Dful004840.1
Basic Information
- Insect
- Drosophila fulvimacula
- Gene Symbol
- Rfx2
- Assembly
- GCA_035045555.1
- Location
- JAWNOX010000137.1:3690950-3696575[-]
Transcription Factor Domain
- TF Family
- RFX
- Domain
- RFX domain
- PFAM
- PF02257
- TF Group
- Basic Domians group
- Description
- RFX is a regulatory factor which binds to the X box of MHC class II genes and is essential for their expression. The DNA-binding domain of RFX is the central domain of the protein and binds ssDNA as either a monomer or homodimer [1]. It recognize X-boxes (DNA of the sequence 5'-GTNRCC(0-3N)RGYAAC-3', where N is any nucleotide, R is a purine and Y is a pyrimidine) using a highly conserved 76-residue DNA-binding domain (DBD) [2].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 2 2 1.8e+04 -4.6 1.8 8 38 70 100 64 107 0.64 2 2 6.3e-38 5.7e-34 116.6 0.1 3 78 360 435 358 436 0.97
Sequence Information
- Coding Sequence
- ATGCATTCGCGATTCGGCTTCGACTGCCAGACGCgtcaccaacagcagcaacacctgcaccaccaccaacaccagcagcagcagcagcagcagcagcaacagcaacaacaccaccaacagcagcagcagctccaccaCCAGCATCATCACCTGCCCGAATTGGATATCACGACACCACCGCCGATCACCGCCGCCGCCTACACGAATCTATTGGAGAAGTGTCGCTGCAAACTGCAATCACAGTcccaacaccaccaccaccaccaccaatatcagcagcaacaacaccaccaccagcagcagcagcagcaacagcagcagccactagTGCAACATCACCACCAGTTGCTGccacagcaccagcaacagttgccagtGGCGGCCTCGCTGCCAGccgcccagctgcagctgcaactgcaccaccatcatcatcatcatcaccaccaGACGTTCGTGGCCACCGCCAGCGCCGTTAACTACAGCAGCTGTACGGCAATaggtgccgccgccgccgccgctgccgcctcaGCATCCTCCTCCGCGACAGCCAGCTCAACAGCAACTACTGCCATGtatcaccatcaccatcatcgACGTCACAACAACTTGTCCTATTGCGgtgTTTCCGGACAGGAGCAAAACTATCAAGTGCAATATGTGGACTCGGAGCTGTACCACAGCAATTCCAGCCAGACTCAAATGACATATCCGTTCTGCCCGGTGGGCGATTATCAGAGCAATGGCCAGACGTATTACTCAACCACGGCAGCGACGGGCAATTATACAACCACGACGGCGGGCAGCACAGGCAATGCACACTCGACGACGCTGCCGTACTTGGTGCCCGTGGACGATAGCCTCCTGTTGAATGGGTCGTCGCAGTCGCACAGCCGGGACTCACCGCACAGCTTGACGCACGAGGTTGCCTACATACAGGAAGCGCAGAGCACACCGCAGACGCCCACCTCTACGACAACCACAAACTCGGCCAGCGGAGGCAGCATCGGCAACGGGGCCGATGGGGCGTCGCCTGACAGTGACCAGAGCGCAATGGGTACCAGCAATAAAATTGCCTCGGCAACGATTAAGTGGCTGTCGCGGAACTATGAGACGGCCGACGGAGTCAGTCTGCCACGGTCCACTCTGTACAACCACTACATGCAGCACTGCAACGAGCAGAAGCTGGAGCCAGTGAATGCAGCCAGCTTCGGCAAGCTAATACGCTCTGTGTTCTCCGGCCTGCGTACACGTCGCTTGGGCACACGCGGCAACTCTAAGTATCATTATTATGGTATTCGCATCAAGCCAGGCTCGCTACTAATCCATCAATCCATGGAGGACAAATCTATGCAGGGATACGGCACATCGCCGGGCAATGGCGCCATCGCcaatgtcagcagcagcaatgctaACCAGCTGGGCAGCTccaatggcagcaacaacatgtcCACGTCTTCTGGCCAGCGCACAGCTGGTTCAAAGAAACACAATTTCAAGCCCGAAACCTACGAGGCTTGCATACAGTATATTGGCGACGGTGCCGGCGCGATGCCCGTGTTTCCGCCCATCGAGCTGAGCCACAGCTTTCACAGCGAACTCACGCTGGACGATGTGGACACATTCCGTGCGCTGTATCGTGAGCACTGCGAATCATTTTTGGATGCTGTACTCAACCTTGAGTTTGGCACTGTCGAATTTTTGCTACGCGATTTCTGGCGCACCTCGGACAACAACAATCTGGACGAGTGCGAAGAGGAAAAGTACTTGAGCAAGACGAAGCTGTATCTGTTGTGCCACTGCGCAGAAGTGCAAAAGTTTGTTCGCGAGGTGGACTATCAATTCTATCAGAACACCGTTGATGTTATAATACCGGATGTACTGCGCTCTATACCCAACGCACTGACTCAGGCTATTCGCAACTTTGCCAAGAATCTGGAGTTGTGGCTGTGTGAAAGCATGCTGGGCGTCCCGGAACAGCTGTCGCAGATCAAGACTAGTGCCGTTTCGGCATTTTGCCAGACATTGCGTCGCTACACGTCGCTGAATCATCTGGCACAGGCAGCACGCGCCGTGCTTCAGAATGGTGCACAAATATCCCAAATGCTCAATGATCTAAATCGCGTGGACTTTCACAATGTACAGGAACAAGCCGCTTGGGTGAGTCAGTGTGCACCAGCTGTGGTGCAGCGTCTGGAGAACGACTTTAAGgctgcactgcagcagcaaagctCATTGGAACAGTGGGCCAGTTGGCTGCAGCTGGTGGTCGAGTCCGCAATGGAAGAGTACACAGGGAAGCCGAGCTATGCACGTGCCGCTCGTCAGTTTCTGCTCAAGTGGAGCTTCTACAGCTCAATGATTATACGAGACTTGACACTGCGGTCCGCGTCGAGCTTCGGCAGCTTTCACCTGATACGGTTGCTGTTCGACGAGTACATGTTCTATCTGGTGGAGCACAAAATAGCCGAGGCGCAGCAGAAGACAGCCATTGCGGTTATATGTGAGCGCATGAAGAAGGAGATGGACTTTGAGTTCGAGTGCCAGTTCGCCTACATAACCAGCGATGGGGAGCAACAGACAGCGGCTAGCTCGGTCGGCGGTCCGGCGGTagtggcagcagtggcagcggcagctgctgcaggtgcCTCAAGTGCAGGCAACGAAGCCAAGCGCCTGAAGCAGGAATGA
- Protein Sequence
- MHSRFGFDCQTRHQQQQHLHHHQHQQQQQQQQQQQQHHQQQQQLHHQHHHLPELDITTPPPITAAAYTNLLEKCRCKLQSQSQHHHHHHQYQQQQHHHQQQQQQQQQPLVQHHHQLLPQHQQQLPVAASLPAAQLQLQLHHHHHHHHHQTFVATASAVNYSSCTAIGAAAAAAAASASSSATASSTATTAMYHHHHHRRHNNLSYCGVSGQEQNYQVQYVDSELYHSNSSQTQMTYPFCPVGDYQSNGQTYYSTTAATGNYTTTTAGSTGNAHSTTLPYLVPVDDSLLLNGSSQSHSRDSPHSLTHEVAYIQEAQSTPQTPTSTTTTNSASGGSIGNGADGASPDSDQSAMGTSNKIASATIKWLSRNYETADGVSLPRSTLYNHYMQHCNEQKLEPVNAASFGKLIRSVFSGLRTRRLGTRGNSKYHYYGIRIKPGSLLIHQSMEDKSMQGYGTSPGNGAIANVSSSNANQLGSSNGSNNMSTSSGQRTAGSKKHNFKPETYEACIQYIGDGAGAMPVFPPIELSHSFHSELTLDDVDTFRALYREHCESFLDAVLNLEFGTVEFLLRDFWRTSDNNNLDECEEEKYLSKTKLYLLCHCAEVQKFVREVDYQFYQNTVDVIIPDVLRSIPNALTQAIRNFAKNLELWLCESMLGVPEQLSQIKTSAVSAFCQTLRRYTSLNHLAQAARAVLQNGAQISQMLNDLNRVDFHNVQEQAAWVSQCAPAVVQRLENDFKAALQQQSSLEQWASWLQLVVESAMEEYTGKPSYARAARQFLLKWSFYSSMIIRDLTLRSASSFGSFHLIRLLFDEYMFYLVEHKIAEAQQKTAIAVICERMKKEMDFEFECQFAYITSDGEQQTAASSVGGPAVVAAVAAAAAAGASSAGNEAKRLKQE
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00582009;
- 90% Identity
- iTF_00559233;
- 80% Identity
- -