Basic Information

Insect: Drosophila mulleri
Gene Symbol: -
Assembly: GCA_035047565.1
Location: JAWNPK010000168.1:1764503-1769150[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 26 0.001 0.079 13.6 1.3 1 23 221 243 221 243 0.97

2 26 0.015 1.1 9.9 2.1 1 23 249 271 249 271 0.97

3 26 0.092 7.1 7.4 0.8 2 20 303 321 303 331 0.96

4 26 0.0086 0.66 10.7 0.7 1 23 401 424 401 424 0.93

5 26 9.3 7.2e+02 1.1 2.8 2 23 435 458 435 458 0.91

6 26 1.1 85 4.0 0.5 1 20 464 483 464 485 0.92

7 26 5.2 4e+02 1.9 1.5 3 23 501 521 500 521 0.95

8 26 4.2 3.2e+02 2.2 7.3 1 23 601 623 601 624 0.94

9 26 0.006 0.46 11.2 0.1 1 22 633 654 633 654 0.95

10 26 0.99 77 4.2 1.7 1 23 663 686 663 686 0.93

11 26 0.001 0.079 13.6 0.2 2 23 714 735 713 735 0.97

12 26 1.3e-05 0.001 19.5 5.7 1 23 743 765 743 765 0.99

13 26 0.014 1.1 10.0 0.6 1 23 914 937 914 937 0.92

14 26 0.0014 0.11 13.2 0.7 2 22 945 965 945 965 0.96

15 26 2.4 1.8e+02 3.0 0.4 1 23 974 997 974 997 0.85

16 26 1.1e-05 0.00083 19.8 2.4 1 23 1022 1044 1022 1044 0.98

17 26 0.00013 0.01 16.3 0.9 1 23 1051 1073 1051 1073 0.98

18 26 0.0056 0.43 11.2 0.0 2 21 1100 1119 1099 1120 0.94

19 26 0.011 0.83 10.4 4.1 1 23 1165 1188 1165 1188 0.96

20 26 0.0085 0.65 10.7 1.8 1 23 1225 1248 1225 1248 0.94

21 26 0.014 1.1 10.0 3.1 1 23 1276 1299 1276 1299 0.97

22 26 1.3e-05 0.001 19.5 0.1 2 23 1327 1348 1326 1348 0.95

23 26 4.5e-05 0.0034 17.8 2.9 1 23 1354 1376 1354 1376 0.99

24 26 2.2e-06 0.00017 22.0 2.0 1 23 1382 1404 1382 1404 0.97

25 26 5.6e-08 4.3e-06 27.0 2.4 1 23 1410 1432 1410 1432 0.99

26 26 0.00011 0.0086 16.6 0.6 1 23 1438 1460 1438 1460 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	26	0.001	0.079	13.6	1.3	1	23	221	243	221	243	0.97
2	26	0.015	1.1	9.9	2.1	1	23	249	271	249	271	0.97
3	26	0.092	7.1	7.4	0.8	2	20	303	321	303	331	0.96
4	26	0.0086	0.66	10.7	0.7	1	23	401	424	401	424	0.93
5	26	9.3	7.2e+02	1.1	2.8	2	23	435	458	435	458	0.91
6	26	1.1	85	4.0	0.5	1	20	464	483	464	485	0.92
7	26	5.2	4e+02	1.9	1.5	3	23	501	521	500	521	0.95
8	26	4.2	3.2e+02	2.2	7.3	1	23	601	623	601	624	0.94
9	26	0.006	0.46	11.2	0.1	1	22	633	654	633	654	0.95
10	26	0.99	77	4.2	1.7	1	23	663	686	663	686	0.93
11	26	0.001	0.079	13.6	0.2	2	23	714	735	713	735	0.97
12	26	1.3e-05	0.001	19.5	5.7	1	23	743	765	743	765	0.99
13	26	0.014	1.1	10.0	0.6	1	23	914	937	914	937	0.92
14	26	0.0014	0.11	13.2	0.7	2	22	945	965	945	965	0.96
15	26	2.4	1.8e+02	3.0	0.4	1	23	974	997	974	997	0.85
16	26	1.1e-05	0.00083	19.8	2.4	1	23	1022	1044	1022	1044	0.98
17	26	0.00013	0.01	16.3	0.9	1	23	1051	1073	1051	1073	0.98
18	26	0.0056	0.43	11.2	0.0	2	21	1100	1119	1099	1120	0.94
19	26	0.011	0.83	10.4	4.1	1	23	1165	1188	1165	1188	0.96
20	26	0.0085	0.65	10.7	1.8	1	23	1225	1248	1225	1248	0.94
21	26	0.014	1.1	10.0	3.1	1	23	1276	1299	1276	1299	0.97
22	26	1.3e-05	0.001	19.5	0.1	2	23	1327	1348	1326	1348	0.95
23	26	4.5e-05	0.0034	17.8	2.9	1	23	1354	1376	1354	1376	0.99
24	26	2.2e-06	0.00017	22.0	2.0	1	23	1382	1404	1382	1404	0.97
25	26	5.6e-08	4.3e-06	27.0	2.4	1	23	1410	1432	1410	1432	0.99
26	26	0.00011	0.0086	16.6	0.6	1	23	1438	1460	1438	1460	0.98

Sequence Information

Coding Sequence: ATGTTGCCGACAGATATATGTCGTACATGCACACTGCATGATGATAGCTTGTTTCCACTCGCTACACGCAcagataaatatgaaaataaaagtttaaatgACATGTTACTTGAATTGACTCAAAATGATCCCCTGCTGGAGCATACGGATGACAGTCTGCCGCAGCACTTGTGTAGTGGCTGCTTGCACAAGTTGGAGGCAGCATATGCGTTTGTATTGCAGGCGCGCCACGCTCAagagcaattgttgttgcagctgcgcaAAGGCTTGCAAACACAGTGCTTGGATGAGATGCCCATAGACATTAACTTGCAGCACATCAAAACCGAGATGATCGTTGACATGCAACTAGCTAGCAAAGCCAAGAGTGAAGAAGATGAGGCGGAGGCTGAAGAGAGGGATCAAGACATGGCTGCTGTGACTATTCCAGTCCTGAAATGGCAGCCAGACAGCGACAGTGAGAGCAATCACACTGCTGCTAATGAACAGGACGTAGGCATTAAGCCCAAGCAGTTGCGACGCAGCGCACGTAAAGCCAAAGCCTACACAGATAGCGAAAATGAAGCAACGTCTGCCGATGCAACTCCCTTGCCTATAAAACGGCGTCGTGGTCGCCCAGCACGTCTTTCCAAAACGGATGCTATCAACGAAGAAGGACGACATGTGTGCGAGGTTTGTGGAAAGAGCTTCTCCTGGTACCGCGACATGCAACGCCACTCGCGCATTCATTTCGAGCAACCGACCTTCGTATGTGACACTTGTGGCAAGAGCTTCTTGCGCAAAGACAAATACATGTTTCATCTGCGTTCACATGAAAAGCGTGCAGTCAAGTGTCAGGCCACGCAATTGAGCACCGAGTGGTGTTTCGCTGAACGTCTCTACAACTCCGGCCGACTCAAACAAGCGGAGTGTAAGCTGTGCGGCTCGAAATACCAGCGTATAGGGGAGCTGCGAAAGCATATGGCGTGCCATAAGAGCATTGAGACTTTGTCCGAACTGAGTCTGGAGAGCGATGTTATCAGAGAACAGTTTgctgaagagcagcagcagctcgactTGGAACTGATCAAACAATACATATGTGCTGACATTTCCAGAGGACGTGAGCAGCTGGACAAATACTGCGCTGTGGTCAACGCGTACGGCTATGAGCTCTGTCTTAGCGACTCAGACGAAGAAGCAGCTGATCAACCGGCTAAATACCAGTGTGGTCCATGCAACATCAACTTCACGCGCAAATATCGTCTTATGCGGCACACACTGGAGGAACACACACAGGCGGAACCAGCAGTGTCTTGGCGACGCTGTGATGTTTGCCAAATTGGTTTTGGGTGTACTGCAATGTTGGAGCAACATCAACGCACGCAGTGCCACAACAAACTTAAGCGATACAGTTGTTCTAACTGCCCAGGTAAATTTATTTGGCAGCGCAACCTGGAGCAACATGCGTGCTCGCAACGTAGCAAGCAGCTCGACGagcagcggcgacagcaaAAGCTGTGTTGTCTCTGTGATAGCCAATTGAACACCATGTTCGAATTACGCGCCCATTTGCTTAGCCATCAAGATGGACGCAGTGGGATACATCCAGAGCAGCAGGCGGCGTTCTTTCGCACCTACTATCCCAATGGCCTTGACTGCAGCATGTCGGAGCTGAGCGAACGGATTTCCGCCGACTTTAAGGCGGAGGATTATGGGCGATACTTTAATGCCAGAACGAGGAATGGCGAGGAACTCGATTTCTTCGCCTCGGACTCTGACTTGAGTGATGTTGACCAGCTGAGTTGTAGCGGTACGATTCACATATGTTGCCTGTGTGGCGAGACGAAATCGCGTCTCAGTCAATTGCTCGAGCATCAGCATAGCCATCATAGTGAGGTGCAGGAAAAGCTCCCATACGCGTGCGACGACTGCAATTTGAGCTTTGTAGCTGATGCTCTGCTCCAACGGCATCGCCGACGTGTCTGTGCTAAGCAGCATGCCAAACACGAGTGCCAGCAATGCAGTCAGCGCTTTTACTGGCTTTCCAATTACGAGTTGCATGTGCAGCTGCAACACGAGACCCAGCCCGAGCTGCAGACGGAACAGGAGCGGGAGTCACGGGTGAGAGGCAGGCGCCAGTCTACAGCGGCCAAGCTGCAGTGCGGCGAATGCGAAAAGGTGTTCATCTGGCCGAAGGATCTGACGCGTCATAAGCGGCTGCACCAGCCACAGGCTTTGGCACAATACCAATGCTTGCACTGTGACCGCAAGTTTCATCGAAAGGATGGGCTGAAGTCGCATATGCGCGTGCATGGCGAACAGCAGGCTGATGCTTCAGTTGCCAGTGAACAAGCTCCATCCATGCTGCAGCGCATGTCAGTGGTGCTGACCCAACTATGTCGACCTAATGGCTGCAAGCAAATTCAATGCATGATATGTCTGTCGCAACACAGCAGAATCTCTGATCTGCGCACTCATTTGCTTGATCATCAGTATTCCGTCAAATTTGGAGAGGAGCGGAGCCAACCAGAGAGCATTGCGGGCATTTCACGTTCGCTATATCCAGAACTAGACGAACCattagagcagcagcaattaaTCGAACGCATCCAAAGTGATCTGACAAAAGGCGTGGACCTCGAAAGATTCATATCCATTACCAACGAGGCGGGCATTGAGCTCAGCCTGGACAGCAGCGAAACGGAAACCGACTCGGACTCTGCCGACTCTGCCGTCAGAAGCAACAGCGGGCAAATATATAGCTGTGAGCTATGCCAGCTGAAGCTGTCTCGCAAGTATCAACTCTACGCTCatgagctggagcagcattCGTGCCAGCAAGCAACTCGTGTTTGTAACTACTGCCAGACGAGATTCGTAAATGAGCAGCTGTTGGAGCATCACTATCGCACGCTCTGTCGCAACGTACACCGACGCTTCCTTTGTCGTAAATGCCCCTTACGTTTCCGCTGGCGCGAGAATATGAAGTTGCATTCGGACGTGGCGCACAAGGAAGCTGGAGGAGAGCCATCGAACTTGGGCATTAAGTTGAACGGGACGCGCCTGTTACCTATCGTGAGTTACAACTGCACCGAATGCAACCGTAGCttcaaaatgcaaaaggaTCTCACCAGGCACACTCTGATGCATGCCCAGGAGTCGAGCATTTACCGTTGTCGCTGGTGTGCACGACGTTTCTATCGCCAGGCCAATCTTCTGCAGCACATTGAGCGTCATGGCATTAGCGCCGAACAACTGCCCTATGCTGAGGCACTGCTCAACGCTAGTCGTCATCCCCATGGCCAGAAGTGTATCCAGTGCAAGGTGTGTAATGTGACCTTCCCCACCATTGCTGCGCTGCGCAGCCATCTTCAATCGGCGCCAGCAGGCACACATCACGAGTATGGCTCGCTGCTCAACTACTCGATTACCAATCAACTGGGATACGAGTTGCATTTGGAAGACTCGGAAACGGATGAGGATACTAAGCCACCAGGCACGCCCACGCACTACACCTGCAGCATATGCCAACTGCGCTGTGCGCGCAAGTTTGagctgcatcagcatcagcaagcGATGCATCGACTGGAACGTATAAACGAGGGCTGTGATGCCTGCATCTTTAAGAGTGTCTCAGCAGATCTCATTGCCTACCATCGGCGCGTCTTGTGCAACAATACGGAGAAACACTTCAAATGCTCCAAATGCGGCTATAAGTTTATGTGGGAAACGAATTTGGCGCACCATATGGAGTTGCAGCATCCCAGCAACGATGGCAGCGAAGCGCAGCAGAAtgcaagttcgttgcctgCACCGGAGGTACCCAGCGCAGAGTGCCAGATTTTTCAGTGCGGACAGTGCCCTAGTAAATATAATCGCAAGGATCGTCTGACTGCACATGTAAAGAAATGTCACGCAGCGGGAGTAAGTGGTCCTACGGCTGCAGCAGAGAAGCTTTTGAAAAATTCAACTGGCGCCAAGCAGCAGAAGAGCTTTCTCTGCGCTTTCTGCGGCAAGGCGGTTAGTTCCTCGTCCAATCTGATTATACACATACGTCGCCACACTGGCGAGAAGCCTTTTAAGTGTGACTATTGTGACATGGCTTTTCCACGTTCCTCCGATCTGCAGTGCCATCGACGCACTCACACGGGCGAACGGCCGCACGTCTGCACTGTTTGTCAGAAGGGCTTTGCCCGATCCTataagctgcagcagcacatgcGCATCCACAATGGCGAACGGCCATACAAGTGTACTTATTGTGACAAGAGTTTCACTCAGTCGAATGATCTAACACTTCACATACGACGGCACACAGGCGAACGTCCCTATCAGTGCAATACGTGCGGTGAGCGTTTTATTCAGGGCACAGCCCTAAAGAATCATCGTATGCAACATGGACACCATGACACGGAAATGGACCAGCTCAAGGATAACTAA
Protein Sequence: MLPTDICRTCTLHDDSLFPLATRTDKYENKSLNDMLLELTQNDPLLEHTDDSLPQHLCSGCLHKLEAAYAFVLQARHAQEQLLLQLRKGLQTQCLDEMPIDINLQHIKTEMIVDMQLASKAKSEEDEAEAEERDQDMAAVTIPVLKWQPDSDSESNHTAANEQDVGIKPKQLRRSARKAKAYTDSENEATSADATPLPIKRRRGRPARLSKTDAINEEGRHVCEVCGKSFSWYRDMQRHSRIHFEQPTFVCDTCGKSFLRKDKYMFHLRSHEKRAVKCQATQLSTEWCFAERLYNSGRLKQAECKLCGSKYQRIGELRKHMACHKSIETLSELSLESDVIREQFAEEQQQLDLELIKQYICADISRGREQLDKYCAVVNAYGYELCLSDSDEEAADQPAKYQCGPCNINFTRKYRLMRHTLEEHTQAEPAVSWRRCDVCQIGFGCTAMLEQHQRTQCHNKLKRYSCSNCPGKFIWQRNLEQHACSQRSKQLDEQRRQQKLCCLCDSQLNTMFELRAHLLSHQDGRSGIHPEQQAAFFRTYYPNGLDCSMSELSERISADFKAEDYGRYFNARTRNGEELDFFASDSDLSDVDQLSCSGTIHICCLCGETKSRLSQLLEHQHSHHSEVQEKLPYACDDCNLSFVADALLQRHRRRVCAKQHAKHECQQCSQRFYWLSNYELHVQLQHETQPELQTEQERESRVRGRRQSTAAKLQCGECEKVFIWPKDLTRHKRLHQPQALAQYQCLHCDRKFHRKDGLKSHMRVHGEQQADASVASEQAPSMLQRMSVVLTQLCRPNGCKQIQCMICLSQHSRISDLRTHLLDHQYSVKFGEERSQPESIAGISRSLYPELDEPLEQQQLIERIQSDLTKGVDLERFISITNEAGIELSLDSSETETDSDSADSAVRSNSGQIYSCELCQLKLSRKYQLYAHELEQHSCQQATRVCNYCQTRFVNEQLLEHHYRTLCRNVHRRFLCRKCPLRFRWRENMKLHSDVAHKEAGGEPSNLGIKLNGTRLLPIVSYNCTECNRSFKMQKDLTRHTLMHAQESSIYRCRWCARRFYRQANLLQHIERHGISAEQLPYAEALLNASRHPHGQKCIQCKVCNVTFPTIAALRSHLQSAPAGTHHEYGSLLNYSITNQLGYELHLEDSETDEDTKPPGTPTHYTCSICQLRCARKFELHQHQQAMHRLERINEGCDACIFKSVSADLIAYHRRVLCNNTEKHFKCSKCGYKFMWETNLAHHMELQHPSNDGSEAQQNASSLPAPEVPSAECQIFQCGQCPSKYNRKDRLTAHVKKCHAAGVSGPTAAAEKLLKNSTGAKQQKSFLCAFCGKAVSSSSNLIIHIRRHTGEKPFKCDYCDMAFPRSSDLQCHRRTHTGERPHVCTVCQKGFARSYKLQQHMRIHNGERPYKCTYCDKSFTQSNDLTLHIRRHTGERPYQCNTCGERFIQGTALKNHRMQHGHHDTEMDQLKDN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00509945;
90% Identity: iTF_00549680;
80% Identity: -