Basic Information

Insect: Drosophila neocordata
Gene Symbol: -
Assembly: GCA_018903615.1
Location: JAEIGI010000002.1:394657-397795[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 3.8e-05 0.0031 18.0 7.4 1 23 198 221 198 221 0.97

2 16 0.00019 0.016 15.7 4.7 1 23 250 273 250 273 0.97

3 16 0.002 0.17 12.5 3.3 1 23 325 348 325 348 0.96

4 16 0.061 5 7.9 1.9 2 21 402 421 401 423 0.94

5 16 0.82 67 4.3 1.5 1 20 541 560 541 562 0.81

6 16 0.014 1.2 9.9 1.3 1 23 571 593 571 593 0.94

7 16 9.9e-05 0.0081 16.7 1.1 1 23 600 623 600 623 0.96

8 16 0.00021 0.017 15.7 0.9 2 23 632 653 631 653 0.96

9 16 0.00044 0.036 14.6 0.1 2 21 680 699 679 703 0.90

10 16 0.033 2.7 8.7 0.7 1 23 739 762 739 762 0.96

11 16 4.3 3.5e+02 2.1 0.3 3 22 771 790 770 790 0.92

12 16 0.011 0.91 10.2 0.9 1 23 799 822 799 822 0.94

13 16 1.5e-05 0.0012 19.3 0.5 1 23 849 872 849 872 0.97

14 16 0.21 17 6.2 0.2 1 23 882 904 882 904 0.93

15 16 5.8e-05 0.0048 17.4 3.7 1 23 910 932 910 932 0.99

16 16 6e-06 0.00049 20.5 3.2 1 23 938 960 938 960 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	3.8e-05	0.0031	18.0	7.4	1	23	198	221	198	221	0.97
2	16	0.00019	0.016	15.7	4.7	1	23	250	273	250	273	0.97
3	16	0.002	0.17	12.5	3.3	1	23	325	348	325	348	0.96
4	16	0.061	5	7.9	1.9	2	21	402	421	401	423	0.94
5	16	0.82	67	4.3	1.5	1	20	541	560	541	562	0.81
6	16	0.014	1.2	9.9	1.3	1	23	571	593	571	593	0.94
7	16	9.9e-05	0.0081	16.7	1.1	1	23	600	623	600	623	0.96
8	16	0.00021	0.017	15.7	0.9	2	23	632	653	631	653	0.96
9	16	0.00044	0.036	14.6	0.1	2	21	680	699	679	703	0.90
10	16	0.033	2.7	8.7	0.7	1	23	739	762	739	762	0.96
11	16	4.3	3.5e+02	2.1	0.3	3	22	771	790	770	790	0.92
12	16	0.011	0.91	10.2	0.9	1	23	799	822	799	822	0.94
13	16	1.5e-05	0.0012	19.3	0.5	1	23	849	872	849	872	0.97
14	16	0.21	17	6.2	0.2	1	23	882	904	882	904	0.93
15	16	5.8e-05	0.0048	17.4	3.7	1	23	910	932	910	932	0.99
16	16	6e-06	0.00049	20.5	3.2	1	23	938	960	938	960	0.98

Sequence Information

Coding Sequence: ATGCCAAGAACCTGCCGAATTTGCGCTGGAGATGGGGGTCGATTTTGGATCGAGACTCCTATAGAGAAGTATGCTGGGAAAACATTCAATCAGTTGCTTCTAGATCTGACCAAAATTGAAGTGACCATGGACCAAACAGAGAAGTTAACGCCGTGGATATGCCGCAATTGTGCCCATAAACTGCAACATGCTTATGACTTTGTTTTAAAGGCCAAAAGGACGCATGAGGTTTTGATAGCTAGAATGCTAGAGTCAATGGATATGGCCAATAAAAATGCGATACTAGAAGATGAAGGCCCATTCTGCCTACGTGAGACTCCTATACAGTTAATGGAGATTGAGGGAGTGACTATTAAAATGGAAGATTCCTCCGAACCAACTGCTCTTAATGATGGTGACTTAACGTCGCCTGCTATGCCTGATCCTTTGGTCCGTGCGGGCATTGCGAAGCGTGCCATTTCAGAGACAAGCGAAGTCGAAGATGACGATAATCATGTTGATCTTAATAATGACGATGATGATCAAGACGATGTTCCTCTGAATCAGCGCTCTTCCAGGTCCAATTCACTAATTTTTACCCAATTGAAGAAGCATAAATGTAACCACTGCAATAAAGCATTTAGGTACAGTACAAATCTTTATAGGCACAAACAAACAGAGCACAATTCCATAGAGCAGATTAAAAAAAATGTAAAGAAACTATTAAGAAATCGGCAGGATGTGGATGAGAAGGATGATGACAACTACTATAAGTGCGATCATTGTGATAAATCCTTCAAGTATGTCATGCTATTGGTCAAGCACAAACAAAAATTTCATGGAGTCAATCAAATGCCATCTAGCCGAGAAGTAGCAGCTGCTAATGCAGCGCCTCAGCCGAGACCCAAACTAAACACAGATTCTTTGGTTCATAGCCTTATCAAAGCAGTGGAAATTTCTGATGAGGATGGCAACTCCAGCTCAGATAATTACTATAAATGCGATCAATGTGAGAAGTCCTATAAATACATTGTTAGTCTAATCAAGCACAAGCATAAGGATCATTCTGAGAACTCCAAAAATTGCGCAGATGATGAAGAACAAGACCAACCATCCACATCCAACTCTGGTACAATCTCTGTTGCCACAAAACCCTCTCGCATTAATCGTCGGGTTCAGGACTTTGACTTACATCGGTGCCAGCCGAATGGTTCCAAGGAGATAAAATGCATGATCTGTTTACGACGTTTTGTCAAACTGGGCGAGCTACGGCAGCATCTTAAATGCCATCCAGTTGATTTTGATTTTGAGGCACATGGCGAGCCAATTGAACGCATAGCCGAGGGTTTTTTTAAAACGGCTGTTGAATCCACAAAAGAGGGTTTAAAGCGCCGAATTCTAAAGGATCTAGAAATTGGGTTGTATGGCCGTTACTACTCCATTACAAATGAGGCCCGCTATGAGATGAGCCTAGATAGCTCCGATACGGATAGTGACGGCGGCGATGCCGATGCCCAAGTGATTATACGGCGGAGCTATGCATGTGAATTGTGCGACTCCCCAAAACAACCGGCCAAATGGCCTCGGAAATATCAATTGCACGAGCATCACAGGCAACATCACACTTGGTTAGAGGCTCCCTATGTCTGCCATCGTTGCGATTCCCGGTTCCTGAACGAGCAACTTCTGGAGCATCATACTAGTCAGCTTTGTAATAATACGTTGAAAAGATTTCAGTGCGACAAATGTCCACAGCGTTTCTTTTGGCGAAAAAACTTACGATCACATTTGGTGGATCATAAGGATAAACAAGATAATTATCCGTGCGATCAATGCCAGCGAAGTTTTCAGGATAAAAGTTCTGTAACCAGGCATAAATTAATGATGCATGCAGACGGGAAGAGTCAGTTGATACCATGCCGTTGGTGCACAAGGGTTTTCTATCGGCCAGCACTGCTGCATAAGCATCTCCAGCGCCATGGATTTAGTGGTCAAGATTTACCATTGGCTGAGACATTGCTGGCCGATGCAGCCAAGCCTTTGGGTTCAAAGAATATTCAATGCAAACTGTGTGATCTTCGATTCGTTAGCATTGCGGATTTGCGACGTCATATGGTCATACAGGAGCACGCTGCTCATGCTAGTAACTATATGATCAGCACTGAAGCTGGATTTGAACTACAACTAGATGATACAGATGATAGCGATGATGACGACGGTCATACAAGGAGATCGTACACTTGTGATATCTGCAAGATGAAACTTCCACGCAGGCGTGAGATGAGTGAGCATCAGTACTCATTACATACGTTCGATAAACTGCCGCACGGATGCGATCAGTGCATATATAAAACTGTAGATAAGATCATGCTTAAACATCATCAAATGACCCAATGCCAAAACAAGGAGAAGAAATTTATTTGTTCCCATTGTGGTTACAAGTTTATGTGGCAAGAAAATCTAGACCAGCATTTGGCCAGTCAGCATCCCAAAAACAAAATTAACATTAGCAGCCAAGAGCAACAGTCACAAAGTTCTTCCATTCGTCGAAAAAGACGGTTTAGATACCAATGCCCCCATTGTTGGCGTTCCTTTGTTGTTCAACCCAGTTTGGATAAGCACATCAGGGACATGCATGTGGCTAAAAAGAATCCTGGAAAAAAGTATCTCTGTTCCCTATGTGGACTAGAGTCCCTTACGCCCAACAAACTCAGCATTCATATTCGACGTCATATGGGAGAAAAACCCTTCAAATGCGATCTCTGCGATATGCGCTTCACTGTTCATTACGAACTTAAAGTGCATCGACGAAAACATACGGGCGAACGACCATATCAGTGCACGTTTTGCGACAAACATTTTGCCCGGCCCGATAAACTAAGACGACATGTCTATATGCACAGCGATAAGCGTTAA
Protein Sequence: MPRTCRICAGDGGRFWIETPIEKYAGKTFNQLLLDLTKIEVTMDQTEKLTPWICRNCAHKLQHAYDFVLKAKRTHEVLIARMLESMDMANKNAILEDEGPFCLRETPIQLMEIEGVTIKMEDSSEPTALNDGDLTSPAMPDPLVRAGIAKRAISETSEVEDDDNHVDLNNDDDDQDDVPLNQRSSRSNSLIFTQLKKHKCNHCNKAFRYSTNLYRHKQTEHNSIEQIKKNVKKLLRNRQDVDEKDDDNYYKCDHCDKSFKYVMLLVKHKQKFHGVNQMPSSREVAAANAAPQPRPKLNTDSLVHSLIKAVEISDEDGNSSSDNYYKCDQCEKSYKYIVSLIKHKHKDHSENSKNCADDEEQDQPSTSNSGTISVATKPSRINRRVQDFDLHRCQPNGSKEIKCMICLRRFVKLGELRQHLKCHPVDFDFEAHGEPIERIAEGFFKTAVESTKEGLKRRILKDLEIGLYGRYYSITNEARYEMSLDSSDTDSDGGDADAQVIIRRSYACELCDSPKQPAKWPRKYQLHEHHRQHHTWLEAPYVCHRCDSRFLNEQLLEHHTSQLCNNTLKRFQCDKCPQRFFWRKNLRSHLVDHKDKQDNYPCDQCQRSFQDKSSVTRHKLMMHADGKSQLIPCRWCTRVFYRPALLHKHLQRHGFSGQDLPLAETLLADAAKPLGSKNIQCKLCDLRFVSIADLRRHMVIQEHAAHASNYMISTEAGFELQLDDTDDSDDDDGHTRRSYTCDICKMKLPRRREMSEHQYSLHTFDKLPHGCDQCIYKTVDKIMLKHHQMTQCQNKEKKFICSHCGYKFMWQENLDQHLASQHPKNKINISSQEQQSQSSSIRRKRRFRYQCPHCWRSFVVQPSLDKHIRDMHVAKKNPGKKYLCSLCGLESLTPNKLSIHIRRHMGEKPFKCDLCDMRFTVHYELKVHRRKHTGERPYQCTFCDKHFARPDKLRRHVYMHSDKR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00600495;
90% Identity: iTF_00501246;
80% Identity: -