Dlim008345.1
Basic Information
- Insect
- Drosophila limbata
- Gene Symbol
- -
- Assembly
- GCA_963924055.1
- Location
- OZ001351.1:8400510-8403900[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.0046 0.46 11.6 1.0 2 23 143 165 142 165 0.90 2 12 1.1e-06 0.00012 23.0 2.1 2 23 179 201 178 201 0.97 3 12 0.0012 0.12 13.4 8.6 2 23 483 504 483 504 0.97 4 12 5.7e-06 0.00058 20.8 1.8 2 23 511 533 510 533 0.95 5 12 0.00028 0.028 15.5 0.5 1 23 538 561 538 561 0.96 6 12 3e-05 0.003 18.5 5.2 1 23 579 601 579 601 0.97 7 12 0.00013 0.014 16.5 1.6 1 23 606 628 606 628 0.98 8 12 3.5e-05 0.0035 18.3 1.7 1 23 634 656 634 656 0.95 9 12 2.5e-05 0.0025 18.8 0.7 1 23 662 684 662 684 0.98 10 12 3.6e-07 3.7e-05 24.5 2.7 3 23 692 712 691 712 0.99 11 12 5.8e-08 5.9e-06 27.1 1.8 1 23 718 740 718 740 0.99 12 12 1.6 1.7e+02 3.6 5.2 1 19 745 763 745 768 0.88
Sequence Information
- Coding Sequence
- ATGCCGGACACATTCAGCGAATTCGATGCGGAGCGCGTCTGTCGCGTTTGCCTGCGCGAAGTGGGCGATTTCTACTTTATCTACGATGAGGCGCCCGTGGAGCAGGGCGCAAACATTGCCCAAATACTAAATGAGTGCACGCGCTACACCTGCGAGCGATTCGACAAGATGCCCCATCATATGTGCGACACGTGCATTAAGGCCGCCTGCCAAGCGTATCGCTTCAAGCGAGATGCCGAAAAGGCCTATCGCTCCCTGGTGTCCATTTTGGGACAGACGCCTTCGGCGAAGCCAAACAGCAGCGATGTTTGCACACAGACTGAACAGCTACCGATGCTGCCGTGCGGCATTTGCAATGATGAGTTTCTCAACATTGTTGAGCTGCGTCTGCATCGCAATCAGGAGCACAAATATATTGAGGAACTCAAGTGCAAATTGTGCGATGCTAAATTCGAACAATTCCGACAATTGCGCAATCATCTGGTCGAGAAGCACGATCAGCAAACGACATCAGCATTGTTGCAACGTCGCGTCGAATGCCGCGAATGTAGACGCGCCTTCAGTCGACGTGATCATCTGCTTCGTCATATGCGCACAGTGCACAAGTCGGATAAACAGCGCCGGACGCTGTCCGACGACCAAGAGCTAGAGGTAGAGGAGGAGGATACAAGTTGGCAACCTGTAGACGAGGCAACCATGCACAGTGGCGATGAACTGGAATCAGCTGGCGTTTTACTCAATGCCACCCAATGTTCCGATGATGAGGAGAACGACAATAGCGAGAGTCTCTATCAAAGCCACACGAATCCCATATCAAGCAACGAGGAGGCTGACGACGATGAGGCCGACGCGGAGGCTAAGCAATCCCTTTGGCTGCACATTAAACCAGAGCCAGAAGCCGAGCCAGAGCCACATTGTCCGGCTCCAATTGAGGCGCAAGTGAAGCGCGAGAAGCGTCGAAGAAAAGCAAAGATGCACACAGACGATGAGGCGGAGAAAGAACAGAAGGTGGAAAGTGAAGAGAGCAAGAAAAGTGCACTGGCAACAGCAGAAGTTAAGGAGGAGCCATTGGCAGAGCCACAAGTGTCCATTAAACAGGAGCGACAACGCGTTGATAGCGTTAATGTGGATGCAGTGGATGAACTCGAGCTGAAAACCACAACAGCGGATAAGTTACACAGCTCCGATGAGGCGGAGGATGAGTTGGAGGACGATGAGGAAGAATTTGGCAATGATTCCAATGACAGCGACTTGGATTACGTGGACGATGACGATGGCGAAGATGAACCTGAAAGACCGGCTGTAGCCAAGGATAAGGCGAAGCTGCCAAAAGCAGTACAAGTGGAAATTGTCCGGGAATATTTACAGAAACCGTCGACAGTTAAgcaacgtcgtcgtcgtcgcaatAAACAGACTGATGCGGACTCAAATACGAATCCCGAGAATCGTTGTGAAATCTGTCAGCGAACTTTCTCCCGACATTGTCATTTGTTGCGCCACCAATTGTCGCATCTGGAGAAGAAGCCGCTCAGCTGTCCGCACTGCTCGAAGGGATTTGCACGTAGCGATCATTTAAAGGCGCATGTCCAGAGTCTGCATGGCAACAAAGAGCACAAGTGTGTGCTATGTGAAGCGGCCTTCACCCGACCCGACGCTCTCGAGCGGCACAAGCTGAGCAAACACAATGGCCAAGGCCTCGATCCAAACAGCGAGCTCAAGCTGCAACTGAATGAACACACATGTGAATACTGCTCCAAGCGATTCTCCAGCAAGACATATCTGCGCAAGCACACACTCATCCACACGGAATTCCTCTACGCCTGCAAAAGCTGCGACGAGACCTTCAAGGAGCGTCAACAGCTGCGCAGCCATGAGAAGACGCACACGGGACAGCGGAACTTTCTTTGTTGCATATGCGGCGACAGTTTTGCCCGCAACGATTATCTGCGCGTCCACATGCGCAGGCACAATGGAGAGAAGCCCTACAAGTGCCGTTACTGCGTCAAGGCATTCCCGCGTGCCACAGATCTCAAGGTGCACGAGCGGTATCACACTGGCACCAAACCGAATCTGTGCAACACGTGCGGCAAGAGTTTCCATCGCGCCTACAATCTGACCATCCACATGCGAACACACACGGGCGAGCGTCCGTACAAGTGCGATCAGTGCCAGAAGAGCTTCAGCCAGAGCAACGATCTGAAGGCGCACATTAGACGCCACACGGGCGAGCGCTACAAGTGTCCACATTGTGATGCATACTTCCTGCAACTATATCACATGCGCAACCATTGCCTCAGCGCTCACAACAAGCATATTGAAACAAAAACGGGCAGACTACAACGCACTGGTCTCCTGGATGAACCGATTCTCTCGCATCTCACCACGGTGGTGATGCCACCAACGCGCTTCCAGCCGGATGCAACTGtaaccacaaccacaaccgCGGCGGCATCTGCAACAATTGCCACACCAATTCTACATTCTCCTGTCACCTACAACACGGCATCGCCGGCATCTGCTACTGTGCCCGTCACCTTGCCTGTCCAGGATGCAGCCGGATTTGTGGGCTCTGCGAATaatgcaacagcaacgacaacgacatcgGCGCCCTTTGGGGCATTCAACATAGCGCCCGTTGTGATGGCCCATCTCATGTACAACCACGGAGGCAACAGTCAACCGAGCAATGCCAGCGGCAGCGAAACGGGAAAATAG
- Protein Sequence
- MPDTFSEFDAERVCRVCLREVGDFYFIYDEAPVEQGANIAQILNECTRYTCERFDKMPHHMCDTCIKAACQAYRFKRDAEKAYRSLVSILGQTPSAKPNSSDVCTQTEQLPMLPCGICNDEFLNIVELRLHRNQEHKYIEELKCKLCDAKFEQFRQLRNHLVEKHDQQTTSALLQRRVECRECRRAFSRRDHLLRHMRTVHKSDKQRRTLSDDQELEVEEEDTSWQPVDEATMHSGDELESAGVLLNATQCSDDEENDNSESLYQSHTNPISSNEEADDDEADAEAKQSLWLHIKPEPEAEPEPHCPAPIEAQVKREKRRRKAKMHTDDEAEKEQKVESEESKKSALATAEVKEEPLAEPQVSIKQERQRVDSVNVDAVDELELKTTTADKLHSSDEAEDELEDDEEEFGNDSNDSDLDYVDDDDGEDEPERPAVAKDKAKLPKAVQVEIVREYLQKPSTVKQRRRRRNKQTDADSNTNPENRCEICQRTFSRHCHLLRHQLSHLEKKPLSCPHCSKGFARSDHLKAHVQSLHGNKEHKCVLCEAAFTRPDALERHKLSKHNGQGLDPNSELKLQLNEHTCEYCSKRFSSKTYLRKHTLIHTEFLYACKSCDETFKERQQLRSHEKTHTGQRNFLCCICGDSFARNDYLRVHMRRHNGEKPYKCRYCVKAFPRATDLKVHERYHTGTKPNLCNTCGKSFHRAYNLTIHMRTHTGERPYKCDQCQKSFSQSNDLKAHIRRHTGERYKCPHCDAYFLQLYHMRNHCLSAHNKHIETKTGRLQRTGLLDEPILSHLTTVVMPPTRFQPDATVTTTTTAAASATIATPILHSPVTYNTASPASATVPVTLPVQDAAGFVGSANNATATTTTSAPFGAFNIAPVVMAHLMYNHGGNSQPSNASGSETGK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00585358; iTF_00601971; iTF_00575747; iTF_00528969; iTF_00507027; iTF_00523095; iTF_00586103; iTF_00519324; iTF_00510685; iTF_00558064; iTF_00608588; iTF_00537653;
- 90% Identity
- iTF_00585358; iTF_00601971; iTF_00586103;
- 80% Identity
- -