Basic Information

Insect: Drosophila virilis
Gene Symbol: RREB1
Assembly: GCA_007989325.2
Location: CM017604.2:2327488-2339466[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 0.0051 0.3 11.3 0.6 1 21 245 265 245 267 0.96

2 13 0.00029 0.017 15.2 0.2 1 23 277 299 277 299 0.98

3 13 7e-05 0.0042 17.1 7.3 1 23 305 327 305 327 0.98

4 13 0.28 17 5.8 1.7 2 20 551 569 551 571 0.93

5 13 0.0077 0.46 10.7 0.1 1 23 714 736 714 736 0.97

6 13 1.1e-05 0.00064 19.7 0.7 1 23 746 768 746 768 0.99

7 13 0.00072 0.043 14.0 2.0 1 23 774 797 774 797 0.97

8 13 0.0026 0.15 12.2 2.0 1 23 1061 1084 1061 1084 0.95

9 13 7.5e-05 0.0045 17.1 0.3 2 23 1435 1456 1434 1456 0.97

10 13 0.13 7.5 6.9 6.3 1 23 1462 1485 1462 1485 0.97

11 13 8.2 4.8e+02 1.2 3.4 1 23 1602 1625 1602 1625 0.78

12 13 0.0073 0.44 10.8 0.5 3 23 1687 1707 1685 1707 0.96

13 13 0.0012 0.069 13.3 4.8 1 23 1713 1735 1713 1735 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	0.0051	0.3	11.3	0.6	1	21	245	265	245	267	0.96
2	13	0.00029	0.017	15.2	0.2	1	23	277	299	277	299	0.98
3	13	7e-05	0.0042	17.1	7.3	1	23	305	327	305	327	0.98
4	13	0.28	17	5.8	1.7	2	20	551	569	551	571	0.93
5	13	0.0077	0.46	10.7	0.1	1	23	714	736	714	736	0.97
6	13	1.1e-05	0.00064	19.7	0.7	1	23	746	768	746	768	0.99
7	13	0.00072	0.043	14.0	2.0	1	23	774	797	774	797	0.97
8	13	0.0026	0.15	12.2	2.0	1	23	1061	1084	1061	1084	0.95
9	13	7.5e-05	0.0045	17.1	0.3	2	23	1435	1456	1434	1456	0.97
10	13	0.13	7.5	6.9	6.3	1	23	1462	1485	1462	1485	0.97
11	13	8.2	4.8e+02	1.2	3.4	1	23	1602	1625	1602	1625	0.78
12	13	0.0073	0.44	10.8	0.5	3	23	1687	1707	1685	1707	0.96
13	13	0.0012	0.069	13.3	4.8	1	23	1713	1735	1713	1735	0.99

Sequence Information

Coding Sequence: atgctggccgcacagcaacagcagcagccacaacagcaacacacagcggcaacagcagcgggagGCACACAAGTAGGGCTCGAGGATGCGGGCTTGGAGCGGGCGCGCCGCGATTCGAGCACGTCGGAGTCCTCGCTGGAGCACCTCGACTTGAGCCGCACGCCAAAGaagctgagcagcagcagcggcgcgccgcagccgacgtcgacgccgcACGAGGCGACGTCGCGCAAGCGCAAACtgcgccagctgcagcagcagccgcaacagttGCTCTCCGACGAGGAtgaggagcagctgcagctgcagcagcagcaacagcagcagcagcagctgctggagcagTCCGCGCAGCGACTGCGGCACAAGCAGCGACGCAGCGGAAATGCAgtcgctgccgcagccgctgccagCGCCAGCATCGTCGTCGACTACAGCGCCGGCGGCGATGCCAGTTCGCTGCGCAAAAAGTTTCGCCTGAACCGCAGCAGCGCGAGCAGCATCAATGGCAACAACGGGGAGCTCTCCGAGTCTGGCTTTGTGGATGGGAGCGCGCACAGCGGCTATTTGCTCAGCGCCAGCAGCGCGGCGcagtcagcgtcagcgtcggcagcgcagcagcaacagcagcagcaattggccTCAAGCAGCAGCTCTGGCGGCAGCTCGCCCCAAGGCCTGTGCCACTCGAGCGCCGAGTCCGGCATTGGCGCCGGCGACGAGCACATGAAATATGTTTGCCCCATCTGCGAGGTCGTCTCGGCCACGCCCCACGAGTTCACCAATCACATACGTTGCCACAACTACGCCAACGGCGATACCGAGAACTTCACCTGCCGCATCTGCTCCAAGGTGCTATCATCCGCCTCCTCGCTGGACAGACACGTGCTGGTGCACACGGGCGAGCGTCCGTTCAACTGTCGCTATTGCCATCTGACATTCACGACGAACGGCAACATGCACCGGCACATGCGCACCCACAAGCAGCACCAgacgacgcagcagcagcagccgacgcagcagcagcagcaacagacacagcagcaacatgcacCGCAGCAAcatgcacagcagcaacatgcacagcagcagcagcgacggcagcaACATGCGGGCGCGGCAGCTGGGCGCGCTGAAAGCTACGAGAGCGATGCCAGCTGCTCGACGGATgtgtccagcagcagcagtgccagcagcagcaacaacagcaacaataacaacaacaacaacaacaacaacagcgagcaaacgaacaagaacaacagcaacagcaacggtgagcataagcagcagcagcagcaactgttgctggcgTGCAAGCAGCGAAGGCCGAAGacgaacatcaacaacaacaacattctcAGCGACGAGGAGCAGCCAAAGCAGCCCAAGTCGGAGCCCGAGCCGGAGCTCGAACCGGAGCCAGAGCTGGActcggatgcggatgcggatgcggagaGCGTGGATGTGGCACAAATGATCACGAGCACGCCGGATGTGGCCACATTGTTGGCcaccggcggcggcggcggcagcacgcCCAGTCCCTCGCCGGGACTGCAGAGCTGTCCGGCATGTAATACGGGCGAATTTGAGACATTGCCGGCGCTGTGCGCGCATCTGGATGCAGCGCATCCGGACATACCAGCCAAGTGTCGCGAATGTGAGGTGATCTTTGCCAGCCATCGGCAGCTGCAGGCGCACAGCTGTCgcggccagctgcagctgccgccgctgctcgGCGCCAGCAGCTCCCCGCTGCACAAGCTGGAGGAGCACGAGCACGACCAGGAGCagcacgagcagcagcagtatgcggatgaggaggaggaggaggaggagcaatTGGCCAGCAGCGAACGGGACGAGTTCTTTCAGCAGCTCTATCTGAAAGGCAAGGCCGGCGGCCTGCCGTCGCCCATCAAGCGGGAGCCATCGGAGCAGCGTCAGGATCTGGCCGATATACAAAGCATACTGCACATGACCAGCTCCAGCTGTACGTCAAGTTTCCTGCGCAACTTCGAGCAGTCCGTAAACACGCCCTGCTCCAGCCAGTACAGTCTGGATGGGCGCGACGGCGAGGAGGAGGCCCAAGATGCGTTCACCAGCGAATTTCGGCGCATGAAACTGCGCGGCGAATTCCCCTGCAAACTGTGCAGCGCCGTCTTTCCCAATCTGCGCGCCCTCAAGGGCCACAATCGTGTCCATCTGGCCGCTGTCGGCGCCGCCGGACCCTTTCGCTGCAACATGTGCCCATATGCCGTTTGCGACAAGGCGGCGCTGGTGCGGCACATGCGCACCCACAACGGAGATCGGCCGTACGAGTGTGCCGTGTGCAATTATGCATTCACCACGAAGGCCAACTGTGAGCGGCATCTGCGCAATCGACATGGCAAGACGAGCCGCGAGGAGGTCAAGCGCGCCATTGTCTATCATCCGGCGGAGGATGCCAGCTGCGAGGAGAATAACAAACGGGCCGCGGGCCAGGACACGGATCTGGCCGAGCTTAGCTATCGCTCGCTCAGCCCGCCACCGCCGCTTCCGCTTCCTTTGCCGCCGCCGGCGACAGAGTCGCAGCTGAAGCACATGTTGCTCGCCGAGCCGTGCACCAAACCGCCGTTGCCGACGCCGGCGACGCCGCTCAAGATACAGGTGAAGAGCTTGGATCAGCTGGTGGAGAAACCGCCAGCGCCGCCGGCCATGGATCTCAGCATGGATGTGCTGGATCTGAGCAAGAAGCCCACACAGCAGCTGGAGCGCCAGCGCGAACGGGAACGCGAACGCGAACAGGAGCACGAGCTGCTccagctacagcagcaacaggtgcAACAggtgcaacagctgcaacaggtgcaacagcagcagcagcagcagctgtttggTGGCGATGCGACCACGCAATATATGCAGCAATTGCTGCGCAATCTCATGTTCCAGCAGACGCCGGGCTTCTCATTCTTCAGCTATATGGCGCCTCCGCcgccggcaacggcaacaacagcaacagataaATCGCAAGCGAATGCAGCTGCGACGccggcaacagttgctgccatGCCCGTGCCCATGCCCATGGCCGTGCCAGTGCCCGTGCCAGCGGGCGGACCCGTCAAGATGGTCATCAAGAACGGCGTCCTGATGCCCAAGCAGAAGCAGCGTCGCTATCGCACCGAGCGTCCCTTCGCCTGCGAGCACTGCTCCGCCCGTTTCACGCTGCGCTCCAACATGGAGCGACATGTTAAGCAGCAGCATCCCCAGTACTATGCACAGCGCCAGCGCAGCGGACACCATGTGATGCGCGGACGCGCGGCCAGCTCAaatgcggcggcggcggcggcagcggcagcggcggcagcagcagcagcagctgccatgtCGAAtctggcgcagcagcagcagcagcagcaacagcagcatgcGCATCCGCCCATCTCGGAGCAGGTGAAGTATGCGATATTGGCGCAACAGCTGAAGGCGCGCAAGGATACGGATCTGTTGCAGCAGGCGCTGGCGCATGGCTCAAGCAGCGCGCTGCTCCActtcaactacaacaacaacaacaacaacaagcaggagcagcagcagcagcagccacatccCGGCAACAACCAGAACGGAGCTGCTGCGGACGACGATGAGCCGCCCAAGCTGATCATAGACGAGGACGATGAGGTTGAGGAGGAGGAGTTTGACGATACGGATGAAGAGCCGGAGGAGGAGCTCGAAATGGAGGAGGATGACGAGGAGCAGGCGGAACAGCTCGTGGAGCCCGCGACGGCGGCAACGCCCACATTGCAACGCCCCGGCACACCAATTGAGGCAGCCAAAAAGGTAGCGGAGAGCATACTGGAGCAGGTGATCAAGGCGCAGGCCAAGCCCGATCCCGATCCCGAATCTGATGCTGTGGCCATGCCAACGCccacaactgcagcagcagcagcagcagcagcagcagcagtagcagccacgcccacgcccactaCGATGAAAACAATGATAGCCCAAGCAGAATCGGTGGCCAAATCCTTGAAAGATGTGGCCAGTTCGCCGTTCAAGGACGAATCTCAGGATCTGGTGCCGGTGGCCAAGCTGGTGGACAACGCGACCAGCAATCAGGTCTCCTTCAACAGCTATTTCCGGCCAAGCGACGTGGCCAATCATATGGAACAGAGCGACGAGGAGGGCCTAGTCGCCTCCGGCAGCGCCAGCGAGAGCAACAATTCCGGCACCGAGGACgtgaccagcagcagctgcaacgaaCCGAAAAAGAAGTCCGCCTACAGTCTGGCACCGAATCGTGTCAGCTGCCCGTATTGCCAGCGCATGTTCCCGTGGAGCAGCTCGCTCCGGCGCCACATTCTCACCCATACGGGCCAAAAGCCCTTCAAGTGCTCCCATTGCCCGCTGCTGTTCACCACGAAGAGCAACTGCGATCGGCATCTGTTGCGCAAGCACGGCAATGTCGAGTCCGCAATGAGCGTCTATGTGCCCACCGAGGATGTCAGCGAACCGATACCCGTGCCCAAGTCCGTTGAAGAGATCGCCTTGGAGGAGCAGCGACGCCGCAAGGCAGCCGAGGCGGAGCGCGAAAGGGAGCGCGAAAGGGAACGGGAACGTGAACGCGAGCGGGAACGCGAAAGAGAGCGTGAAAGGGaacgggagcagcagcagcagctcatccaGCAGCTGACGGCCGCGGCACAGCTGCGCCAGCAActggccgccgctgccgccgttgccgcAGCTGGAGCCGGAGCTGGAAATAGTCCAACTGGAGGGGAGGGTAACGGCAGTGAGCTGCCGTACAAATGTCATCTATGCGAGTTCTCGTTCGGCGAGCGGCTGCAGTGCCTCGAGCACATCAAGCAGCTGCATGGCCAGGAGTTTGCCCTGCTGTTGGCCAAGGGCGCCATCGAAACGGAGGCGCTCCACGACCAACAGCTGCCCAATcctcagcaacagcagcccctGGCAACAGCTGGCTCCGAGGATGAATCGCTGGCGCCGGCGGGTCGCGGCAATGGCAAATATCCGGACTACAGCAATCGGAAGGTGATCTGTGCGTTCTGTGTGCGTCGCTTCTGGTCCACGGAGGATTTGCGGCGACATATGCGCACACATTCCGGCGAAAGGCCGTTCCAGTGCGAGATCTGTTTGCGCAAGTTCACGCTGAAGCACAGCATGCTGCGCCACATGAAGAAGCACAGCGGACGCAGTCACAATGGCGAGCAGGGCGCCTCCGACTGTTCCGATGACGAGCAGATGGCCACGCCACCCGGCACGCCCACTCCAACGCCCCAATCCATGGCCATGCCcagtaataataacaacaacaacaacaacaacagttgccagaacaacaacaacaagcagagcCTGCGCCTGGACAAGACGCCCGACTGGCGCCTCCAGAAGGATAAAATGGGTGATGCCACGCCCTCAgctggaggagcagcagccgccgccgccgccgcctttgGCATGGCCAGCGGCGATCTAATTGGCAATCTGCTGGGCATCAGCGACCAGGGCATACTCAACAAGCTGCTCTCCTCCGCGGACGAGGCGGCCAAGCTGCTGGGCGTGGAAAAGTAA
Protein Sequence: MLAAQQQQQPQQQHTAATAAGGTQVGLEDAGLERARRDSSTSESSLEHLDLSRTPKKLSSSSGAPQPTSTPHEATSRKRKLRQLQQQPQQLLSDEDEEQLQLQQQQQQQQQLLEQSAQRLRHKQRRSGNAVAAAAAASASIVVDYSAGGDASSLRKKFRLNRSSASSINGNNGELSESGFVDGSAHSGYLLSASSAAQSASASAAQQQQQQQLASSSSSGGSSPQGLCHSSAESGIGAGDEHMKYVCPICEVVSATPHEFTNHIRCHNYANGDTENFTCRICSKVLSSASSLDRHVLVHTGERPFNCRYCHLTFTTNGNMHRHMRTHKQHQTTQQQQPTQQQQQQTQQQHAPQQHAQQQHAQQQQRRQQHAGAAAGRAESYESDASCSTDVSSSSSASSSNNSNNNNNNNNNNSEQTNKNNSNSNGEHKQQQQQLLLACKQRRPKTNINNNNILSDEEQPKQPKSEPEPELEPEPELDSDADADAESVDVAQMITSTPDVATLLATGGGGGSTPSPSPGLQSCPACNTGEFETLPALCAHLDAAHPDIPAKCRECEVIFASHRQLQAHSCRGQLQLPPLLGASSSPLHKLEEHEHDQEQHEQQQYADEEEEEEEQLASSERDEFFQQLYLKGKAGGLPSPIKREPSEQRQDLADIQSILHMTSSSCTSSFLRNFEQSVNTPCSSQYSLDGRDGEEEAQDAFTSEFRRMKLRGEFPCKLCSAVFPNLRALKGHNRVHLAAVGAAGPFRCNMCPYAVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSREEVKRAIVYHPAEDASCEENNKRAAGQDTDLAELSYRSLSPPPPLPLPLPPPATESQLKHMLLAEPCTKPPLPTPATPLKIQVKSLDQLVEKPPAPPAMDLSMDVLDLSKKPTQQLERQREREREREQEHELLQLQQQQVQQVQQLQQVQQQQQQQLFGGDATTQYMQQLLRNLMFQQTPGFSFFSYMAPPPPATATTATDKSQANAAATPATVAAMPVPMPMAVPVPVPAGGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHVKQQHPQYYAQRQRSGHHVMRGRAASSNAAAAAAAAAAAAAAAAAMSNLAQQQQQQQQQHAHPPISEQVKYAILAQQLKARKDTDLLQQALAHGSSSALLHFNYNNNNNNKQEQQQQQPHPGNNQNGAAADDDEPPKLIIDEDDEVEEEEFDDTDEEPEEELEMEEDDEEQAEQLVEPATAATPTLQRPGTPIEAAKKVAESILEQVIKAQAKPDPDPESDAVAMPTPTTAAAAAAAAAAVAATPTPTTMKTMIAQAESVAKSLKDVASSPFKDESQDLVPVAKLVDNATSNQVSFNSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSCNEPKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIALEEQRRRKAAEAEREREREREREREREREREREREREREQQQQLIQQLTAAAQLRQQLAAAAAVAAAGAGAGNSPTGGEGNGSELPYKCHLCEFSFGERLQCLEHIKQLHGQEFALLLAKGAIETEALHDQQLPNPQQQQPLATAGSEDESLAPAGRGNGKYPDYSNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCEICLRKFTLKHSMLRHMKKHSGRSHNGEQGASDCSDDEQMATPPGTPTPTPQSMAMPSNNNNNNNNNSCQNNNNKQSLRLDKTPDWRLQKDKMGDATPSAGGAAAAAAAAFGMASGDLIGNLLGISDQGILNKLLSSADEAAKLLGVEK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00563368;
90% Identity: iTF_00506310;
80% Identity: -