Dleo018594.1
Basic Information
- Insect
- Drosophila leontia
- Gene Symbol
- lrrfip2
- Assembly
- GCA_008042735.1
- Location
- VNKB01002621.1:320-3885[-]
Transcription Factor Domain
- TF Family
- LRRFIP
- Domain
- LRRFIP domain
- PFAM
- PF09738
- TF Group
- Unclassified Structure
- Description
- LRRFIP1 is a transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'- AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA [1]. LRRFIP2 may function as activator of the canonical Wnt signalling pathway, in association with DVL3, upstream of CTNNB1/beta-catenin [2].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 2 3.4e-119 6.4e-115 383.6 18.0 1 299 29 324 29 325 0.95 2 2 0.041 7.7e+02 -0.8 3.4 218 241 351 374 327 398 0.51
Sequence Information
- Coding Sequence
- ATGGAAAGTGCCAGTACTGGTCGCCGAAGGAACAATATGCGGGTCAATGCGGAGGACAATGCACTAGATCAAATAACGAAAGAGGCGGAGGCCCGGCTTGCAGCGCGTCGACAAGCCCGAGCCGAGGCCCGCGAGATCCGTATGCGGGAGCTGGAGCGACAGCAAAAGGAGCTGGAGCTAACGGCCGACCGTGTATTCGATATGCAAAGCACCACTGGCGTCGGTGCAGGCGGTGGCGACACACTCCTCTCGACGCATCCCTCGCGGCTCGTCTATGGCGGCCTGGTAAATGTGGCCCGTGCATCGGTATCGCGGCGTAGCAGTGAGGACTCATTGGAGGATGACGGCCGAAGTTTTCGTGACTTCAAGCATGAGCTTAAAGACGTTGAGGAACGGTTTCGGAAGGCGATGATAACGAATGCCCAGCTGGACAACGATCGTGCTTCCCAGGCTTACGAGGTGAAACTGCTCAAGGATAAATGCGAAATAATGCAGGAATCGTTTGCCCAACTGCAGCGCGAATTTAAGGAGAAAATGCGCGACTGCAATGCCCTCAAACGGAACTTGGATCGGGCCAATCTCGAGCTGAAGCTCGTGCAGGGCCAGTTAAATGAGCGGGACTTGTTGATATCGGAGCAGGGCCTTCTGATTGTGGCTGTTGAGAACGAGGATGGCAGCGATGCCAAGCGGGCTCTGGTTAGTGTTGAGAACGCCAAGCTCTTGGCTTCCGTTCAGGGTTCTTTAGATGTTAGACTCAAAAAGTTCAGCGACGAAAAGAACAGATTGCTATCCGAGGTGCACAGTCTTCACGAACAGCTTGATGAATATAAAAGTGGAGGAATGGCTGGCGGTTCTGGCAGCTTTGCACATGGTTCTTTAGGCGAAGACGATGATTACGAGGCTCAAAGGGAGTCAAACAAAATCATTTCAGACTATAAATATAAGCTGCAAAAGGCTGAACAAGAAATCGCCAATTTACAATCGAGTTTAGCACGTTCAGAGACTCAAGTCATTCGATACAAAAGCACTGCGGAAGCCGCCGAAAAGTCAGAGGCTGAATTAAAAGTCGAGCGCCGCAAGCTACAACGTGAGCATCGGGAAATACTGGAGAGATTGGAGGAGGCGGAGACGGCCAATAACCATTTGCTAAAGCGTttggataaattaaaaaacgccAAGAGCGCCATTCTAAAAGACTTATGA
- Protein Sequence
- MESASTGRRRNNMRVNAEDNALDQITKEAEARLAARRQARAEAREIRMRELERQQKELELTADRVFDMQSTTGVGAGGGDTLLSTHPSRLVYGGLVNVARASVSRRSSEDSLEDDGRSFRDFKHELKDVEERFRKAMITNAQLDNDRASQAYEVKLLKDKCEIMQESFAQLQREFKEKMRDCNALKRNLDRANLELKLVQGQLNERDLLISEQGLLIVAVENEDGSDAKRALVSVENAKLLASVQGSLDVRLKKFSDEKNRLLSEVHSLHEQLDEYKSGGMAGGSGSFAHGSLGEDDDYEAQRESNKIISDYKYKLQKAEQEIANLQSSLARSETQVIRYKSTAEAAEKSEAELKVERRKLQREHREILERLEEAETANNHLLKRLDKLKNAKSAILKDL
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00336724;
- 90% Identity
- iTF_00606300;
- 80% Identity
- -