Basic Information

Insect: Drosophila mojavensis
Gene Symbol: -
Assembly: GCA_018153725.1
Location: JAECYD010000275.1:4126755-4131408[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 26 0.00028 0.022 15.2 1.4 1 23 220 242 220 242 0.97

2 26 0.04 3.1 8.4 2.0 1 23 248 270 248 270 0.97

3 26 0.39 30 5.3 1.0 2 20 302 320 302 323 0.94

4 26 0.016 1.3 9.7 1.6 1 23 400 423 400 423 0.93

5 26 7.4 5.8e+02 1.3 2.9 2 23 434 457 433 457 0.91

6 26 2.3 1.8e+02 2.9 0.3 1 20 463 482 463 484 0.88

7 26 0.29 23 5.7 1.4 2 23 500 521 499 521 0.97

8 26 0.43 33 5.2 5.3 1 23 601 623 601 624 0.94

9 26 0.0016 0.13 12.8 0.0 1 22 633 654 633 654 0.96

10 26 0.12 9 7.0 0.8 1 23 663 686 663 686 0.94

11 26 0.00095 0.074 13.6 0.2 2 23 718 739 717 739 0.97

12 26 8.6e-06 0.00067 20.0 3.1 1 23 747 769 747 769 0.99

13 26 0.034 2.6 8.7 0.9 1 23 917 940 917 940 0.92

14 26 0.0047 0.36 11.4 0.4 2 22 948 968 948 968 0.96

15 26 2.2 1.7e+02 3.0 0.4 1 23 977 1000 977 1000 0.85

16 26 1e-05 0.00078 19.8 2.4 1 23 1025 1047 1025 1047 0.98

17 26 0.00012 0.0097 16.3 0.9 1 23 1054 1076 1054 1076 0.98

18 26 0.024 1.8 9.2 0.0 2 21 1103 1122 1102 1123 0.94

19 26 0.01 0.78 10.4 4.1 1 23 1168 1191 1168 1191 0.96

20 26 0.0044 0.34 11.5 1.0 1 23 1228 1251 1228 1251 0.96

21 26 0.013 1 10.0 3.1 1 23 1279 1302 1279 1302 0.97

22 26 1.2e-05 0.00095 19.5 0.1 2 23 1330 1351 1329 1351 0.95

23 26 4.1e-05 0.0032 17.8 2.9 1 23 1357 1379 1357 1379 0.99

24 26 2e-06 0.00016 22.0 2.0 1 23 1385 1407 1385 1407 0.97

25 26 5.2e-08 4e-06 27.0 2.4 1 23 1413 1435 1413 1435 0.99

26 26 0.0001 0.0081 16.6 0.6 1 23 1441 1463 1441 1463 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	26	0.00028	0.022	15.2	1.4	1	23	220	242	220	242	0.97
2	26	0.04	3.1	8.4	2.0	1	23	248	270	248	270	0.97
3	26	0.39	30	5.3	1.0	2	20	302	320	302	323	0.94
4	26	0.016	1.3	9.7	1.6	1	23	400	423	400	423	0.93
5	26	7.4	5.8e+02	1.3	2.9	2	23	434	457	433	457	0.91
6	26	2.3	1.8e+02	2.9	0.3	1	20	463	482	463	484	0.88
7	26	0.29	23	5.7	1.4	2	23	500	521	499	521	0.97
8	26	0.43	33	5.2	5.3	1	23	601	623	601	624	0.94
9	26	0.0016	0.13	12.8	0.0	1	22	633	654	633	654	0.96
10	26	0.12	9	7.0	0.8	1	23	663	686	663	686	0.94
11	26	0.00095	0.074	13.6	0.2	2	23	718	739	717	739	0.97
12	26	8.6e-06	0.00067	20.0	3.1	1	23	747	769	747	769	0.99
13	26	0.034	2.6	8.7	0.9	1	23	917	940	917	940	0.92
14	26	0.0047	0.36	11.4	0.4	2	22	948	968	948	968	0.96
15	26	2.2	1.7e+02	3.0	0.4	1	23	977	1000	977	1000	0.85
16	26	1e-05	0.00078	19.8	2.4	1	23	1025	1047	1025	1047	0.98
17	26	0.00012	0.0097	16.3	0.9	1	23	1054	1076	1054	1076	0.98
18	26	0.024	1.8	9.2	0.0	2	21	1103	1122	1102	1123	0.94
19	26	0.01	0.78	10.4	4.1	1	23	1168	1191	1168	1191	0.96
20	26	0.0044	0.34	11.5	1.0	1	23	1228	1251	1228	1251	0.96
21	26	0.013	1	10.0	3.1	1	23	1279	1302	1279	1302	0.97
22	26	1.2e-05	0.00095	19.5	0.1	2	23	1330	1351	1329	1351	0.95
23	26	4.1e-05	0.0032	17.8	2.9	1	23	1357	1379	1357	1379	0.99
24	26	2e-06	0.00016	22.0	2.0	1	23	1385	1407	1385	1407	0.97
25	26	5.2e-08	4e-06	27.0	2.4	1	23	1413	1435	1413	1435	0.99
26	26	0.0001	0.0081	16.6	0.6	1	23	1441	1463	1441	1463	0.98

Sequence Information

Coding Sequence: ATGTTACCGACAGATATTTGTCGTACATGCACATTGCATGATGATTGCTTGTTTCCGCTTACGACCCGCACAGATAAATATGAAAATAAAAGTTTAAATGAAATGTTACTTGAATTGACACAAAATGATCCCCTGCTGGAGCATACAGATGACAGTCTGCCGCAGCACTTGTGTAGTGGCTGCTTGCACAAGTTGGAGGCTGCGTACGCGTTTGTATTGCAAGCGCGCCACGCTCAAGAGCAATTGTTGTTGCAGCTGCGCAAAAGCTTGCAGCCACAGTGCTTGGATGAGATGCCCATAGACATTAACTTGCAGCACATAAAAACTGAGATGATCGTTGACATGCAACCTGCTAGCAAAGCGAAGAGTGAAGAAGATGAGGCGGAGGCTGAAGAGAGGGAGCAAGATATGGCTGTAGTGGCAATTCCTGCCCTGAAATGGCAGCCAAACAGCGACAGTGAGAGCAATCAGACTGCTGCTCATGAGCAGGATATAGACTTTAAGCCCAAGCAGTTGCGGCGCAGCGCACGTAAAGCCAAAACCTACACAGATAGCGAAAATGAAGCAACATCTACCGATGCGACTTCCTTGCCCATCAAACGGCGACGTGGTCGTCCAGCACGTGTTAACACGGAGGCGATTAACGAAGAAGGACGGCATGTGTGCGAGGTTTGTGGAAAGAGCTTCTCCTGGTACCGCGACATGCAGCGCCACACGCGCATTCACTTCGAGCAACCGACCTTCGTGTGTGACAGTTGTGGCAAGAGCTTCTTGCGCAAAGACAAATACATGTTTCATCTGCGTTCGCACGAAAAGCGAGCAGCCAAGTGTCAGGCCACGCAATTGAGCACCGAGTGGTGTTTTGCTGAACGTCTCTACAACTCCGGCCGACTCAAACAGGCGGAGTGCAAATTGTGCGGCTCGAAATACCAGCGTATAGGGGAGCTGCGCGAGCATATGGCGTGCCATAAGAGCATTGAGACTTTGTCGAAGCTGAGTCTGGAGAGCGACGTTATCAGAAAACATTTTGCTAAAGAGCAGCAGCAGGTCGACTTGGAACTGATCAAACAACATATATGTGCTGACATTGACAGAGGACGTGAGCACCTGGACAAATACTGCGCTGTGGTCAACGCGTACGGATATGAGCTCTGTCTTAGCGACTCAGACGAAGAAGCAGCTGACCAATCGCCTAAATACAAGTGTCGTCCATGCAACATCAACTTCACGCGTAAATATCGCCTTATGCGCCACACACTGGAGGAGCACACACAGACGGAACCAGCAGTGTATTGGCAACGCTGTGATGTTTGCCAAATTGGTTTTGTGTGTACTATAATGTTGGAGCAACATCAACGCACGCAGTGCCACAACAAACTTAAGCGTTACAGTTGTCCCAACTGCCCAGGTAAATTTATTTGGCAGCAGAACCTGGACCAGCATGCGTGCTCGCAACGTAGCAATCAGCTCGACGAGCAACGGCAACGGCAGCAAAAGCAGTGTTGTCTCTGTGATATCCAATTGAACACCATGTTCGAATTACGCGCCCATTTGCTTAGCCATCAAGATGGACGCAGTGGGATACATCCGGAGCAGCAGGCGACCTTCTTTCGTACCTACTATCCCAATGGCCTTGACTGCAGCTTGTCGGAGCTGAGCGCACGGATTGCCGCCGACTTTAAGGCTGAGGATTATGGGCGATACTTTAATGCCAACACGAAAAACGGCGAGGAGCTCGATTTCTTCGCCTCGGACTCAGACTTGAGCGATGCGCACCAGCTAAGTTCTGGCGCTACGCTTCACATATGTTGCCTGTGTGGCGAGACGAAAACGCGACTCAGTCAATTGCTCGAGCATCAGCAAAGCCATCATAGTGAGGTGCAGGAAAAGCTCCCATACGTGTGTGAAGACTGCGATTTGAGTTTTGTAGCTGATGCTCTGCTCCAACGGCATCGCCGACGTGTCTGTGCTAAGCAGAATGCCAAGTTCGAGTGCCAGCAATGCAATCAGCGCTTTTACTGGCTTTCCAATTACGAGTTGCATGTGCAGCTGCAACACGAGTCCCATCCCGAGCTGCAGACGGATGTTGTCAATGAACAGGAGCGTAAGTCACGGATGAGAGGCAAGCGCCAGTCTAGAGCGGCAAAGCTGCAGTGCGGCGAATGCGAAAAGGTGTTCATCTGGCCGAAGGATCTGACGCGTCATAAGCGTCTGCACCAGCCACAGGCTTTGGCACAATACCAATGTTTGCTCTGCGACCGCAAGTTCCATCGCAAGGATGGGCTGAAGTCGCATATGCGCGTTCATGGCGAACAGCAGGCTGATGCTTCAGTTGCCAGTGAACAAGCTCCATTCATGCTGCAGCGCATGTCAGTGGTGCTGACCCAACTATGTCGACCCAATGGCTGTAAGCAAATTCAATGCATGATATGCCTCTCGCAACACGCCAAAATCTCTGATCTGCGTACACATTTGCTTGACCATCAGTATTCGGTCAAATTTGGAGAGGAACGAAGCCAACCAGAAAGCATTGCGGCGATTTCACGTTCGCTGTATCCAGAACTGCCCGAACCATTGGTGCAGCAGCAATTAATCGAACGTATCCAAAATGATCTGAGAAAAGGCGTTGACCTCGAAAGATTCATATCCATTACTAACGAGGCGGGCATTGAGCTCAGCCTGGACAGCAGCGAAACGGAAAGTGATTCGGACTCAGCCGAGGCAGTCAGAAGCAACAGCGGGCAACTGTATAGCTGTGAGCTATGTCAGCTAGAGCTGTCGCGCAAGCATCAGCTCTACGCCCATGAGCTGGAGCAGCATTCGTGGCAGCAAGCAACCCGTGTTTGTAGCTACTGCCAGGCGAGATTTGTAAATGAGCAGCTGCTGGAGCATCACTATCGCACGCTCTGTCGGAACGTGCACCGACGTTTCCTTTGCCGAAAATGCCCATTACGTTTCCGCTGGCGCGAGAATATGAAGTTGCACTCGGACGTGGCGCACAACGAAGCTAGAGGAGAGCAATCTACCTTAGGCATTGAGATGAACGGGACGCGCCTGTTACCCATCGTGAGCTACAACTGCACCGAATGCAACCGTAGCTTCAAAATGCAAAAGGATCTCACTCGACACACTTTGATGCATGCCCAGGAGTCGAGCATTTACCGTTGCCGCTGGTGTGCACGACGTTTTTATCGACAGGCTAATCTCCTGCAGCACATTGAGCGACACGGCATTAGCGCCGAACAACTGCCCTATGCTGAGGCACTGCTCAATGCTAGCCGTCATCCTCATGGCCAGAAGTGTATCCAGTGCAAGGTGTGTAACGTGACCTACCCTACAATTGCTGCGCTGCGCAGCCATCTTCAATCAGCGCCAGCAGGCACACATCATGAGTATGGCTCGCTGCTCAACTACTCAATCACCAATCAGCTGGGATACGAGCTGCATCTGGAAGACTCGGAAACGGATGAGGATGCCAAGCCACCAGGTACGCCCACGCACTACACCTGCAGCATATGCCAGCTGCGCTGTGCGCGCAAGTTTGAGCTGCATCAGCATCAGCAAGCGATGCATCGACTGGAACGTATAAACGAGGGTTGTGATGTCTGCATTTTTAAAAGTGTCTCAGCAGATCTCATTGCCTACCATCAACGCGTCTTGTGCAACAATACGGAGAAACACTTCAAATGCTCCAAGTGCGGCTACAAGTTTATGTGGGAAATGAATTTGGCGCAGCATATGAAGTTGCAGCATCCCAGCAGCGATGGCAGCGAAACGCAGCAGAATGCAAGTTCTTTGCCTCCACAAGAGGTTCCCAGCGCAGAGTGCCAGGTTTTTCAATGCGGACAGTGTCCTAGTAAATATAATCGCAAGGATCGTCTCACTGCACATGTAAAGAAATGTCATACAGCGGGAGCAAGTGGTTCTACGGCTGCGGCAGAGAAGCTTATGAAAAATTCAACAGGAGCCAAGCAGCAGAAGAGCTTTCTCTGCGCTTTCTGCGGTAAGGCGGTTAGCTCCTCGTCCAATCTGATTATACATATACGTCGCCACACTGGCGAGAAGCCTTTTAAGTGTGACTATTGCGACATGGCGTTTCCACGTTCCTCCGATCTCCAGTGCCATCGACGCACTCACACGGGCGAACGGCCGCACGTCTGCACCGTTTGCCAGAAGGGCTTCGCCCGATCCTACAAGCTGCAGCAGCACATGCGCATCCACAATGGCGAGCGACCATACAAGTGTACTTATTGTGACAAGAGTTTCACTCAGTCAAATGATCTGACTCTTCACATCCGACGACACACAGGCGAACGTCCCTATCAGTGCAATACGTGCGGCGAACGTTTTATTCAGGGCACAGCCCTGAAGAATCATCGCATGCAACATGGACACCACGACACGGAAGTGGACCAGGCCACTGATAACTAA
Protein Sequence: MLPTDICRTCTLHDDCLFPLTTRTDKYENKSLNEMLLELTQNDPLLEHTDDSLPQHLCSGCLHKLEAAYAFVLQARHAQEQLLLQLRKSLQPQCLDEMPIDINLQHIKTEMIVDMQPASKAKSEEDEAEAEEREQDMAVVAIPALKWQPNSDSESNQTAAHEQDIDFKPKQLRRSARKAKTYTDSENEATSTDATSLPIKRRRGRPARVNTEAINEEGRHVCEVCGKSFSWYRDMQRHTRIHFEQPTFVCDSCGKSFLRKDKYMFHLRSHEKRAAKCQATQLSTEWCFAERLYNSGRLKQAECKLCGSKYQRIGELREHMACHKSIETLSKLSLESDVIRKHFAKEQQQVDLELIKQHICADIDRGREHLDKYCAVVNAYGYELCLSDSDEEAADQSPKYKCRPCNINFTRKYRLMRHTLEEHTQTEPAVYWQRCDVCQIGFVCTIMLEQHQRTQCHNKLKRYSCPNCPGKFIWQQNLDQHACSQRSNQLDEQRQRQQKQCCLCDIQLNTMFELRAHLLSHQDGRSGIHPEQQATFFRTYYPNGLDCSLSELSARIAADFKAEDYGRYFNANTKNGEELDFFASDSDLSDAHQLSSGATLHICCLCGETKTRLSQLLEHQQSHHSEVQEKLPYVCEDCDLSFVADALLQRHRRRVCAKQNAKFECQQCNQRFYWLSNYELHVQLQHESHPELQTDVVNEQERKSRMRGKRQSRAAKLQCGECEKVFIWPKDLTRHKRLHQPQALAQYQCLLCDRKFHRKDGLKSHMRVHGEQQADASVASEQAPFMLQRMSVVLTQLCRPNGCKQIQCMICLSQHAKISDLRTHLLDHQYSVKFGEERSQPESIAAISRSLYPELPEPLVQQQLIERIQNDLRKGVDLERFISITNEAGIELSLDSSETESDSDSAEAVRSNSGQLYSCELCQLELSRKHQLYAHELEQHSWQQATRVCSYCQARFVNEQLLEHHYRTLCRNVHRRFLCRKCPLRFRWRENMKLHSDVAHNEARGEQSTLGIEMNGTRLLPIVSYNCTECNRSFKMQKDLTRHTLMHAQESSIYRCRWCARRFYRQANLLQHIERHGISAEQLPYAEALLNASRHPHGQKCIQCKVCNVTYPTIAALRSHLQSAPAGTHHEYGSLLNYSITNQLGYELHLEDSETDEDAKPPGTPTHYTCSICQLRCARKFELHQHQQAMHRLERINEGCDVCIFKSVSADLIAYHQRVLCNNTEKHFKCSKCGYKFMWEMNLAQHMKLQHPSSDGSETQQNASSLPPQEVPSAECQVFQCGQCPSKYNRKDRLTAHVKKCHTAGASGSTAAAEKLMKNSTGAKQQKSFLCAFCGKAVSSSSNLIIHIRRHTGEKPFKCDYCDMAFPRSSDLQCHRRTHTGERPHVCTVCQKGFARSYKLQQHMRIHNGERPYKCTYCDKSFTQSNDLTLHIRRHTGERPYQCNTCGERFIQGTALKNHRMQHGHHDTEVDQATDN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00509945;
90% Identity: iTF_00554509; iTF_00473197; iTF_00540502; iTF_00551721;
80% Identity: -