Basic Information

Insect: Drosophila seguyi
Gene Symbol: -
Assembly: GCA_008042675.1
Location: VNJU01002916.1:205820-211501[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.00053 0.039 14.3 2.0 1 23 734 756 734 756 0.98

2 8 9e-05 0.0066 16.8 1.4 1 23 788 810 788 810 0.97

3 8 0.13 9.2 6.9 0.4 1 19 818 835 818 841 0.81

4 8 0.0017 0.12 12.8 0.0 3 23 848 869 847 869 0.96

5 8 0.00017 0.013 15.9 3.5 1 23 875 897 875 897 0.97

6 8 0.012 0.85 10.1 0.2 1 23 904 927 904 927 0.95

7 8 0.00022 0.016 15.5 2.2 2 20 934 952 933 955 0.91

8 8 0.058 4.2 7.9 9.1 1 23 961 984 961 984 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.00053	0.039	14.3	2.0	1	23	734	756	734	756	0.98
2	8	9e-05	0.0066	16.8	1.4	1	23	788	810	788	810	0.97
3	8	0.13	9.2	6.9	0.4	1	19	818	835	818	841	0.81
4	8	0.0017	0.12	12.8	0.0	3	23	848	869	847	869	0.96
5	8	0.00017	0.013	15.9	3.5	1	23	875	897	875	897	0.97
6	8	0.012	0.85	10.1	0.2	1	23	904	927	904	927	0.95
7	8	0.00022	0.016	15.5	2.2	2	20	934	952	933	955	0.91
8	8	0.058	4.2	7.9	9.1	1	23	961	984	961	984	0.96

Sequence Information

Coding Sequence: ATGGTCGGCTTGAAACGGAAGTTGGTTGATCAGTCACTAAATCTACTGGACAGCCTCAACACGGCATTGCGGTGCGATGCTATTCAATTCTTGCTGCAGACTCTTAAGTGCAAATATCCGGAGGCCTGCGACCAAGTCGTCAGGAATCTGTTCAGTCACATAGCTGCAGCCAATGACAGCGGCGGAGGTGGTGAGGGCGGCGGGgctcagcagcaggagctaGCGAGGAcaaagcagctgcagctgctgctgaccgccaagaaggagaagaaggaacCGGGAACGGGGGAGGAGGCGGAGATTAAGCGCGAGAACGATGACGATGAGGCTGGATCGACGGATCTGAACCAGAACTTTGAGAAGATCCTCTGCAAGGAGGAGTTCCTGTGcctcgaggaggaggaagaggactTCCTTGACGATGCTGACACCCAAAACTCGTCTTCCCTGCAGTTCAATGCTGGCAACAATGTAGACGCCCTGGCCCTAGGCCCCGGCGATCCGCTGGACCTCATCCATACGGGGAGTTCCCTGTTGGTCAAGCGGAAGTATGCTGCTACCTTTGAGGACGAGGACCAGCTGGCCGAGGATGCGAACAGCAATAGTAGCGACGGAAAGCTGGTCAAGAGGAAGCGCACCAACAACATGCACCTGACCGTGACGAGTGTGCGGCGGAAAGAGGCACGCTCCCGGCTGGGAGAAGGGTACATCTTCCACGAGGACAGCCAGTACACGATGCGCTATCACCACAGCACCGGCGAGTTCAGCGAGCGGGCCTTCAAGGCCCAGTTCCGGGCTTTGCTGCGCATGGCGCTTAGCCAGCACCACAAGCCGTTCCTGCGGCAGTTCTACGAGAACTTTGTGGTGAACGGGCGTCTGTTGGGTACCACGCCCTCGGCGCGAGTGCTCAAGGAGCTGCGAGAGCAGCGGTTAGAGGAGTGGCGCCGTCATCGGGAGCGCCGTCAGCTGGTCAGCATGATGAAGCAGAGTGAGGAGAAGTTGGAGGAAatccagcaggagcagcagcgggaggaaattcagcagcagcagcagcagcagctggatgagattcagcagcagcagcagcagcagcagctggaggagattCAACGGCAGCATCAGTTGCCGGCCATCTCGTTTGGCGACTCCGAGCTGGAGTCGGAAACGGAATCGCAGCTGTCGTCGGCTGCTCAAGAGATTATGAAGTTTGAGGAGTTCATTGACGAGGGTGTAGGCGCGGGACGTCTGATTGATGGtctggagatggagctggagaCCGATGACATGTTAGCTGGAGCCGGCAGTGTCCTGGACAGTGTGAACAGCGCCAGCGGACAcagtagcaacagcagcagcagcggggggagtgggagtggcGCTAATGGGAATGGCATCAGCAGCGGGGTGGTCCTGGAGAACAATAGTCATCATACGCATCACCTaagtagcagcagcagcgcaaatCTTGTGATCAACGGCCTTACGTCAAGCAATAGtatcagcaacaacaacaataataataataacaacaataatggcAGCCTGCATTGTCCGCAGTTAACGCTGCAGGCGCAGGATCAGGCGGGAGCGTCCTTAAAGCCGTCGCACCACCTGCCAATGTCCATGTCATTGGAGAACAGGGATGCAAAGGGCGGCCAGAACCTTGCCAATGCCAATGTGATCATGCCGAGCGGCAGCTCGGGTCACGCCAGCGAGATTCAGCTGCACCAGCAGCAAAACCACTACAACTCAAGCAATAATCCCCTAAGTATGATGGGTGGAATGAtgcaccaacagcagcagcagcagcatcagcagcagcagcacgtgGGCATGCAACATCAGCAAccgcatcagcagcatcagATGATGCAGGGACAGGGGTTTCCCCAGCATGGAACTTCCATGATGGTCAACCGTCAAATGCCCGCTCTGGCTGCCTTGTCGAACCTGGGCGACACTCCTCCTATCAGCAGCCAGTTAAACTCCTCCCTAGAGCTGGACGACAACGACCTGTCGCCCgatgaggatgatgacgaCCTGGAGCATGACCTGGACGAGCTGGAAGCGGCCAAGCAGCAGCTGATCGATGgcggtagcagcagcagcacctccCTGCAGGCGCCGCCATCGCAAcacggcagcggcagtggaGGCAGCGGTGGTCAGACACCCGGCAGCAAGAAGAACAAGCCCAGCTACAATTGCCTGCTCTGTCCCAAGTCTTACCGCAAGAGGAAGTCCCTGCTTGACCACTACAAGATGCATCCCGGTTTCTGTCACGATTGCGGACAGCCCAACGGAAATACGTTAGAGGAAGTAATCCTCCACAACAGGACGATGCATGTGAAGGAGTTTCCTTTCGTGTGCGAGACGTGCGGAGAGTCGTACTCGCGGAAGCAGCAGTTCCACGCCCACGTGGAGTCGCACAACAAGAAGGAAATCAAAACATTTCCGTGCGGCGAATGCGGGTTGAAATTCCCACAgaagaagctgcagcagcactTCGAGGAGACGGGCCACAAGGCCGACGGGGCCATTTGTGAGGTGTGCGGCGAGGAGTTCCAGTCGAAGAACGCCCTATACCAGCACATCATACGCGTTCACAAGCGCGACAACTTTTTCGAGTGCCACATTTGCCATAACCGCTTCACGCTAAAGGCGAACCTGGAGCGCCACGTGCAGCTGCACACCGAGGTTAAACGGCCGTACGTGTGCGACCTGTGCGGCTCGTCCTACTACACATATCCCGCGCTCAAGGAGCATTACAGCAATGCCCACGTCGACGTGTCCGAGTGCAAGTGCACGCTGTGCGGCAAGCGCTTCGGATCGGCCAAGTCGCTCCAAAGGCACTTGCCTTCGCACTCGGAGGAGCGTCCGCACTGTTGCAACTATTGCGATCAGACCTTCAAGTGGAAAACGCATCTAGTGCGCCACAAGCAGACGACGCACGGAAACGAGCCGCCGCCTCCCAAGAAGGGAAAGCAGCGCTTCCCCAAGGCGAACGAAGAAGCAGAAATGGCTTCCCTGCCGGATATGCCTGGACCGCCGCCTGTAAAGGCCAGCAAAAAGGCGGTGACGAGTAAAGCGAAAGCGCAAGCGACAGTCGCCGCTGGAGGGGCCTCCCagctgcagcatcagcagaagGGTGTTGCTGCTACGCcaacgccaccgccgccggtaTCCACGACTCCGGGTTGCATCCAACAAGATCAGTTTAATGCGGCCATGGTCAGCAGCAATAGCTCGCAGTCCTCCACGGCGTCCACATCGCAGCACTCGAGCCCCCATCCGCCGCACCCCTcgcagctgcaacagcagcaggcacagccGCACTTCAGCTCCCCCCACCATATGCCACCTatgcaccaccagcaccagctaatgatgcagcagcagcaccgccaCAACCAGCGGTCGCCGCTGCACCACCACCCAGCGGCCCagcaattgcagcagcagcatcaacaaccgTCGCATTCCCCCCAGCATGCGAGACTGCAGTCGCCACAACCTGCTCCAgtacaacaacagcaacagcaattcCTGCAGCAACAGGCCTCCGACTCCTGGGGCAACATGAACTTTGGCAATCCACCCAACAACCAGCAAGTGGAGCTCAAGGATAACAAATTCTATATCGTTGACTCGGCCGACGTTTACGACCGCACGGGAGTCGGCGTAGGCGTCGGAGTCGGAGTGGGCTATTCCATGCTGGGAGATGAATCAAAGGCGGTGCTGCCGCCAATGATGGGCGGGATGATGCAGCAATTGCCACCGCATGGCCAGCAACCGGACTTAATATACTACCCAGTGAAGAACGATTGA
Protein Sequence: MVGLKRKLVDQSLNLLDSLNTALRCDAIQFLLQTLKCKYPEACDQVVRNLFSHIAAANDSGGGGEGGGAQQQELARTKQLQLLLTAKKEKKEPGTGEEAEIKRENDDDEAGSTDLNQNFEKILCKEEFLCLEEEEEDFLDDADTQNSSSLQFNAGNNVDALALGPGDPLDLIHTGSSLLVKRKYAATFEDEDQLAEDANSNSSDGKLVKRKRTNNMHLTVTSVRRKEARSRLGEGYIFHEDSQYTMRYHHSTGEFSERAFKAQFRALLRMALSQHHKPFLRQFYENFVVNGRLLGTTPSARVLKELREQRLEEWRRHRERRQLVSMMKQSEEKLEEIQQEQQREEIQQQQQQQLDEIQQQQQQQQLEEIQRQHQLPAISFGDSELESETESQLSSAAQEIMKFEEFIDEGVGAGRLIDGLEMELETDDMLAGAGSVLDSVNSASGHSSNSSSSGGSGSGANGNGISSGVVLENNSHHTHHLSSSSSANLVINGLTSSNSISNNNNNNNNNNNGSLHCPQLTLQAQDQAGASLKPSHHLPMSMSLENRDAKGGQNLANANVIMPSGSSGHASEIQLHQQQNHYNSSNNPLSMMGGMMHQQQQQQHQQQQHVGMQHQQPHQQHQMMQGQGFPQHGTSMMVNRQMPALAALSNLGDTPPISSQLNSSLELDDNDLSPDEDDDDLEHDLDELEAAKQQLIDGGSSSSTSLQAPPSQHGSGSGGSGGQTPGSKKNKPSYNCLLCPKSYRKRKSLLDHYKMHPGFCHDCGQPNGNTLEEVILHNRTMHVKEFPFVCETCGESYSRKQQFHAHVESHNKKEIKTFPCGECGLKFPQKKLQQHFEETGHKADGAICEVCGEEFQSKNALYQHIIRVHKRDNFFECHICHNRFTLKANLERHVQLHTEVKRPYVCDLCGSSYYTYPALKEHYSNAHVDVSECKCTLCGKRFGSAKSLQRHLPSHSEERPHCCNYCDQTFKWKTHLVRHKQTTHGNEPPPPKKGKQRFPKANEEAEMASLPDMPGPPPVKASKKAVTSKAKAQATVAAGGASQLQHQQKGVAATPTPPPPVSTTPGCIQQDQFNAAMVSSNSSQSSTASTSQHSSPHPPHPSQLQQQQAQPHFSSPHHMPPMHHQHQLMMQQQHRHNQRSPLHHHPAAQQLQQQHQQPSHSPQHARLQSPQPAPVQQQQQQFLQQQASDSWGNMNFGNPPNNQQVELKDNKFYIVDSADVYDRTGVGVGVGVGVGYSMLGDESKAVLPPMMGGMMQQLPPHGQQPDLIYYPVKND

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00533319;
90% Identity: iTF_00491781;
80% Identity: -