Dlac017189.2


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila lacicola
Gene Symbol
Trerf1
Assembly
GCA_035045355.1
Location
JAWNPB010000351.1:1042591-1056721[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 6 0.00015 0.01 16.4 0.2 2 23 352 373 351 373 0.97
2 6 4.6e-06 0.00031 21.1 1.3 1 23 379 401 379 401 0.98
3 6 0.00045 0.031 14.8 2.5 1 23 407 431 407 432 0.94
4 6 0.00076 0.052 14.1 0.8 2 23 687 708 686 708 0.97
5 6 0.0022 0.15 12.7 0.1 1 23 1821 1845 1821 1845 0.98
6 6 0.0001 0.0069 16.9 0.8 1 23 1965 1987 1965 1987 0.98

Sequence Information

Coding Sequence
ATGGCTGCCATAAATACGGTACCTAAGAGCATACACCTGCCATTGACGAATCTCAGCGCGCCTCGCGTGCTGATGTGCAGCGCATCTGTGGGCAGCGAGGGTTCCGTAACATTGCAACTAAGAGATGCGAATGCCTTGGAGGCAGCCGACAgcacgacaacagcaacaacagcaacaacagcaccagcaacaacaatagcaacaaatgcaatatCAACATCGTCATTAGGCAGCCAAGCGAATGGCGTCACAGTGCTTGAAACGTTCTCGGCATCGTCAGGAATAACGTCAGCGTTGGAAAATGCGTTGACCATTGGCTATCCGGATCCGGACATGTTAGCAGATGTCTTGGGCACCATACAGACCGCCTctcttaaaaacaaacaaattagcaGCAATACCAACATCtatagcaacaacagtaaGCGAAGTAGCTACATCAATGGTAGCAGCAGAAGAAACAGCAGCACTTCAACAACAATTCTGAACAACACCCTAGCAACAACGAGCTCTGGCGTACATCAGAACGGTCCCAATCAAATAACGATAACGCGACGCAGTGCCAGCAACAAGATCAGCGTGCAAACTGTAAGCGCATCCACAAATACAACCATTAGCAGCATTGGCGGCAGTAAGACCAACTACATAAAGAACTGTCTGATacggagcagcagctgcagcaacacgGCTACCAATGTCACGACGCTGGCACAGATtatgagcaacagcagcaccagcagcgcaGCCAGTTTACTCAGTcagcacaataataatagcaactgcagcaacagcagcaacttcaGCAACGCTTCATCCGTGGGCAGTAGCATTAGcattggcagcaacagcagcagcaacagcagcagtaacgacagcaacagcagcagcggtctCAGTTTAAGCTTCAAGAGCAACGGTCGAAATAATCCTGGTATTGTaactgcagcagcatccaCGAACACCACAGCCACCGGTATTGGCATTATCACCGTCGATAACGCACCCAGAAAGAGCCGACCCAAACTATCCTCACCGACTCGTCACGGACCCCAGCAGTGTCAGATTTGTAGcaagatctttggaaatgctTCGGCACTGGCCAAGCACAAACTGACGCACAGCGACGAGcggaaatatatttgtgcgcTCTGCTCGAAGGCATTCAAGCGGCAAGATCACTTAAACGGACACATGATGACGCATCGCAACAAGAAGCCTTACGAGTGTAAGGCAGATGGCTGCGGCAAATCATATTGCGATGCGCGCTCTCTCCGCCGTCATTCAGAGAATCACCATGGAGGCGTGGCAACGCTCAATAACAACTCACTCTCGCCCACAGCTAGCTCAAACTGCGGCAgcggaagcagcagcagcagcagcagcagtgtgggtgtgggtgtggccaACAGCTCACTAAGCCTTTCACCGGCTACAGCTAGTGGGGACGCCAGCTCGCCAGATGGGGCCACTTGCATCCGCACCTACATTTCCACAGGCAGCTCTGTGGTGGATGCTGCCACTGGCATTGCGCTGTCCGATGAACAGATCAAGGCTATGAATTTGCCCATTAAAACGGGAGTCACATTGCTGTCGCCCACCACTTCTACATCTTCAATTGCATCGACGTCAACATCCTCATCATGCTCAACATCTTGCGGTAGCGGCAGCTCCGTTCAAAATAGTTCGCCCACAATTACGCTTAGCGATGGCGCAACCTTAGAGGGCGATGGTCTCACGCGCGAGCAACTCGATCTGATAAGCAAGATCATGCAACAGACGAAGCAAACCAGTGCCCAGGTTACGGTCTCTTCGCCGAACAGCGTCAGCTCCTATAAGATCAATACAGAGACGGCGCCAGTCTCGGCACGTCCACGCACCTGGAACATGCAATTGCTTAATAACGCGCAAAATGTCACCGTAACCGTGGAGGATGGTACCGATATGGTTGCCTCCGCTTCAAGTTCACCCGACGAGGTCAAGGACGATGAATTGAACCAGCAGCTAGTGGCCGCTATTAATCCCCACCTGCTCAATATTGTTAAGATCGACAAGCCAGTTGAGTGCAATCTATGTCACCGCAAGTTCAAAAATATACCCGCTCTCAATGGGCACATGCGTCTGCATGGCGGTTACTTCAAAAAGGATCCGGAAACCAAGCGCAGCGAGAAAAAGGACTCCAATGGACCGCCCTTGCAGACTGCGAGCATAGGTGTCCGTGCCCTTATCGAGGAGAAGATCATTAGTAAGCGCAAGGACATCAATAAGGGCGCCTTCGTTGTGCCTGCACCACCCAGCAGCACCGCAAACAACGGAGGTGTTGGCGGCtgtagcaacaacagcaccagcCTACGCCGCTCCATAAGCGACTTAGAGAGCTTCTTAAATCCGAAGAGTAACACGAGCAGCCTGAGCCAGACACTAGCCACCAGCACCAGTACTACTACAGCGGTGCTGCCTGCGGCTACCACTATCAAGAGCAGCTCTGGGCTAAGTATACAGCAGATTGGGCTGCCGCAAAGTATTGAGATCTTCAGCGGAGGTCACAGACATCCCAAAACCCTTAATTTGGGCAGTGGTGCCAATACTATTACCATTACCACCAACAACGTGCCAACCACAACTACCATGAGCGCACTGACGGCTCTTAAGGGCGGCGGTAGCATCAGTGGCGTCACTAGCAATGCGGATTCCAAGGACTCGACGTTAATTGAGTTACTTAAGCGTGGAACGCGCATTGCCGTGGCCTCTAAGAAAACACAGCTACAGGCACAAAACAGTACAAATCTGATCTTAAGCAATGTTGGCGGCTCGGAGCTCACAACCATTAGCAGCAGTGTCCAGGCTGGTCGGCAGATTATCACCAAGAACAATCGCACAGTCATCATACCTTCTGATGTGCACGTGGTGTCCACTAAAAGCAAGTTAATTTCAAGCAACGCCCTCACAGCCAACGACAGCAATACAGCTTGTTCTGCGAGCAGTATATCATTGCCTGACGGGACTCCCCTCTCCCTGACCATTACGCCCAGCCAGGAGCGTATAGGTGTCGGAGAAGCAAGCAGCATAGCTGGTGGTGGGGGCGTTTACACGGTTACTTACACTAGCGATGCGGATGCATCCGATCTCTTCGACGACGCTGAGGTGTACAATGTATCGGACACGGAAATGCTACTGCAAACGGTGGATACTATGGAACTGCTCAACGATGACGAGGACGTGGTGCACAAAAGCGAACATTCCGAGGACTTTTCGATGCTTAGTGAGGCCGGCGATAATGTTCACACACAGCTGGTCAAGCTGGAGCCAGATCCTATACACAACAGCACAGCCAGCAGCCTCAATAAAACGACACCGTTGCCCACTTTTCAGCAATTTCATTCCAAGGAGATCATCATGCAGAACAGTTCTCAAATCCAGGCCATCGCCAACATGCGCGGAAGCAGCACCCTAGGAGTGCTCTCGTCGCCGTTGCATTCACCACTAGCCTACCCGACGCCACCCTCCAGCCACGAGAATGTGGCTCAATCCTCACCCTTCGTAGAGGATGCTGCGGGTCAGTTTGTGGATGCCAGTCACACGTTTTTTGGCGATAAAACAGACTTCTCACACGTCTATTTTAAAACAGACGAGAGCGATTCCATGCAACAGCTAAGTGATAATGACAACGAGAAAATACTCAAACTCAAGTCGGTGCTGGAAGAAAGCAGCTTCGATCCATCCATTAAAGTGGAAGATCTCTTAAACAGCACCGAGGACGATGCCGAATGCGACCTGCGGGAGTTTGCTGAGACGAATCTCTCATTTCTCGATGAGGATCAGGAGTTCCTAAATGACTCACGAAATGCTACCTCGCCTCTGTCCGAATCCTTCTTCACCAGTGGCATTGGATCTGCAGAGGATGTCAAACAGGTGCTACGTGAGGTGCTGCCCGATGAAAATATGCAACTGCAGCTAACTAGCGAGCAGCAGGGCGAGAACATCATTGATCTTTACTATTTACCGGGGCTGGGCCTGCAATCCCAAATGATGCCAAATTCTGATGATCCGCTTTTGTCCTCCTCCCCAAGAGAATTCGGTCAGCAACGACAGGTTGTCCAAACGACAACGTCTACGACATCAACCACACAACCTATCGAGCAGTTGCAATCTACCACTGTACTTTACGATCAACatcaactgcaacagcaactgcaacagcaactgcaactgcagccccagcagcaacagcaagagcaagagcaagagcaggagcaacatcagcagcaacagcagcagaaacagcaatcccagcagcagcaagagcaaatGCAATTGGCACAGCAACCTGCAATTCAATCTGAACAACCACAACAGGAGCAACAGACAGACTTTATGCTCACCAACTTTACTCCCGTGTCCTGTCAAACACAGTACCTAGATGCCAATCAGCAGACGATGATGCTGCAGCCACTGAATAGTTTGCTGCAGCCAATACTTtatggcagcaacagcacatcCAACGATAAACAAGCATTTACCTCGATGCTTAACTCGAATGCCGGTCAGGCAACTGAACTCGATGCTAGCCTGCTCTTTGCCTGCGGCGACAGCATCAAAAATAACTGCAGCAAACCTTTGCTTGCCGCATTACCCGCAGCAGTAGCTACACCAGTAGTTACTCCAACACCGAGCGTTTCCAATCTACAGCCGCTGTCCAACCAAACTAATTCCATATTAAAGCGTCGCCTGCGTTCAAATGGAGCACAGGATGTGCACAAGTTCTCTAAATTCCAAACACTTTCACCGCATCGCTCAAAGCTACGTAAGCCTTCGCGGACCCACTACACACCCGCACCAATTCTTAATCCAGATCGCAAAGGCACAGGACTCTATTGCAATGTGCGTAAACAGCTCGGCCAAGGAATGTTTGACGTCTTTGACGATGACTTTGGCGATCCTGTGGGCTTAGTTGATTTCTGCGATGAGTCCAAGGTGAATCTTGGTTCCACTTATCAAGCACAGATCCCACCCTGCAAATCGCCAGAAGAATCCACCAAGGAAACAATGAGCGCAGACCTACTTTGGGATCCAAGCGTACAGATAGACGAGAAGATACTAATGCGTTATATAGATCTCAGCAAATCTTCGGCCGTACCCTTGGGTAGCCATTCCGAAGAGGTAGCCCTTCAAACGTTGCTCGAGGCCAAAGGCAATTCAGCGGCGGCGGTGCTCACCTTGTTGCAAACGCAGTCTAGCGCATTCCAAATGAAATGGACTGCCTATGAGCTAGAACACTTTTTACGTGGCCTGGAGAAGCACGGGAAGGACTTTGGAAAAATTGCCAGCGAGTTACTTACGAAGACCTCGGGCGAGTGCGTtcaaatgtattatttttggaaaaaactATGTGTGGACTACAAGGTTTCTCACCTAAAGATGGAGCCAGTTCCTGCCAGCACTCCAACGGTGGAACAGAAGCCCTACGTCTGCGAGATTGCCGACTGCTCGGCGAGCTTCACCTCGAAAGCAGCTCTGCATGGTCATGTTCGCATACACGCTTATGGCAGAAATGCCAGCAACagtaatagcaacaacaacaaccagcatGCCACGGCAGTTagtgccaacaacaaccatacttgcaacaatagcagcaacaacaatagcaacaacgcATGCGCATCCCAGACTATTAGCCATAGCAATCAATGCAacagtgcaacaacaacaatcataaCGCACGCCAATGGCAATAACTCCACCCtcaacaacaatattatcagcaacaacattgcaCCAGGCTCTTCCATAAATACTGCAATGTTatcagtagcagcagcaacaggaacagcaTCGACAGCATCAaaagacagcagcaacagcaacaattccAATACAGCCAAGGAGAGTGAATTTCCCTGCAAGGTGTGCGGCAAAGTCTTCAATAAGGTCAAAAGCCGCAGTGCCCATATGAAAACGCATCGAGTACAAGAAGCGGAACAATCATCAAATTCCAAACAGCAATCTAACAATGGAAGTCTGTCTGCAGTAgcagtggcagttgcagcaTCAGCAGTACCATCGGCTCCCTCTGCAGTAACAGTTCTGGCCACAGCATCTTCTTAG
Protein Sequence
MAAINTVPKSIHLPLTNLSAPRVLMCSASVGSEGSVTLQLRDANALEAADSTTTATTATTAPATTIATNAISTSSLGSQANGVTVLETFSASSGITSALENALTIGYPDPDMLADVLGTIQTASLKNKQISSNTNIYSNNSKRSSYINGSSRRNSSTSTTILNNTLATTSSGVHQNGPNQITITRRSASNKISVQTVSASTNTTISSIGGSKTNYIKNCLIRSSSCSNTATNVTTLAQIMSNSSTSSAASLLSQHNNNSNCSNSSNFSNASSVGSSISIGSNSSSNSSSNDSNSSSGLSLSFKSNGRNNPGIVTAAASTNTTATGIGIITVDNAPRKSRPKLSSPTRHGPQQCQICSKIFGNASALAKHKLTHSDERKYICALCSKAFKRQDHLNGHMMTHRNKKPYECKADGCGKSYCDARSLRRHSENHHGGVATLNNNSLSPTASSNCGSGSSSSSSSSVGVGVANSSLSLSPATASGDASSPDGATCIRTYISTGSSVVDAATGIALSDEQIKAMNLPIKTGVTLLSPTTSTSSIASTSTSSSCSTSCGSGSSVQNSSPTITLSDGATLEGDGLTREQLDLISKIMQQTKQTSAQVTVSSPNSVSSYKINTETAPVSARPRTWNMQLLNNAQNVTVTVEDGTDMVASASSSPDEVKDDELNQQLVAAINPHLLNIVKIDKPVECNLCHRKFKNIPALNGHMRLHGGYFKKDPETKRSEKKDSNGPPLQTASIGVRALIEEKIISKRKDINKGAFVVPAPPSSTANNGGVGGCSNNSTSLRRSISDLESFLNPKSNTSSLSQTLATSTSTTTAVLPAATTIKSSSGLSIQQIGLPQSIEIFSGGHRHPKTLNLGSGANTITITTNNVPTTTTMSALTALKGGGSISGVTSNADSKDSTLIELLKRGTRIAVASKKTQLQAQNSTNLILSNVGGSELTTISSSVQAGRQIITKNNRTVIIPSDVHVVSTKSKLISSNALTANDSNTACSASSISLPDGTPLSLTITPSQERIGVGEASSIAGGGGVYTVTYTSDADASDLFDDAEVYNVSDTEMLLQTVDTMELLNDDEDVVHKSEHSEDFSMLSEAGDNVHTQLVKLEPDPIHNSTASSLNKTTPLPTFQQFHSKEIIMQNSSQIQAIANMRGSSTLGVLSSPLHSPLAYPTPPSSHENVAQSSPFVEDAAGQFVDASHTFFGDKTDFSHVYFKTDESDSMQQLSDNDNEKILKLKSVLEESSFDPSIKVEDLLNSTEDDAECDLREFAETNLSFLDEDQEFLNDSRNATSPLSESFFTSGIGSAEDVKQVLREVLPDENMQLQLTSEQQGENIIDLYYLPGLGLQSQMMPNSDDPLLSSSPREFGQQRQVVQTTTSTTSTTQPIEQLQSTTVLYDQHQLQQQLQQQLQLQPQQQQQEQEQEQEQHQQQQQQKQQSQQQQEQMQLAQQPAIQSEQPQQEQQTDFMLTNFTPVSCQTQYLDANQQTMMLQPLNSLLQPILYGSNSTSNDKQAFTSMLNSNAGQATELDASLLFACGDSIKNNCSKPLLAALPAAVATPVVTPTPSVSNLQPLSNQTNSILKRRLRSNGAQDVHKFSKFQTLSPHRSKLRKPSRTHYTPAPILNPDRKGTGLYCNVRKQLGQGMFDVFDDDFGDPVGLVDFCDESKVNLGSTYQAQIPPCKSPEESTKETMSADLLWDPSVQIDEKILMRYIDLSKSSAVPLGSHSEEVALQTLLEAKGNSAAAVLTLLQTQSSAFQMKWTAYELEHFLRGLEKHGKDFGKIASELLTKTSGECVQMYYFWKKLCVDYKVSHLKMEPVPASTPTVEQKPYVCEIADCSASFTSKAALHGHVRIHAYGRNASNSNSNNNNQHATAVSANNNHTCNNSSNNNSNNACASQTISHSNQCNSATTTIITHANGNNSTLNNNIISNNIAPGSSINTAMLSVAAATGTASTASKDSSNSNNSNTAKESEFPCKVCGKVFNKVKSRSAHMKTHRVQEAEQSSNSKQQSNNGSLSAVAVAVAASAVPSAPSAVTVLATASS