Dneo015217.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila neotestacea
Gene Symbol
-
Assembly
GCA_035044365.1
Location
JAWNMD010000607.1:227809-230984[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.0067 0.52 11.1 2.3 2 23 143 165 142 165 0.90
2 12 5.2e-06 0.0004 20.9 2.6 2 23 179 201 178 201 0.97
3 12 0.0012 0.091 13.4 8.6 2 23 472 493 472 493 0.97
4 12 9.8e-07 7.5e-05 23.1 0.4 2 23 500 522 499 522 0.96
5 12 0.00027 0.021 15.5 0.5 1 23 527 550 527 550 0.96
6 12 1.3e-05 0.00097 19.7 4.1 1 23 568 590 568 590 0.97
7 12 0.00013 0.0099 16.5 1.6 1 23 595 617 595 617 0.98
8 12 3.4e-05 0.0026 18.3 1.7 1 23 623 645 623 645 0.95
9 12 0.00034 0.026 15.2 0.7 1 23 651 673 651 673 0.98
10 12 3.5e-07 2.7e-05 24.6 2.7 3 23 681 701 680 701 0.99
11 12 2.2e-08 1.7e-06 28.3 0.8 1 23 707 729 707 729 0.99
12 12 1.6 1.2e+02 3.6 5.2 1 19 734 752 734 757 0.88

Sequence Information

Coding Sequence
ATGCCTGACACATTTAGCGAATTCGATGCAGAACGCGTCTGTCGCGTTTGCCTTCGCGAAGTGGGCGATTTCTACTTTATTTACGATGAGGCGCCCGTGGAGCAGGGCGCAAATATTGCCCAGATACTCAATGAATGTACGCGTTACACCTGCGAGAGGTTCGATAAGATGCCCCACCACATGTGCGACACCTGCATTAAAGCCGCCTGCCAAGCATATCGCTTTAAAAGAGATGCAGAAAAGTCCTATCGCTCCTTGGTGGCAATTCTGGGAAGGAATCCAATAACAAAGCCCAACAGCAGCGACATTGCCACACAGACTGAACAGTTGCCGATGCTGCCATGCGGCATTTGCAATGATGAATTCCTTAATACCATGGAACTGCGTATTCATCGAAATGAACAGCACAAATATATCGAAGATCTTAAGTGTAAACTGTGTGATACAGAATTCGAGCACTTCCGTCAATTGCGCAATCATCTTGTCGAGAAGCATGACCAAGAGACATCATCACCTTTGTTGCGACGCCGTGTTGAGTGCCGTGAATGCAAAAGCTCCTTCAGTCGACGTGATCATCTGCTTCGTCATATGCGCACTGTCCACAAGTCGAATAAAAAGCGCGGGACGCTATCCGAGGAACAGGAGTCAAATATAACCTGGCCCCCAATCGACGAGACAACAATGCACAGTGGCGATGAACTGGAATCAGCTGCAGTTCTGCTCAATGCCCACTGTACAGATGATGAGGACAACGATAATAGCGAAAGTGTCTATCAAAGCCATACGAATCCCATATCAAGCAACGAGGAGgctgacgacgacgacgttgaTGTTGAGGCTAAGCAATCTTTATGGCTACACATTAAACCAGAACCCGAGCCCGAAGCAGAGCCAGAGGTAGAACATTCTTCAACTCCAGCTTCGGCGCATGTGAAGCGCGAGAAGCGTAGAAGAAAAGCAAGGATCAATACGGACAAcgaggaggaagaggaaagTGAAAATAAACGGAAAAGTGGGACCAAAAGTGAACCGGCGACAACAGCAGTTAAGGAGGAACCACTGGCAGATCAACAATTGTCCATTAAGCAGGAACGACAACGCATTGATAGCGTTAATGTGGTTGAGCAGGAATGTTACAAACTGGATGAGAATATATTGCACAGCTCggaggatgaggatgacgatgatTTTGCCAATGATAGCAATGATAGTGACCTGGATTACATTgctgacgatgatgatgacaacgaAACAGAGACCAGAGCTCCTAAGACCGAAGATAAACCAAAGCTGTCACAAGCTGCACAGGTGGAAATCATCCGGGAATATCTACATAAACCAACGACGGGCAAAcagcgtcgtcgtcgtcgcaaTAAACAAACTGATGGAGAATCAAATTCCAATCCTGAGAATCGTTGTGAAATCTGTCAACGCACCTTCTCCCGCCATTGTCATTTGTTGCGCCACCAATTGTCGCATCTGGAAAAGAAGCCGCTCAGTTGTCCAATTTGTTCCAAGGGCTTTGCACGTAGCGATCATTTGAAGGCACACATACAAAGTCTCCATGGCAACAAGGAGCATAAGTGTGTCCTTTGTGAAGCTGCCTTCACACGTCCAGATGCTCTAGAGCGACACAAGCTGAGTAAACACAATGGCGAGGGACTCGACGCGAATAGTGAactcaaattgcaattgagcGAGCATACATGTGAATATTGCTCCAAGAGATTCTCCAGCAAGGCGTATCTACGTAAACACACTCTGATCCATACGGATTTCCTCTACGCCTGCAAAAGCTGCGACGAGACCTTCAAGGAGCGTCAACAACTGCGAAGCCACGAGAAAACGCACACTGGCCAGCGGAACTTCCTCTGTTGCATATGCGGAGATAGTTTTGCACGCAACGATTATCTCCGTGTCCACATGCGGCGACACAATGGAGAGAAGCCCTACAAGTGCCGTTACTGCATCAAGGCATTCCCGCGTGCCACAGATCTTAAGGTGCACGAGCGTTATCACACTGGCACCAAACCGAATTTGTGCAACACATGTGGCAAGAGCTTTCATCGTGCCTATAATCTCACCATTCACATGCGCACACACACGGGCGAGCGTCCCTATCAGTGTGATCAGTGCCCCAAGAGCTTTAGCCAAAGCAATGACCTTAAGGCTCACATAAGACGGCACACGGGCGAGCGTTACAAGTGTCCACATTGCGATGCCTACTTTCTGCAGCTTTATCACATGCGCAACCATTGCCTCAGTGCCCACAACAAGCATATTGAAACAAAGACGGGAAGATTGCAACGCACTGGACTCCTGGATGAGCCAACGCATTCACATCTAACCACGGTCGTAATGCCACCAACACGTTTTCAAACCGATGTCACGACCCTtgtgacagcaacaacacaactacctgttgcaacaacagcggcaactgcaacaattgcCACACCAATTCAACATTCTCCTGTCACCTATAACACAACATCGCCACTATCTGTAACTGTCCCTGTCACGTTGCCTGCCCAGAATGCAACTGGATTTGTGGCTGCTGCAAACAATGCtgtcacagcaacagcaacagcagcggctcCCTTTGGGGCATTCAACATAACGCCCGTTGTGATGGCGCATCTCATGTATAATCACGGTGGCAACAGTCAACAGAGCAATGCCAGTGGCAGCGAGACGGGCAAATAG
Protein Sequence
MPDTFSEFDAERVCRVCLREVGDFYFIYDEAPVEQGANIAQILNECTRYTCERFDKMPHHMCDTCIKAACQAYRFKRDAEKSYRSLVAILGRNPITKPNSSDIATQTEQLPMLPCGICNDEFLNTMELRIHRNEQHKYIEDLKCKLCDTEFEHFRQLRNHLVEKHDQETSSPLLRRRVECRECKSSFSRRDHLLRHMRTVHKSNKKRGTLSEEQESNITWPPIDETTMHSGDELESAAVLLNAHCTDDEDNDNSESVYQSHTNPISSNEEADDDDVDVEAKQSLWLHIKPEPEPEAEPEVEHSSTPASAHVKREKRRRKARINTDNEEEEESENKRKSGTKSEPATTAVKEEPLADQQLSIKQERQRIDSVNVVEQECYKLDENILHSSEDEDDDDFANDSNDSDLDYIADDDDDNETETRAPKTEDKPKLSQAAQVEIIREYLHKPTTGKQRRRRRNKQTDGESNSNPENRCEICQRTFSRHCHLLRHQLSHLEKKPLSCPICSKGFARSDHLKAHIQSLHGNKEHKCVLCEAAFTRPDALERHKLSKHNGEGLDANSELKLQLSEHTCEYCSKRFSSKAYLRKHTLIHTDFLYACKSCDETFKERQQLRSHEKTHTGQRNFLCCICGDSFARNDYLRVHMRRHNGEKPYKCRYCIKAFPRATDLKVHERYHTGTKPNLCNTCGKSFHRAYNLTIHMRTHTGERPYQCDQCPKSFSQSNDLKAHIRRHTGERYKCPHCDAYFLQLYHMRNHCLSAHNKHIETKTGRLQRTGLLDEPTHSHLTTVVMPPTRFQTDVTTLVTATTQLPVATTAATATIATPIQHSPVTYNTTSPLSVTVPVTLPAQNATGFVAAANNAVTATATAAAPFGAFNITPVVMAHLMYNHGGNSQQSNASGSETGK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00533986;
90% Identity
iTF_00608588;
80% Identity
-