQKTAIAVICERMKKEMDFEFECQFAYITSDAEQQAAASSVSGPAVVAAVASAAAAAAGAPSAGNEAKRLKQE
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00582009;
- 90% Identity
- iTF_00559233;
- 80% Identity
- -