Basic Information

Insect: Drosophila virilis
Gene Symbol: Trerf1
Assembly: GCA_007989325.2
Location: CM017605.2:22922134-22934365[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 0.00012 0.0073 16.4 0.2 2 23 350 371 349 371 0.97

2 6 3.8e-06 0.00023 21.1 1.3 1 23 377 399 377 399 0.98

3 6 0.00038 0.023 14.8 2.5 1 23 405 429 405 430 0.94

4 6 0.00064 0.038 14.1 0.8 2 23 683 704 682 704 0.97

5 6 0.0018 0.11 12.7 0.1 1 23 1823 1847 1823 1847 0.98

6 6 8.5e-05 0.0051 16.9 0.8 1 23 1975 1997 1975 1997 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	0.00012	0.0073	16.4	0.2	2	23	350	371	349	371	0.97
2	6	3.8e-06	0.00023	21.1	1.3	1	23	377	399	377	399	0.98
3	6	0.00038	0.023	14.8	2.5	1	23	405	429	405	430	0.94
4	6	0.00064	0.038	14.1	0.8	2	23	683	704	682	704	0.97
5	6	0.0018	0.11	12.7	0.1	1	23	1823	1847	1823	1847	0.98
6	6	8.5e-05	0.0051	16.9	0.8	1	23	1975	1997	1975	1997	0.98

Sequence Information

Coding Sequence: ATGGCTGCCATAAATACGGTACCTAAGAGCATACACCTGCCATTGACGAATCTCAGCGCACCGCGCGTGCTGATGTGCAGCGCATCTGTCGGCAGCGAGGGTTCCGTAACACTGCAACTAAGAGATGCGAATGCCTTGGAGGCAGCCGACAgcacgacaacagcaacaacagcaacagcaacaacaatagcaacaaatgcaatatcAACATCGTCATTAGGCACCCAAGCGAATGGCGTCACAGTGCTTGAAACGTTCTCGGCATCGTCAGGAATAACGTCAGCATTGGAGAATGCGCTGACCATTGGCTATCCGGATCCGGACATGTTAGCAGATGTCTTGGGCACCATACAGACCGCCTCACTTAAAACCAAACAAACTAGCAGCAATACTAACATCTATACCAACAACAGTAAACGAAGTAGCTACATCAATGGTAGCAGCAGGAGAAACAGCAGCACTTCAACAACAATTCTGAACAACACCCTAGCAACAACGAGCTCTGGAGTTCATCTGGCCGGTCCAAATAAAATAACGATAACGCGACGAAGTGCCAGCAATAAGATCAGCGTGCAAACTGTAAGCGCTTCCACAAATACAACCATTAGCAGCATTGGCGGCAGTAAGACCAACTACATAAAGAATTGCCTGAtacggagcagcagctgcagcaacacgGCCACCAATGTCACGACGCTGGCGCAGATtatgagcaacagcagcaccagcagcgcaGCCAGTTTACTCAGTCAgcacaataataatagcaactgtagcaacagcagcaattttAGCAACGCCTCATCCGTGGGCAGCAGCATTAgcattggcagcagcagcagcagcagcaacagcagcagcaacgacagcaacagcagcagtggtCACAGTTTAAGCTTCAAGAGCAACGGTCGAAATGTTCCTGGTATTGTAACTGCAGCAGCATCCACGAACACCACAGCCACCGGCATTGGCATTATCACCGTCGATAACGCACCCAGAAAGAGCCGACCCAAACTATCCTCGCCGACTCGTCACGGACCCCAGCAGTGTCAGATTTGTAGCAAGATCTTTGGAAATGCTTCGGCACTGGCCAAGCACAAACTGACGCACAGCGACGAGCGGAAATATATTTGTGCGCTCTGCTCGAAGGCATTCAAGCGGCAAGATCACTTAAACGGACACATGATGACGCATCGCAACAAGAAGCCTTACGAGTGTAAGGCAGATGGCTGCGGCAAATCATATTGCGATGCGCGTTCTCTCCGCCGTCATTCAGAGAATCACCATGGAGGCGTGGCAACGCTCAATAACAACTCACTCTCGCCCACAGCTAGCTCAAACTGCGGCAgcggaagcagcagcagcagcagcagtagtgtGGGTGTGGCCACCAGCTCTCTAAGTCTTTCACCGGCTACAGCTAGTGGGGACGCCAGCTCGCCAGATGGGGCCACTTGCATTCGTACCTACATTTCCACAGGCAGCTCTGTGGTGGATGCTGCCACTGGCATTGCGCTGTCCGATGAACAGATCAAGGCTATGAATTTGCCCATTAAATCGGGAGTCACATTACTGTCGCCCACCACTTCGACATCCTCAATAGCATCGTCGACAACATCCTCATCATGCTCAACATCTGGCGGTAGCTGCAGCTCCGTTCTGACTAGTTCGCCCACAATTACGCTTAGTGATGGCGCAACCTTAGAGGGCGATGGATTAACGCGCGAGCAACTCGATCTCATAAGCAAGATCATGCAACAGACGAAGCAAACCAGTGCCCAGGTGACGGTCTCTTCGCCCAACAGCGTCAGCTCCTATAAGATCAATACAGAGACAGCACCAGTCTCGGCACGTCCACGCACGTGGAACATGCAATTGCTCAATAATGCGCAAAATGTCACCGTAACCGTGGAGGATGGTACCGATATGGTTGCGTCCGCTTCAAGTTCACCCGACGAGGTCAAGGACGATGAATTGAACCAGCAGCTAGTGGCCGCTATTAATCCCCACCTGCTCAATATTGTTAAGATCGACAAGCCAGTTGAGTGCAATCTATGTCACCGCAAGTTCAAAAATATACCCGCTCTTAATGGGCACATGCGTCTGCATGGCGGTTACTTCAAAAAGGATCCGGAAACCAAGCGCAGCGAGAAAAAGGACTCCAACGGACCGCCATTGCAGACTGCGAGCATAGGTGTGCGTGCCCTTATCGAGGAGAAGATCATTAGTAAGCGCAAGGACATCAATAAGGGCGCCTTTGTTGTGCCTGCTCCACCCAGCAGCACCGCAAGCAACGGAGGTGTTGGTGGctgtagcaacaacagcaacagccttCGCCGCTCCTTAAGCGACTTAGAGAGCTTCTTAAATCCGAAGAGTAACACGAGCAGCCTGAGCCAGGCACTAGCCACCAGCACCAGTACTACTACAGCGGTGCTGCCAGCGGCTACCACTATCAAGAGCACCTCTGGGCTAAGTATACAGCAGATTGGACTGCCGCAAAGTATTGAGATCTTCAGCGGAGGTCACAGACATCCCAAAACCCTTAATTTGGGCAGTGGTGCCAATACCATTACCATTACCACCAACAACGTGCCAACGACAACTACCATGAGCGCACTGACGGCTCTTAAGGGCGGCGGTAGCATCAGTGGTGTCACTAGCAACGCGGACTCCAAGGACTCGACGTTAATTGAGTTACTTAAGCGTGGAACGCGCATTGCCGTGGCCTCTAAGAAAACACAGCTACAGGCACAAAACAGTACAAATCTGATCTTAAGCAATGTTGGCGGCTCAGAGCTCACAACCATTAGCAGCAGTGTCCAGACTGGTCGGCAGATTATTACCAACAACAATCGCACCGTCATCATACCTTCTGATGTGCACGTGGTGTCCACCAAGAGCAAGTTAATTTCTAGCAACGCTCTCACAACCAACGACAGCAATACAACTTGTTCTGCAAGCAGTATATCATTGCCAGACGGGACTCCCCTCTCCCTTACCATTACGCCCAGCCAGGAGAGTGTGGGTGTCGGTGAAGCAAACGGCATAGCTGGTGGTGGAGGTGTTTACACTGTAACTTACACTAGCGATGCGGATGCATCCGATCTCTTCGACGACGCTGAGGTGTACAATGTGTCGGACACGGAAATGCTACTGCAAACGGTGGATACTATGGAACTGCTCAACGATGACGAGGATGAAGTGCACAAAAGCGAACATTCCGAGGACTTTTCGCTGCTCAGTGAGGCCAGCGATAATGTTCAAACACGGCTGGTCAAGCTGGAGCCCGATCCTGTACACAGCAGCACAGCCAGCAACCTTAATAAAACAACGCCGTTACCCACCTTTCAGCAATTTCATTCCAAGGAGATTATCATGCAGAACAGTTCTCAAATCCAGGCCATCGCCAACATGCGTGGAAGCAACACCCTAGGCTTGCTTTCGTCACCGTTGCATTCGCCACTAGCCTACCCGACGCCACCCTCTAGCCACGAGAATGTGGCTCAATCCTCACCCTTTGTAGAGGATGCTGCGGCTCAGTTTGTGGATGCCAGTCACACGTTCTTTAGCGATAAAACAGACTTTTCACAAGTCTATTTTAAAACAGACGAGAGCGATTCCATGCAGCAGCTCAGTGATAATGACAATGAGAAAATACTTAAACTAAAGTCGGTGCTGGAAGAAAGCAGCTTCGATCCATCCATTAAGGTGGAAGATCTCTTGAACAGCACCGAGGACGATGCCGAATGCGACCTGCGGGAGTTTGCCGAGACGAATCTCTCATTTCTCGATGAGGATCAGGAGTTCCTAAATGATTCACGAAATGCTACCTCGCCTCTGTCTGAGTCCTTCTTCACCAGTGGCATTGGATCTGCAGAAGATGTTAAGCAGGTGCTACGTGAGGTGCTGCCCGATGAAAATATGCAACTGCAGCTAACTAGCGAGCAGCAGGGCGAGAACATCATTGACCTTTACTATTTACCGGGGCTGGGCCTGCAATCCCAAATGATGCCAAACTCTGATGATCCGCTTTTGTCCTCCTCACCAAGAGAATTCGGACAGCAGCGACAGGTTGTCCAAACGACAACGTCCACGCCATCGACCACACAACCTGTCGAGCAGTTGCAGTCTACCACCGTACTGTACGATCAAcatcaactgcaacagcaactgcaactgcagccccagcaggaacagcaagagcaacaccaggagcaacatcagcagcaacagcatcagcaacagcagcagcaacagcagcagcaacagcaacaagaacagcaatcccagcaacagcaagagcaaatgcaattgccgCAGCAGTCTGCAATTCAATCtgaacaaccacaacaggaacaacagaCAGACTTTATGCTCACCAACTTTACTCCCGTGTCCTGTCAAACACAGTACCTAGATACCAATCAGCAGTCGATGATGCTGCAGCCACTGAATAGTTTGCTGCAGCCAATACTttatggcagcaacagcacctcCAACGATAAACAAGCATTTACCTCGATGCTTAACTCGAATGCCGGTCAGACAACTGAACTGGATGCGAGCCTGCTCTTTGCCTGCGGCGACAGTATCAAAAATAACTGCAGCAAACCTATGCTTGCTGCATTACCTGCAGCAGTAGCTACACCAGTAGTCACTCCAACACCAAGCGTTTCCAATCTACAGCCGCTGTCCAACCAAACTAATTCCATATTAAAGCGTCGCCTGCGTTCAAATGGAGCACAGGATGTGCACAAGTTCTCGAAATTCCAAACACTTTCACCGCATCGCTCAAAGCTACGCAAGCCTTCGCGCACCCACTACACACCCGCGCCAATTCTTAATCCAGATCGCAAGGGCACAGGACTCTATTGCAATGTGCGTAAGCAGCTCGGCCAAGGAATGTTTGACGTCTTTGACGATGACTTTGGCGATCCTGTGGGCTTGGTTGATTTCTGCGATGAGTCCAAGGTGAATCTAGGTTCCACTTATCAAGCGCAGATCCCAGCCTGTAAATCGCCCGAAGAATCCACCAAGGAAACAATGAGTGCAGACCTACTTTGGGATCCAAGCGTACAGATAGACGAGAAGATACTAATGCGTTATATAGATCTCAGCAAATCCTCGGCCGTACCCATGGGTAGCCATTCCGAAGAGGTAGCCCTTCAAACGCTGCTTGAGGCCAAAGGCAACTCAGCGGCGGCGGTGCTCACCCTGTTGCAAACGCAGTCCAGCGCGTTTCAAATGAAATGGACTGCCTATGAGCTAGAGCAGTTTCTACGTGGCCTGGAGAAGCACGGGAaggattttggaaaaattgcCAGCGAGTTACTTACGAAGACCTCGGGCGAATGCGTtcaaatgtattatttttggaaaaaacTATGTGTGGACTACAAGGTCTCTCACTTAAAGATGGAGCCAGTTCCTGCGAGCACTCCAACGGTGGAACAGAAGCCCTACGTCTGCGAGATTGCCGACTGCTCGGCGAGCTTCACCTCGAAAGCAGCTCTGCATGGTCATGTTCGCATACACGCTTATGGCAGAAATGCCAGCAACagtaatagcaacaacaacaacaacaacaaccagcatGCCACGGCAGTTagtgccaacaacaaccatacttgcaacaatagcagcaacaacaatagcaacaacgcATGCGCATCCCAGACTAGTAGCCATACCAATCAATGCaacagtgcaacaacaacaatcataaCGCACGCCAATGGCAATAACTCCACCctcaacaacaatattatcagcaacaacattgcaCCAGGCTCTTCCATAAATACTGCTCtgttatcagcagcagcagcagcaggagcaggaacaGCAGGAACGACATCGACAGCATCAaaagacagcagcaacagcaacaattccaATACAGCCAAGGAGAGTGAATTTCCCTGCAAGGTGTGCGGCAAAGTCTTCAATAAGGTCAAAAGCCGCAGTGCCCATATGAAAACGCATCGAGTACAAGAAGCTGAACAATCATCAAATTCCAAACAGCAATCTAACAATGGAACTCTGTCTGCAGTAACAGTGGCAgtagcagcatcagcagtaCCATCGGCTCCCTCTGCAGTAACAGTTCTGGCCACCGCATCTTCTTAG
Protein Sequence: MAAINTVPKSIHLPLTNLSAPRVLMCSASVGSEGSVTLQLRDANALEAADSTTTATTATATTIATNAISTSSLGTQANGVTVLETFSASSGITSALENALTIGYPDPDMLADVLGTIQTASLKTKQTSSNTNIYTNNSKRSSYINGSSRRNSSTSTTILNNTLATTSSGVHLAGPNKITITRRSASNKISVQTVSASTNTTISSIGGSKTNYIKNCLIRSSSCSNTATNVTTLAQIMSNSSTSSAASLLSQHNNNSNCSNSSNFSNASSVGSSISIGSSSSSSNSSSNDSNSSSGHSLSFKSNGRNVPGIVTAAASTNTTATGIGIITVDNAPRKSRPKLSSPTRHGPQQCQICSKIFGNASALAKHKLTHSDERKYICALCSKAFKRQDHLNGHMMTHRNKKPYECKADGCGKSYCDARSLRRHSENHHGGVATLNNNSLSPTASSNCGSGSSSSSSSSVGVATSSLSLSPATASGDASSPDGATCIRTYISTGSSVVDAATGIALSDEQIKAMNLPIKSGVTLLSPTTSTSSIASSTTSSSCSTSGGSCSSVLTSSPTITLSDGATLEGDGLTREQLDLISKIMQQTKQTSAQVTVSSPNSVSSYKINTETAPVSARPRTWNMQLLNNAQNVTVTVEDGTDMVASASSSPDEVKDDELNQQLVAAINPHLLNIVKIDKPVECNLCHRKFKNIPALNGHMRLHGGYFKKDPETKRSEKKDSNGPPLQTASIGVRALIEEKIISKRKDINKGAFVVPAPPSSTASNGGVGGCSNNSNSLRRSLSDLESFLNPKSNTSSLSQALATSTSTTTAVLPAATTIKSTSGLSIQQIGLPQSIEIFSGGHRHPKTLNLGSGANTITITTNNVPTTTTMSALTALKGGGSISGVTSNADSKDSTLIELLKRGTRIAVASKKTQLQAQNSTNLILSNVGGSELTTISSSVQTGRQIITNNNRTVIIPSDVHVVSTKSKLISSNALTTNDSNTTCSASSISLPDGTPLSLTITPSQESVGVGEANGIAGGGGVYTVTYTSDADASDLFDDAEVYNVSDTEMLLQTVDTMELLNDDEDEVHKSEHSEDFSLLSEASDNVQTRLVKLEPDPVHSSTASNLNKTTPLPTFQQFHSKEIIMQNSSQIQAIANMRGSNTLGLLSSPLHSPLAYPTPPSSHENVAQSSPFVEDAAAQFVDASHTFFSDKTDFSQVYFKTDESDSMQQLSDNDNEKILKLKSVLEESSFDPSIKVEDLLNSTEDDAECDLREFAETNLSFLDEDQEFLNDSRNATSPLSESFFTSGIGSAEDVKQVLREVLPDENMQLQLTSEQQGENIIDLYYLPGLGLQSQMMPNSDDPLLSSSPREFGQQRQVVQTTTSTPSTTQPVEQLQSTTVLYDQHQLQQQLQLQPQQEQQEQHQEQHQQQQHQQQQQQQQQQQQQEQQSQQQQEQMQLPQQSAIQSEQPQQEQQTDFMLTNFTPVSCQTQYLDTNQQSMMLQPLNSLLQPILYGSNSTSNDKQAFTSMLNSNAGQTTELDASLLFACGDSIKNNCSKPMLAALPAAVATPVVTPTPSVSNLQPLSNQTNSILKRRLRSNGAQDVHKFSKFQTLSPHRSKLRKPSRTHYTPAPILNPDRKGTGLYCNVRKQLGQGMFDVFDDDFGDPVGLVDFCDESKVNLGSTYQAQIPACKSPEESTKETMSADLLWDPSVQIDEKILMRYIDLSKSSAVPMGSHSEEVALQTLLEAKGNSAAAVLTLLQTQSSAFQMKWTAYELEQFLRGLEKHGKDFGKIASELLTKTSGECVQMYYFWKKLCVDYKVSHLKMEPVPASTPTVEQKPYVCEIADCSASFTSKAALHGHVRIHAYGRNASNSNSNNNNNNNQHATAVSANNNHTCNNSSNNNSNNACASQTSSHTNQCNSATTTIITHANGNNSTLNNNIISNNIAPGSSINTALLSAAAAAGAGTAGTTSTASKDSSNSNNSNTAKESEFPCKVCGKVFNKVKSRSAHMKTHRVQEAEQSSNSKQQSNNGTLSAVTVAVAASAVPSAPSAVTVLATASS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00531181;
90% Identity: iTF_00491009;
80% Identity: iTF_00616838;