Basic Information

Gene Symbol
hang
Assembly
GCA_018903935.1
Location
JAEIFP010002303.1:12746978-12754583[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 0.2 15 6.3 1.0 3 23 312 333 311 333 0.93
2 16 0.14 11 6.7 3.5 3 22 437 456 435 456 0.89
3 16 0.00042 0.033 14.7 3.3 1 22 561 582 561 584 0.90
4 16 0.049 3.8 8.2 0.1 2 21 596 615 595 616 0.93
5 16 0.00049 0.039 14.5 0.2 2 23 750 772 749 772 0.95
6 16 0.0014 0.11 13.0 0.1 1 23 780 803 780 803 0.96
7 16 1.1e-05 0.0009 19.6 0.1 2 23 891 912 890 912 0.97
8 16 0.0002 0.016 15.7 2.9 2 23 1012 1034 1011 1034 0.97
9 16 0.016 1.2 9.7 0.2 2 23 1043 1065 1042 1065 0.95
10 16 0.0024 0.19 12.3 0.3 1 22 1078 1099 1078 1107 0.95
11 16 0.0014 0.11 13.1 0.9 1 23 1115 1138 1115 1138 0.96
12 16 0.3 24 5.7 1.5 2 20 1146 1164 1146 1164 0.96
13 16 0.00035 0.028 14.9 0.2 3 23 1261 1281 1260 1281 0.98
14 16 0.0036 0.28 11.8 0.1 1 23 1316 1338 1316 1338 0.97
15 16 0.00043 0.034 14.7 0.7 2 23 1419 1441 1418 1441 0.93
16 16 1.4 1.1e+02 3.6 0.1 2 20 1461 1479 1460 1481 0.91

Sequence Information

Coding Sequence
ATGCTTGTATTAGCTATCTTAATTCATGGCAAAGTTTTAAAAATCGCTGCCTTAGCTCGCAAACCAAACAGCGGCAATGGCTGGAGACATCAACAGCATCGACGACGACGACGTCGACAACATCAACGACATCATTCCCATTCTCATTCTCATCCTCATCATCATTATCAGCAACAGCAGCAACCATTTCGTAAATACCAACAGCAAAGAAGTAGACAACAGCAGACACAATCATATCAATATACACCAAGACGTTCGCGTCAGCATCAAGGAAGACGTGGTCCTGGTCATGTAGTCGCTGCATCTACACCTACACCTAATCCCACTGGTCATGCCACTTCCATGCGCAAATTGAAAACAAAAATGTATTTACCCTTAGATATAACCGTTCCAACATCGCCAATACATCTTACCGGTGGTGTTCCTCCTCCACCTCCACCGTCTCCTCCTCCACCTCCTCCACCACCTCCTCCACCTTCTTTATCTTTGTCAACTGCTGTCTTACCGCTACCACCGCCAAAGCCACTGTTAATGCCAATGGCTGCTGCCCCATCAACATATTCAACGACAACGACTGCCACTGCGACTGCGGCACCGCTGCTAATGCCAGTGACGTTGCAAAGCGCCACACAGCAATTGCGATTTTTCAGACGCTATTCCTATAATCCTCTGCCTGCTGTACCCATCAAAGATGAGCCTATAGACGATACCGATGATGACTATCAAATGAAGTCCATAGATGAATCCATAGATGATATGGTTGATCCCACAATGTTCCTAGAGCGTTCTGAGCATGAAGGCGATGTCCCATTGATGACATCGGATTATGATTATACGGCTCAGCATGGTGTTACAGCAGCTGCTGCGGCTGCTGCTCTACCAGCTAGCGCTGTGGCCAGTGTCGCCGCTGCTGGTGACTCAAAAGTGGCCAGCTGCCGGGCATGTAGCCTACAGTTCTCCACACGAGCCAATGCCCGACGACATGAGCGTAATCTGCATCCGAATCTCTTTCAATTGTCCACCGATTCGCCCAACAATACCCCAGTTACAAAGCCAACGCCGGCTCTGGCTGCCGCATTGGAAATCCAACGGGCCGCCGCTGCGGCAGCCTCAGCCGAGGCAAGTCGTTCCGGCGGCAATATGTCTACGCAAAAGTATCGTCAGGTGGTAATGAATGCCTTTATCAAATGTGAAGCCGGCGGCTATGACTATGATAATCCCGAGCAATATCAATCCTTGCTGAGTCGCGACAAAGTTGAATTTATCGAGCAGAATGCCGAATTCCTTGAGCAATATCAGACGATGACTTGTCGTTGTTGCAATAAATTCTTTAGCACCTATAAAAATTTTATGGCCCATGTGCGCAAGAAGTATCCATTATTGCCGCGTAATCTCTGTTTCAATTGCCTCAAGATGAATGATTCGAAGGCTTTGTTTATATCACATCTGAAGAAGCGCAACTGCATCAATCTGTACAGAGTTATGAATGCCATCAACAACAAGCAGCAGCAACAGCAGAACGATGGAGCTTCAGTTGCTCCATCGCCTGCTGCTGTACCAGTTGTTGTCCCAGCGGCGGTGACAATTGTGTCTGGTTCCAGCGGAACAAGTGGCACAACAACAACAACATCCGATCGGCCAGAAAAGCTGCGAGCCAAAGAGCTTCTTGTCAATAAACTATACGAATGCAAACTGTGTCCAAAAGGTTTTCGCACCAAACATGAATTCCGTACCCATGTCTATGATAAGCATGCGGATGTTCAGCGCAAAGATAACAATTCCATTCAGTGTAGTTTCTGTGGCTTGGACTTTGCCGATCCTGTGGACAGGCGGCGTCACTACAACAACATGGACTGTATTGTTCGCTTGCGTTGCATGACCTGTGATGCCAAATTGGAGACGCATCAGCGATTCCTCGATCATGTCTATCAGGATCATTTGGGCGGCTTGAGCAGTGATAATGTCTCATCGACGACTGTGATTGGTACAACTAATGTGGATAATTCCCATTCGCCGGGCAAGAAGAATGCGTTGGGTGCATTGGGCATGGGATCGGCAGATGAATCTCGTAGTGCGGCCACCCCATCGCTAATAACTTCCACACCAAAGCCAGCTGGTGGAGCAGCTGCTGCAGTGACAGCTAGTGGTGGTTTATTAGGTGGTGGTGCCGTGGCATCGGCAGCAGCGGCGGCCAATCGTGATCGTGATGGAGCTCCAAAATCTCAATATTTCTCCCGCATGCCCCAGGTCTGTCCCATTTGCGGGCAGCAGTATAACAACTACAACAATGTTCTCCGTCACATGGAATCCAAGCATCCCAATAAACTGCCCGAAACATATAAATGTGTACGTTGCGGTTTGGGCTATCCACGAATCTCTTATCTGCGTGAGCATATGATCAATGTCCATGGTGTTGATAAAAATCGCCATTCTGGCGGATTTGAGTATATTGTTAATGCGGATGCCGTTAAATTAGCCGATGGCAGTACACCCAATGTCTATACGGGCCGTTATGATTATGTGATGAAGGATCTGATGTCGATAACAAATGGTGGGACCCTCGATGATGACGACGACGAGGGAACAACTGGCAGTGTGGCCAAAAAGATACGATTGGATGACAGCAGTAATAATAGCAGTCTAATGGGCATGGCCGCCACACAGCAAAAGGAATGTCCCATTTGCAATGCAGTATTTAGTAACAATATTGGTCTATCCAATCACATGCGTTCACATTACACAGCCTCAGCGAATGCCTCGGCATCGGCGAATGCTTCTGCCTCGACGTCTGCCTCATCTAGCACAAATGCCGCCTTGGCTGCTGCCAATCGTATGACACCCAAATCATTGACCATAACAGCTGCTCCCCCAATTACAGCGGATAATGCAGCAACACCATCAAATAAAACCAAAACAGCCTCGGCGGAGACAAACTCTCTGGCCTCTTCGTCATCGGCGGCCGCACCTCAAGTACAGGCAATACAATTTCGTCGTAGTTTGGATCAGGCAGCCGATCGTCGTTTCCGGCGTATGCGTTGTCGCATATGCCAGCGACGCTTTAGCTCCAAGAAATCCTATCGTTATCACATGCTTACCGACCATCAAGTGCAGAATGTCCAGTTTATCAAGTGCAAACTTTGTAATGCTGAATTCGCCTACGAAAAGGGATTGAAAGTGCATCTGTTTAAGGTGCACGGCAAGGCCATAAAAGATGAGATGATAATTAAACAATTTGAATGCGAAATTTGTTCCATAGTCTACAGTTCGGAGATGGAATTGCAGCAGCACAAACGAAGCTTGGCCATTCACATCAATTCCCATGATGAATTCGATTCCAATGATTATTCGTGCAAAGACTGCGGCAATGTCTACAGTGGCAGAAAAAGTCTCTGGGTTCATCGCTATAAGAAACATCCCCAAGTGCCTGATCCGGCCGAGTGTTGCCTATGCCGCAAAGTATTTTTCGATCGCCAAATGCTGGACAATCATATGCCCACTTGCAATCGTAAGCCGATAACCTCCACAGGTGCTCATCAACAGCCACAACAACAGCAGCAGCACCACCACCAAAATCAACAAGATCAGCTGAGACGAGGTTTAGTTGTGTTCAAGCACAAAACTGGCGACGACGATGACGATGAGGAAGAGGATGTTGAACAGCAAACACAACTTAATTTGGAAGATGGAACTGATGAGGCTTTGGCGCCCAGCGCTGCAGCGGCTGCTTCCTCATCATCGTCAGCGGCAGCTCATGTCAAGATACGCATACCTGAGGTGGCTTGCACCATTTGTGGAGCACGCTTTATAGAGCAGGAAATGTTTACCAAGCACATACAGAAACATGAACAGGAATTGTATGTAGATAATCCATTGGCGGCTATGTTCGACGATAGTCCAGCTGATCCGGGACAATTCCAAGTGGAGCGCCAGAACGAGAATGGGGAATATGCATGCGATTTGTGTGCCAAGACATTCCCACAAGTGATTGCACTTAAGGTGCATCGCAAATGGCATTTCAGAGGTGATAGCAAGCAGAACCCCATCGACGGCGAAGCGACACAGTTGAACAACAACAACAACAACAATTCGATGTTGCATCTACGCGAACTGCATGCAGTGGGTCTAGTGCCCAATCAACAGCAGCAACAACTGAACTCCAGCCACAATCAGAGCCAGCAGCAGCAGAGCCACAATTCGTCAGCGACTTCCACGACGGGATCAGCAAACAAATCGCTGAAACGGAAACGTGAATTGAAATGTGATTATTGCGCTTCCACCTTCATCAGCAACAACAATCTGCGTCGTCACATGTATGAGCTGCATAAACATGAGGTTAGCCATTTGCCCGAACCACCGGTCATTGTTGTGGATGAGCCGCTCTCATGCCGTCGTTGTGATCTACAATTCGATACAAAAGAATTGTGGATTGAGCATAAATTGGCCGATGCGAAAGTGAAGACCCGTAGCCACATCGACTACGTCATCATCGGAGAGTGA
Protein Sequence
MLVLAILIHGKVLKIAALARKPNSGNGWRHQQHRRRRRRQHQRHHSHSHSHPHHHYQQQQQPFRKYQQQRSRQQQTQSYQYTPRRSRQHQGRRGPGHVVAASTPTPNPTGHATSMRKLKTKMYLPLDITVPTSPIHLTGGVPPPPPPSPPPPPPPPPPPSLSLSTAVLPLPPPKPLLMPMAAAPSTYSTTTTATATAAPLLMPVTLQSATQQLRFFRRYSYNPLPAVPIKDEPIDDTDDDYQMKSIDESIDDMVDPTMFLERSEHEGDVPLMTSDYDYTAQHGVTAAAAAAALPASAVASVAAAGDSKVASCRACSLQFSTRANARRHERNLHPNLFQLSTDSPNNTPVTKPTPALAAALEIQRAAAAAASAEASRSGGNMSTQKYRQVVMNAFIKCEAGGYDYDNPEQYQSLLSRDKVEFIEQNAEFLEQYQTMTCRCCNKFFSTYKNFMAHVRKKYPLLPRNLCFNCLKMNDSKALFISHLKKRNCINLYRVMNAINNKQQQQQNDGASVAPSPAAVPVVVPAAVTIVSGSSGTSGTTTTTSDRPEKLRAKELLVNKLYECKLCPKGFRTKHEFRTHVYDKHADVQRKDNNSIQCSFCGLDFADPVDRRRHYNNMDCIVRLRCMTCDAKLETHQRFLDHVYQDHLGGLSSDNVSSTTVIGTTNVDNSHSPGKKNALGALGMGSADESRSAATPSLITSTPKPAGGAAAAVTASGGLLGGGAVASAAAAANRDRDGAPKSQYFSRMPQVCPICGQQYNNYNNVLRHMESKHPNKLPETYKCVRCGLGYPRISYLREHMINVHGVDKNRHSGGFEYIVNADAVKLADGSTPNVYTGRYDYVMKDLMSITNGGTLDDDDDEGTTGSVAKKIRLDDSSNNSSLMGMAATQQKECPICNAVFSNNIGLSNHMRSHYTASANASASANASASTSASSSTNAALAAANRMTPKSLTITAAPPITADNAATPSNKTKTASAETNSLASSSSAAAPQVQAIQFRRSLDQAADRRFRRMRCRICQRRFSSKKSYRYHMLTDHQVQNVQFIKCKLCNAEFAYEKGLKVHLFKVHGKAIKDEMIIKQFECEICSIVYSSEMELQQHKRSLAIHINSHDEFDSNDYSCKDCGNVYSGRKSLWVHRYKKHPQVPDPAECCLCRKVFFDRQMLDNHMPTCNRKPITSTGAHQQPQQQQQHHHQNQQDQLRRGLVVFKHKTGDDDDDEEEDVEQQTQLNLEDGTDEALAPSAAAAASSSSSAAAHVKIRIPEVACTICGARFIEQEMFTKHIQKHEQELYVDNPLAAMFDDSPADPGQFQVERQNENGEYACDLCAKTFPQVIALKVHRKWHFRGDSKQNPIDGEATQLNNNNNNNSMLHLRELHAVGLVPNQQQQQLNSSHNQSQQQQSHNSSATSTTGSANKSLKRKRELKCDYCASTFISNNNLRRHMYELHKHEVSHLPEPPVIVVDEPLSCRRCDLQFDTKELWIEHKLADAKVKTRSHIDYVIIGE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

90% Identity
-
80% Identity
-