Basic Information

Insect: Drosophila aldrichi
Gene Symbol: -
Assembly: GCA_035045965.1
Location: JAWNOM010000199.1:3949734-3954357[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 26 0.001 0.076 13.6 1.3 1 23 221 243 221 243 0.97

2 26 0.043 3.2 8.5 2.0 1 23 249 271 249 271 0.97

3 26 0.092 6.8 7.4 0.8 2 20 303 321 303 331 0.96

4 26 0.016 1.2 9.8 1.9 1 23 401 424 401 424 0.93

5 26 3.9 2.9e+02 2.3 3.5 2 23 435 458 434 458 0.92

6 26 0.48 36 5.2 0.3 1 20 464 483 464 485 0.92

7 26 0.68 51 4.7 0.7 2 23 494 515 493 515 0.97

8 26 1.5 1.1e+02 3.6 5.8 3 23 597 617 595 618 0.93

9 26 0.0018 0.13 12.8 0.0 1 22 627 648 627 648 0.96

10 26 1.5 1.1e+02 3.7 0.4 1 23 657 680 657 680 0.86

11 26 0.00083 0.062 13.9 0.2 2 23 708 729 707 729 0.97

12 26 1.4e-05 0.001 19.5 5.7 1 23 737 759 737 759 0.99

13 26 0.029 2.1 9.0 1.4 1 23 907 930 907 930 0.92

14 26 0.0015 0.11 13.0 1.0 2 22 938 958 938 958 0.96

15 26 2.4 1.8e+02 3.0 0.4 1 23 967 990 967 990 0.85

16 26 1.1e-05 0.0008 19.8 2.4 1 23 1015 1037 1015 1037 0.98

17 26 0.00013 0.0099 16.4 0.9 1 23 1044 1066 1044 1066 0.98

18 26 0.0056 0.42 11.2 0.0 2 21 1093 1112 1092 1113 0.94

19 26 0.04 3 8.6 4.5 1 23 1158 1181 1158 1181 0.96

20 26 0.0078 0.58 10.8 0.6 1 23 1218 1241 1218 1241 0.95

21 26 0.014 1 10.0 3.1 1 23 1269 1292 1269 1292 0.97

22 26 1.3e-05 0.00097 19.5 0.1 2 23 1320 1341 1319 1341 0.95

23 26 4.5e-05 0.0033 17.9 2.9 1 23 1347 1369 1347 1369 0.99

24 26 2.2e-06 0.00016 22.0 2.0 1 23 1375 1397 1375 1397 0.97

25 26 5.6e-08 4.1e-06 27.0 2.4 1 23 1403 1425 1403 1425 0.99

26 26 0.00011 0.0083 16.6 0.6 1 23 1431 1453 1431 1453 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	26	0.001	0.076	13.6	1.3	1	23	221	243	221	243	0.97
2	26	0.043	3.2	8.5	2.0	1	23	249	271	249	271	0.97
3	26	0.092	6.8	7.4	0.8	2	20	303	321	303	331	0.96
4	26	0.016	1.2	9.8	1.9	1	23	401	424	401	424	0.93
5	26	3.9	2.9e+02	2.3	3.5	2	23	435	458	434	458	0.92
6	26	0.48	36	5.2	0.3	1	20	464	483	464	485	0.92
7	26	0.68	51	4.7	0.7	2	23	494	515	493	515	0.97
8	26	1.5	1.1e+02	3.6	5.8	3	23	597	617	595	618	0.93
9	26	0.0018	0.13	12.8	0.0	1	22	627	648	627	648	0.96
10	26	1.5	1.1e+02	3.7	0.4	1	23	657	680	657	680	0.86
11	26	0.00083	0.062	13.9	0.2	2	23	708	729	707	729	0.97
12	26	1.4e-05	0.001	19.5	5.7	1	23	737	759	737	759	0.99
13	26	0.029	2.1	9.0	1.4	1	23	907	930	907	930	0.92
14	26	0.0015	0.11	13.0	1.0	2	22	938	958	938	958	0.96
15	26	2.4	1.8e+02	3.0	0.4	1	23	967	990	967	990	0.85
16	26	1.1e-05	0.0008	19.8	2.4	1	23	1015	1037	1015	1037	0.98
17	26	0.00013	0.0099	16.4	0.9	1	23	1044	1066	1044	1066	0.98
18	26	0.0056	0.42	11.2	0.0	2	21	1093	1112	1092	1113	0.94
19	26	0.04	3	8.6	4.5	1	23	1158	1181	1158	1181	0.96
20	26	0.0078	0.58	10.8	0.6	1	23	1218	1241	1218	1241	0.95
21	26	0.014	1	10.0	3.1	1	23	1269	1292	1269	1292	0.97
22	26	1.3e-05	0.00097	19.5	0.1	2	23	1320	1341	1319	1341	0.95
23	26	4.5e-05	0.0033	17.9	2.9	1	23	1347	1369	1347	1369	0.99
24	26	2.2e-06	0.00016	22.0	2.0	1	23	1375	1397	1375	1397	0.97
25	26	5.6e-08	4.1e-06	27.0	2.4	1	23	1403	1425	1403	1425	0.99
26	26	0.00011	0.0083	16.6	0.6	1	23	1431	1453	1431	1453	0.98

Sequence Information

Coding Sequence: ATGTTGCCGACAAATATTTGTCGTACATGCACACTGTATGATGATAGCTTGTTTCCACTTGCGACCCGCACagacaaatatgaaaataaaagtttaaatgACATGTTACTTGAATTGACACAAAATGATCCCCTGCTGGAGCCTACGGATGACAGTCTTCCGCAGCACTTGTGTAGTGGCTGCTTGCACAAGTTGGAGGCAGCGTATGCGTTTGTATTACAGGCGCGCCAAGCTCAagagcaattgttgttgcagctgcgcaAAGGCTTGCAAACACAGTGCTTGGATGAGATGCCTATAGACATTAACGTGCAGCACATCAAAACCGAGATGATCGTTGACATGCAACTAACTAGCAAAGCCAAGAGTGAAGAAGATGAGACGGAGGCTGAAGAGAGGGAGCAAGACATGGCTGCAGTGGCTATTCCAGCCCTGAAATGGCAGCCAGACAGCGACAGTGAGAACAATCAGACTGCTGCTGATGAGCAGGATATAGACCTTAAGCCCAAGCAGTTGCGGCGCAGCGCACGTAAAGCCAAAGCCTACACAGATAGCGAAAATGAAGCAACATCTGCCGATGCAACTCCCTTGCCTATCAAACGGCGCCGAGGTCGCCCAGCTCGTTTTTCCAAAACGGAGACAATCAACGAAGAAGGAAGACATGTGTGCGAGGTTTGTGGAAAGAGCTTCTCCTGGTACCGCGACATGCAACGCCACTCGCGCATTCACTTCGAGCAACCGACCTTCGTGTGTGACAGTTGTGGGAAGAGCTTCTTGCGCAAAGACAAATACATGTTTCATTTGCGTTCGCATGAAAAGCGTGCAGTCAAGTGTCAGGCCACTCAATTGAGCACCGAGTGGTGTTTTGCTGAACGTCTCTACAACTCCGGCCGACTTAAACAGGCGGAGTGTAAACTGTGCGGCTCGAAATACCAGCGTATAGGGGAGCTGCGCAAGCATATGGCATGCCATAAGAGCATTGAGACATTGTCCGAACTGAGTCTGGAGAGCGATGTAATCAGAGAACAGTTTGctgaagagcagcaacaggtcGACTTGGAAGTGATCAAACAACATGTATGTGCTGACATTGCCAGAGGACGTGAGCAGCTGGACAAATACTACGCTGTGGTCAACGCGTACGGTTATGAGCTCTGTCTTAGCGACTCAGACGAAGAAGCAGCTGATCAACCGGCTAAATACCAGTGTGGTCCATGCAACATTCACTTCACGCGCAAATATCGCCTTATGCGGCACACACTTGAGGAACACACACAGGAGGAACCAACAGTGTCTTGGCAACGCTGTGATGTTTGCCAAATTGGTTTTGTGTGTACTACATTGTTGGAGCAACATCAACGGACGCAGTGCCACAACAAACTTAAGCGTTACAGTTGTCCCAACTGCCCAGGTAAATTTATTTGGCAGCAGAACCTGGAGCAGCATGCGTGCTCGCAACGAACCAAGCGGCAGAAAAAGCAGTGCTGTCTCTGTGATATCGAATTGAACACCATGCTCGAATTACGCGCCCATTTGCTTAGCCATCAAGATGGACGCAGTGGGATACATCCAGAGCAGCAGGCGACCTTCTTCCGCACTTACTATCCCAATGGCCTTGACTGCAGTTTGTCGGAGCTGGGCGCACGTATTGCCGCTGACTTTAAGGCGGAGGATTATGGGCGATACTTTAATGCCAAAACGAGAAACGGCGAGGAGTTGGATTTCTTCGCTTCAGATTCAGACTTGAGTGATGCGGACCAGCTGAGTTGTAACGGTACTATTCACTTATGTTGCCTGTGTGGCGAGACGAAAACACGTCTCAGTCAATTGCTCGAGCATCAGCAAAGCCATCATAGTGAGGTGCAGGAAAAGCTCCCATACGTGTGTGAAGACTGCGATCTGAGCTTTGTAGCTGATGCGCTACTCCAACGGCATCGCCGACGTGTTTGTGCTAAGCAGCATGCCAAGTACGAGTGCCAGCAGTGCAGTCAGCGCTTTTACTGGCTTCCCAATTACGAGTTGCATGTGCAGCTGCAACACGAAACACAAGGCGAGCTGCAGCCGGAACAGGAGCGGGAGTCACGGATGAGAGGCAAGCGCCAGTCTACAGCGGCCAAGCTGCAGTGCGGCGAATGCGAAAAGGTGTTCGTCTGGCCGAAGGATCTGACGCGTCATAAGCGGCTGCACCAGCCACAGGCTTTGGCACAATACCAATGCTTGCACTGTGACCGCAAGTTTCATCGAAAGGATGGGCTGAAGTCGCATATGCGCGTGCATGGTGAACAGCAGGCTGATGCTTCAGTTGTCAGTGAACACGTTCCATCCATGCTGCAGCGCATGTCAGTGGTGCTGACCCAACTATGTCGACCTAATGGCtgcaagcaaattaaatgcatgaTATGTCTCTCACAACACAGCAAAATCTCAGATCTGCGCACTCATTTGCTTGATCATCAGTATTCCGTCAAATTCGGAGAGGAGCGGAGCCAACCAGAGAGCATTGCGGGCATTTCACGTTCGCTGTATCCAGAACTAGCAGAACCATTGGAACAGCAGCAATTAATCGAACGCATCCAAAGTGATCTGACAAAAGGCGTGGACCTAGAAAGATTCATCTCCATTACCAACGAGGCAGGCATTGAGCTCAGCCTAGACAGCAGCGAAACGGAAACCGATTCGGATTCAGCCGAGGcagccaaaagcaacagcGGGCAACTATATAGCTGTGAGCTATGCCAGCTAAAGCTGTCGCGCAAGCATCAACTCTACGCTCATGAGCTGGAGCAGCATACGTGCCAGCAAGCAACTCGTGTTTGTAGCTACTGCCAGACGAGATTCGTAAatgagcagctgttgcagcatcACTATCGCACGCTCTGTCGCAACGTGCACCGACGCTTCCTTTGTCGTAAATGCCCATTACGTTTCCGCTGGCGCGAGAATATGAAGTTGCACTCGGACGTGGCGCACAACGAAGCTAGAGGAGAGCAATCGAACTTGGGCATTAAGTTGAACGGGACGCGCCTGTTACCCATCGTGAGTTACAACTGCACTGAATGCAACCGAAGCTTCAAAATGCAAAAGGATCTCACCAGGCACACTCTGATGCATGCCCAGGAGTCGAGCATTTACCGTTGTCGCTGGTGTGCACGACGCTTCTATCGCCAGGCCAATCTTCTACAGCACATTGAGCGTCACGGCATTAGCGCTGAACAACTGCCCTATGCTGAGGCACTGCTTAATGCTAGTCGTCATCCCCATGGCCAGAAGTGTATCCAGTGCAAGGTGTGTAATGTGACCTTCCCCACCATTGCTGCGCTGCGCAGCCATCTTCAATCGGCGCCAGCAGGCACACATCATGAGTATGGCTCGCTGCTCAACTACTCAATTACCAATCAGCTGGGATACGAGTTGCATCTGGAAGACTCGGAAACGGATGAGGATGCTAAGCCACCAGGCACGCCCACGCACTACACCTGCAGCTTATGCCAGCTGCGCTGTGCGCGCAAGTTTGAgctgcatcagcatcagcaagcTATGCATCGACTGGAACGTATAAACGAGGGCTGCGATGCCTGCATCTTTAAGAGTGTCTCAGCAGATCTCATTGCCTACCATCGGCGCGTCTTGTGCAACAATACGGAGAAACGCTTCACATGCTCCAAGTGCGGCTACAAGTTTATGTGGGAAACGAATTTGGCGCAACATATGGAGTTGCAGCATCCCAGCAGCGATGGCAGCGAAACGCAGCAAAATGCAAACTCGTTGCCTGCACCGGAGGTACCCAGCGCAGAGTGCCACATTTTTCAGTGCGGGCAGTGCCCTAGTAAATATAATCGCAAGGATCGTCTTACTGCACATGTAAAGAAATGTCACGCAGCGGGAGTGAATGGTCCTACGGCTGCAGCAGAGAAGCTTTTGAAAAATTCAACTGGCGCCAAGCAGCAGAAGAGCTTTCTCTGCGCTTTCTGCGGCAAGGCGGTTAGCTCCTCGTCCAATCTGATTATACACATACGTCGCCACACTGGCGAGAAGCCTTTTAAGTGTGACTATTGCGACATGGCCTTTCCACGTTCCTCCGATCTGCAGTGCCATCGACGCACTCACACTGGCGAACGGCCGCACGTCTGCACTGTTTGCCAGAAGGGCTTTGCCCGATCCtacaagctgcagcagcacatgcGCATCCACAATGGCGAGCGACCATACAAGTGTACTTATTGTGACAAGAGTTTCACTCAGTCGAATGATCTGACTCTTCACATACGACGGCACACAGGCGAGCGTCCCTATCAGTGCAATACGTGCGGCGAACGTTTTATTCAGGGCACAGCTCTGAAGAATCATCGCATGCAACATGGACACCACGACACGGAAATGGACCAGGTCAAGGATAACTAA
Protein Sequence: MLPTNICRTCTLYDDSLFPLATRTDKYENKSLNDMLLELTQNDPLLEPTDDSLPQHLCSGCLHKLEAAYAFVLQARQAQEQLLLQLRKGLQTQCLDEMPIDINVQHIKTEMIVDMQLTSKAKSEEDETEAEEREQDMAAVAIPALKWQPDSDSENNQTAADEQDIDLKPKQLRRSARKAKAYTDSENEATSADATPLPIKRRRGRPARFSKTETINEEGRHVCEVCGKSFSWYRDMQRHSRIHFEQPTFVCDSCGKSFLRKDKYMFHLRSHEKRAVKCQATQLSTEWCFAERLYNSGRLKQAECKLCGSKYQRIGELRKHMACHKSIETLSELSLESDVIREQFAEEQQQVDLEVIKQHVCADIARGREQLDKYYAVVNAYGYELCLSDSDEEAADQPAKYQCGPCNIHFTRKYRLMRHTLEEHTQEEPTVSWQRCDVCQIGFVCTTLLEQHQRTQCHNKLKRYSCPNCPGKFIWQQNLEQHACSQRTKRQKKQCCLCDIELNTMLELRAHLLSHQDGRSGIHPEQQATFFRTYYPNGLDCSLSELGARIAADFKAEDYGRYFNAKTRNGEELDFFASDSDLSDADQLSCNGTIHLCCLCGETKTRLSQLLEHQQSHHSEVQEKLPYVCEDCDLSFVADALLQRHRRRVCAKQHAKYECQQCSQRFYWLPNYELHVQLQHETQGELQPEQERESRMRGKRQSTAAKLQCGECEKVFVWPKDLTRHKRLHQPQALAQYQCLHCDRKFHRKDGLKSHMRVHGEQQADASVVSEHVPSMLQRMSVVLTQLCRPNGCKQIKCMICLSQHSKISDLRTHLLDHQYSVKFGEERSQPESIAGISRSLYPELAEPLEQQQLIERIQSDLTKGVDLERFISITNEAGIELSLDSSETETDSDSAEAAKSNSGQLYSCELCQLKLSRKHQLYAHELEQHTCQQATRVCSYCQTRFVNEQLLQHHYRTLCRNVHRRFLCRKCPLRFRWRENMKLHSDVAHNEARGEQSNLGIKLNGTRLLPIVSYNCTECNRSFKMQKDLTRHTLMHAQESSIYRCRWCARRFYRQANLLQHIERHGISAEQLPYAEALLNASRHPHGQKCIQCKVCNVTFPTIAALRSHLQSAPAGTHHEYGSLLNYSITNQLGYELHLEDSETDEDAKPPGTPTHYTCSLCQLRCARKFELHQHQQAMHRLERINEGCDACIFKSVSADLIAYHRRVLCNNTEKRFTCSKCGYKFMWETNLAQHMELQHPSSDGSETQQNANSLPAPEVPSAECHIFQCGQCPSKYNRKDRLTAHVKKCHAAGVNGPTAAAEKLLKNSTGAKQQKSFLCAFCGKAVSSSSNLIIHIRRHTGEKPFKCDYCDMAFPRSSDLQCHRRTHTGERPHVCTVCQKGFARSYKLQQHMRIHNGERPYKCTYCDKSFTQSNDLTLHIRRHTGERPYQCNTCGERFIQGTALKNHRMQHGHHDTEMDQVKDN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00509945;
90% Identity: iTF_00549680;
80% Identity: -