Basic Information

Insect: Drosophila emarginata
Gene Symbol: -
Assembly: GCA_037075365.1
Location: JBAMCD010000106.1:1252463-1255611[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 0.00017 0.015 16.1 4.6 1 23 199 222 199 222 0.97

2 16 0.00017 0.015 16.1 2.7 1 23 251 274 251 274 0.97

3 16 0.0015 0.13 13.2 3.2 1 23 326 349 326 349 0.96

4 16 0.097 8.5 7.4 1.5 2 21 403 422 402 424 0.94

5 16 0.95 83 4.3 1.5 1 20 542 561 542 563 0.81

6 16 0.016 1.4 9.9 1.3 1 23 572 594 572 594 0.94

7 16 9.4e-05 0.0082 16.9 0.8 1 23 601 624 601 624 0.96

8 16 0.00024 0.021 15.6 0.9 2 23 633 654 632 654 0.96

9 16 0.00042 0.037 14.9 0.1 2 22 681 701 680 704 0.90

10 16 0.12 10 7.1 0.8 1 23 740 763 740 763 0.96

11 16 8.8 7.7e+02 1.3 0.4 3 21 772 790 770 791 0.90

12 16 0.012 1 10.3 1.4 1 23 800 823 800 823 0.95

13 16 1.7e-05 0.0015 19.3 0.5 1 23 850 873 850 873 0.97

14 16 0.24 21 6.2 0.2 1 23 883 905 883 905 0.93

15 16 6.7e-05 0.0059 17.4 3.7 1 23 911 933 911 933 0.99

16 16 6.9e-06 0.00061 20.5 3.2 1 23 939 961 939 961 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	0.00017	0.015	16.1	4.6	1	23	199	222	199	222	0.97
2	16	0.00017	0.015	16.1	2.7	1	23	251	274	251	274	0.97
3	16	0.0015	0.13	13.2	3.2	1	23	326	349	326	349	0.96
4	16	0.097	8.5	7.4	1.5	2	21	403	422	402	424	0.94
5	16	0.95	83	4.3	1.5	1	20	542	561	542	563	0.81
6	16	0.016	1.4	9.9	1.3	1	23	572	594	572	594	0.94
7	16	9.4e-05	0.0082	16.9	0.8	1	23	601	624	601	624	0.96
8	16	0.00024	0.021	15.6	0.9	2	23	633	654	632	654	0.96
9	16	0.00042	0.037	14.9	0.1	2	22	681	701	680	704	0.90
10	16	0.12	10	7.1	0.8	1	23	740	763	740	763	0.96
11	16	8.8	7.7e+02	1.3	0.4	3	21	772	790	770	791	0.90
12	16	0.012	1	10.3	1.4	1	23	800	823	800	823	0.95
13	16	1.7e-05	0.0015	19.3	0.5	1	23	850	873	850	873	0.97
14	16	0.24	21	6.2	0.2	1	23	883	905	883	905	0.93
15	16	6.7e-05	0.0059	17.4	3.7	1	23	911	933	911	933	0.99
16	16	6.9e-06	0.00061	20.5	3.2	1	23	939	961	939	961	0.98

Sequence Information

Coding Sequence: atgCCAAGAACCTGCCGTATTTGCGCTGGAGATGGGGGACGATTTTGGATCGAGACGCCTGTAGAGAAGTATGCTGGGAAAACGTTCAATCAGTTGCTTCTAGATCTGACCAAAATTGAACTGACCATGGACCAGATGGAGAAGCTAACGCCCTGGATATGCCGCAATTGTGCGCATAAATTGCAGCGTTCTTATGACTTTGTTTTAAAGGCTAAAAGGACGCACGAGATTCTGGTAGATAGATTGATGGAGTCAATGGCTGTGGCCAAATCCCATGTGGTGCTAGAAGAGGAAGATCCATTTTGCCTACGTGAGACTCCCATACAGTTGATGGAGATTGAGGGAGTGACTATTAAAATGGAAGATTCTGAGCCAAGTACTATTATTACTGGTGATAATACTGGGCCGCCGTATACTGTGCCTGATCCTCTAGTCCGTGAAGGGGTTGAGAAGCGTGCCATTTCAGACTTAAGCGAAGCCGAAGATAACGATGTCCATgttgatcatgatgatgaggatgatgatgaagacgaTGTTCCGCTCAATCAGCGCTCTTCCAAGGCCAATTCTTTAGCTTTTGCCAACTTGAAGAATCATAAATGTAATCAGTGCAATAAAGCATTTAGATACATCACAAATCTCTACAGACATAAACAAACTGATCACAATTCCATAGGgcagattaaaaaaaatgtcaaaaagcTATTAAGAAATCGTCAGGATGTGGATGAGAAGGATGATGACAACTACTACAAGTGCGACCAGTGTGACAAATCTTTTAAGTATGTCATGCTACTAGTCAAGCACAAACAAAAGTTTCATGGAGTCAATCAAATGCCATCGAGCCGAGGAGGAGCAGTAACAACTACAGCTACTCAGCCGAGACCCAAATTGAACACAGATTCTTTGGTTCATAGCCTTATCAAGGCAGTGGAAATTTCTGATGAGGACGGAAACTCCAGCTCGGATAACTACTATAAATGTGATCAGTGTGATAGGTCCTATAAATACATTGTTAGTCTAATCAAGCACAAGCACAAGGATCATTCGGAGAATTCTAAAAATTCCGCTGATGACGAAGATCAAGACCAAGCATCCACATCCAACTCTGCTAGCATCAGCGGTGCCCCAAAGCCTTCACGCATCAATCGTCGGGTTCAAGATTTTGACTTACACCGTTGTCAACCGAATGGCTCCAAGGAGATAAAATGCATGATCTGTCTACGTCGATTTGTCAAACTGGGCGAACTACGCGAGCATCTTAAATGCCATCCagttgattttgattttgaggCACATGGCGAGCCAATTGAACGCATAGCCGAGGGCTTCTTCAAAACGGCTGTCGAATCCACAAAAGAGGGTTTAAAACGACGCATTCTTAAGGATCTGCAAATAGGCTTGTATGGCCGTTACTACTCTATTACAAACGAGGCCCGCTATGAGATGAGTCTAGATAGCTCCGACACGGATAGCGACGGCGGTGATGCCGATGCCCAAGTAATCATACGGCGTAGCTATGCATGTGAATTGTGCGACTCTCCGAAACAGCCGGCCAAGTGGCCACGGAAATATCAATTACACGAGCATCACAGGCAGCATCACTCCTGGTTAGAGGCGCCCTATGTTTGCCATCGTTGTGATTCACGCTTCCTAAATGAGCAACTTCTAGAGCATCACACAAGCCAGCTGTGTAACAATACGTTGAAACGTTTTCAGTGCGACAAATGTCCGCAGCGTTTCTTTTGGCGCAAAAACTTGCGCTCACATTTGGTAGATCATAAAGATAAGCAAGAGAATTATCCGTGCGATCAGTGCCAGCGTAGTTTTCAGGATAAAAGTTCCGTAACTAGGCACAAATTAATGGTGCATGCAGATGGAAAGAGTCAGTTAATACCCTGCCGTTGGTGCACTAGAGTTTTCTATCGGCCGGCACTTCTGCATAAGCATCTTCAGCGCCATGGATTTAGCGGCAAAGACTTACCCTTGGCTGAGACATTGCTGGCCGATGCAGCCAAGCCTTTGGGCCCAAAGAATATACAATGTAAACTGTGTGATCTTCGATTTGTTAGTATTGCGGATTTGCGACGTCACATGGTCATGCTGGAACATGCTGCTCAGGCTACTAGCTATATGATCAGCACTGAAGCTGGATTTGAACTGCAACTGGATGATACAGACGATagcgacgatgatgatgggcaTACAAAGAGATCCTACACTTGCGACCTCTGCAAGATGAAACTTCCACGCAGGCGTGAGATGAGTGAGCATCAGTACTCGCTGCATACGTTTGATAAACTGCCATACGGATGCGATCAGtgcatatataaaactgtGGATAAGATCATGCTTAAACATCATCAAACGACCCAATGCCAAAACAAGgagaagaaatttatttgctcCCATTGTGGTTACAGGTTTATGTGGCAAGAAAATCTGGACCAGCACTTGTCTAGTCAGCATCCCAAACACAAAATTAACATGAACAGTCAAGAACAACAGTCACAGAGTTCTTCCATTCGCCGAAAAAGACGCTTTAGATACCAATGCCCCCATTGTTGGCGCTCTTTTGTCGTTCAACCCAGTTTGGATAAGCACATCAGGGACATGCATGTGGCTAAAAAAAATCCTGGAAAGAAGTATCTCTGCTCACTATGCGGTCTGGAATCGCTTACGCCCAACAAACTCAGCATTCATATCCGACGTCATATGGGGGAAAAACCCTTTAAATGCGATCTCTGCGATATGCGTTTCACTGTTCATTACGAACTAAAAGTGCATCGACGAAAACACACGGGCGAACGACCATATCAGTGCACGTTCTGTGACAAACATTTTGCCCGGCCCGATAAACTGAGACGTCATGTCTATATGCACAGCGATAAGCGctag
Protein Sequence: MPRTCRICAGDGGRFWIETPVEKYAGKTFNQLLLDLTKIELTMDQMEKLTPWICRNCAHKLQRSYDFVLKAKRTHEILVDRLMESMAVAKSHVVLEEEDPFCLRETPIQLMEIEGVTIKMEDSEPSTIITGDNTGPPYTVPDPLVREGVEKRAISDLSEAEDNDVHVDHDDEDDDEDDVPLNQRSSKANSLAFANLKNHKCNQCNKAFRYITNLYRHKQTDHNSIGQIKKNVKKLLRNRQDVDEKDDDNYYKCDQCDKSFKYVMLLVKHKQKFHGVNQMPSSRGGAVTTTATQPRPKLNTDSLVHSLIKAVEISDEDGNSSSDNYYKCDQCDRSYKYIVSLIKHKHKDHSENSKNSADDEDQDQASTSNSASISGAPKPSRINRRVQDFDLHRCQPNGSKEIKCMICLRRFVKLGELREHLKCHPVDFDFEAHGEPIERIAEGFFKTAVESTKEGLKRRILKDLQIGLYGRYYSITNEARYEMSLDSSDTDSDGGDADAQVIIRRSYACELCDSPKQPAKWPRKYQLHEHHRQHHSWLEAPYVCHRCDSRFLNEQLLEHHTSQLCNNTLKRFQCDKCPQRFFWRKNLRSHLVDHKDKQENYPCDQCQRSFQDKSSVTRHKLMVHADGKSQLIPCRWCTRVFYRPALLHKHLQRHGFSGKDLPLAETLLADAAKPLGPKNIQCKLCDLRFVSIADLRRHMVMLEHAAQATSYMISTEAGFELQLDDTDDSDDDDGHTKRSYTCDLCKMKLPRRREMSEHQYSLHTFDKLPYGCDQCIYKTVDKIMLKHHQTTQCQNKEKKFICSHCGYRFMWQENLDQHLSSQHPKHKINMNSQEQQSQSSSIRRKRRFRYQCPHCWRSFVVQPSLDKHIRDMHVAKKNPGKKYLCSLCGLESLTPNKLSIHIRRHMGEKPFKCDLCDMRFTVHYELKVHRRKHTGERPYQCTFCDKHFARPDKLRRHVYMHSDKR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00600495;
90% Identity: iTF_00556012; iTF_00483888; iTF_00591138; iTF_00577958;
80% Identity: -