Dlut013507.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila lutescens
Gene Symbol
-
Assembly
GCA_037075285.1
Location
JBAMCF010000743.1:1320343-1323243[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 8.3 6.7e+02 1.4 0.4 1 20 93 112 93 114 0.90
2 13 0.0044 0.36 11.7 3.9 2 23 190 212 189 212 0.95
3 13 4.1e-06 0.00033 21.2 5.5 2 23 219 241 218 241 0.96
4 13 0.011 0.88 10.4 9.0 2 23 473 494 473 494 0.97
5 13 2e-06 0.00016 22.2 2.9 1 23 500 523 500 523 0.95
6 13 0.0017 0.13 13.0 0.5 1 23 528 551 528 551 0.93
7 13 6.5e-05 0.0052 17.4 5.5 1 23 569 591 569 591 0.96
8 13 8.5e-05 0.0069 17.1 0.7 1 23 596 618 596 618 0.98
9 13 3.4e-05 0.0027 18.3 1.7 1 23 624 646 624 646 0.95
10 13 0.00012 0.0097 16.6 0.7 1 23 652 674 652 674 0.98
11 13 3.5e-07 2.8e-05 24.6 2.7 3 23 682 702 681 702 0.99
12 13 2.6e-08 2.1e-06 28.1 1.1 1 23 708 730 708 730 0.99
13 13 0.39 32 5.5 3.4 1 19 735 753 735 758 0.89

Sequence Information

Coding Sequence
ATGGCAACGCACCAGCCGCACCCGCAGCTGGAGCCGGCTTCGGGCCAGGAGCAGGAGTCGGCCAGTGAGCCGGCGGGCAGCAAGTTGGTGCTCCTCAACGCCCTGGACACCGTGGACGCGCAGCGCGTCTGTCGCGTTTGCCTGAAGGACGCCTCGCTGGACGGGGAGGTGCACTTCATCTTCAACGAGGCGCCCGTCGAGGAGGACGCCAATCTGGCCCGCATCCTGGACGAGTGCACCCAGCACCAGTGTCAGCGGCACGACGGGATGCCCCCGCATATGTGCGGCACTTGCGTGGAGGCGGCCCGCCACGCCTATCGCTTCAAGAGGCACGCGGAGCGCTCCTACTGCTCGCTGGTGGCCCTGCTGGGTCGCTCGCCCCAGCTGAAGGCCCACGGAACGGAGGCGGCCAGCCAGACGGACCAGGTGGCCCTAATGCCCTGCGAGATGTGCCACGACCAGTTCCTGAACAGCCTGGAGCTCCGACTGCACCGCAACCAGGTGCACAGGACGAACAAGGAGGGCACAACCGGCACCGGGACGGATGGCCAGCCGGCCGAGGAGCTCAAGTGCAAGTTCTGCCCGCAGCATTTCCCGCATCTCCGACAGCTGCAAAGCCATTTGGCGCGCAGCCACGAGCAGACCGCCCGGCTGCAGTGCGCCCATTGCCAGCGCACCTTCAGCCGGCGGGATCACCTGCTGCGGCACATGCGCAACCAGCACCGGGACATGGAGGAGGACCTGCTGCGCACCTGGCCGCCGGCGGACGAGAGCACCATGCACAGCGACGGCGGCGATGAGCTGGTCTCCGCCGAGGTGCTGCTGaacgaggaggacgacgacgacgaccgtGACGGAGTCGGCGAAGCCTTCCAGTGCAATACGAATCCCATTTCCAgcaacgaggaggaggacgaagaGGCCAATGTGGCCAATCAGACGCTGTGGCTGCACATCAAGCCGGAGCCCTGCCTGGAGGCGGAAGAAGTCGACCTGGCCATGCAACTGAAGCTCGAGAAGAAGCGTCGGCGGCGAGAGAAGGCGGAAGCTCAGGCCGATGGCTCCATTGAACGGGCTGTGAAGGATGAACCCATTGCCATTGGCGACGCTCAGTTCAGCATTAAGGAGGAGAGCCACCTTGTGGGCAGCGAGGACGAGGCACCAATGGGAGTGGAGGACTTTATGAAGCTCCATGTCAGCGGAGAACTGACGCTCAGTGACGAGGATCGGTTCGATGATTTCGTGGACGAGGATAGCGACCTGGATGACGatgaggacgacgacgaggacggTGGCGAGGACGAAGATGGAGAATTCCGGCTCAAGCAGGAGCCGCTGGACGGCGAGAAACCGCCGAAGAAGTCCAAATCCGGCAGGCGTCGGCGCCGCAACAAGGGCGAGCCGAATCCCGAAAACCGCTGCGAAGTGTGCCAGCGCACCTTCTCGCGCCACTGCCACCTGCTGCGCCACAAGCTGTCGCATTTGGAGAAGAAGCCCCACAACTGTCCGCACTGCCCCAAGGCGTTCGCGCGCAGCGACCACCTCAAGGCGCATGTGCAGAGCCTGCACAGCAACAAGGAGCACAAGTGTGCGCTCTGCGAGGCCGCCTTTTCGCGACTGGACGCCTTGGAGCGACACAAGGTCAGCAAGCACAACGGCGAAGGCCTGGAGCCGGGCAGCGAACTGAAGCTACAGCTGGCGGAGCACACGTGCGAGTACTGCTCCAAGCGCTTCTCCAGCAAGACCTACCTGCGCAAGCACACCCTGCTGCACACCGACTTCCTTTACGCCTGCAAGACCTGCGAGGAGACATTCCGCGAGCGAGCGCAGCTTAGGGAGCACGAAAAAACGCACACCGGACAGCGCAACTTCCTCTGCTGCATCTGCGGCGACAGTTTCGCCCGGAACGACTACCTCCGCGTGCACATGCGGCGCCACAACGGTGAGAAGCCCTACAAGTGCCGCTTCTGTGCCAAGGCCTTTCCCCGCGCCACCGATCTCAAGGTCCACGAGCGTTACCACACGGGCACCAAGCCGAATCTGTGCAATACTTGCGGCAAGAGCTTCCATCGGGCCTACAACCTGACCATCCACATGCGCACCCACACCGGCGAGCGGCCGTACAAGTGCGACCAGTGCCCCAAGAGCTTCACGCAGAGCAACGACCTCAAGGCGCACATCCGGCGGCATACGGGCGAGCGGTACAAGTGTCCGCACTGcgacgcctacttcctgcagcTGTACAACATGCGCAACCACTGTTTGAGCGCCCACAACAAGCACATCGAGACGAAGACGGGTCGTCTTCAGCGTACAGGCCTGCTGGACGATGGTGGCCAGTCGCATCTGACCACTGTGGTCATGCCGCCGGCACGGTATCCACATGAGCTGGATCCCCAGATGGCCGCGGCAGCAGCTGCCGGGGCTGAGAGCTCCTCCTCGACCACCGTCATACACTCACCGGGGACGTACAATGCCCCATCCACCGGACTGGCGCCGGGATCAGCGGCCGCTGCTCCAGCCAGCACCCTCGATGGAGCCAGCTTCGCCCCCACGACGGTGAATGCGTCGGCTCCATTTGGCGCCTTTAACTTTCCGCCGGTCGTAATGGCGCATCTCATGTACAACCACGGAGGAGGCAGCCAGCACAGCCAGAGCGGAAGCGACACGGGCAAATAG
Protein Sequence
MATHQPHPQLEPASGQEQESASEPAGSKLVLLNALDTVDAQRVCRVCLKDASLDGEVHFIFNEAPVEEDANLARILDECTQHQCQRHDGMPPHMCGTCVEAARHAYRFKRHAERSYCSLVALLGRSPQLKAHGTEAASQTDQVALMPCEMCHDQFLNSLELRLHRNQVHRTNKEGTTGTGTDGQPAEELKCKFCPQHFPHLRQLQSHLARSHEQTARLQCAHCQRTFSRRDHLLRHMRNQHRDMEEDLLRTWPPADESTMHSDGGDELVSAEVLLNEEDDDDDRDGVGEAFQCNTNPISSNEEEDEEANVANQTLWLHIKPEPCLEAEEVDLAMQLKLEKKRRRREKAEAQADGSIERAVKDEPIAIGDAQFSIKEESHLVGSEDEAPMGVEDFMKLHVSGELTLSDEDRFDDFVDEDSDLDDDEDDDEDGGEDEDGEFRLKQEPLDGEKPPKKSKSGRRRRRNKGEPNPENRCEVCQRTFSRHCHLLRHKLSHLEKKPHNCPHCPKAFARSDHLKAHVQSLHSNKEHKCALCEAAFSRLDALERHKVSKHNGEGLEPGSELKLQLAEHTCEYCSKRFSSKTYLRKHTLLHTDFLYACKTCEETFRERAQLREHEKTHTGQRNFLCCICGDSFARNDYLRVHMRRHNGEKPYKCRFCAKAFPRATDLKVHERYHTGTKPNLCNTCGKSFHRAYNLTIHMRTHTGERPYKCDQCPKSFTQSNDLKAHIRRHTGERYKCPHCDAYFLQLYNMRNHCLSAHNKHIETKTGRLQRTGLLDDGGQSHLTTVVMPPARYPHELDPQMAAAAAAGAESSSSTTVIHSPGTYNAPSTGLAPGSAAAAPASTLDGASFAPTTVNASAPFGAFNFPPVVMAHLMYNHGGGSQHSQSGSDTGK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00504826;
90% Identity
iTF_00548213; iTF_00581683; iTF_00578692; iTF_00604987; iTF_00605723;
80% Identity
-