Basic Information

Insect: Drosophila malerkotliana
Gene Symbol: hang
Assembly: GCA_018153235.1
Location: JAECXV010000038.1:7405385-7413109[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 19 0.26 19 5.8 1.0 3 23 366 387 365 387 0.93

2 19 0.33 24 5.5 3.2 3 22 495 514 493 514 0.89

3 19 0.00055 0.041 14.2 3.3 1 22 617 638 617 640 0.90

4 19 0.043 3.1 8.3 0.1 2 21 652 671 651 672 0.93

5 19 0.00064 0.047 14.0 0.2 2 23 799 821 798 821 0.95

6 19 0.0018 0.14 12.6 0.1 1 23 829 852 829 852 0.96

7 19 1.5e-05 0.0011 19.1 0.1 2 23 943 964 942 964 0.97

8 19 0.00026 0.019 15.2 2.9 2 23 1046 1068 1045 1068 0.97

9 19 0.021 1.5 9.2 0.2 2 23 1077 1099 1076 1099 0.95

10 19 0.00073 0.054 13.8 0.2 1 23 1112 1135 1112 1135 0.97

11 19 0.00012 0.0085 16.3 1.1 1 23 1190 1212 1190 1212 0.99

12 19 0.0018 0.13 12.6 0.9 1 23 1220 1243 1220 1243 0.96

13 19 0.7 51 4.4 0.3 2 19 1251 1268 1251 1269 0.93

14 19 2.4e-05 0.0018 18.5 0.4 3 23 1382 1402 1381 1402 0.98

15 19 0.0047 0.34 11.3 0.1 1 23 1439 1461 1439 1461 0.97

16 19 5.7e-05 0.0042 17.3 0.6 2 23 1554 1576 1553 1576 0.93

17 19 1.3 93 3.6 0.1 2 20 1596 1614 1595 1616 0.91

18 19 0.0061 0.45 10.9 0.4 3 23 1631 1651 1631 1651 0.98

19 19 9.4e-05 0.0069 16.6 2.1 1 23 1946 1968 1946 1968 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	19	0.26	19	5.8	1.0	3	23	366	387	365	387	0.93
2	19	0.33	24	5.5	3.2	3	22	495	514	493	514	0.89
3	19	0.00055	0.041	14.2	3.3	1	22	617	638	617	640	0.90
4	19	0.043	3.1	8.3	0.1	2	21	652	671	651	672	0.93
5	19	0.00064	0.047	14.0	0.2	2	23	799	821	798	821	0.95
6	19	0.0018	0.14	12.6	0.1	1	23	829	852	829	852	0.96
7	19	1.5e-05	0.0011	19.1	0.1	2	23	943	964	942	964	0.97
8	19	0.00026	0.019	15.2	2.9	2	23	1046	1068	1045	1068	0.97
9	19	0.021	1.5	9.2	0.2	2	23	1077	1099	1076	1099	0.95
10	19	0.00073	0.054	13.8	0.2	1	23	1112	1135	1112	1135	0.97
11	19	0.00012	0.0085	16.3	1.1	1	23	1190	1212	1190	1212	0.99
12	19	0.0018	0.13	12.6	0.9	1	23	1220	1243	1220	1243	0.96
13	19	0.7	51	4.4	0.3	2	19	1251	1268	1251	1269	0.93
14	19	2.4e-05	0.0018	18.5	0.4	3	23	1382	1402	1381	1402	0.98
15	19	0.0047	0.34	11.3	0.1	1	23	1439	1461	1439	1461	0.97
16	19	5.7e-05	0.0042	17.3	0.6	2	23	1554	1576	1553	1576	0.93
17	19	1.3	93	3.6	0.1	2	20	1596	1614	1595	1616	0.91
18	19	0.0061	0.45	10.9	0.4	3	23	1631	1651	1631	1651	0.98
19	19	9.4e-05	0.0069	16.6	2.1	1	23	1946	1968	1946	1968	0.98

Sequence Information

Coding Sequence: ATGATGGTAATGATCACGCCCCAGGATCGATTGTCCTTGCAGATATGCCACGCCTGCATCAGCTACCTCAACTCGTGGCAGAGCTTCAAGAACCGATCCCTCATCTCCCAGACCAAGCAGCGCCAGTGGCTGGAGGCGAACAACAGCAGTAGCATCCACAAGAGCAAGCTGCTCAACTACCTGGACCTGAACAGTGCCGAGAATGGCTCTGCCTCCGATAATCATCATCATCAGCAGCAGCGACAGAACCAGAACCAGCAGCACGTCCTGGAGAATGAGGATGAAACGGACAATGCCGGGATACAGGGAGCGGCAGCCACAGCGGCTGCCATTCTGGACGGCATACCCTCGCTGAAGAAACGAAAATCTCTAACAGTCTATGGAAGGCACAATCCCACGGCGAACTCCTCCTCCTCCGCCGCCACCGCCGGTGGCTCATCCACGCTGCGGAAATTCAAGCCGAAACTGTACTTGCCGCTGGATATAGCGGTGCCACCACTGCCGCCGCTGCCCGTGACTGCTCCCGCTGCCGTTGCTCCTCCGTCTGCCCTACCCCTTCCACCCCCTCCTGCTCCGCCGCCGCCTCCGGCCGCCGGCGCCCCCAATCCTCCGCCTGCTGGCGTGCCTGGTGGCAGGGAGAGCTTGTCGGTGGCACTGCCACTGGATTTCAGCCAAGCTAGCTGCAGCAGCAGCAGCAGCAACAATCGCCTGTCCGGCCTCCTCCTCCAGCAGCAGCAACAGTCGGCTGCCGCAACTGGCGCTGCGCCACCTTCCGCTACCGCATCCGCATCCGCGTCCACGTCCACGTCCGCATCTGCTCCATTGCTCATGCCGCCACTGCCAGCGGTGCCCATCAAAGATGAGCCCATAGACACGGACGACGACTACCAGATGAAGTCGATTGACGAGTCCGACGACATGGTCGATCCCACAATGTTCCTAGAGCGCTCCGAGCACGAGGGCGACATGCCGTTGATGACCTCCGACTACGACTACACGGCCCAACATGGCGTCACCGCCGCCTCGGCAGCCGCCTCCCTGCCGGCCAATGCCGTCGCCAATGTGGCCGCTGCCGGCGACTCCAAGGTGGCCAGCTGCCGGGCCTGCAGCCTGCAGTTCTCCACGCGCGCCAATGCCCGTCGCCACGAACGCAACCTGCACCCCAATCTGTTCCAGCTCTCCACCGACTCGCCCCACAACACGCCCATCACCAAGCCCACGCCCGCCCTGGCCGCCGCCCTGGAGATCCAGCGGGCAGCCGCCGAGGCAGCCACCGCCGAGGCGAATCGAGCTGCCGGAGCGGCGGGCGGGAACATCTCCACCCAGAAGTACCGGCAGGTGGTGATGAACGCGTTTATCAAGTGCGAGGGCGGCGGCTACGACTACGAGAATCCGGAGCAGTACCGGGCGCACCTCACCCGCGACAAGGTGGAGTTCATCGAGCAGAACGAGGAGTTCCTCGAGCAGTACCAGACGATGACGTGCCGGTGCTGCAACAAGTACTTCAGCACCTACAAGAACTTCATGGCCCACGTCCGCAAGAAGTACCCGCTGCTGCCGCGCAACCTGTGCTTCAACTGCCTCAAGATGAACGACTCCAAGGCCCTGTTCATCTCCCACCTGAAGAAGAGGAACTGCATCAACCTGTACCGCGTGCTGCACGGCATCCGGGAGAAGGCCAACGCATCCGTCTCCAAGGACGCCACTCTGATCGAGGGGGGCGATGGGCGAGTTAGCCACCTGGATGCCGGCTCCAGTCCCAATGTGACCGGCGACGTCATCTCCAGTGCGGCCGGATCGGAGCGACCGGAGAAGCTGCGGGCCAAGGAGCTGCTGGTGAACAAGCTGTACGAGTGCAAGCTGTGCCCCAAGGGCTTCCGGACCAAGCACGAGTTCCGGACGCACGTCTACGACAAGCACGCGGACGTCCAGCGCAAGGACAGCAACTCGATCCAGTGCAACTTCTGCGGCCTGGACTTTGCCGACCCGGTGGACCGGCGGCGCCACTACAACAACATGGACTGCATCGTGCGCCTGCGCTGCATGACCTGCGACGCCAAGCTGGAGACGCACCAGCGCTTCCTCGAGCACGTCTACCAGGACCACCTGGGCGGCGTGGGCGGCGGCAGTGGCACCGGCGGCGGAGGCGCCAGCAGCGACAATGCCTCCACCACGGGCAACAGCATGGAGCACTCGCCGGGCAAGCGCAGCCTGCTCAGTGCCCTGGGCATCGGAGTGGGCTCCTCGGCGGACGAGTCGCGCAGCAGCAGTGTGGCCCTCGGGCCGATGACCTCCACGCCCAAGCCGGGCAATCAGCAGAATGCTTCTGCAGCTGCTACCGGCGGCGGCAATGGCTCTGCCCCGAAGTCGCAGTACTTCTCCCGCATGCCGCAGGTCTGCCCCATTTGCGGCCAGCAGTACAACAACTACAACAACGTGCTCCGGCACATGGAATCGAAGCATCCGAACAAGCTGCCGGAGACGTACAAGTGCGTGCGGTGCGGCCTGGGCTATCCGAGGATCTCGTACCTGCGGGAGCACATGATCAACGTGCACGGCGTGGACAAGAACCGGCACTCGGGCGGCTTCGAGTACATCGTGAACGCGGACGCCGTGAAGCTGGCGGACGGGAGCACCCCCAACGTGTACACCGGTCGCTACGACTACGTGATGAAGGACCTCATGTCGATAACAAATGGTGGGACCCTCGATGACGACGACGAGGAGCCGGGCAGCGTGGCCAAGAAGATGCGCCTGGACGACAGCAGCAACAACAGCAGCCTGGCCGGCGTGGGCGTTTCCAGCCAGCAGCAGCAGCAGCAGAAGGAGTGCCCCATCTGCAACGCCGTCTTCAGCAACAACATCGGCCTCTCCAACCACATGCGCTCCCACTACACGGCCTCCAACTCGGTGAACGCCGCCCTGACGGCGGCCAACCGGATGACGCCCAAGTCCCTGACCATAACGGCCACCCCGGCCGACACCAGCATGGACCTGCTAACTGGAGGCTCTTCCACGCCCGCGGCATCATCAGCGGCGGGTGTGCCGCCCGCCATGGCCAACCAGACGCCGCAGGAGCAGGCCGTGTTCCGGCGCAGCCTCGACCAGGCGGCCGACCGTCGGTTCCGGCGCATGCGCTGCCGCATCTGCCAGCGACGGTTCAGCTCGAAGAAGTCCTACCGCTACCACATGCTCACCGACCACCAGGTGCAGAACGTGCAGTTCATCAAGTGCAAGCTCTGCAACGCCGAGTTCGCCTACGAGAAGGGCCTCAAGGTGCATCTGTTCAAGGTGCACGGGCGGGCCATCAAGGACGAGATGATCGTGAAGCAGTTCGAGTGCGAGGTCTGCTCGATTGTGTACAGCTCCGAGATGGAGCTGCAGCAGCACAAGCGCAGTGTCCACAAGATGTCCTCCGCATCGGCAGCAGCGGCCGCCGCCTCCTCCTCCTCCTCGAAAATGGACGACGACAGCAGCATTGTCGTGGATGACAGCACCCTGAAGCCGGCGGGCGGCGACCTGACAGACACCTCCGTCAACGTTAGCCTGAGCACGCCGCTGTACTGGTACCAGTGCAAGTACTGCCCCTCCAACTTCAACACCAACAAGAAGCTGGCCATCCACATCAACTCGCACGACGAGTTCGACTCCAACGACTACTCCTGCAAGGACTGCGGCAATGTCTACAGTGGAAGGAAGAGTCTATGGGTCCATCGCTATAAGAAGCATCCACAGGTCCCAGACCCGGCAGAGTGCTCGCTCTGTCGCAAGATCTTCTTCGACCGCCAGATGCTGGACAATCACACGCCGACGTGCAACCGCAAGCCCATCACCTCAACGGGCGCCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTATTGCCCTCCAGAAGCAGGTGGGACTGCACTCTGGCATCTTCCGGCACAAGACCGGCGACGATGACGACGAGGATGACGAGGATGAGCAGCACCAGAAGCTGGCCGATGGAGCGGCCGACAGTGGAGCAGCTGCTTCTACGCCAGCTCCGGCCCCGGCCACCACAACGGCAACCTCGGCCGCCTCGATCAAGATACGCATTCCAGAGGTGGCGTGCACCATTTGCGGGGCCCGCTTCACCGACCAGGAGATGTTCACCAAGCACATCCAGAAGCACGAACAGGAACTGTACGTGGACAATCCCCTGGCGGCGATGTTCGACGATGGGCCGCCCGACGCCGGCCAGTTTCAGGTGGAGCTCGAGAAGCAGAACGAGAACGGGGAGTACGCGTGCGATCTGTGCGCGAAGACGTTCCCCCAGGTCATAGCACTCAAGGTGCACCGCAAGTGGCATTTCAGAGGTGATAGCAAGCAGAATCCCATCGACGGCGAAGCGACACATTTGACCAACAACAACCACACCACCAGCAACAACAACAACAGTCACAGCAGCAACAACAACAGTTCGATGTCGCACCTCCGGGAACTGCATGCGGTGGGCCTGATCCCCAACAACCAGCAGGCCCAGTCGGCGGCGGGCCACCAGCAGCAGCATCATCCTCAGCAGCAGCAGCAGCAGCCGGGCAACGCCAGCCTGGGGAGCAAGTCGATGAAGCGGAAGCGTGAACTGAAGTGCGAATACTGCCCCTCGACGTTCATCAGCAACAACAACCTGCGCCGGCACATGTACGAGCTGCACAAGCACGAGGTGAGCAACCTGCCGGAGCCGCCGGTCATTGTGGTGGACGACCATCTCTCCTGCCGCCGGTGCAACCTCAAGTTCGAGACGAAGGAGCTGTGGATCGACCACAAGCTGGCGGACGCCAAGGTGGTGCGGCCGTTCTGCCCCTTCCAGTGGGGCTGTGATCTGTGCGGCGAGTACCTGTCGCGCAAGGAGAAGCTGATGAATCACATCAACAACCATCTCAAGGAGGAGGTCATTGTGCCGGTGGCCACCAAGGAGGCGGCGGAGAGGGCGGCAGCAAAGCCGCAGGAGGCAGAGGCAGTAGCGGTATCGAATGCCACCGCTAAGCTGGAGGAGACAGATCAGAAGGCGGACGCCGGCAAGTCGGAGGGTAAGGCTCCGGCGGACAGCGATGATCTGGACGAGGAGGACAGCTCCGGTGAGGAGGAGACCTCTGGCACGGGCGATGACGAGGACGACGACGATGATGAGGAGGACTCGGAGGAGGATGTGGAGGACGAGGAGGACGACGAGGGCGATGGCGGCGAGGGCGAGGACGAGGAAGGCGTCCCCCCGCAGCAGCAGCCGCCCAAGATGAACCTCACCCAGGACGATGATCTGGTCGAGGAGGTGCTCAGCTCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTGGAAGAGCCCCAGCCGGTGGTGATGAACGGCAAGACGAAAATGCCGCCACTCATTGTGGCCACATCGGACGAGGAGGATGAGGAGGACGGCATGCTGCCCATCGAAGACATAATCGAGGAGGAATTCGACGAGGACGCCGCCGATCCGGAGCCCGAGGACGACATTGTTGAGGAGGACGAGGTTGAGGAGGAGGAGGAGGTAGATGAGGTGGAGGAGGAAGAGGTAATCGAAGAACTCGACGACGAGATGGACGAGGTGGGCAACGAAAGGCGCAACTCGTCGTCGGCCAGCGAGTCGAACACAACCGCCACCACCACGACCACGTCGCAGTCACATTCCACGGGTGAGCGGCACAAAAAGGTGCCGGAGGTGCCAGGCTTTACCTGTGATCTATGTCAACTTTGTTTCGATTCTCAGGAGCTTCTCCAGAGCCACATCAAAAGCCATTTTCTCAATGGGCCAAAGCTGGCCAAGGTCAAGGTGGTAGCCGGAGGAGGAGCAGCGGCAGCGGCAGCATCATCCTTAACAACGGAAGCGGTGCCTTCAAAGACGACATCGACAACGACGAGTACCAGTAGTAGCAGTAAGAGTAGTAAGCCACCAGCGGCTGCCACCAATGCTGCCACAGTCATCCTCCATCTCACTTGA
Protein Sequence: MMVMITPQDRLSLQICHACISYLNSWQSFKNRSLISQTKQRQWLEANNSSSIHKSKLLNYLDLNSAENGSASDNHHHQQQRQNQNQQHVLENEDETDNAGIQGAAATAAAILDGIPSLKKRKSLTVYGRHNPTANSSSSAATAGGSSTLRKFKPKLYLPLDIAVPPLPPLPVTAPAAVAPPSALPLPPPPAPPPPPAAGAPNPPPAGVPGGRESLSVALPLDFSQASCSSSSSNNRLSGLLLQQQQQSAAATGAAPPSATASASASTSTSASAPLLMPPLPAVPIKDEPIDTDDDYQMKSIDESDDMVDPTMFLERSEHEGDMPLMTSDYDYTAQHGVTAASAAASLPANAVANVAAAGDSKVASCRACSLQFSTRANARRHERNLHPNLFQLSTDSPHNTPITKPTPALAAALEIQRAAAEAATAEANRAAGAAGGNISTQKYRQVVMNAFIKCEGGGYDYENPEQYRAHLTRDKVEFIEQNEEFLEQYQTMTCRCCNKYFSTYKNFMAHVRKKYPLLPRNLCFNCLKMNDSKALFISHLKKRNCINLYRVLHGIREKANASVSKDATLIEGGDGRVSHLDAGSSPNVTGDVISSAAGSERPEKLRAKELLVNKLYECKLCPKGFRTKHEFRTHVYDKHADVQRKDSNSIQCNFCGLDFADPVDRRRHYNNMDCIVRLRCMTCDAKLETHQRFLEHVYQDHLGGVGGGSGTGGGGASSDNASTTGNSMEHSPGKRSLLSALGIGVGSSADESRSSSVALGPMTSTPKPGNQQNASAAATGGGNGSAPKSQYFSRMPQVCPICGQQYNNYNNVLRHMESKHPNKLPETYKCVRCGLGYPRISYLREHMINVHGVDKNRHSGGFEYIVNADAVKLADGSTPNVYTGRYDYVMKDLMSITNGGTLDDDDEEPGSVAKKMRLDDSSNNSSLAGVGVSSQQQQQQKECPICNAVFSNNIGLSNHMRSHYTASNSVNAALTAANRMTPKSLTITATPADTSMDLLTGGSSTPAASSAAGVPPAMANQTPQEQAVFRRSLDQAADRRFRRMRCRICQRRFSSKKSYRYHMLTDHQVQNVQFIKCKLCNAEFAYEKGLKVHLFKVHGRAIKDEMIVKQFECEVCSIVYSSEMELQQHKRSVHKMSSASAAAAAASSSSSKMDDDSSIVVDDSTLKPAGGDLTDTSVNVSLSTPLYWYQCKYCPSNFNTNKKLAIHINSHDEFDSNDYSCKDCGNVYSGRKSLWVHRYKKHPQVPDPAECSLCRKIFFDRQMLDNHTPTCNRKPITSTGAXXXXXXXXXXXXXXXXXXXXXXXXXXXXIALQKQVGLHSGIFRHKTGDDDDEDDEDEQHQKLADGAADSGAAASTPAPAPATTTATSAASIKIRIPEVACTICGARFTDQEMFTKHIQKHEQELYVDNPLAAMFDDGPPDAGQFQVELEKQNENGEYACDLCAKTFPQVIALKVHRKWHFRGDSKQNPIDGEATHLTNNNHTTSNNNNSHSSNNNSSMSHLRELHAVGLIPNNQQAQSAAGHQQQHHPQQQQQQPGNASLGSKSMKRKRELKCEYCPSTFISNNNLRRHMYELHKHEVSNLPEPPVIVVDDHLSCRRCNLKFETKELWIDHKLADAKVVRPFCPFQWGCDLCGEYLSRKEKLMNHINNHLKEEVIVPVATKEAAERAAAKPQEAEAVAVSNATAKLEETDQKADAGKSEGKAPADSDDLDEEDSSGEEETSGTGDDEDDDDDEEDSEEDVEDEEDDEGDGGEGEDEEGVPPQQQPPKMNLTQDDDLVEEVLSSXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXEEPQPVVMNGKTKMPPLIVATSDEEDEEDGMLPIEDIIEEEFDEDAADPEPEDDIVEEDEVEEEEEVDEVEEEEVIEELDDEMDEVGNERRNSSSASESNTTATTTTTSQSHSTGERHKKVPEVPGFTCDLCQLCFDSQELLQSHIKSHFLNGPKLAKVKVVAGGGAAAAAASSLTTEAVPSKTTSTTTSTSSSSKSSKPPAAATNAATVILHLT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00488153;
90% Identity: -
80% Identity: -