Dmim004943.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila mimetica
Gene Symbol
-
Assembly
GCA_037075245.1
Location
JBAMCH010000005.1:17364530-17367467[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.0018 0.14 12.8 4.7 1 23 202 225 202 225 0.97
2 12 4.3e-06 0.00033 21.1 4.9 2 23 232 254 231 254 0.96
3 12 0.011 0.82 10.4 9.0 2 23 489 510 489 510 0.97
4 12 1.9e-06 0.00015 22.2 2.9 1 23 516 539 516 539 0.95
5 12 0.0016 0.13 13.0 0.5 1 23 544 567 544 567 0.93
6 12 6.3e-05 0.0049 17.4 5.5 1 23 585 607 585 607 0.96
7 12 8.4e-05 0.0064 17.0 0.7 1 23 612 634 612 634 0.98
8 12 3.3e-05 0.0026 18.3 1.7 1 23 640 662 640 662 0.95
9 12 7.7e-06 0.00059 20.3 0.9 1 23 668 690 668 690 0.98
10 12 3.5e-07 2.7e-05 24.5 2.7 3 23 698 718 697 718 0.99
11 12 2.5e-08 1.9e-06 28.1 1.1 1 23 724 746 724 746 0.99
12 12 0.38 30 5.5 3.4 1 19 751 769 751 774 0.89

Sequence Information

Coding Sequence
ATGGCAACGCACCAGCCGCCCCCGCAACTGGAGCCGGTTTCgggccaggagcaggagcaggagcaggataCGTCGGCCAACGAGCCGGTGGGCAGCAAGTTGGTGCTCCAACTCAGCGCCCTGGACACCGTGGATGCGCAGCGCGTCTGTCGCGTTTGCCTGAAGGACGCCTCGCTGGACGGGGAGCAGCTGCACTTCATCTTCAGCGAGTTGCCCGTCGAGGAGGACGCCAATCTGGCCCGCATCCTGGACGAGTGCACGCAGCACCAGTGCCAGCGGCACGACGGGATGCCCCCGCATATGTGCGGCTCCTGCGTGGAGGCCGCCCGCCATGCCTACCGCTTCAAGAGGCATGCGGAGCGCTCCTACTGCTCGCTGGTGGCCCTGCTCGGGCGATCGCCCCAGCTGAAGACGCGCGGCACGGAGGCGGCCAGCCAGACGGATCAGGTGGCCCTGATGCCCTGCGAGATGTGCCACGATCAGTTCCTCAACAGCCTGGAGCTCCGTCTGCATCGCAATCAGGTGCACCGGACGACCAAGGAGGGCACAACGGCAGCAACGGGCGGTGGAACCGGGACGGATGGCCAGCCGCCGGCCGAGGAGTTCAAGTGCAAGTTCTGCCCGCAGCATTTCCCGCATCTACGACAGCTGCAGAGTCATTTGGCGCGCAGCCACGAGCAGACCGCCCGGCTGGAGTGCGCCCACTGCCAGCGCACCTTTAGTCGGCGGGATCACTTGCTGCGGCACATGCGCAACCAGCACCGGGACATGGAGGAGGACCTGCTGCGCAACTGGCCGCCGGCGGACGAGAGCACCATGCACAGCGATGGCGGCGATGAGCTGGTCTCCGCCGAGGTGCTGCTGAACGAGgtggacgacgacgacgacgacgatggccATGACGGGATCGGCGAAGGCTTCCAGTGCAATACGAATCCCATTTCCAgcaacgacgaggaggaggaggaggacgaggtgCCCAGTGTGGCCAATCAAACGCTGTGGCTGCACATCAAGCCGGAGCCCTGcctggaggcggaggaggtcGACCTGGCCATGCAGCTGAAGCTCGAGAAGAAGCGTCGGCGGCGGGAGAAGGCGGCGGAAGCTCAAGCCGCTGGCTCCCTGGATCGGGCTGTGAAGGATGAACCCATTGCCATTGGCGACGCTCAGTTCAGCATTAAGGAGGAGAGCCAGCTTGTGGGCAGCGAGGACGAGGCACCAATGGGTGTGGAGGACTTCATGAAGCTGCACGTTAGCGGCGAGCTGACGCTCAGCGATGAGGATCGCTTCGATGAGTTCGTGGACGAGGATAGCGACCTCGATGACGatgaggacgacgacgaggacgaagaTGGAGAATTCCGGCTTAAGCAGGAGCCATTGGACGGCGAGAAGCCGCCGAAGAAGTCCAAGTCCGGCAGGCGTCGACGGCGCAACAAGGGCGAGCCCAATCCCGAGAACCGCTGCGAAGTGTGCCAGCGCACCTTCTCGCGCCACTGCCACCTGCTGCGCCACAAGCTGTCGCATCTGGAGAAGAAGCCCCACAACTGTCCGCACTGCCCCAAGGCTTTCGCGCGCAGCGACCACCTGAAGGCGCATGTGCAGAGCCTGCACAGCAACAAGGAGCACAAGTGTGCGCTCTGCGAGGCGGCCTTCTCCCGACTGGACGCCCTGGAGCGGCACAAGGTTAGCAAGCACAACGGCGAGGGCCTGGAGCCGGGCAGCGAACTGAAGCTCCAGCTGGCGGAGCACACGTGCGAGTACTGCTCCAAGCGCTTCTCCAGCAAGACCTACCTGCGCAAGCACACGCTGCTGCACACCGACTTCCTGTACGCCTGCAAGACCTGCGAGGAGACATTCCGCGAACGAGCGCAGCTGAGGGAGCACGAGAAAACGCACACCGGACAGCGCAACTTCCTGTGCTGCATCTGCGGCGACAGCTTCGCCCGGAACGACTACCTCCGCGTGCACATGCGGCGCCACAATGGCGAGAAGCCCTACAAGTGCCGCTTCTGTGACAAGGCCTTTCCCCGCGCCACCGATCTCAAGGTCCACGAGCGTTACCACACGGGCACCAAGCCGAATCTGTGCAACACCTGCGGCAAGAGCTTCCACCGGGCCTACAATCTGACCATCCACATGCGCACGCACACCGGCGAGCGGCCGTACAAGTGCGATCAGTGCCCCAAGAGCTTCACGCAGAGCAACGACCTCAAGGCGCACATCCGGCGGCATACGGGCGAGCGGTACAAGTGTCCGCACTGCGACGCCTACTTCCTGCAGCTGTACAACATGCGCAATCACTGCTTGAGCGCCCACAACAAGCACATCGAGACGAAGACGGGTCGTTTGCAGCGGACGGGACTGCTGGACGATGGGGGACAGTCGCATCTGACCACGGTGGTCATGCCGCCGGCCAGGTATCCACACGAATTGGATCCCCAGATGGCGGCGGCTGCAGCTGCCGCCGGCGCTGAGAACTCATCCTCGGCCACCGTCAGCCACTCGCCGGGAACGTACAGTGCTGCATCCGCTGGACTGCCGGCGGGATCGGTGTCCGCTGCTGTGGCCAGTAATCTTGATGGAGCCAGCTTCGCGCCCACGGCGGTGAATgcggcgacggcggcggcggcggctccaTTTGGCACCTTTAACTTTCCGCCAGCCGTTATGGCGCATCTCATGTACAACCACGGAGGCAGCAGCCAGCACAGCCAGAGTGGCAGTGAAACGGGCAAATAG
Protein Sequence
MATHQPPPQLEPVSGQEQEQEQDTSANEPVGSKLVLQLSALDTVDAQRVCRVCLKDASLDGEQLHFIFSELPVEEDANLARILDECTQHQCQRHDGMPPHMCGSCVEAARHAYRFKRHAERSYCSLVALLGRSPQLKTRGTEAASQTDQVALMPCEMCHDQFLNSLELRLHRNQVHRTTKEGTTAATGGGTGTDGQPPAEEFKCKFCPQHFPHLRQLQSHLARSHEQTARLECAHCQRTFSRRDHLLRHMRNQHRDMEEDLLRNWPPADESTMHSDGGDELVSAEVLLNEVDDDDDDDGHDGIGEGFQCNTNPISSNDEEEEEDEVPSVANQTLWLHIKPEPCLEAEEVDLAMQLKLEKKRRRREKAAEAQAAGSLDRAVKDEPIAIGDAQFSIKEESQLVGSEDEAPMGVEDFMKLHVSGELTLSDEDRFDEFVDEDSDLDDDEDDDEDEDGEFRLKQEPLDGEKPPKKSKSGRRRRRNKGEPNPENRCEVCQRTFSRHCHLLRHKLSHLEKKPHNCPHCPKAFARSDHLKAHVQSLHSNKEHKCALCEAAFSRLDALERHKVSKHNGEGLEPGSELKLQLAEHTCEYCSKRFSSKTYLRKHTLLHTDFLYACKTCEETFRERAQLREHEKTHTGQRNFLCCICGDSFARNDYLRVHMRRHNGEKPYKCRFCDKAFPRATDLKVHERYHTGTKPNLCNTCGKSFHRAYNLTIHMRTHTGERPYKCDQCPKSFTQSNDLKAHIRRHTGERYKCPHCDAYFLQLYNMRNHCLSAHNKHIETKTGRLQRTGLLDDGGQSHLTTVVMPPARYPHELDPQMAAAAAAAGAENSSSATVSHSPGTYSAASAGLPAGSVSAAVASNLDGASFAPTAVNAATAAAAAPFGTFNFPPAVMAHLMYNHGGSSQHSQSGSETGK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00504826;
90% Identity
iTF_00536918;
80% Identity
-