Basic Information

Insect: Drosophila ezoana
Gene Symbol: RREB1
Assembly: GCA_035045725.1
Location: JAWNOU010000058.1:1003335-1009623[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 0.006 0.43 11.3 0.6 1 21 245 265 245 267 0.96

2 13 0.00034 0.024 15.2 0.2 1 23 277 299 277 299 0.98

3 13 8.3e-05 0.0059 17.2 7.3 1 23 305 327 305 327 0.98

4 13 0.79 56 4.6 1.8 2 20 543 561 543 563 0.93

5 13 0.0091 0.64 10.7 0.1 1 23 713 735 713 735 0.97

6 13 1.3e-05 0.0009 19.7 0.7 1 23 745 767 745 767 0.99

7 13 0.00085 0.06 14.0 2.0 1 23 773 796 773 796 0.97

8 13 0.003 0.22 12.2 2.0 1 23 1057 1080 1057 1080 0.95

9 13 8.8e-05 0.0063 17.1 0.3 2 23 1424 1445 1423 1445 0.97

10 13 0.15 11 6.9 6.3 1 23 1451 1474 1451 1474 0.97

11 13 9.6 6.8e+02 1.2 3.4 1 23 1591 1614 1591 1614 0.78

12 13 0.0086 0.61 10.8 0.5 3 23 1677 1697 1675 1697 0.96

13 13 0.0014 0.097 13.3 4.8 1 23 1703 1725 1703 1725 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	0.006	0.43	11.3	0.6	1	21	245	265	245	267	0.96
2	13	0.00034	0.024	15.2	0.2	1	23	277	299	277	299	0.98
3	13	8.3e-05	0.0059	17.2	7.3	1	23	305	327	305	327	0.98
4	13	0.79	56	4.6	1.8	2	20	543	561	543	563	0.93
5	13	0.0091	0.64	10.7	0.1	1	23	713	735	713	735	0.97
6	13	1.3e-05	0.0009	19.7	0.7	1	23	745	767	745	767	0.99
7	13	0.00085	0.06	14.0	2.0	1	23	773	796	773	796	0.97
8	13	0.003	0.22	12.2	2.0	1	23	1057	1080	1057	1080	0.95
9	13	8.8e-05	0.0063	17.1	0.3	2	23	1424	1445	1423	1445	0.97
10	13	0.15	11	6.9	6.3	1	23	1451	1474	1451	1474	0.97
11	13	9.6	6.8e+02	1.2	3.4	1	23	1591	1614	1591	1614	0.78
12	13	0.0086	0.61	10.8	0.5	3	23	1677	1697	1675	1697	0.96
13	13	0.0014	0.097	13.3	4.8	1	23	1703	1725	1703	1725	0.99

Sequence Information

Coding Sequence: atGCTGgccgcacagcagcagcagcagccacaacagcaacacacagcggcaacagcaacgggaGGCAGCACAGTAGGGCTTGCGGATGCGGGCTTGGAGCGGGCGCGTCGCGATTCGAGCACCTCGGAGTCCTCGCTGGAGCATCTGGACTTGAGCCGCACGCCAAAGaagctcagcagcagcagcggcgcgcCGCagccgacgtcgacgccgcACGAGGCGACGTCGCGCAAGCGCAagctgcgccagctgcagcagccgcaacagttGCTCTCCGACGAGGatgaggagcagctgcagcagcagcaacagcagcagcagcaacaactgctggAGCAGTCCGCGCAGCGACTGCGGCACAAGCAGCGACGCAGCGGAAAtgcagccgcagtcgctgctgccgccgctgccagcgCCAGCATCGTGGTCGACTACAGCGCCGGCGGCGATGCTAGTTCGCTGCGCAAAAAGTTTCGCCTGAATCGCAGCAGCGCGAGCAGCATCAATGGCAACAACGGGGAGCTCTCCGAGTCTGGCTTTGTGGATGGCAGCGCGCACAGCGGCTATTTGCTCAGCGCCAGCAGCGCGGCGCAGTCAGCGtcggcagcgcagcagcagcaacagcagcagcagcagttggcctCAAGCAGCAGCTCCGGCGGCAGCTCGCCCCAAGGCCTGTGCCACTCGAGCGCCGAGTCCGGCATCGGTGCCGGCGACGAGCACATGAAATATGTTTGCCCCATCTGCGAGGTCGTCTCGGCCACGCCCCACGAGTTCACCAATCACATACGCTGCCACAACTACGCCAACGGCGACACCGAGAACTTCACCTGCCGCATCTGCTCCAAGGTGCTATCGTCCGCCTCCTCGCTGGACAGGCACGTGCTGGTGCACACGGGCGAGCGTCCATTCAACTGTCGCTATTGCCATTTGACATTCACGACGAACGGCAACATGCACCGGCACATGCGCACCCACAAGCAGCACCAGACGACGCAGCAGCCGACGCAGCAACAGACACCGCAGCAACAGACACCGCAGCAacatgcacagcagcaacatgcacCGCAGCAACATgcacagcatcagcagcagcgacggcagcaacATGCAGGCGCGGCAGCTGGGCGCGCGGAGAGCTACGAGAGCGATGCCAGCTGCTCGACGGATgtgtccagcagcagcagcagcagcagcaacaacagcaacaacaacaacaacaacagcgagcaaacgaacaacaacaacaatagcaacggggagcagcagcagcaactgctgctggcgtGCAAGCAGCGACGGCTGAAGAcgaacatcaacaacaacaacatcctcCTCAGCGACGAGGAGCAGCCAAAGCAGCCCAAGTCGGAGCCCGAGCCAGAGCCCGAaccggagccggagccagagCTGGACTCGGATGATGCGGATAGCGTGGATGTGGCACAGATGATCACGAGCACGCCGGATGTGGCCACATTGTTGGCAactggcggcggtggcggcagcACGCCGAGCCCCTCGCCGGGGTTGCAGAGCTGTCCGGCGTGCAATACCGGCGAGTTTGAGACATTGCCGGCACTGTGCGCGCATCTGGATGCAGCGCATCCGGACATACCGGCCAAGTGTCGCGACTGCGAGGTGATCTTTGGCAGCCATCGGCAGCTGCAGGCGCACAGTTGTCGCGgccagctgcagttgccgccgctgctcgGCGCGAGCAGCTCCCCACTGCACAAGCTGGAGGAGGAGCACGACCAGGAGCAGCACGAGCACGAGCAGGATCAGTATGcggatgaggaggaggaggaggtggaggAGGACGGGCAGCAGCGTGACGAGTTCTTTCAGCAGCTGTATCTGAAAGGTAAGGCCGGCGGCTTGCCGTCGCCCATCAAGCGTGAGCCAACGGAGCAGCGTCTGGAACAGCGTCAGGATCGTCAGGATCTGGCCGATATACAGAGCATTTTGCACAtgaccagctccagctgcacgTCGAGTTTCCTGCGCAACTTCGAGCAGTCCGTAAACACGCCCTGCTCCAGCCAGTACAGCCTGGACGGGCGCGACGGTGAGGAGGAGGCCCAGGATGCGTTCACCAGCGAATTCCGGCGGATGAAGCTGCGCGGCGAATTCCCCTGCAAGCTGTGCAGCGCCGTCTTTCCCAATCTGCGCGCCCTCAAGGGCCACAATCGCGTCCATCTGGCCGCCGTCGGCGCCGCCGGACCCTTCCGCTGCAACATGTGTCCCTACGCTGTCTGCGACAAGGCGGCCCTGGTGCGGCACATGCGCACCCACAACGGGGATCGGCCGTACGAGTGCGCCGTCTGCAATTACGCCTTCACCACGAAGGCCAACTGTGAGCGGCATCTGCGCAATCGACATGGCAAGACCAGCCGCGAGGAGGTGAAGCGCGCCATTGTCTATCATCCGGCGGAGGATGCCAGCTGCGAGGAGAACAACAAACGGGCGACGGGTCAGGACACCGACCTGGCCGAGCTCAGCTATCGTTCGCTGAGTCCGCCCCCTCCCCCGCTCCCGTTGCCACCATCGGCAGCGGAGTCGCAGCTGAAGCACATGTTGCTCGCGGAGCCGTGCGCCaagccgccgccaccgccgccgtcGGCGACGCAGGCGACGCCCCTAAAGATACAGGTGAAGAGCTTGGATCAGCTGGTGGAGAAGCCCCTCGCACCGCCAGCCATGGATCTCAGCATGGACGTGCTGGATCTGAGCAAGAAGCCCAcgcagcagctggagcgcCAGCGCGAGCGGGAGCGCGAACAGGAGCAcgagctgctccagctccagcagcaacaggtgcaacagctgcaacaggtgcagcagcagcagcagcagcagcagcagctgtttggAGGAGATGCGACGACGCAGTatatgcagcagctgctgcgcaatCTCATGTTCCAGCAGACGCCGGGCTTCTCCTTCTTTGGCTACATGGCGCCCCCGCcgtcggcggcggcaacggaTAAATCCCAAGCGAATCCCGCCCAGACGccggcaacagttgctgccatGCCCGTGCCCATGTCCTTGCCTGTGCCCGTGCCGGTTCCAGCTGGTGGACCCGTCAAGATGGTCATCAAGAACGGCGTCCTGATGCCCAAGCAGAAGCAGCGTCGCTACCGCACCGAGCGACCCTTCGCCTGCGAGCACTGCTCCGCCCGGTTCACGCTACGCTCCAACATGGAGCGCCATgtcaagcagcagcatcccCAGTACTATGCCCAGCGCCAGCGCAGCGGACACCATGTGATGCGCGGCCGTGCGGCTAGCTCCAAtgcggcggctgcggcagcggcagcggcggcagcagcagcagcagcagcagctgccatgtCGAAtctggcgcagcagcagcagcagcatgcgCATCCGCCCATCTCGGAGCAGGTGAAGTATGCGATATTGGCGCAGCAGCTGAAGGCGCGCAAGGATACGGatctgctgcagcaggcgctgGCGCACGGCTCCAGCAGCGCCCTGCTCCACtttaactacaacaacaacaacaacagcaacaccaacaacaagcagcagcagcagccacatccTATCAATGGAGTTGCTGCGGATGACGATGAGCCGCCCAAGCTGATCATAGACGAGGACGATGAGGTGGAGGAGGACGAGTTTGAGGATACGGAGGAGGAGCCCGAAGAGGAGCTCGAAATGGAGGAGGAAGACGAAGCGGAGGCGGCAGCCGAGCTGGAGCAGCTCGAGCAgcctgcggcggcggcagcggcggcgacgCCCACATTGCCACGCCCCGGCACGCCCATTGAGGCAGCCAAAAAGGTAGCGGAGAGCATACTGGAGCAGGTGATCAAGGCGCAGGCCAAGCCCGATCCGGACTCCGACGCCGTGGCCATGCCAACgccgacaacagcagcagcagccacgcccacaccgaCGCCGACTACGATGAAAACGATGATAGCCCAAGCGGAATCGGTGGCGAAATCCTTAAAGGATGTGGCCAGCTCGCCGTTCAAGGACGAATCTCAGGATCTGGTGCCGGTGGCCAAGCTGGTGGACAACGCGACCAGCAATCAGGTCTCCTTCAACAGCTATTTCCGGCCAAGCGATGTGGCCAACCACATGGAGCAGAGCGACGAGGAAGGCCTCGTCGCCTCCGGCAGCGCCAGCGAGAGCAACAATTCCGGCACCGAGGACgtgaccagcagcagctgcaacgaACCGAAGAAGAAGTCCGCCTACAGCCTGGCCCCGAATCGTGTCAGCTGTCCGTATTGCCAGCGCATGTTCCCGTGGAGCAGCTCGCTCCGGCGCCACATTCTCACCCATACGGGCCAGAAGCCCTTCAAGTGCTCCCACTGCCCGCTGCTGTTCACCACGAAGAGCAACTGCGATCGGCATCTGCTGCGCAAGCACGGCAATGTCGAGTCCGCGATGAGCGTCTATGTGCCCACCGAGGATGTCAGCGAGCCGATACCCGTGCCCAAGTCCGTCGAGGAGATCGCCCTCGAGGAGCAGCGCCGCCGCAAGGCAGCCGAGGCGGAGCGTGAAAGGGAGCGTGAACGTGAGCGCGAAAGAGAGCGGGAACGGGAGCGCGAACGGGAGCGAGaacgggagcgggagcagcagcTCATCCAGCAGCTGACCGCCGCGGCACAGCTGCGCCAGCAATtggccgccgcagccgccgtcgccgcagccggagcgggagcgggaaaTAGTCCAACAACTGGAGGCGCGGAGGGAAACGGCAGCGAGCTGCCGTACAAGTGTCATCTGTGCGAGTTCTCGTTCGGGGAGCGGCTGCAGTGCCTCGAGCACATCAAGCAGCTGCATGGCCAGGAGTTCGccctgctgctggccaaaggCGCCATCGAAACGGAGGCGCTccacgagcagcagcagcagcccaatcCTCAGCAGTCCACGCCCCTGGCAACAGCTGGCTCCGAGGACGAGTCGCTGGCACCGGCGGGTCGCGGCAATGGCAAATATCCGGACTACAGCAACCGGAAGGTGATATGCGCGTTTTGTGTGCGCCGCTTCTGGTCGACGGAGGATCTGCGTCGGCATATGCGCACACATTCCGGCGAACGGCCGTTCCAGTGCGAGATCTGTTTGCGCAAGTTCACGCTGAAGCACAGCATGCTGCGGCACATGAAGAAGCACAGCGGACGCAGTCACAATGGCGAGCAGGGCGCCTCCGATTGTTCCGATGACGAGCAGATGGCTACGCCACCAGGCACGCCCACTCCGACGCCCCAATCCATggccatgcccatgcccatgcccagcaacaacaacaacaacaacaacagttgccagaacaacaacaacaagcagagcCTGCGCCTGGTCCAGAAGGACAAAATGGGCGATGCCACGCcctcagcagcggcagcagccgccgccgcctttgGCATGGCCAGCGGCGATCTAATTGGCAATCTGCTGGGCATCAGCGACCAGGGCATACTCAACAAGCTGCTCTCCTCCGCGGACGAGGCGGCCAAGCTGCTGGGCGTGGAAAAGTAA
Protein Sequence: MLAAQQQQQPQQQHTAATATGGSTVGLADAGLERARRDSSTSESSLEHLDLSRTPKKLSSSSGAPQPTSTPHEATSRKRKLRQLQQPQQLLSDEDEEQLQQQQQQQQQQLLEQSAQRLRHKQRRSGNAAAVAAAAAASASIVVDYSAGGDASSLRKKFRLNRSSASSINGNNGELSESGFVDGSAHSGYLLSASSAAQSASAAQQQQQQQQQLASSSSSGGSSPQGLCHSSAESGIGAGDEHMKYVCPICEVVSATPHEFTNHIRCHNYANGDTENFTCRICSKVLSSASSLDRHVLVHTGERPFNCRYCHLTFTTNGNMHRHMRTHKQHQTTQQPTQQQTPQQQTPQQHAQQQHAPQQHAQHQQQRRQQHAGAAAGRAESYESDASCSTDVSSSSSSSSNNSNNNNNNSEQTNNNNNSNGEQQQQLLLACKQRRLKTNINNNNILLSDEEQPKQPKSEPEPEPEPEPEPELDSDDADSVDVAQMITSTPDVATLLATGGGGGSTPSPSPGLQSCPACNTGEFETLPALCAHLDAAHPDIPAKCRDCEVIFGSHRQLQAHSCRGQLQLPPLLGASSSPLHKLEEEHDQEQHEHEQDQYADEEEEEVEEDGQQRDEFFQQLYLKGKAGGLPSPIKREPTEQRLEQRQDRQDLADIQSILHMTSSSCTSSFLRNFEQSVNTPCSSQYSLDGRDGEEEAQDAFTSEFRRMKLRGEFPCKLCSAVFPNLRALKGHNRVHLAAVGAAGPFRCNMCPYAVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSREEVKRAIVYHPAEDASCEENNKRATGQDTDLAELSYRSLSPPPPPLPLPPSAAESQLKHMLLAEPCAKPPPPPPSATQATPLKIQVKSLDQLVEKPLAPPAMDLSMDVLDLSKKPTQQLERQREREREQEHELLQLQQQQVQQLQQVQQQQQQQQQLFGGDATTQYMQQLLRNLMFQQTPGFSFFGYMAPPPSAAATDKSQANPAQTPATVAAMPVPMSLPVPVPVPAGGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHVKQQHPQYYAQRQRSGHHVMRGRAASSNAAAAAAAAAAAAAAAAAAMSNLAQQQQQHAHPPISEQVKYAILAQQLKARKDTDLLQQALAHGSSSALLHFNYNNNNNSNTNNKQQQQPHPINGVAADDDEPPKLIIDEDDEVEEDEFEDTEEEPEEELEMEEEDEAEAAAELEQLEQPAAAAAAATPTLPRPGTPIEAAKKVAESILEQVIKAQAKPDPDSDAVAMPTPTTAAAATPTPTPTTMKTMIAQAESVAKSLKDVASSPFKDESQDLVPVAKLVDNATSNQVSFNSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSCNEPKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIALEEQRRRKAAEAEREREREREREREREREREREREREREQQLIQQLTAAAQLRQQLAAAAAVAAAGAGAGNSPTTGGAEGNGSELPYKCHLCEFSFGERLQCLEHIKQLHGQEFALLLAKGAIETEALHEQQQQPNPQQSTPLATAGSEDESLAPAGRGNGKYPDYSNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCEICLRKFTLKHSMLRHMKKHSGRSHNGEQGASDCSDDEQMATPPGTPTPTPQSMAMPMPMPSNNNNNNNSCQNNNNKQSLRLVQKDKMGDATPSAAAAAAAAFGMASGDLIGNLLGISDQGILNKLLSSADEAAKLLGVEK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00563368;
90% Identity: iTF_00617091; iTF_00563368; iTF_00526770;
80% Identity: -