Dame009062.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila americana
Gene Symbol
-
Assembly
GCA_018152915.1
Location
JAECXQ010000569.1:9069583-9076543[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 18 1.6e-05 0.00092 19.3 2.1 1 23 156 178 156 178 0.97
2 18 5.2e-06 0.0003 20.8 0.4 1 23 184 206 184 206 0.97
3 18 0.00076 0.044 14.0 0.9 1 23 212 234 212 234 0.95
4 18 1.1e-05 0.00064 19.7 3.1 1 23 240 262 240 262 0.97
5 18 2.5e-05 0.0015 18.6 4.7 1 23 268 290 268 290 0.99
6 18 4.5e-05 0.0027 17.8 5.7 1 23 296 318 296 318 0.97
7 18 2.2e-07 1.3e-05 25.1 4.3 1 23 324 346 324 346 0.98
8 18 8e-08 4.7e-06 26.5 2.4 1 23 352 374 352 374 0.97
9 18 4.7e-05 0.0027 17.8 6.7 1 23 381 403 381 403 0.97
10 18 8.1e-05 0.0047 17.0 6.5 1 23 409 431 409 431 0.98
11 18 7.2e-06 0.00042 20.3 4.5 1 23 437 459 437 459 0.98
12 18 5.2e-06 0.00031 20.8 8.1 1 23 465 487 465 487 0.98
13 18 4.3e-06 0.00025 21.0 7.6 1 23 493 515 493 515 0.97
14 18 4.8e-07 2.8e-05 24.0 7.7 1 23 521 543 521 543 0.98
15 18 0.00015 0.0087 16.2 9.5 1 23 549 572 549 572 0.95
16 18 5.3e-05 0.0031 17.6 0.9 1 23 578 600 578 600 0.98
17 18 0.00058 0.034 14.3 3.4 1 23 610 632 610 632 0.97
18 18 6.6e-06 0.00038 20.4 1.6 1 23 638 661 638 661 0.96

Sequence Information

Coding Sequence
ATGCAGCACGTGAGCGCTGCCAGTTCGGCACCTTCGGTGGTTTCAGCACCGGTGGTGACCACTGGCGGTGGCACCACCATCACTTTGGGCGGACCGCCGCCATTGCCCGGCAGCAAATCAGATCATAAAGAGGACGGCGGCAAGCCGCCACACGGCATTGAAATGTATAAAGTGAACATTGAGGATATATCACAGTTATTTACGTATCACGAGGTCTTTGGCAAAATCCATGGCGATGTGGTGAATCATGTGGCGGCGGGCAGCGCCACGGTGACCACGACTAGCTCTGGCAGCAACGGGGGGAATGGGGGCCAGAACAACAACAACAACAACAATAACAACAACTCGACAACGACGACGACGGGTGAGTTGCTAATGCCGAAAATGGAGGGCGGCATTCATGGCGTCGATGGGCAATCGAGCGTTGCGTTGGCGCCGGATGGCACGCCCATAGCGACTGGTACGCATGTCTGCGACATTTGTGGCAAAATGTTCCAGTTTCGCTATCAGCTGATTGTGCACCGTCGCTACCACAGCGAGCGCAAGCCGTTTATGTGTCAGGTATGCGGTCAGGGTTTTACCACATCGCAGGATTTGACCCGGCATGGGAAGATCCACATTGGCGGTCCCATGTTCACTTGCATTGTGTGCTTCAATGTGTTTGCCAATAATACAAGTCTGGAGCGCCATATGAAACGGCATTCAACGGACAAGCCATTCGCCTGCACCATTTGCCAAAAGACTTTCGCACGCAAAGAGCATCTGGACAATCATTTTCGTTCGCATACGGGCGAAACACCGTTCCGTTGTCAGTACTGCGCCAAGACGTTTACGCGCAAGGAGCACATGGTTAATCATGTGCGCAAACACACGGGTGAGACGCCACATCGTTGCGATATTTGTAAGAAGTCCTTCACGCGCAAGGAACACTATGTTAACCACTACATGTGGCACACTGGTCAAACACCGCATCAGTGCGATGTCTGCGGCAAGAAATACACGCGCAAGGAGCACCTAGCCAACCATATGCGCTCCCACACCAACGAGACGCCGTTTCGTTGCGAAATCTGCGGCAAGAGCTTTAGTCGCAAGGAGCATTTCACCAATCACATACTCTGGCATACAGCAGGCGAGACGCCGCATCGGTGCGACTTCTGCTCCAAGACGTTTACGCGCAAGGAGCATTTGTTAAATCACGTGCGCCAGCACACGGGAGAGTCGCCGCATCGCTGCTCCTACTGCATGAAGACGTTTACGCGCAAGGAGCATCTGGTGAATCATATACGCCAGCACACGGGTGAGACACCGTTCAAGTGCACGTACTGCACGAAAGCGTTCACACGCAAAGATCACATGGTTAATCATGTACGGCAACATACAGGCGAATCGCCGCACAAGTGCACATACTGCACCAAGACGTTTACGCGCAAGGAGCACCTCACGAATCATGTGCGACAGCACACGGGCGATTCGCCGCATCGTTGCAGCTACTGCAAGAAGACCTTCACCCGCAAGGAGCATTTGACGAATCATGTACGCCTGCACACTGGAGATTCGCCGCACAAATGCGAATACTGCCAGAAGACGTTCACGCGCAAGGAGCATCTCAATAACCATATGCGCCAGCACTCGAGCGACAATCCCCATTGTTGCAATGTGTGCAACAAGCCCTTCACACGCAAGGAGCATTTGATTAATCATATGTCCCGTTGCCACACCGGCGATCGTCCTTTCACCTGCGAGACGTGCGGTAAATCGTTCCCCCTCAAGGGTAATCTGCTGTTCCATCAGCGCAGCCACACCAAGGGCCAGGAGTGCGAGCGTCCGTTTGCCTGCGAGAAGTGCCCCAAGAATTTCATATGCAAAGGTCACTTGGTCTCGCACATGCGCTCCCATTCGGGCGAGAAACCGCACGCGTGCACACTGTGCAGCAAGGCTTTCGTCGAGCGCGGCAATTTGAAGCGCCACATGAAGATGAATCACCCGGATGCTATGATGCCGCCACCACCCGTGCATCCGCATCCGCAAATACCGGCTGGTGTGCTGACCCAAGTCAAGCAGGAAGTGAAACCGATCATAATTCCCCATCACTCGGCGACGACCACGATGCACACCATTCAGCAGATAACAGCGGGCGCTGCAGCGGCTGGCGCCGGTGCCCAACATCCGGTGGTTTACTAA
Protein Sequence
MQHVSAASSAPSVVSAPVVTTGGGTTITLGGPPPLPGSKSDHKEDGGKPPHGIEMYKVNIEDISQLFTYHEVFGKIHGDVVNHVAAGSATVTTTSSGSNGGNGGQNNNNNNNNNNSTTTTTGELLMPKMEGGIHGVDGQSSVALAPDGTPIATGTHVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHGKIHIGGPMFTCIVCFNVFANNTSLERHMKRHSTDKPFACTICQKTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRKHTGETPHRCDICKKSFTRKEHYVNHYMWHTGQTPHQCDVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFSRKEHFTNHILWHTAGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCSYCMKTFTRKEHLVNHIRQHTGETPFKCTYCTKAFTRKDHMVNHVRQHTGESPHKCTYCTKTFTRKEHLTNHVRQHTGDSPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRKEHLINHMSRCHTGDRPFTCETCGKSFPLKGNLLFHQRSHTKGQECERPFACEKCPKNFICKGHLVSHMRSHSGEKPHACTLCSKAFVERGNLKRHMKMNHPDAMMPPPPVHPHPQIPAGVLTQVKQEVKPIIIPHHSATTTMHTIQQITAGAAAAGAGAQHPVVY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00599004;
90% Identity
iTF_00541885;
80% Identity
-