Basic Information

Insect: Drosophila putrida
Gene Symbol: PZF1_1
Assembly: GCA_037043535.1
Location: JBAMBI010000732.1:776498-778565[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.064 4.4 8.0 0.2 3 23 274 295 273 295 0.91

2 10 8e-05 0.0055 17.1 0.3 6 23 304 321 304 321 0.99

3 10 8.8e-06 0.00061 20.1 0.3 1 23 327 350 327 350 0.98

4 10 1.8e-05 0.0012 19.2 0.7 1 23 362 384 362 384 0.98

5 10 0.00021 0.015 15.8 3.3 1 23 391 414 391 414 0.96

6 10 1.2e-05 0.00085 19.7 1.8 1 23 420 442 420 442 0.96

7 10 0.096 6.6 7.4 0.5 2 23 451 472 450 472 0.96

8 10 0.00012 0.0081 16.6 2.8 2 23 478 500 477 500 0.95

9 10 1.9e-07 1.3e-05 25.4 0.7 2 23 507 528 506 528 0.97

10 10 0.00019 0.013 16.0 4.4 1 23 534 557 534 557 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.064	4.4	8.0	0.2	3	23	274	295	273	295	0.91
2	10	8e-05	0.0055	17.1	0.3	6	23	304	321	304	321	0.99
3	10	8.8e-06	0.00061	20.1	0.3	1	23	327	350	327	350	0.98
4	10	1.8e-05	0.0012	19.2	0.7	1	23	362	384	362	384	0.98
5	10	0.00021	0.015	15.8	3.3	1	23	391	414	391	414	0.96
6	10	1.2e-05	0.00085	19.7	1.8	1	23	420	442	420	442	0.96
7	10	0.096	6.6	7.4	0.5	2	23	451	472	450	472	0.96
8	10	0.00012	0.0081	16.6	2.8	2	23	478	500	477	500	0.95
9	10	1.9e-07	1.3e-05	25.4	0.7	2	23	507	528	506	528	0.97
10	10	0.00019	0.013	16.0	4.4	1	23	534	557	534	557	0.96

Sequence Information

Coding Sequence: ATGATCTGTCGCTTGtCCGAATCATCGTTGCTCAAAATGATAGCCAAGTTCCTGCAACTGGAAATAATGCCAGATGACAACATTTCGACAAATATTTGCCACGACTGCTGTGAACATTTGGAGgatttcaacaatttctggCAGCTGGtggaacaaaaacaaagcacactCAAAAAGGAATTCCTCAACGTGGATGTGGATTGTGTTGCCCTTAAATGGACTGGAGGCATTGATGTGGATGTCAACATTGATGAGCTCCCTCTGGTCGCAGATGAGATGGACGAGAAGCCCTTGGATATACATAATCTAAGTCTGCTTGGCAGTGTGCTGGATGTCAATGTGGACAGTGTGGACGTGACCCATCCAAGGCAATCCCAGCGTAAAGAACTCATGCAGTTGgatttaaatgttgattatGATGCagatgcggatgcggatgaGAAGCCGATAATTAATGATAACAGCGACAACAGTGCGAGAAACTTCtcttcctcctcatcctcctcctccacagATGATGAAGATGACGAAGTGCCTCTGGTGAAGCTGCAGCACAAGCTGAAGCCCAAGCAAAAAGTTCGTGCCCCGCGTCGCAAACAACGAACCTTGACTCTGGCTCAGGAGCTAGATCAGTTGCTCGAGGGGAGCTCGAGGGGCAATAGCAAAGGTCGACGTAAGAGgttaacaaatacaaatacgccAACGGATTCACAAAAGGATGAACTGGAGGCAGCAATGGAGCGACGTCCCAAAGGCTGTTCCCGTGCCCAGTTATCGAAACGCTACGAGGAGGCAATTGCCAGCTATATGAGCGCTGACTGTGACCTGTGTGATTTCAGTGCCAAGTACCTGTCCCAGTTAAAAGTCCATTTCCTTGAGGTGCATCAACAGGATGCGTATCTCAAGTGCTGCAACAAGGTGTTCAATCGACCCTCCAAGCTAATGGATCACATTCGCAAGCACATCAATCCCAAGCTCTTCACGTGTTCCATATGCAACAAATCGTTAAACTCACAGGATTATCTGGCAACGCATATAGAAACTGTGCACAATAAGGTTGCCCAGATTGGCAAGGTGTTGAAGTATCCATGTCCCAAGTGCGATAGAACCTTTAGCAGCGAACGTCGATTGTCAAATCATGTGCTGAAACATGATACGGATCAATTGGAGCATAGTTGTCAGATCTGTGAAAAGAGATTTGCCAATGTACATCGATTGAGACGACATATTCAGTCCATCCACGAGGATTTGCATCCACATGTCTGCGATATTTGTggtaaaaagtttaaatttaagccCTCCTTTGAACGACATCTTCTGGAACATCAAGGTGTCGTTGCACCTGCCATGGAGTGTCCTGTATGTGGAGTGTGGCTAAAGAATGAGCATAGTCTGCGACTGCATCGCTTTACACACGATAGCACCGATACCGTCTGTCCACATTGCTCCAAAACGTGCAGTTCCCGAACAGCGTTACGTGCCCATGTCAAATATGCCCATAAATTGACCACAAATCTGCAGTGTACGTATTGTGAGAAGAGCTTTAAGCAACAGCGCAATCTGGAGGAGCATATGGCCATACACACGGGATTGCAGCTCTACAATTGCCCGCATTGTCCCAAGGAATGTCGTTCACGTTCCAACATGTATGTGCACATCAAACAACGACATGCCGATGAATGGCTCAAGGCGAAAATGGCCCGATCCCATAATCCACAATTTAAGCCACATGCCTAG
Protein Sequence: MICRLSESSLLKMIAKFLQLEIMPDDNISTNICHDCCEHLEDFNNFWQLVEQKQSTLKKEFLNVDVDCVALKWTGGIDVDVNIDELPLVADEMDEKPLDIHNLSLLGSVLDVNVDSVDVTHPRQSQRKELMQLDLNVDYDADADADEKPIINDNSDNSARNFSSSSSSSSTDDEDDEVPLVKLQHKLKPKQKVRAPRRKQRTLTLAQELDQLLEGSSRGNSKGRRKRLTNTNTPTDSQKDELEAAMERRPKGCSRAQLSKRYEEAIASYMSADCDLCDFSAKYLSQLKVHFLEVHQQDAYLKCCNKVFNRPSKLMDHIRKHINPKLFTCSICNKSLNSQDYLATHIETVHNKVAQIGKVLKYPCPKCDRTFSSERRLSNHVLKHDTDQLEHSCQICEKRFANVHRLRRHIQSIHEDLHPHVCDICGKKFKFKPSFERHLLEHQGVVAPAMECPVCGVWLKNEHSLRLHRFTHDSTDTVCPHCSKTCSSRTALRAHVKYAHKLTTNLQCTYCEKSFKQQRNLEEHMAIHTGLQLYNCPHCPKECRSRSNMYVHIKQRHADEWLKAKMARSHNPQFKPHA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00601987;
90% Identity: iTF_00528989;
80% Identity: -