Dleo013768.1
Basic Information
- Insect
- Drosophila leontia
- Gene Symbol
- -
- Assembly
- GCA_008042735.1
- Location
- VNKB01011814.1:4003-9253[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 8 0.00048 0.041 14.4 2.0 1 23 716 738 716 738 0.98 2 8 8.1e-05 0.007 16.8 1.4 1 23 770 792 770 792 0.97 3 8 0.11 9.7 7.0 0.4 1 19 800 817 800 823 0.81 4 8 0.0015 0.13 12.9 0.0 3 23 830 851 829 851 0.96 5 8 0.00016 0.013 16.0 3.5 1 23 857 879 857 879 0.97 6 8 0.01 0.9 10.2 0.2 1 23 886 909 886 909 0.95 7 8 0.0002 0.017 15.6 2.2 2 20 916 934 915 937 0.91 8 8 0.052 4.5 8.0 9.1 1 23 943 966 943 966 0.96
Sequence Information
- Coding Sequence
- gTTGATCAGTCACTAAATCTACTGGACAGCCTCAACACGGCATTGCGGTGCGATGCTATTCAATTCTTGCTGCAGACTCTCAAGTGCAAATATCCGGAGGCCTGCGACCAAGTCGTCAGGAATCTGTTCAGTCACATAGCTGCAGCCAATGACAGCGGcggaggtggcggcggcggggctcagcagcaggagctagCGAGGAcgaagcagctgcagctgctgctgaccgCCAAGAAGGAGAAGACGGAACCGGGAACGGGAGGGGAGGCGAAGATCAAGCGCGAgaacgacgacgatgaggcTGGATCGACGGATCTGAACCAGAACTTTGAGAAGATCCTCTGCAAGGAGGAGTTCCTGTGcctcgaggaggaggaagaggattTCCTTGACGATGCTGACACCCAAAACTCGTCTTCCCTGCAATTCAATGCTGGTAACAATGTGGACGCCCTGGCCCTAGGCCCCGGCGACCCGCTGGACCTGATCCACACGGGGAATTCCCTGTTGGTCAAGCGGAAGTATGCTGCTACCTTCGAGGACGAGAACCAGCTGGCCGAGGATGCTAACAGCAATAGTAGCGACGGCAAGCTGGTTAAGAGGAAGCGCACCAATAACATGCACCTGACCGTGACGAGTGTGCGGCGGAAAGAGGCACGCTCCCGTCTGGGAGAGGGGTACATCTTCCACGAGGACAGCCAGTACACGATGCGCTATCACCACAGCACCGGCGAGTTCAGTGAGCGGGCCTTCAAGGCCCAGTTCCGAGCTTTGCTGCGCATGGCGCTCAGCCAGCACCACAAGCCGTTCCTGCGGCAGTTCTACGAGAACTTTGTGGTAAACGGGCGCCTGTTGGGTACCACGCCCTCGGCGAGAGTGCTCAAGGAGCTGCGCGAGCAGCGGCTAGAGGAATGGCGTCGTCATCGGGAGCGCCGTCAGCTGGTCAGCATGATGAAGCAGAGTGAGCAGAAGTTAGAAGAGatccagcaggagcagcagcgggaggaagttcagcagcatcagctggaagagatgcagcagcagcagcagctggaagaGATTCAACGGCAGCATCAGTTGCCGGCCATCTCGTTTGGCGACTCCGAGTTGGAGTCGGAAACGGAATCGCAGCTGTCGTCGGCTGCTCAAGAGATTATGAAGTTTGAGGAGTTCATTGACGAGGGTGTAGGCGCGGGACGTCTGATTGATGGTCTGGAAATGGAGCTTGAGACCGATGACATGTTAGCTGGCGCCGGCAGTGTCCTGGACAGCGTGAACAGCGCTAGCgggcacagcagcaacagcagcagcagcgggagtGGGAGCGGCGCTAATGGGAATGGCATCAGCAGCGGGGTGATCCTGGAGAACAATAGTCATCATTCGCATCACCTaagtagcagcagcagcgcaaatATTGTGATCAACGGCCTTACGTCAAGCAATAgtatcagcaacaacaataataataataataacaacaataatggcAGCATGCATTGTCCGCAATTAACGCTGCAGACGCAGGATCAGGCGGGAGCGTCTTTGAAGCCGTCGCACCACTTGCCCATGTCCATGTCATTGGAACACAGGGATGCGAAGGGCAGCCAGGTCCTTGGCAATGCCAATGTGATCATGCCAAGCGGCAGCTCCGGTCACGCCAGCGAGATTCAGCTGCACCAGCAGCAAAACCACTACAACTCAAGCAATAATCCCCTAAGCATGATGGGTGGAATGAtgcaccaacagcagcagcagcagcagcagcagcatgtgAGCatgcaacaccaacaacagcatcagcaacatcaGATGATGCCGGGGCAGGGGTTTCCCCAGCATGGAACTTCCATGATGGTCAACCGTCAAATGCCCGCTCTGGCTGCTTTGTCCAATCTGGGCGACACTCCTCCTATCGGCAGCCAGTTAAACTCGTCCCTGGAGCTGGACGACAACGACCTGTCGGGCGACGAGGATGACGACGACCTGGAACATGATCTGGACGAGCTGGAAGCggccaagcagcagctgattgatggcggcagcagcagtagtacCTCCCTGCAGGCACCGCCATCGCAACACGGCAGCGGCAGTGGAGGCAGCGGAGGGCAGACGCCCGGCAGCAAGAAGAACAAGCCCAGCTACAATTGCCTGCTGTGTCCCAAGTCGTATCGCAAGAGAAAATCCCTGCTTGACCACTACAAGATGCATCCTGGTTTCTGTCACGATTGCGGACAGCCCAACGGAAATACGTTAGAGGAAGTAATCCTCCACAACAGGACGATGCATGTAAAGGAGTTTCCTTTCGTGTGCGAGACTTGCGGAGAGTCGTACTCGCGAAAGCAGCAGTTCCACGCCCACGTGGAGTCGCACAACAAGAAGGAAATCAAAACATTTCCCTGCGGAGAATGCGGGTTGAAATTTCCGCAGAAGAAGCTACAGCAGCACTTTGAGGAGACGGGCCACAAGGCCGACGGGGCCATTTGCGAGGTGTGCGGCGAGGAGTTTCAGTCGAAGAACGCCCTATACCAGCACATCATTCGCGTTCACAAGCGCGACAACTTTTTCGAGTGCCACATTTGCCATAACCGCTTCACGCTAAAGGCGAACCTGGAGCGTCACGTGCAGCTGCACACCGAGGTTAAACGGCCCTACGTGTGCGACCTGTGCGGCTCGTCCTACTACACATATCCCGCGCTCAAGGAGCACTATAGCAATGCCCATGTCGATGTCTCCGAGTGCAAGTGTACGCTGTGCGGCAAGCGCTTCGGATCGGCCAAGTCGCTCCAAAGGCACCTGCCATCGCACTCGGAGGAGCGTCCGCACTGTTGCAACTATTGCGATCAGACCTTCAAGTGGAAGACGCATCTGGTGCGCCACAAGCAGACGACGCACGGAAACGAGCCGCCGCCTCCTAAGAAGGGAAAGCAGCGCTTCCCCAAGGCAAACGAAGAAGCAGAAATGCCTTCCCTGCCGGATATGCCTGGACCGCCGCCTGTAAAGGCCAGCAAAAAGGCGGTGACGAGTAAGGCGAAAGCGCAAGCGGCAGTCGCCGCGGGAGGAACCTCCCAGttgcagcatcagcagaagGGCGTTGCAGCCACACCgacgccaccgccgccggtgTCCACGACACCGGGATGCATGCAACAAGATCAGTTTAATGCGGCCATggtcagcagcaacagctcgCAGTCCTCCACGGCGTCCACATCGCAGCATTCGGTGTCGACGAtacaacaacagcaacagcaattcCTGCAGCAACAGGCCTCTGACTCCTGGGGCAACATGAACTTTGGCAATCCACCAAACAACCAGCAAGTGGAGCTCAAGGATAACAAATTCTATATCCCTTACCACCCACACGGCctgcaggcgcagcagcagtcgccaTTGCATCCGCATCTGCTGCCACCGCCAGCGCCGCACGGAAGCGTCTATGACCGCACGGGAGTTGGCGTCGGTGTTGGAGTCGGAGTTGGCTATTCCATGCTGGGAGATGAGTCTAAGGCGGTGCTGCCGCCGATGATGGGCGGCATGATGCAGCAATTGCCACCGCATGGCCAGCAACCGGACTTAATATACTACCCAGTGAAGAACGATTGA
- Protein Sequence
- VDQSLNLLDSLNTALRCDAIQFLLQTLKCKYPEACDQVVRNLFSHIAAANDSGGGGGGGAQQQELARTKQLQLLLTAKKEKTEPGTGGEAKIKRENDDDEAGSTDLNQNFEKILCKEEFLCLEEEEEDFLDDADTQNSSSLQFNAGNNVDALALGPGDPLDLIHTGNSLLVKRKYAATFEDENQLAEDANSNSSDGKLVKRKRTNNMHLTVTSVRRKEARSRLGEGYIFHEDSQYTMRYHHSTGEFSERAFKAQFRALLRMALSQHHKPFLRQFYENFVVNGRLLGTTPSARVLKELREQRLEEWRRHRERRQLVSMMKQSEQKLEEIQQEQQREEVQQHQLEEMQQQQQLEEIQRQHQLPAISFGDSELESETESQLSSAAQEIMKFEEFIDEGVGAGRLIDGLEMELETDDMLAGAGSVLDSVNSASGHSSNSSSSGSGSGANGNGISSGVILENNSHHSHHLSSSSSANIVINGLTSSNSISNNNNNNNNNNNGSMHCPQLTLQTQDQAGASLKPSHHLPMSMSLEHRDAKGSQVLGNANVIMPSGSSGHASEIQLHQQQNHYNSSNNPLSMMGGMMHQQQQQQQQQHVSMQHQQQHQQHQMMPGQGFPQHGTSMMVNRQMPALAALSNLGDTPPIGSQLNSSLELDDNDLSGDEDDDDLEHDLDELEAAKQQLIDGGSSSSTSLQAPPSQHGSGSGGSGGQTPGSKKNKPSYNCLLCPKSYRKRKSLLDHYKMHPGFCHDCGQPNGNTLEEVILHNRTMHVKEFPFVCETCGESYSRKQQFHAHVESHNKKEIKTFPCGECGLKFPQKKLQQHFEETGHKADGAICEVCGEEFQSKNALYQHIIRVHKRDNFFECHICHNRFTLKANLERHVQLHTEVKRPYVCDLCGSSYYTYPALKEHYSNAHVDVSECKCTLCGKRFGSAKSLQRHLPSHSEERPHCCNYCDQTFKWKTHLVRHKQTTHGNEPPPPKKGKQRFPKANEEAEMPSLPDMPGPPPVKASKKAVTSKAKAQAAVAAGGTSQLQHQQKGVAATPTPPPPVSTTPGCMQQDQFNAAMVSSNSSQSSTASTSQHSVSTIQQQQQQFLQQQASDSWGNMNFGNPPNNQQVELKDNKFYIPYHPHGLQAQQQSPLHPHLLPPPAPHGSVYDRTGVGVGVGVGVGYSMLGDESKAVLPPMMGGMMQQLPPHGQQPDLIYYPVKND
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00480419; iTF_00531907; iTF_00491781; iTF_00613733; iTF_00488905; iTF_00607958; iTF_00485400; iTF_00524664; iTF_00483198; iTF_00594078;
- 90% Identity
- -
- 80% Identity
- -