Basic Information

Insect: Drosophila melanica
Gene Symbol: -
Assembly: GCA_004143765.1
Location: SCDT01000093.1:262-7161[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 1.3e-05 0.0013 19.2 2.1 1 23 146 168 146 168 0.97

2 18 4.3e-06 0.00043 20.7 0.4 1 23 174 196 174 196 0.97

3 18 0.00063 0.063 13.9 0.9 1 23 202 224 202 224 0.95

4 18 9.1e-06 0.00091 19.7 3.1 1 23 230 252 230 252 0.97

5 18 2.1e-05 0.0021 18.6 4.7 1 23 258 280 258 280 0.99

6 18 3.8e-05 0.0038 17.8 5.7 1 23 286 308 286 308 0.97

7 18 1.8e-07 1.9e-05 25.0 4.3 1 23 314 336 314 336 0.98

8 18 6.6e-08 6.6e-06 26.4 2.4 1 23 342 364 342 364 0.97

9 18 3.9e-05 0.0039 17.7 6.7 1 23 370 392 370 392 0.97

10 18 6.7e-05 0.0067 17.0 6.5 1 23 398 420 398 420 0.98

11 18 6e-06 0.0006 20.3 4.5 1 23 426 448 426 448 0.98

12 18 4.3e-06 0.00044 20.7 8.1 1 23 454 476 454 476 0.98

13 18 3.5e-06 0.00035 21.0 7.6 1 23 482 504 482 504 0.97

14 18 4e-07 4e-05 24.0 7.7 1 23 510 532 510 532 0.98

15 18 0.00012 0.012 16.2 9.5 1 23 538 561 538 561 0.95

16 18 4.4e-05 0.0044 17.6 0.9 1 23 567 589 567 589 0.98

17 18 0.00048 0.048 14.3 3.4 1 23 599 621 599 621 0.97

18 18 5.5e-06 0.00055 20.4 1.6 1 23 627 650 627 650 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	1.3e-05	0.0013	19.2	2.1	1	23	146	168	146	168	0.97
2	18	4.3e-06	0.00043	20.7	0.4	1	23	174	196	174	196	0.97
3	18	0.00063	0.063	13.9	0.9	1	23	202	224	202	224	0.95
4	18	9.1e-06	0.00091	19.7	3.1	1	23	230	252	230	252	0.97
5	18	2.1e-05	0.0021	18.6	4.7	1	23	258	280	258	280	0.99
6	18	3.8e-05	0.0038	17.8	5.7	1	23	286	308	286	308	0.97
7	18	1.8e-07	1.9e-05	25.0	4.3	1	23	314	336	314	336	0.98
8	18	6.6e-08	6.6e-06	26.4	2.4	1	23	342	364	342	364	0.97
9	18	3.9e-05	0.0039	17.7	6.7	1	23	370	392	370	392	0.97
10	18	6.7e-05	0.0067	17.0	6.5	1	23	398	420	398	420	0.98
11	18	6e-06	0.0006	20.3	4.5	1	23	426	448	426	448	0.98
12	18	4.3e-06	0.00044	20.7	8.1	1	23	454	476	454	476	0.98
13	18	3.5e-06	0.00035	21.0	7.6	1	23	482	504	482	504	0.97
14	18	4e-07	4e-05	24.0	7.7	1	23	510	532	510	532	0.98
15	18	0.00012	0.012	16.2	9.5	1	23	538	561	538	561	0.95
16	18	4.4e-05	0.0044	17.6	0.9	1	23	567	589	567	589	0.98
17	18	0.00048	0.048	14.3	3.4	1	23	599	621	599	621	0.97
18	18	5.5e-06	0.00055	20.4	1.6	1	23	627	650	627	650	0.96

Sequence Information

Coding Sequence: ATGCAGCACGTGAGCGCTGCCAGTTCGGCACCTTCGGTGGTTTCAGCACCGGTGGTGACCACTGGCGGTGGCACCACCATCACTTTGGGCGGACCGCCGCCACTACCCAGTAACAAGTCGGAACATAAAGAGGACGGCGGCAAGCCGCCGCAcggcattgaaatgtataaaGTGAACATTGAGGATATATCACAGTTATTTACGTATCACGAGGTCTTTGGCAAAATCCACGGCGATGTGGTTAATCATGTTGCGGCGGGCAGCGCCACAGTGACAACCACTAGCTCCGGCAGCAACGGGGGGAATGGGGGCAATAACTCGACAACGACGACGGGTGAGTTGCTAATGCCGAAAATGGAGGGCGGCATTCATGGCGTCGATGGGCAGTCGAGCGTTGCGTTGGCGCCGGATGGCACGCCCATAGCGACTGGTACGCATGTTTGCGACATTTGTGGCAAAATGTTCCAGTTTCGTTATCAGCTAATTGTGCATCGCCGCTACCACAGCGAGCGCAAGCCGTTTATGTGTCAGGTGTGCGGTCAGGGCTTTACCACATCGCAGGATTTGACCCGTCATGGCAAGATTCACATTGGCGGTCCAATGTTCACCTGCATTGTGTGCTTCAATGTGTTTGCCAATAATACAAGTTTGGAGCGCCATATGAAACGGCATTCAACGGACAAGCCATTCGCCTGCACCATTTGCCAAAAGACTTTCGCACGCAAAGAGCATCTGGACAATCATTTTCGTTCGCATACGGGCGAAACGCCGTTCCGTTGCCAGTACTGCGCCAAGACGTTTACGCGCAAGGAGCACATGGTCAATCATGTGCGCAAACACACGGGTGAGACGCCACATCGTTGCGATATTTGTAAGAAGTCCTTCACGCGCAAGGAACACTATGTTAACCACTACATGTGGCACACTGGTCAAACACCGCATCAGTGCGATGTCTGCGGCAAGAAATACACGCGCAAGGAGCACCTAGCCAACCATATGCGCTCCCACACCAACGAGACGCCGTTCCGTTGCGAAATCTGCGGCAAGAGCTTTAGCCGCAAGGAGCACTTCACCAATCACATACTCTGGCATACAGGCGAGACGCCGCATCGGTGCGACTTCTGCTCCAAGACGTTTACGCGCAAGGAGCATTTGTTAAATCACGTGCGCCAGCACACGGGAGAGTCGCCGCATCGCTGCTCCTACTGCATGAAGACGTTCACGCGCAAGGAGCACCTGGTTAATCATATACGCCAGCACACGGGTGAGACACCGTTCAAGTGCACGTACTGCACAAAAGCGTTCACGCGCAAAGATCACATGGTTAATCATGTACGGCAACATACAGGCGAATCGCCGCACAAGTGCACATACTGCACAAAGACGTTTACGCGCAAGGAGCACCTCACGAATCATGTGCGACAGCACACGGGCGATTCGCCGCACCGTTGCAGCTATTGCAAGAAGACCTTCACCCGCAAGGAGCACCTGACGAACCATGTGCGCCTGCACACTGGAGATTCGCCGCACAAATGCGAATACTGCCAGAAGACGTTCACGCGCAAGGAGCATCTCAATAACCATATGCGCCAGCACTCGAGCGACAATCCGCATTGTTGCAACGTGTGCAACAAGCCGTTCACGCGCAAAGAGCATCTGATTAATCACATGTCACGCTGCCACACCGGCGATCGTCCCTTCACCTGCGAGACGTGCGGCAAGTCCTTCCCCCTCAAAGGCAACCTGCTGTTCCATCAGCGCAGCCACACCAAGGGCCAGGAATGCGAGCGCCCCTTTGCCTGCGAGAAGTGCCCCAAGAATTTCATATGCAAAGGTCACTTGGTCTCGCACATGCGCTCCCATTCGGGCGAGAAACCGCACGCGTGCACACTGTGCAGCAAGGCTTTCGTCGAGCGCGGCAATTTGAAGCGCCACATGAAGATGAACCACCCGGATGCTATGATGCCACCACCACCCgtgcatccgcatccgcaaaTACCGGCTGGTGTGCTGACCCAAGTCAAGCAGGAAGTGAAACCGATCATAATTCCCCATCACTCGGCGACGACCACGATGCACACCATACAGCAGATAACAGCGGGCGCTGCAGcggccggcgccggcgccgtaCATGATCCGAGCGCGCTGGCGCGTGCCGccatgcagctgcagcatctgcCCACAAATGTAGAGCAGCATCCGGTGGTTTACTAA
Protein Sequence: MQHVSAASSAPSVVSAPVVTTGGGTTITLGGPPPLPSNKSEHKEDGGKPPHGIEMYKVNIEDISQLFTYHEVFGKIHGDVVNHVAAGSATVTTTSSGSNGGNGGNNSTTTTGELLMPKMEGGIHGVDGQSSVALAPDGTPIATGTHVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHGKIHIGGPMFTCIVCFNVFANNTSLERHMKRHSTDKPFACTICQKTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRKHTGETPHRCDICKKSFTRKEHYVNHYMWHTGQTPHQCDVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFSRKEHFTNHILWHTGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCSYCMKTFTRKEHLVNHIRQHTGETPFKCTYCTKAFTRKDHMVNHVRQHTGESPHKCTYCTKTFTRKEHLTNHVRQHTGDSPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRKEHLINHMSRCHTGDRPFTCETCGKSFPLKGNLLFHQRSHTKGQECERPFACEKCPKNFICKGHLVSHMRSHSGEKPHACTLCSKAFVERGNLKRHMKMNHPDAMMPPPPVHPHPQIPAGVLTQVKQEVKPIIIPHHSATTTMHTIQQITAGAAAAGAGAVHDPSALARAAMQLQHLPTNVEQHPVVY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00599004;
90% Identity: iTF_00579408; iTF_00475346;
80% Identity: -