Basic Information

Insect: Drosophila auraria
Gene Symbol: -
Assembly: GCA_008042615.1
Location: VNJW01011138.1:103696-107625[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 7.3e-05 0.0073 16.9 0.4 1 23 173 196 173 196 0.96

2 14 0.0014 0.14 12.9 3.1 2 23 245 267 241 267 0.90

3 14 0.0074 0.73 10.6 0.2 1 23 363 386 363 386 0.92

4 14 0.016 1.6 9.6 3.3 2 23 435 456 434 457 0.94

5 14 0.00056 0.056 14.1 0.4 1 23 527 550 527 550 0.92

6 14 5.7 5.7e+02 1.6 0.1 2 14 569 581 568 593 0.83

7 14 0.00057 0.057 14.1 3.3 2 23 601 623 601 623 0.96

8 14 0.028 2.8 8.8 0.6 1 23 717 740 717 740 0.95

9 14 4.2e-05 0.0042 17.7 0.3 1 23 774 797 774 797 0.93

10 14 0.0036 0.36 11.6 1.5 2 23 847 869 846 869 0.95

11 14 0.015 1.5 9.6 1.8 1 23 964 987 964 987 0.91

12 14 0.0018 0.18 12.6 1.4 1 21 1039 1059 1039 1060 0.95

13 14 2.9 2.9e+02 2.5 0.1 3 23 1092 1115 1090 1115 0.75

14 14 2.8 2.8e+02 2.5 0.1 1 11 1133 1143 1133 1154 0.82

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	7.3e-05	0.0073	16.9	0.4	1	23	173	196	173	196	0.96
2	14	0.0014	0.14	12.9	3.1	2	23	245	267	241	267	0.90
3	14	0.0074	0.73	10.6	0.2	1	23	363	386	363	386	0.92
4	14	0.016	1.6	9.6	3.3	2	23	435	456	434	457	0.94
5	14	0.00056	0.056	14.1	0.4	1	23	527	550	527	550	0.92
6	14	5.7	5.7e+02	1.6	0.1	2	14	569	581	568	593	0.83
7	14	0.00057	0.057	14.1	3.3	2	23	601	623	601	623	0.96
8	14	0.028	2.8	8.8	0.6	1	23	717	740	717	740	0.95
9	14	4.2e-05	0.0042	17.7	0.3	1	23	774	797	774	797	0.93
10	14	0.0036	0.36	11.6	1.5	2	23	847	869	846	869	0.95
11	14	0.015	1.5	9.6	1.8	1	23	964	987	964	987	0.91
12	14	0.0018	0.18	12.6	1.4	1	21	1039	1059	1039	1060	0.95
13	14	2.9	2.9e+02	2.5	0.1	3	23	1092	1115	1090	1115	0.75
14	14	2.8	2.8e+02	2.5	0.1	1	11	1133	1143	1133	1154	0.82

Sequence Information

Coding Sequence: ATGGAAGGCATGGATCTGTGGACGTCGATGTTTTCCTCCGAGTTCGAGGACGGAGAGCCCGAAGGCGGCGAGGGAGAGCTGCTGGAGGGTGAGGATGGAGCGCCGTACGGCAACGGAAATGGCGACTTTCTCGACGACACGGAGATTCTAGAAGCTGGGGATGGTGTCGACGACCTGCTGGACGGCGAGGACGATGACcgggaggaggacgacgaaAACAGGCAAATGGATGGAGAGAAGGGGCCAAAGGGACCGGAGCCGGACGACGATGCTCTCTTCGACTTCGAGCTGGAGCCGATTGTGAGTATTGGGGAGTCGCAGCCGGCGGTTATGGCTCCTGCGGGTCCGATGGGTGCCCAAGTGCGTCCAACCCTGCAGCAGAGACACTCACTGCCTCCAGTAAGTAGGCCGCGATCCGATATGCGACCCATCGGGTTCCCCCTGCGGCCAACCACCTCGCAGATCAACGCCACCGATGAGAACGGCGTGCCCATCAACTACGAGCTGGGCGTGGTGTACATCTGTCCCGCCTGCGGTGGAGAGTTCCGGCAGCAGGATCACTGGAAGCGGCACATGAATCAAATCCACAGGTACAACACCCTCCGCGGCCTCAACTTTGCGCCGCTGGATAAGCTCTACCAGCGCTGCAAGGAGTGCCACAAGCGGATAGCCATGCACAGCCGGGAAAACCTGCTGAAGCACAAGTTCACGCACCTGCCGTTCCGGTGCACCAAGTGCTACATCTGCAAGCGGGAGTACAAATACAGACAAGATCTAATGGTGCACCTGCGCATGGTCCACTGCGACGAGGTGGTGGCCATGATGCGGGAGGGTTACAACGCGGCCGGACGCAAGACCCGAGTGCGGGAATCGCGCACCGAGCAGATGCGGCGCGAGGAGAGCTTCCTCGAGGATGAAGACCTGGATCGCATTGAGGTGCGAAACGAGGTGCTCGAGCCGGATGTTGACGAATCTGTAGGCATGGAGCAGCcgtcgctgccgccgccggtaGACGAGGCGCCGCCCAATAAGAAGCGAGCCGGCAGTGGAGGAGCAGCCGCCGAGCTGTGCGAAGACTACATCCACTTCATGTGCCCCGACTGCGGCACCGAGTGCGACACCCTGGCCCAGTGGAGCCAGCACATCGAGTTTGTCCACGACTATGTCAGCAGACGTGGCCTCAACTTCAGGAGCGTCGACATGCAGATGCAGTGCCTCGAATGCAAGAAGATTGTTACCCCCAACACCATCAAGTCGCTGCGCGCCCACAAATTCAGCCATCTCTCGCATCCCGAGTGGCTGCGCTGCAAGCTCTGCTACAAGGGCTACACGGATCATCAGGAACTGGTTATGCATCTGCTGAGGCACCATCATCTGGATACGCTGATGTCGGACGACgccgagcaggaggaggaggatgccCCACTGACCATTCCGGGGGATGTGAATGAAGGACAAGACAATGGAAATGGCGAGGGAAACGGCGCCGTGTTGGACGAGGATTCGCCCTACTTTGAGGACGCCCCCAGACGCGGCGGTCGCATCAGCAGCGACGACATCTTCGAGCCGCACATCGACTACCTGTGTCCGCAGTGCGGCAAGGAGTTCATCGAGAAGAAGCACTGGCGCACTCACGTGGTCATGGCGCACAGCATGAACGATTTGTCTAAGCTGAACTTCGAGATGATCAACGAGCGGCAGCTGAAGTGCACCGAGTGCGAGAAGATCATCACGAATGCGTATGGCATACAGAATGCCCAGCAGCACAGGATCACCCATCTGCCGTTCAAGGCGTATGCCAGATGCCGCAAGTGCCACAAGTCCTACACGGACAGGAAGGGTCTCGTCAAGCACCTGGCCACCTATCACCGCATCGGCTGTGATCCTCGAAAGTCCGGAGGAGTAGGTCTAGGAGCAGCACCCATACCGAGTACCCCCAAGCAGCCGCGCAAGCAGATCGTCACTGTGGCCAATGAGACCTACGAGATTATCTACCTGGACGATGTGGAGCAGAGCAGCATGGACGAGGAGAATGACTTTGGGGAGCAGATGCTGGCCGACGAGGACGATTACCCGATTGCTCCACCACCGCAACTAAGGcaggcgccgccgccgccgcgtaCTTCCTCGCAGAGCAACCAGCAGCGTTACAAGTGCGTCCACTGCAGCACTCTCTTTCCCACCCAAGTGGCCGTTCGGATACACATCAGCGAGAAGCATTGCCGGAAGCCCAACCAGATGGGCAGAAGACATCGACACTCGATGTCGAACGCTGGCGGGGCGGAGGCCGGGCTGAATACTGTAGAGCAGAACTACATCTTCCTGTGCCCGTCCTGCGGCAAGGAGTACAAGACGCAGTACGAGTGGCGTCGTCACATCAACGAGGAGCACAACTTCGACAAGAGGAACTATCTGAACATGCGGCAGTTGGATAAGTATCGCTACCAGTGCACTCAGTGCAAGGACATTGTCTGCAACTCCAAGCTGAAGGGTTTGCAGGACCACCACTTCCGTCACCTGCCATACCGCCTGTATCTCAAGTGCCTGGTCTGCGGCACCTGCTACAACCACAAGCCGAACATAGCCGCGCATCTGAGGGCCCGCCACAACATATTCGACAGGGAGACGCCCCTGATGGTCACCAAGCCGAAGCTCGTCTACCATCGCGGCAAGGACAGCAATAGGGAGAAAACCGCCCTGCCCTCTCCAGCTCCGGCAGCAGGATCTCCGCCCGGCTGCTCTTCCTCCGCCTCTGTTGCGCCCCCTACGCCTGTGCCCAATCGCACCCTCAAGCCGCAGCCCGGTGATCTGCCCACGCGACCCGCCGGCCTCAACACCCTGGAGGACAGCATCTCGTATCACAACGCCGTGGACATGGACTTCATCACGTACTTCTGCCCGAAGTGCAACCAGAACTTCGACTCGCACGCCTTCTGGCGCAAGCACATCGTGGAGCAGCACAACTTCAACAGCCGCGAGGGCCTGAACTTCCGTCAGATCGACAACCACCACTACCTGTGCCTGGAGTGCTACAAGCGCGTGACCGTGACCCACACCAAGGGCGCCATTGGCCAGCTGCAGTCGCACAAGTTCCGCCACCTGCCGCATCGCTCCTTCAAGTGTCTGACCTGTGACGCCTCCTTTGTGCGCAAGCAAATGTTCTTCAAGCACCTGAATCGCGACACCAACCGGTGTGACAATCGTCCCCAACGGGAGTTGGACGACGAGGAGCCGGGCGAGAACTCTCAGCTGCGCTCGATTTACCACCTGGCGTGTCCGCAGTGCGGCGATGACTTCAACACCCCCAGCCGGAAGCAGTGGCGCGAGCACATCAATGTCTTTCACGGCCTGGCCGAGCTGGACCTGCTGCACATGCACAAGGTAAGCGAGGACCTGTATCGCTGCCAGGACTGTGACGAGGAGCTGCAGACGAATCGGCAGTGGGTGCTGCTATACCACCGCTTCCAGCACCTGCCGCAACCAGCCTATGTTCGTTGCCAGCTGTGCGAGCAGAATAGCGAGAGGGATGCTTCAGTGGCAGCCGGGATGCATAGCCTGCgtgagctgcagcagcacctgCGCAAGCACCATCCCACGGTGGGCGAGAACGAGCTGATTGCGCTCGGCAACCAGATTGCCatcgaggagaaggagcaggagcagacaATGGGCGCGGTCGTGGACGATGAAGACAACCAGGCGGgtcaggaccaggaccaggactcGGGGCCCTACATGCCGCTTCCGCCGCATTTATTggacgatggcgacgacgtGGAGTTTGAGGACCAGTATCTGCTGGGATAG
Protein Sequence: MEGMDLWTSMFSSEFEDGEPEGGEGELLEGEDGAPYGNGNGDFLDDTEILEAGDGVDDLLDGEDDDREEDDENRQMDGEKGPKGPEPDDDALFDFELEPIVSIGESQPAVMAPAGPMGAQVRPTLQQRHSLPPVSRPRSDMRPIGFPLRPTTSQINATDENGVPINYELGVVYICPACGGEFRQQDHWKRHMNQIHRYNTLRGLNFAPLDKLYQRCKECHKRIAMHSRENLLKHKFTHLPFRCTKCYICKREYKYRQDLMVHLRMVHCDEVVAMMREGYNAAGRKTRVRESRTEQMRREESFLEDEDLDRIEVRNEVLEPDVDESVGMEQPSLPPPVDEAPPNKKRAGSGGAAAELCEDYIHFMCPDCGTECDTLAQWSQHIEFVHDYVSRRGLNFRSVDMQMQCLECKKIVTPNTIKSLRAHKFSHLSHPEWLRCKLCYKGYTDHQELVMHLLRHHHLDTLMSDDAEQEEEDAPLTIPGDVNEGQDNGNGEGNGAVLDEDSPYFEDAPRRGGRISSDDIFEPHIDYLCPQCGKEFIEKKHWRTHVVMAHSMNDLSKLNFEMINERQLKCTECEKIITNAYGIQNAQQHRITHLPFKAYARCRKCHKSYTDRKGLVKHLATYHRIGCDPRKSGGVGLGAAPIPSTPKQPRKQIVTVANETYEIIYLDDVEQSSMDEENDFGEQMLADEDDYPIAPPPQLRQAPPPPRTSSQSNQQRYKCVHCSTLFPTQVAVRIHISEKHCRKPNQMGRRHRHSMSNAGGAEAGLNTVEQNYIFLCPSCGKEYKTQYEWRRHINEEHNFDKRNYLNMRQLDKYRYQCTQCKDIVCNSKLKGLQDHHFRHLPYRLYLKCLVCGTCYNHKPNIAAHLRARHNIFDRETPLMVTKPKLVYHRGKDSNREKTALPSPAPAAGSPPGCSSSASVAPPTPVPNRTLKPQPGDLPTRPAGLNTLEDSISYHNAVDMDFITYFCPKCNQNFDSHAFWRKHIVEQHNFNSREGLNFRQIDNHHYLCLECYKRVTVTHTKGAIGQLQSHKFRHLPHRSFKCLTCDASFVRKQMFFKHLNRDTNRCDNRPQRELDDEEPGENSQLRSIYHLACPQCGDDFNTPSRKQWREHINVFHGLAELDLLHMHKVSEDLYRCQDCDEELQTNRQWVLLYHRFQHLPQPAYVRCQLCEQNSERDASVAAGMHSLRELQQHLRKHHPTVGENELIALGNQIAIEEKEQEQTMGAVVDDEDNQAGQDQDQDSGPYMPLPPHLLDDGDDVEFEDQYLLG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00609425;
90% Identity: iTF_00609425; iTF_00480459; iTF_00531947; iTF_00572177; iTF_00606642; iTF_00590525;
80% Identity: -