Dmac006743.1
Basic Information
- Insect
- Drosophila macrospina
- Gene Symbol
- -
- Assembly
- GCA_035042075.1
- Location
- JAWNLW010000340.1:4852256-4856044[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 9.3 6e+02 1.2 0.2 2 23 114 136 113 136 0.87 2 13 0.0062 0.41 11.1 0.5 2 23 143 165 142 165 0.90 3 13 6.8e-07 4.4e-05 23.6 2.2 2 23 179 201 178 201 0.96 4 13 0.006 0.39 11.2 9.0 2 23 472 493 472 493 0.97 5 13 1.9e-06 0.00012 22.2 2.9 1 23 499 522 499 522 0.95 6 13 0.00026 0.017 15.5 0.5 1 23 527 550 527 550 0.96 7 13 6.3e-05 0.0041 17.4 5.5 1 23 568 590 568 590 0.96 8 13 0.00013 0.0082 16.5 1.6 1 23 595 617 595 617 0.98 9 13 3.3e-05 0.0022 18.3 1.7 1 23 623 645 623 645 0.95 10 13 0.00033 0.021 15.2 0.7 1 23 651 673 651 673 0.98 11 13 3.4e-07 2.2e-05 24.6 2.7 3 23 681 701 680 701 0.99 12 13 2.3e-08 1.5e-06 28.2 1.0 1 23 707 729 707 729 0.99 13 13 1.5 1e+02 3.6 5.2 1 19 734 752 734 757 0.88
Sequence Information
- Coding Sequence
- ATGCCTGACACATACAGCGAATTCGATGCGGAGCGAGTCTGTCGCGTTTGCCTGCGCGAAGTGGGTGATTTCTACTTCATTTACGATGAGGCGCCCGTGGAGCAGGGCGCAAACATTGCCCAGATACTCAATGAATGCACGCGTTACACCTGCGAGCGGTTCGACAAGATGCCCCATCATATGTGCGATACCTGCATCAAGGCCGCCTGCCAGGCGTATCGTTTCAAGCGAGACGCTGAGAAGGCCTATCGCTCCTTGGTGGCCATCCTGGGACGGACTCCGGCCACCAAGCCGAACAGCAATGATGTGTGCACCCAGACTGAACAGTTGCCGATGCTGCCGTGCGGCATTTGCAATGATAAATTTCTGAACATACTTGAATTGCGTGTGCATCGCAATCGACAGCACAAATTTATCGAGGaactcaaatgcaaattgtgcgaTGCACAATTCGAACAATTCCGCCAGTTGCGCAATCATCTTGTTGAGGAGCACGATCAACAGACAACATCACCATTGCTACGCCGACACCTGGAGTGCCGTGAGTGCAATCGTGCCTTCAGCCGACGTGATCATCTGCTTCGTCATATACGAACTGTGCACAAGGTGAATAAACAGCGCGGGACGCTGACCGAGGACCAAGAGTCGGATACGAACTGGCCACCTGTCGATGAGACAACCATGCAAAGCGGCGATGAACTGGAATCAGCTGCCGTTTTACTCAATGCCCAATGTTCTGATGATGAAGACAACGACAATATCGAGAGTGTCTATCAATGCCATACGAATCCCATATCAAGCAACGAGGAGGCTGACGATGAAGAAGCCGATGCCGAGGCTAAACAATCACTGTGGCTGCACATTAAACCAGAGCCAGAACCCGAGCCAGAGCTACAGCATTCTCCGGCTCTAATTGAGACTCACCTGAAGCGCGAGAAGCGTAGAAAAAAAACTAAGATGCCCACGGACAATGAAGAAGATGAGAGTGAAGACAAGCGGAAAAGTGCAGCCAAATGTGAACTGGCAACAACAGTAGTTAAGGAGGAACCCCTGGCAGAGCAACCAGTAGCGATCAAGCAGGAACAACAGCGCGTTGATAGCGTTAATgtggatgaggaggaggattATGAGCTGGATGCCACAGCAGAGGATATGTTAAACAGCACAGATGAGGCGGAGGAAGAGGATGAGGAAGATTTTGGCAATGAGGAGAGCGACATGGACTACATAGACGAAGACGACGGCGAAGATGAGAACGAACCAGAGGCAGCTACTCAAACCACAAATAAATCGAAGCTACCACAAGCGGCTCAAGTGGAAATCGTGCGGGAATATCTACAGAAGCCCTTGGCGGGCAAACAGCGTCGTCGACGtcgcaataaacaaaatgatgcACAACCAAATCCGGAGAATCGTTGTGAAATCTGTCAACGCACGTTCTCCCGTCATTGCCATCTGTTGCGCCACAAATTGTCGCATCTGGAGAAGAAACCGCACAACTGTCCACATTGTCCCAAGGCATTTGCACGCAGCGATCATTTGAAGGCACATGTGCAGAGTCTGCATGGCAACAAGGAGCACAAATGTGTACTATGTGAAGCTGCCTTCACACGTCCCGATGCTCTGGAGCGGCACAAGCTGAGCAAGCACAATGGCGAAGGTCTTGATGCGAGCAGCGAGCTGAAGCTGCAGATGAGCGAACACACATGCGAATATTGCTCCAAGAGATTCTCCAGCAAGACGTATCTGCGCAAGCACACGCTGCTCCACACGGAGTTCCTATACGCCTGCAAAAGTTGTGACGAGACCTTCAAGGAGCGTCAACAGCTGCGCAGCCATGAGAAGACGCACACCGGGCAGCGCAACTTCCTCTGTTGCATATGCGGAGATAGCTTTGCTCGCAACGATTATCTGCGCGTGCACATGCGACGGCACAATGGAGAGAAGCCATACAAGTGCCGTTACTGCATCAAGGCATTCCCGCGTGCCACAGATCTCAAGGTGCACGAGCGCTATCATACGGGCACCAAACCGAATCTGTGCAACACGTGTGGCAAGAGCTTTCATCGCGCCTACAATCTCACCATTCACATGCGCACGCACACGGGCGAGCGTCCCTACAAGTGCGATCAGTGCCCCAAGAGCTTCAGCCAGAGCAATGATCTGAAGGCGCACATAAGACGCCACACGGGAGAACGCTACAAGTGTCCGCATTGTGATGCCTACTTCCTGCAACTTTATCACATGCGCAACCATTGCCTCAGTGCCCACAACAAGCACATTGAGACGAAAACGGGACGCTTGCAACGCACTGGACTCCTGGATGAGCCAACGCACTCGCATCTCACCACGGTTGTTATGCCGCCAGCCCGTTTCCAGGCCGATgcaactgtaacaacaacaacaacaataacaacaactcaactGCCTAATGCAACAACTGCGGCACCTGTTAcaattgccacgcccattatACATTCTCCCGTCACCTACAACACGGCATCCCCCGTATCTGTCACTGTGCCCGTCACGTTGCCTGTCCAAGATGCCACGGGATTTGTGGGTGCGGCAAATAGTGCGTccgcaacggcaacggcgccGTTTGGGGCGTTCAACATAACGCCCGTTGTGATGGCCCATCTCATGTACAACCATGGAGGTAACAGTCAACAGAGCAATGCCAGCGGCAGCGAGACGGGCAAATAG
- Protein Sequence
- MPDTYSEFDAERVCRVCLREVGDFYFIYDEAPVEQGANIAQILNECTRYTCERFDKMPHHMCDTCIKAACQAYRFKRDAEKAYRSLVAILGRTPATKPNSNDVCTQTEQLPMLPCGICNDKFLNILELRVHRNRQHKFIEELKCKLCDAQFEQFRQLRNHLVEEHDQQTTSPLLRRHLECRECNRAFSRRDHLLRHIRTVHKVNKQRGTLTEDQESDTNWPPVDETTMQSGDELESAAVLLNAQCSDDEDNDNIESVYQCHTNPISSNEEADDEEADAEAKQSLWLHIKPEPEPEPELQHSPALIETHLKREKRRKKTKMPTDNEEDESEDKRKSAAKCELATTVVKEEPLAEQPVAIKQEQQRVDSVNVDEEEDYELDATAEDMLNSTDEAEEEDEEDFGNEESDMDYIDEDDGEDENEPEAATQTTNKSKLPQAAQVEIVREYLQKPLAGKQRRRRRNKQNDAQPNPENRCEICQRTFSRHCHLLRHKLSHLEKKPHNCPHCPKAFARSDHLKAHVQSLHGNKEHKCVLCEAAFTRPDALERHKLSKHNGEGLDASSELKLQMSEHTCEYCSKRFSSKTYLRKHTLLHTEFLYACKSCDETFKERQQLRSHEKTHTGQRNFLCCICGDSFARNDYLRVHMRRHNGEKPYKCRYCIKAFPRATDLKVHERYHTGTKPNLCNTCGKSFHRAYNLTIHMRTHTGERPYKCDQCPKSFSQSNDLKAHIRRHTGERYKCPHCDAYFLQLYHMRNHCLSAHNKHIETKTGRLQRTGLLDEPTHSHLTTVVMPPARFQADATVTTTTTITTTQLPNATTAAPVTIATPIIHSPVTYNTASPVSVTVPVTLPVQDATGFVGAANSASATATAPFGAFNITPVVMAHLMYNHGGNSQQSNASGSETGK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00533986;
- 90% Identity
- iTF_00510685;
- 80% Identity
- -