Basic Information

Insect: Drosophila kanekoi
Gene Symbol: RREB1
Assembly: GCA_037075305.1
Location: JBAMCE010000484.1:1298549-1304830[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 0.006 0.4 11.3 0.6 1 21 241 261 241 263 0.96

2 13 0.00034 0.023 15.2 0.2 1 23 273 295 273 295 0.98

3 13 8.3e-05 0.0055 17.2 7.3 1 23 301 323 301 323 0.98

4 13 0.24 16 6.3 1.7 2 20 537 555 537 557 0.93

5 13 0.0091 0.6 10.7 0.1 1 23 709 731 709 731 0.97

6 13 1.3e-05 0.00084 19.7 0.7 1 23 741 763 741 763 0.99

7 13 0.00085 0.056 14.0 2.0 1 23 769 792 769 792 0.97

8 13 0.003 0.2 12.2 2.0 1 23 1048 1071 1048 1071 0.95

9 13 8.9e-05 0.0059 17.1 0.3 2 23 1418 1439 1417 1439 0.97

10 13 0.15 9.8 6.9 6.3 1 23 1445 1468 1445 1468 0.97

11 13 9.6 6.4e+02 1.2 3.4 1 23 1587 1610 1587 1610 0.78

12 13 0.0086 0.57 10.8 0.5 3 23 1671 1691 1669 1691 0.96

13 13 0.0014 0.091 13.3 4.8 1 23 1697 1719 1697 1719 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	0.006	0.4	11.3	0.6	1	21	241	261	241	263	0.96
2	13	0.00034	0.023	15.2	0.2	1	23	273	295	273	295	0.98
3	13	8.3e-05	0.0055	17.2	7.3	1	23	301	323	301	323	0.98
4	13	0.24	16	6.3	1.7	2	20	537	555	537	557	0.93
5	13	0.0091	0.6	10.7	0.1	1	23	709	731	709	731	0.97
6	13	1.3e-05	0.00084	19.7	0.7	1	23	741	763	741	763	0.99
7	13	0.00085	0.056	14.0	2.0	1	23	769	792	769	792	0.97
8	13	0.003	0.2	12.2	2.0	1	23	1048	1071	1048	1071	0.95
9	13	8.9e-05	0.0059	17.1	0.3	2	23	1418	1439	1417	1439	0.97
10	13	0.15	9.8	6.9	6.3	1	23	1445	1468	1445	1468	0.97
11	13	9.6	6.4e+02	1.2	3.4	1	23	1587	1610	1587	1610	0.78
12	13	0.0086	0.57	10.8	0.5	3	23	1671	1691	1669	1691	0.96
13	13	0.0014	0.091	13.3	4.8	1	23	1697	1719	1697	1719	0.99

Sequence Information

Coding Sequence: atgctggccgcacagcagcagcagccacaacagcaacacacagcggcaacagcaacgggagAGAGCACAGTAGGGCTTGAGGATGCGAGCTTGGAGCGAGCAAGACGCGACTCAAGCACGTCGGAGTCCTCGCTGGAGCACCTGGACTTGAGCCGCACGCCAAAgaagctgagcagcagcagcggcgcgcCGCAGCCGACGTCAACGCCGCACGAGGCGACATCACGCAAGCGCAAGCtacgccagctgcagcagccgcaacagttGCTCtccgatgaggatgaggagcagctgcagcagcagcagcaacagcagcagctgctggagcagtccacgcagcgactgcggcacAAGCAGCGACGCAGCGGAAAtgcagccgcagtcgccgccgccgccgctgccagcgcCAGCATCGTGGTCGACTACAGCGCCGGCGGCGATGCCAGTTCGCTGCGCAAAAAGTTTCGCCTGAACCGCAGCAGCGCGAGCAGCATCAATGGCAACAACGGGGAGCTCTCCGAGTCCGGCTTTGTGGATGGCAGCGCGCACAGCGGCTATTTGctcagcgccagcagcgcgGCGCAGTCAGCGtcggcagcgcagcagcagcaacagcagcagcaattggccTCAAGTAGCAGCTCCGGCGGCAGCTCGCCCCAAGGCCTGTGCCACTCAAGCGCCGAGTCCGGCATCGGCGCCGGCGACGAGCACATGAAATATGTTTGCCCCATCTGCGAGGTCGTCTCGGCCACGCCCCACGAGTTCACCAATCACATACGCTGCCACAACTACGCCAACGGCGACACCGAGAACTTCACCTGCCGCATCTGCTCCAAGGTGCTGTCATCCGCCTCCTCGCTGGACAGGCACGTGCTGGTGCACACGGGCGAGCGTCCGTTCAACTGTCGCTATTGCCATTTGACATTCACGACGAACGGCAACATGCACCGGCACATGCGGACCCACAAGCAGCACCAgacgacgcagcagcagcagccgacgcagcagcagcagcaacagacacCGCAGCAacatgcacagcagcaacatgcacCGCAGCAacatgcacagcagcagcagcagcagcgacgccagcaacATGCGGGCGCGGCAGCTGGACGCGCGGAGAGCTACGAGAGCGATGCCAGCTGCTCGACGGATgtgtccagcagcagcagcagcagcaacaacagcaacaatagcaacaacaacaacaacaacagcgagcaaacgaacaagaacaacagcaacggggagcagcagcagcaactgttgctggcgTGCAAGCAACGACGGCCAAAGAcgaacatcaacaacaacaacatcctcAGCGACGAGGAGCAGCCAAAGCAGCCAAAATCGGAGCCGGAGGCAGAGCCCGAAGCAGAGCCAGAACCGGACTCGGATGATGCAGAGAGCGTGGATGTGGCACAGATGATCACGAGCACGCCGGATGTTGCCACATTGTTGGCCACCGGCGGGGGCGGCAGCACGCCCAGCCCCTCGCCGGGGCTGCAGAGCTGTCCGGCGTGCAATACGGGCGAGTTTGAGACATTGCCGGCGCTGTGCGCGCATCTGGATGCAGCGCATCCCGATATACCAGCCAAGTGTCGCGACTGCGAGGTGATCTTTGCCAGCCATCGGCAGCTGCAGGCGCACAGCTGTCgcggccagctgcagctgccgccgcttcTAGGCGCGAGCAGCTCGCCCCTGCACAAGCTTGAGGAGGACCATGACCTGGACCACGAGCAGCACGATCAGGAGCAGTATGCagatgaggaggaggaagaggacggccagcagctgcccaGCAGCGAGCGGGACGAGTTCTTTCAGCAGCTCTATCTGAAAGGCAAGGCTGGAGGGTTGCCGTCGCCCATCAAGCGGGAGCCATCGGAGCAGCGTCTGGAGCAGCGTCAGGATCGTCAGGATCTGGCCGATATACAGAGCATTCTGCACAtgaccagctccagctgcacctCGAGTTTCCTGCGCAACTTTGAGCAGTCCGTGAACACCCCTTGCTCCAGCCAGTATAGCCTGGACGGGCGCGACGGCGAGGAGGAGGCGCAGGATGCGTTTACCAGCGAATTCCGGCGGATGAAATTGCGCGGCGAATTCCCCTGCAAGCTGTGCAGCGCCGTCTTTCCCAATCTGCGCGCCCTCAAGGGCCACAATCGCGTCCATCTGGCCGCTGTCGGCGCCGCGGGACCCTTCCGCTGCAACATGTGTCCCTATGCCGTATGCGACAAGGCGGCGCTGGTGCGGCACATGCGCACCCACAATGGGGATCGGCCATACGAGTGCGCCGTCTGCAACTACGCCTTCACCACGAAGGCCAACTGTGAGCGGCATCTGCGCAATCGGCACGGCAAGACGAGCCGCGAGGAGGTGAAGCGCGCCATTGTCTATCATCCGGCAGAGGATGCCAGCTGCGAGGAGGGCAGCAAACGGGCTACGGGCCAGGACACGGACCTGGCCGAGCTCAGCTATCGCTCGCTCagtccgccgccgccgctcaCACTCCCGTTGCCCCCGCCGTCGGCAGCGGAGTCGCAGCTGAAGCACATGTTGCTCGCGGAGCCGTGCAccaagccgccgccgcctccaccGCCGCCAGCAACGCCGCTCAAGATACAGGTGAAGAGCTTGGATCAGCTGGTGGAGAAGCCCCAAGCGCCGCCAGCCATGGATCTCAGCATGGACGTGCTGGACTTGAGCAAGAAGCCcacgcagcagctggagcgccAGCGCGAACGTGAGCGCGAACAGGAGcacgagctgctgctccagcagcaacaggtgcaacagctgcaacaggtgcaacagcagcaacagcagctgtttggGGGAGATGCGACGACGCAGtatatgcagctgctgcgcaatCTAATGTTACAGCAGACGCAGGGCTTCTCCTTCTTTGGCTATATGGCGCCCCCGCCGCCGGCGGCCTCAACGGATACACCCCAGCCAGGCACAAATCCAGCCCAGACGCCGGCCACAGTGGCTGCCATGCCCATGTCCGTGCCTGTGCCGGTACCGGTGCCAGCGGGTGGGCCCGTCAAGATGGTCATCAAGAACGGCGTCCTCATGCCCAAGCAGAAGCAGCGTCGCTACCGCACCGAGCGACCCTTCGCCTGCGAGCACTGCTCCGCCCGCTTCACGCTGCGCTCCAACATGGAGCGCCATgtcaagcagcagcatccCCAGTACTATGCGCAGCGCCAGCGCAGCGGACATCACGTGATGCGCGGCCGTGCCGCCAGCTCCAATgcggcagctgcggcggcggcagcggcagcagcagcagcagcagccgctgccatGTCGAAtctggcgcagcagcagcagcagcagcagcatgcgcATCCGCCCATCTCGGAGCAGGTGAAGTATGCGATATTggcgcagcagctgaaggCGCGCAAGGACACGGatctgctgcagcaggcgctggCACACGGCTCCAGCAGCGCGCTGCTCCActtcaactacaacaacaacaacaacaacaagcagcagcaacagcagcagccacatccCGTGAACAACCTGAATGGAGCTGCTGCGGATGATGATGAGCCGCCCAAGCTGATTATAGACGAGGATGACGAGGAGGAAGACTTTGAGGATACGGAGGAGGAGCCGGAGGAGGAGCTCGAAATGGAGGAGGACGATGAGGAGCAGGCGTCGGGCGAGCTGGAGCAGCTCGAGCAgcctgcggcggcggcgccggcgTTGCCACGCCCCGGCACGCCCATTGAGGCAGCCAAAAAGGTAGCAGAGAGCATATTGGAGCAGGTGATCAAGGCGCAGGCCAAGCCCGATCCGGAGTCAGATGCCGTGGCCATGCCAACGCCCACGACAtcagcagccacgcccacaccgaCACCCACAGCGACGCCCACACCGACGCCGACAACAATGAAAACGATGATAGCCCAAGCGGAATCGGTGGCCAAATCCTTGAAAGATGTGGCCAGCTCGCCGTTCAAGGACGAATCTCAGGATCTGGTGCCGGTGGCCAAGCTGGTGGACAACGCGACCAGCAATCAGGTCTCCTTCAACAGCTATTTTCGGCCGAGCGATGTGGCCAATCACATGGAGCAGAGCGACGAGGAGGGCCTGGTCGCCTCCGGCAGCGCCAGCGAGAGCAACAACTCCGGCACCGAGGAcgtgaccagcagcagctgcaacgaGCCGAAGAAGAAGTCCGCATATAGTCTGGCCCCGAATCGTGTCAGCTGTCCGTATTGCCAGCGCATGTTCCCGTGGAGCAGCTCGCTTCGTCGGCACATTCTCACCCACACGGGCCAGAAGCCCTTCAAGTGCTCCCACTGCCCACTGCTGTTCACCACGAAGAGCAACTGCGACCGGCATCTGTTGCGCAAGCACGGCAATGTCGAGTCCGCGATGAGCGTCTATGTGCCCACCGAGGATGTCAGCGAGCCGATACCCGTGCCCAAGTCCGTCGAGGAGATCGCCTTAGAGGAGCAGCGCCGCCGCAAAGCCGCCGAGGCGGAGCGCGAACGCGAAcgccagctggagctggagcgggAGCGCGAAAGGGAGCGGGAACGCAAGCTCGAACGCGaacgggagcagcagcagcagctaatccAACAACTAACGGCTGCGGCACAACTACGCCATCAACtggctgcagccgctgccgtcgccgcaGCCGGAGTCGGAGCCGGGAATAGTCCAACAACTGGGAGCGGGGAGGCGAACGGCAGCGAGCTGCCCTACAAATGCCATCTGTGCGAATTCTCGTTCGGGGAGCGGCTGCAGTGCCTCGAGCACATCAAGCAGCTGCATGGCCAGGAGTTCGCCCTGCTGCTCGCCAAAGGCGCCATCGAAACGGAGGCGCTtcacgagcagcagcagcccaatcCTCAGACCACGCCCATGGCAACAGCTGGCTCCGAGGATGAGTCGCTGGCGCCGGCGGGTCGCGGCAATGGCAAATATCCGGACTACAGCAACCGGAAGGTGATCTGCGCGTTTTGCGTGCGCCGTTTCTGGTCCACCGAGGATCTGCGTCGACATATGCGCACGCATTCCGGCGAACGGCCGTTCCAGTGCGAGATCTGTTTGCGCAAGTTCACGCTGAAGCACAGCATGCTGCGGCACATGAAGAAGCACAGTGGACGCAGTCACAATGGCGAGCAGGGCGCCTCCGACTGTTCCGATGACGAGCAGATGGCCACGCCGCCCGGCACGCCCACCCCTACGCCCACGCCCATGGCCATGCCCATGcctagcagcaacaacaacaacaacaacagcacttgccagaacaacaacaacaacaacaacaagcagagcCTGCGCCTAGACAAGGCGCCCGAATGGCGCCTGCAGAAGGACAAAATGGGCGATGCCACGCcctcagctgcagcagccgccgccttTGGCATGGCCAGCGGCGATCTGATTGGCAATCTGCTGGGCATCAGCGACCAGGGCATACTCAACAAGCTGCTCTCCTCCGCGGACGAGGCGGCCAAGCTGCTGGGCGTGGAAAAGTAA
Protein Sequence: MLAAQQQQPQQQHTAATATGESTVGLEDASLERARRDSSTSESSLEHLDLSRTPKKLSSSSGAPQPTSTPHEATSRKRKLRQLQQPQQLLSDEDEEQLQQQQQQQQLLEQSTQRLRHKQRRSGNAAAVAAAAAASASIVVDYSAGGDASSLRKKFRLNRSSASSINGNNGELSESGFVDGSAHSGYLLSASSAAQSASAAQQQQQQQQLASSSSSGGSSPQGLCHSSAESGIGAGDEHMKYVCPICEVVSATPHEFTNHIRCHNYANGDTENFTCRICSKVLSSASSLDRHVLVHTGERPFNCRYCHLTFTTNGNMHRHMRTHKQHQTTQQQQPTQQQQQQTPQQHAQQQHAPQQHAQQQQQQRRQQHAGAAAGRAESYESDASCSTDVSSSSSSSNNSNNSNNNNNNSEQTNKNNSNGEQQQQLLLACKQRRPKTNINNNNILSDEEQPKQPKSEPEAEPEAEPEPDSDDAESVDVAQMITSTPDVATLLATGGGGSTPSPSPGLQSCPACNTGEFETLPALCAHLDAAHPDIPAKCRDCEVIFASHRQLQAHSCRGQLQLPPLLGASSSPLHKLEEDHDLDHEQHDQEQYADEEEEEDGQQLPSSERDEFFQQLYLKGKAGGLPSPIKREPSEQRLEQRQDRQDLADIQSILHMTSSSCTSSFLRNFEQSVNTPCSSQYSLDGRDGEEEAQDAFTSEFRRMKLRGEFPCKLCSAVFPNLRALKGHNRVHLAAVGAAGPFRCNMCPYAVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSREEVKRAIVYHPAEDASCEEGSKRATGQDTDLAELSYRSLSPPPPLTLPLPPPSAAESQLKHMLLAEPCTKPPPPPPPPATPLKIQVKSLDQLVEKPQAPPAMDLSMDVLDLSKKPTQQLERQREREREQEHELLLQQQQVQQLQQVQQQQQQLFGGDATTQYMQLLRNLMLQQTQGFSFFGYMAPPPPAASTDTPQPGTNPAQTPATVAAMPMSVPVPVPVPAGGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHVKQQHPQYYAQRQRSGHHVMRGRAASSNAAAAAAAAAAAAAAAAAMSNLAQQQQQQQHAHPPISEQVKYAILAQQLKARKDTDLLQQALAHGSSSALLHFNYNNNNNNKQQQQQQPHPVNNLNGAAADDDEPPKLIIDEDDEEEDFEDTEEEPEEELEMEEDDEEQASGELEQLEQPAAAAPALPRPGTPIEAAKKVAESILEQVIKAQAKPDPESDAVAMPTPTTSAATPTPTPTATPTPTPTTMKTMIAQAESVAKSLKDVASSPFKDESQDLVPVAKLVDNATSNQVSFNSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSCNEPKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIALEEQRRRKAAEAERERERQLELERERERERERKLEREREQQQQLIQQLTAAAQLRHQLAAAAAVAAAGVGAGNSPTTGSGEANGSELPYKCHLCEFSFGERLQCLEHIKQLHGQEFALLLAKGAIETEALHEQQQPNPQTTPMATAGSEDESLAPAGRGNGKYPDYSNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCEICLRKFTLKHSMLRHMKKHSGRSHNGEQGASDCSDDEQMATPPGTPTPTPTPMAMPMPSSNNNNNNSTCQNNNNNNNKQSLRLDKAPEWRLQKDKMGDATPSAAAAAAFGMASGDLIGNLLGISDQGILNKLLSSADEAAKLLGVEK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00563368;
90% Identity: iTF_00506310;
80% Identity: -