Basic Information

Insect: Drosophila kuntzei
Gene Symbol: PZF1
Assembly: GCA_035042165.1
Location: JAWNLU010001808.1:1556194-1558674[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.068 5.1 7.9 0.2 3 23 297 318 296 318 0.91

2 10 8.6e-05 0.0064 17.0 0.3 6 23 327 344 327 344 0.99

3 10 9.5e-06 0.0007 20.1 0.3 1 23 350 373 350 373 0.98

4 10 0.00016 0.012 16.2 1.3 1 23 385 407 385 407 0.98

5 10 9e-05 0.0066 17.0 3.0 1 23 414 437 414 437 0.96

6 10 1.3e-05 0.00099 19.6 1.8 1 23 443 465 443 465 0.96

7 10 0.1 7.7 7.4 0.5 2 23 474 495 473 495 0.96

8 10 0.00029 0.022 15.4 1.9 3 23 502 523 500 523 0.92

9 10 2e-07 1.5e-05 25.3 0.7 2 23 530 551 529 551 0.97

10 10 0.0002 0.015 15.9 4.4 1 23 557 580 557 580 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.068	5.1	7.9	0.2	3	23	297	318	296	318	0.91
2	10	8.6e-05	0.0064	17.0	0.3	6	23	327	344	327	344	0.99
3	10	9.5e-06	0.0007	20.1	0.3	1	23	350	373	350	373	0.98
4	10	0.00016	0.012	16.2	1.3	1	23	385	407	385	407	0.98
5	10	9e-05	0.0066	17.0	3.0	1	23	414	437	414	437	0.96
6	10	1.3e-05	0.00099	19.6	1.8	1	23	443	465	443	465	0.96
7	10	0.1	7.7	7.4	0.5	2	23	474	495	473	495	0.96
8	10	0.00029	0.022	15.4	1.9	3	23	502	523	500	523	0.92
9	10	2e-07	1.5e-05	25.3	0.7	2	23	530	551	529	551	0.97
10	10	0.0002	0.015	15.9	4.4	1	23	557	580	557	580	0.96

Sequence Information

Coding Sequence: ATGATCTGTCGATTgtgtttaaaaaacataaactcAAACAATGCCGTCTTTCTGTTTGAAACGGACGACACACTAGCCGAATCCTCGCTGCTCAAAATGATAGCAAAGTTCCTGCAACTCGAAATAATGCCGGATGATAACATCTCGACAAACATTTGCCACGAGTGCTGTGAACATTTGGAGGATTTCAACAACTTCTGGCAGCTGGTGGAACAAAAACAAGGCACTCTCAAAAAGGAATTCCTCAACGTGGACGTCGATTGTGTGGCCCTGAAATGGACAGGGGGCATCGATGTGGATGTGAGCATCGACGAGCTGCCGCTTGTGGCCGATGAGATGGACGAGAAGCCACTGGATATACATAATCTCAGCCTGCTTGGCAGTGTACTCGATGTTAATGTGGACAGTGTCGAGGTGCCGCATTCAAAGCAATCGCATCACAAGGAATTGATGCCACTGAACGCAGCTGAAGATGATTGTGATGCGGATGAGAAGCCGCTCATCCATGACGGCAGTGACCACAGTGCGAGAAACTTTccctcctcctccgcctccgcttcctccgatgatgatgatgatgATGAAGTGCCTCTGGTGAAGCTGCAGCACAAATTGAAACCGAAGCGAAAAGTACGCGCCACACGTCGCAAGCAACGGACATTAACACTGGCCCAGGAGCTGGATCAGTTGCTGGAAGAGAGCAACGTTGATACCAGCAGCAAAGTGCGACGCAAGAAAAtgacaaatacaaatgtaaattcaaatatgCCAACGGATACACAAAAGGATGAACTGGAGGCGGCAATGGAACGGCGTCCCAAGGGCTGTTCCCGTGCCCAGCTATCGAAGCGCTATGAGGAGGCCATTGCCAGTTACATGAGCGCCGACTGTGATCTGTGCGATTTCAGTGCCAAGTACCTGTCCCAACTGAAAGTCCACTTCCTCGAGGTGCATCAACAGGACGCGTATCTCAAGTGTTGCAACAAAGTCTTCAATCGACCCTCCAAGCTAATGGATCACATTCGCAAGCACATCAATCCCAAGCTCTTTACGTGCTCCATCTGCAACAAATCGTTGAACTCGCAGGATTATCTGGCCACGCACATAGAAACGGTGCACAATAAGGTTGCCAAGATTGGCAAGGTGTTGAATTATCCGTGCTCCAAGTGCGAGCGAACTTTCAGCAGCGAGCGTCGTCTGTCCAATCATGTGATGAAACATGATACGGATCAATTGGAGCACAGTTGTCAGATTTGTGAAAAgagCTTTGCCAATGTGCATCGACTGAGACGGCACATTCAATCCATACACGAGGATCTGCATCCACATGTCTGCGATATTTGTGGCAAGAAGTTCAAATTTAAGCCCTCATTTGAGCGTCATCTGCTGGAGCATCAAGGTGTCGTATCACCTGCCATGGAGTGTCCCGTCTGCGGTGTATGGCTGAAGAATGAGCACAGTCTGCGATTGCATCGCTTCACACACGATAGCACCAATACCATCTGTCCGCATTGCTCCAAGACGTGCAGTTCCCGCACTGCGTTGCGTGCCCACGTTGAATACGCCCACAAATTGACGACAAGTCTGCAGTGCACGTATTGTGAGAAGAGCTTCAAGCAGCAGCGTAATCTGGAGGAGCACATGGCCATACACACGGGATTGCAGCTATACAATTGCCCGCATTGTCCCAAGGAATGCCGTTCCCGTTCCAACATGTATGTGCACATCAAGCAACGACATGCGGATGAATGGCTCAAGGCTAAAATGGCCCGATCCCATAATCCACAATTCAAGCCACATGCCTAg
Protein Sequence: MICRLCLKNINSNNAVFLFETDDTLAESSLLKMIAKFLQLEIMPDDNISTNICHECCEHLEDFNNFWQLVEQKQGTLKKEFLNVDVDCVALKWTGGIDVDVSIDELPLVADEMDEKPLDIHNLSLLGSVLDVNVDSVEVPHSKQSHHKELMPLNAAEDDCDADEKPLIHDGSDHSARNFPSSSASASSDDDDDDEVPLVKLQHKLKPKRKVRATRRKQRTLTLAQELDQLLEESNVDTSSKVRRKKMTNTNVNSNMPTDTQKDELEAAMERRPKGCSRAQLSKRYEEAIASYMSADCDLCDFSAKYLSQLKVHFLEVHQQDAYLKCCNKVFNRPSKLMDHIRKHINPKLFTCSICNKSLNSQDYLATHIETVHNKVAKIGKVLNYPCSKCERTFSSERRLSNHVMKHDTDQLEHSCQICEKSFANVHRLRRHIQSIHEDLHPHVCDICGKKFKFKPSFERHLLEHQGVVSPAMECPVCGVWLKNEHSLRLHRFTHDSTNTICPHCSKTCSSRTALRAHVEYAHKLTTSLQCTYCEKSFKQQRNLEEHMAIHTGLQLYNCPHCPKECRSRSNMYVHIKQRHADEWLKAKMARSHNPQFKPHA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00601987;
90% Identity: iTF_00519339; iTF_00586123; iTF_00583857; iTF_00558077; iTF_00608600; iTF_00523123; iTF_00507046; iTF_00575767; iTF_00534006; iTF_00585378; iTF_00601987;
80% Identity: -