Basic Information

Insect: Drosophila bipectinata
Gene Symbol: hang
Assembly: GCA_018153845.1
Location: JAECYF010000108.1:10919785-10929593[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 19 0.26 20 5.8 1.0 3 23 418 439 417 439 0.93

2 19 0.33 25 5.5 3.2 3 22 547 566 545 566 0.89

3 19 0.00056 0.042 14.2 3.3 1 22 669 690 669 692 0.90

4 19 0.043 3.2 8.2 0.1 2 21 704 723 703 724 0.93

5 19 0.00065 0.049 14.0 0.2 2 23 851 873 850 873 0.95

6 19 0.0019 0.14 12.5 0.1 1 23 881 904 881 904 0.96

7 19 1.5e-05 0.0011 19.1 0.1 2 23 995 1016 994 1016 0.97

8 19 0.00027 0.02 15.2 2.9 2 23 1099 1121 1098 1121 0.97

9 19 0.021 1.6 9.2 0.2 2 23 1130 1152 1129 1152 0.95

10 19 0.00074 0.056 13.8 0.2 1 23 1165 1188 1165 1188 0.97

11 19 0.00012 0.0088 16.3 1.1 1 23 1243 1265 1243 1265 0.99

12 19 0.0018 0.14 12.6 0.9 1 23 1273 1296 1273 1296 0.96

13 19 0.71 53 4.4 0.3 2 19 1304 1321 1304 1322 0.93

14 19 2.5e-05 0.0018 18.4 0.4 3 23 1427 1447 1426 1447 0.98

15 19 0.0047 0.35 11.3 0.1 1 23 1484 1506 1484 1506 0.97

16 19 5.8e-05 0.0043 17.3 0.6 2 23 1601 1623 1600 1623 0.93

17 19 1.3 96 3.6 0.1 2 20 1643 1661 1642 1663 0.91

18 19 0.0061 0.46 10.9 0.4 3 23 1678 1698 1678 1698 0.98

19 19 9.5e-05 0.0071 16.6 2.1 1 23 1995 2017 1995 2017 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	19	0.26	20	5.8	1.0	3	23	418	439	417	439	0.93
2	19	0.33	25	5.5	3.2	3	22	547	566	545	566	0.89
3	19	0.00056	0.042	14.2	3.3	1	22	669	690	669	692	0.90
4	19	0.043	3.2	8.2	0.1	2	21	704	723	703	724	0.93
5	19	0.00065	0.049	14.0	0.2	2	23	851	873	850	873	0.95
6	19	0.0019	0.14	12.5	0.1	1	23	881	904	881	904	0.96
7	19	1.5e-05	0.0011	19.1	0.1	2	23	995	1016	994	1016	0.97
8	19	0.00027	0.02	15.2	2.9	2	23	1099	1121	1098	1121	0.97
9	19	0.021	1.6	9.2	0.2	2	23	1130	1152	1129	1152	0.95
10	19	0.00074	0.056	13.8	0.2	1	23	1165	1188	1165	1188	0.97
11	19	0.00012	0.0088	16.3	1.1	1	23	1243	1265	1243	1265	0.99
12	19	0.0018	0.14	12.6	0.9	1	23	1273	1296	1273	1296	0.96
13	19	0.71	53	4.4	0.3	2	19	1304	1321	1304	1322	0.93
14	19	2.5e-05	0.0018	18.4	0.4	3	23	1427	1447	1426	1447	0.98
15	19	0.0047	0.35	11.3	0.1	1	23	1484	1506	1484	1506	0.97
16	19	5.8e-05	0.0043	17.3	0.6	2	23	1601	1623	1600	1623	0.93
17	19	1.3	96	3.6	0.1	2	20	1643	1661	1642	1663	0.91
18	19	0.0061	0.46	10.9	0.4	3	23	1678	1698	1678	1698	0.98
19	19	9.5e-05	0.0071	16.6	2.1	1	23	1995	2017	1995	2017	0.98

Sequence Information

Coding Sequence: ATGGCAAAACTGACCACATTAAAGTCCAATATTAAGCGGGGATGGATGGATGGATGGATGGCTCCACCTCATCCCCTGGCCATTGGCCGCCCATCCTACTGCTCCATCTACTCCTGTTGTATCTGGTGGAAGAGAAGAGGTGTGGGCAAGATCACGCCCCAGGATCGATTGTCCTTGCAGATATGCCACGCCTGCATCAGCTACCTCAACTCGTGGCAGAGCTTCAAGAACCGATCCCTCATCTCCCAGACCAAGCAGCGCCAGTGGCTGGAGGCGAACAACAGCAGTAGCATCCACAAGAGCAAGCTGCTCAACTACCTGGACCTGAACAGTGCCGAGAATGGCTCTGCCTCCGATCATCATCATCATCAGCAGCGACAGAACCAGAACCAGAACCAGCAGCACGTCCTGGAGAATGAGGATGAAACGGACAATGCCGGGATACAGGGAGCGGCAGCCACAGCGGCTGCCATTCTGGACGGCATACCCTCGTTGAAGAAACGAAAATCTCTAACAGTCTATGGAAGGCACAATCCCACGGCGAACTCCTCCTCGTCCTCCTCCGCCACCGCCTCAGGTGGCTCATCCACGCTGCGGAAATTCAAGCCGAAACTGTACTTGCCGCTGGATATAGCGGTGCCACCACTGCCGCCGCTGCCCGTGACTGCTCCCGCTGCCGTTGCTCCTCCGTCTGCCCTTGCCCTTCCACCCCCTCCTGCTCCGCCGCCGCCGCTTCCGGCCGCCGGCGCCCCCAATCCTCCGCCTGCTGGCGTGGCTGGTGGCAGGGAGAGCTTGTCGGTGGCACTGCCACTGGATTTCAGCCAAGCTAGCTGCAGCAGCAGCAGCAGCAACAATCGCCTGTCCGGCCTCCTCCTCCAGCAGCAGCAACAGTCGGCTGCCGCAACTGGCGCTGCGCCACCTTCCGCTACCGCTACCGCATCCGCATCCGCGTCCACGTCCACGTCCGCATCTGCTCCATTGCTCATGCCGCCACTGCCAGCGGTGCCCATCAAAGATGAGCCCATCGACACGGACGACGACTACCAGATGAAGTCGATTGACGAGTCCGACGACATGGTCGATCCCACAATGTTCCTAGAGCGCTCCGAGCACGAGGGCGACATGCCGTTGATGACCTCCGACTACGACTACACGGCCCAACATGGCGTCACCGCCGCCTCGGCAGCCGCCTCCCTGCCGGCCAATGCCGTCGCCAATGTGGCCGCTGCCGGCGACTCCAAGGTGGCCAGCTGCCGGGCCTGCAGCCTGCAGTTCTCTACGCGCGCCAATGCCCGTCGCCACGAACGCAACCTGCACCCCAATCTGTTCCAGCTCTCCACCGACTCGCCCCACAACACGCCCATCACCAAGCCCACGCCCGCCCTGGCCGCCGCCCTGGAGATCCAGCGGGCAGCCGCCGAGGCAGCCACCGCTGAGGCGAATCGAGCTGCCGGAGCGGCGGGCGGGAACATCTCCACCCAGAAGTACAGGCAGGTGGTGATGAATGCGTTCATCAAGTGCGAGGGCGGCGGCTACGACTATGAGAATCCGGAGCAGTACCGGGCGCACCTCACCCGCGACAAGGTGGAGTTCATCGAGCAGAACGAGGAGTTCCTCGAGCAGTACCAGACGATGACGTGCCGGTGCTGCAACAAGTACTTCAGCACCTACAAGAACTTCATGGCCCACGTCCGCAAGAAGTATCCGCTGCTGCCGCGCAACCTGTGCTTCAACTGCCTCAAGATGAACGACTCCAAGGCCCTGTTCATCTCCCACCTGAAGAAGAGGAACTGCATCAACCTGTACCGGGTGCTGCACGGCATTCGGGAGAAGGCCAACGCCTCTATCTCCAAGGACGCCACTCTGATCGAGGGGGGCGATGGGCGAGTTGGCCACCTGGATGCCGGCTCCAGTCCCAATGTGACCGGCGACGTAATCTCCAGTGCGGCCGGATCGGAGCGACCGGAGAAGCTGCGGGCCAAGGAGCTGCTGGTGAACAAGCTGTACGAGTGCAAGCTGTGCCCCAAGGGCTTCCGGACCAAGCACGAGTTCCGGACGCACGTCTACGACAAGCACGCGGACGTCCAGCGCAAGGACAGCAACTCGATCCAGTGCAACTTCTGCGGCCTGGACTTTGCCGACCCGGTGGACCGGCGGCGCCACTACAACAACATGGACTGCATCGTGCGCCTGCGCTGCATGACCTGTGACGCCAAGCTGGAGACGCACCAGCGCTTCCTCGAGCACGTCTACCAGGACCACCTGGGCGGCGTGGGCGGCGGCAGTGGCACCGGCGGCGGAGGCGCCAGCAGCGACAATGCCTCCACCACGGGCAACAGCATGGAGCACTCGCCGGGCAAGCGCAGCCTGCTCAGTGCCCTGGGCATCGGAGTGGGCTCCTCGGCGGACGAATCGCGCAGCAGCAGTGTGGCCCTCGGGCCGATGACCTCCACGCCCAAGCCGGGCAATCAACAGAATCCTTCTGCAGCTGGTACCGGCGGCGGCAATGGCTCTGCCCCGAAGTCGCAGTACTTCTCCCGCATGCCCCAGGTCTGCCCCATTTGCGGCCAGCAGTACAACAACTACAACAACGTGCTCCGGCACATGGAATCGAAGCATCCGAACAAGCTGCCGGAGACGTACAAGTGCGTGCGGTGCGGCCTGGGCTATCCGAGGATCTCGTACCTGCGGGAGCACATGATCAACGTGCACGGCGTGGACAAGAACCGGCACTCGGGCGGCTTCGAGTACATCGTGAACGCGGACGCCGTGAAGCTGGCGGACGGGAGCACCCCCAACGTGTACACCGGTCGCTACGACTACGTGATGAAGGACCTCATGTCGATAACAAATGGTGGGACCCTCGATGACGACGACGAGGAGCCGGGCAGCGTGGCCAAGAAGATGCGCCTGGACGACAGCAGCAACAACAGCAGCCTGGCCGGCGTGGGCGTCTCCAGCCAGCAGCAGCAACAGCAGAAGGAGTGCCCCATCTGCAACGCCGTCTTCAGCAACAACATCGGCCTCTCCAACCACATGCGCTCCCACTACACGGCCTCCAACTCGGTGAACGCCGCCCTAACGGCGGCTAATAGGATGACGCCCAAATCCCTGACCATAACGGCCGCCCCGGCCGACACCAGCATGGACCTGCTAACTGGAGGCTCTTCCACGCCCGCGGCATCATCATCAGCGGCGGGTGTGCCGCCCGCCATGGCCAACCAGACGCCGCAGGAGCAGGCCGTGTTCCGGCGCAGCCTCGACCAGGCGGCCGACCGGCGGTTCCGGCGCATGCGCTGCCGCATCTGCCAGCGACGGTTCAGCTCGAAGAAGTCCTACCGCTACCACATGCTCACCGACCACCAGGTGCAGAACGTGCAGTTCATCAAGTGCAAGCTCTGCAACGCGGAGTTCGCCTACGAGAAGGGCCTCAAGGTGCATCTGTTCAAGGTGCACGGGCGGGCCATCAAGGACGAGATGATCGTGAAGCAGTTCGAGTGCGAGGTCTGCTCGATTGTGTACAGCTCCGAGATGGAGCTGCAGCAGCACAAGCGCAGTGTCCACAAGATGTCCTCCGCATCGGCAGCAGCGACCGCCGCCTCCTCCTCCTCCTCGAAAATGGACGACGACAGCAGCATTGTCGTGGATGACAGCACCCTGAAGCCGGCGGGCGGTGACCTGACAGACACCTCCGCCAGCGTCAGCCTGAGCACGCCGCTGTACTGGTACCAGTGCAAGTACTGCCCCTCCAACTTCAACACCAACAAGAAGCTGGCCATCCACATCAACTCGCACGACGAGTTCGACTCCAACGACTACTCCTGCAAGGACTGCGGCAATGTCTACAGTGGAAGGAAGAGTCTATGGGTCCATCGATATAAGAAGCATCCACAGGTCCCAGACCCGGCCGAGTGCTCGCTCTGCCGCAAGATCTTCTTCGACCGCCAGATGCTGGACAATCACACGCCGACGTGCAACCGCAAGCCCATCACCTCAACCGGCGCCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTATTGCCCTCCAGAAGCAGGTGGGCCTGCACTCTGGCATCTTCCGGCACAAGACCGGCGACGATGACGACGACGATGACGAGGATGAGCAGCACCAGAAGCTGGCCGATGGAGCTGGCGACAGTGGAGCAGTTGCATCAACGCCAGCTCCGGCCCCGGCCACCACAACAGCAACCTCGGTTAAGATACGCATTCCAGAGGTGGCGTGCACCATTTGCGGGGCCCGCTTCACCGACCAGGAGATGTTCACCAAGCACATCCAGAAGCACGAACAGGAACTGTACGTGGACAATCCCCTGGCGGCGATGTTCGACGATGGGCCGCCCGACGCCGGCCAGTTTCAGGTGGAGCTCGAGAAGCAGAACGAGAACGGGGAGTACGCGTGCGATCTGTGCGCGAAGACGTTCCCCCAGGTCATAGCACTCAAGGTGCACCGCAAGTGGCATTTCAGAGGTGATAGCAAGCAGAATCCCATCGACGGCGAAGCGACACATTTGACCAACAACAACCANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCTGGGGAGCAAGTCGATGAAGCGGAAGCGTGAACTAAAGTGCGAATACTGCCCCTCGACGTTCATCAGCAACAACAACCTGCGCCGGCACATGTACGAGCTGCACAAGCACGAGGTGAGCAACCTGCCGGAGCCGCCGGTCATCGTGGTGGACGACCATCTCTCCTGCCGCCGGTGCAACCTCAAGTTCGAGACGAAGGAGCTGTGGATCGACCACAAGCTGGCGGACGCCAAGGTGGTGCGACCGTTCTGCCCCTTCCAGTGGGGCTGTGATCTGTGCGGCGAGTACCTGTCGCGCAAGGAGAAGCTGATGAATCACATCAACAACCATCTCAAGGAGGAGGTCATTGTGCCGGTGGCCACCAAGGAGGCGGCGGAGAGGGCGGCAGCAAAGCCGCAGGAGGCAGGGGCAGTTGCGGTATCGAATGCCACCGCTAAGCTGGAGGAGCCCGATCAGAAGGCGGACGACGTCGGCAAGTCGGAGGGTAAGCCTCTGCCGGACAGCGATGATCTGGACGAGGAGGACAGCTCCGGTGAGGAGGAGACCTCTGGCACGGGCGATGACGAGGATGACGACGATGATGAGGAGGACTCGGAGGAGGATGTGGAGGACGAGGAGGACGACGAGGGCGATGGCGGCGAGGGCGAGGACGAGGAAGGTGTCCCCCCGCAGCAGCAGCCGCCCAAGATGAACCTCGCCCAGGACGATGATCTGGTCGAGGAGGTGCTCAGCTCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTGGAAGAGCCCCAGCCGGTGGTGATGAACGGCAAGTCGAAAATGCCGCCACTCATTGTGGCCACCTCGGACGAGGAGGATGAGGAGGACGGCATGCTGCCCATCGAAGACATAATCGAGGAGGAATTCGACGAGGACGCCGCCGATCCGGAGCCCGAGGACGACATTGTCGAGGAGGACGAGGTTGAGGAGGTGGAGGAGGAGGTAGATGAGGTGGAAGAGGAAGAGGTAATCGAAGAACTGGACGATGACATGGACGAGGTGGGCAACGAAAGGCGCAACTCGTCGTCGGCCAGCGAGTCGAACACAACCGCCACCACCACGACCACGTCGCAGTCACATTCCACGGGTGAGCGGCACAAAAAGGTGCCGGAGGTGCCAGGCTTTACCTGTGATCTATGTCAACTTTGTTTCGATTCTCAGGAGCTTCTCCAGAGCCACATCAAAAGCCATTTCCTCAATGGTCCAAAGCTGGCCAAGGTCAAGGTGGTAGCCGGAGGAGGAGCAGCGGCAGCGGCAGCATCATCCTTAACAACGGAAGCGGTGCCCTCAAAGACGACATCGACAACGACGAGTACCAGTAAGAGTAGTAAGCCACCAGCGGCTGCCACCAATGCTGCCACAGTCATCCTCCATCTCACTTGA
Protein Sequence: MAKLTTLKSNIKRGWMDGWMAPPHPLAIGRPSYCSIYSCCIWWKRRGVGKITPQDRLSLQICHACISYLNSWQSFKNRSLISQTKQRQWLEANNSSSIHKSKLLNYLDLNSAENGSASDHHHHQQRQNQNQNQQHVLENEDETDNAGIQGAAATAAAILDGIPSLKKRKSLTVYGRHNPTANSSSSSSATASGGSSTLRKFKPKLYLPLDIAVPPLPPLPVTAPAAVAPPSALALPPPPAPPPPLPAAGAPNPPPAGVAGGRESLSVALPLDFSQASCSSSSSNNRLSGLLLQQQQQSAAATGAAPPSATATASASASTSTSASAPLLMPPLPAVPIKDEPIDTDDDYQMKSIDESDDMVDPTMFLERSEHEGDMPLMTSDYDYTAQHGVTAASAAASLPANAVANVAAAGDSKVASCRACSLQFSTRANARRHERNLHPNLFQLSTDSPHNTPITKPTPALAAALEIQRAAAEAATAEANRAAGAAGGNISTQKYRQVVMNAFIKCEGGGYDYENPEQYRAHLTRDKVEFIEQNEEFLEQYQTMTCRCCNKYFSTYKNFMAHVRKKYPLLPRNLCFNCLKMNDSKALFISHLKKRNCINLYRVLHGIREKANASISKDATLIEGGDGRVGHLDAGSSPNVTGDVISSAAGSERPEKLRAKELLVNKLYECKLCPKGFRTKHEFRTHVYDKHADVQRKDSNSIQCNFCGLDFADPVDRRRHYNNMDCIVRLRCMTCDAKLETHQRFLEHVYQDHLGGVGGGSGTGGGGASSDNASTTGNSMEHSPGKRSLLSALGIGVGSSADESRSSSVALGPMTSTPKPGNQQNPSAAGTGGGNGSAPKSQYFSRMPQVCPICGQQYNNYNNVLRHMESKHPNKLPETYKCVRCGLGYPRISYLREHMINVHGVDKNRHSGGFEYIVNADAVKLADGSTPNVYTGRYDYVMKDLMSITNGGTLDDDDEEPGSVAKKMRLDDSSNNSSLAGVGVSSQQQQQQKECPICNAVFSNNIGLSNHMRSHYTASNSVNAALTAANRMTPKSLTITAAPADTSMDLLTGGSSTPAASSSAAGVPPAMANQTPQEQAVFRRSLDQAADRRFRRMRCRICQRRFSSKKSYRYHMLTDHQVQNVQFIKCKLCNAEFAYEKGLKVHLFKVHGRAIKDEMIVKQFECEVCSIVYSSEMELQQHKRSVHKMSSASAAATAASSSSSKMDDDSSIVVDDSTLKPAGGDLTDTSASVSLSTPLYWYQCKYCPSNFNTNKKLAIHINSHDEFDSNDYSCKDCGNVYSGRKSLWVHRYKKHPQVPDPAECSLCRKIFFDRQMLDNHTPTCNRKPITSTGAXXXXXXXXXXXXXXXXXXXXXXXIALQKQVGLHSGIFRHKTGDDDDDDDEDEQHQKLADGAGDSGAVASTPAPAPATTTATSVKIRIPEVACTICGARFTDQEMFTKHIQKHEQELYVDNPLAAMFDDGPPDAGQFQVELEKQNENGEYACDLCAKTFPQVIALKVHRKWHFRGDSKQNPIDGEATHLTNNNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLGSKSMKRKRELKCEYCPSTFISNNNLRRHMYELHKHEVSNLPEPPVIVVDDHLSCRRCNLKFETKELWIDHKLADAKVVRPFCPFQWGCDLCGEYLSRKEKLMNHINNHLKEEVIVPVATKEAAERAAAKPQEAGAVAVSNATAKLEEPDQKADDVGKSEGKPLPDSDDLDEEDSSGEEETSGTGDDEDDDDDEEDSEEDVEDEEDDEGDGGEGEDEEGVPPQQQPPKMNLAQDDDLVEEVLSSXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXEEPQPVVMNGKSKMPPLIVATSDEEDEEDGMLPIEDIIEEEFDEDAADPEPEDDIVEEDEVEEVEEEVDEVEEEEVIEELDDDMDEVGNERRNSSSASESNTTATTTTTSQSHSTGERHKKVPEVPGFTCDLCQLCFDSQELLQSHIKSHFLNGPKLAKVKVVAGGGAAAAAASSLTTEAVPSKTTSTTTSTSKSSKPPAAATNAATVILHLT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00539095; iTF_00566231; iTF_00580125;
90% Identity: iTF_00566231;
80% Identity: -