Basic Information

Insect: Drosophila rufa
Gene Symbol: -
Assembly: GCA_018153105.1
Location: JAECXS010000001.1:28332429-28336343[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 8.3e-05 0.0053 16.9 0.4 1 23 172 195 172 195 0.96

2 14 0.0016 0.1 12.9 3.1 2 23 244 266 240 266 0.90

3 14 0.0063 0.4 11.0 0.2 1 23 360 383 360 383 0.93

4 14 0.019 1.2 9.5 3.4 2 23 432 453 431 454 0.94

5 14 0.0013 0.081 13.2 0.4 1 20 524 543 524 547 0.88

6 14 6.4 4.1e+02 1.6 0.1 2 14 566 578 565 590 0.83

7 14 0.00064 0.041 14.1 3.3 2 23 598 620 598 620 0.96

8 14 0.032 2 8.8 0.6 1 23 710 733 710 733 0.95

9 14 4.8e-05 0.003 17.7 0.3 1 23 768 791 768 791 0.93

10 14 0.004 0.26 11.6 1.5 2 23 841 863 840 863 0.95

11 14 0.017 1.1 9.6 1.8 1 23 957 980 957 980 0.91

12 14 0.002 0.13 12.6 1.4 1 21 1032 1052 1032 1053 0.95

13 14 5.3 3.4e+02 1.8 0.3 3 23 1085 1108 1083 1108 0.83

14 14 3.2 2e+02 2.5 0.1 1 11 1126 1136 1126 1147 0.82

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	8.3e-05	0.0053	16.9	0.4	1	23	172	195	172	195	0.96
2	14	0.0016	0.1	12.9	3.1	2	23	244	266	240	266	0.90
3	14	0.0063	0.4	11.0	0.2	1	23	360	383	360	383	0.93
4	14	0.019	1.2	9.5	3.4	2	23	432	453	431	454	0.94
5	14	0.0013	0.081	13.2	0.4	1	20	524	543	524	547	0.88
6	14	6.4	4.1e+02	1.6	0.1	2	14	566	578	565	590	0.83
7	14	0.00064	0.041	14.1	3.3	2	23	598	620	598	620	0.96
8	14	0.032	2	8.8	0.6	1	23	710	733	710	733	0.95
9	14	4.8e-05	0.003	17.7	0.3	1	23	768	791	768	791	0.93
10	14	0.004	0.26	11.6	1.5	2	23	841	863	840	863	0.95
11	14	0.017	1.1	9.6	1.8	1	23	957	980	957	980	0.91
12	14	0.002	0.13	12.6	1.4	1	21	1032	1052	1032	1053	0.95
13	14	5.3	3.4e+02	1.8	0.3	3	23	1085	1108	1083	1108	0.83
14	14	3.2	2e+02	2.5	0.1	1	11	1126	1136	1126	1147	0.82

Sequence Information

Coding Sequence: ATGGAAGGCATGGATCTGTGGACGTCGATGTTTTCCTCCGAGTTCGAGGACGGAGAGCCGGAAGGCGGCGAGGGAGAGCTGCTGGAGGGTGAGGATGGAGCGCCGTACGGCAACGGCAATGGCGACTTTCTCGACGACACGGCGATTCTGGAGGCCGGGGATGGTGTCGACGACCTGCTGGACGGCGAGGACGATGACCGGGAGGAGGACGACGACGAAAACAGGCAGATGGATGGGGAGAAGGGGCCAAAGGGACCGGAGCCGGACGACGATGCTCTCTTTGACTTTGAGCTGGAGCCGATTGTGAGTATGGGGGAGCCGCAGCCGCCGGTTATGGCTCCCGCCGGTCCAATGGGCGCCCAAGTGCGCCCCGCCCTGCTGCAGCGGCACTCACTGCCGCCAGGGAGTAGGCCGCGGTCCGGACCCATTGGGTTCCCGGTGCGGCCAACCACCTCGCAGATCAACGCCACCGATGAGAACGGCGTGCCCATCAACTACGAGCTGGGCGTGGTGTACATCTGTCCCGCCTGCGGCGGCGAGTTCCGGCAGCAGGATCACTGGAAGCGGCACATGAACCAAATCCACAGATACAACACCCTGCGCGGCCTCAACTTTGCGCCGCTGGACAAGCTCTACCAGCGCTGCAAGGAGTGCCACAAGCGGATAGCCATGCACAGCCGGGAGAACCTGCTGAAGCACAAGTTCACGCACCTTCCCTTCCGCTGCACCAAGTGCTACATCTGCAAAAGGGAGTACAAATACAGGCAAGATCTAATGGTGCACCTGCGCATGGTGCACTGCGACGAGGTGGTGGCCATGATGCGGGAGGGTTACAATGCGGCCGGACGCAAGACCCGGGTGCGGGAATCGCGCACCGAGCAGATGCGGCGGGAGGAGAGCTTCCTCGAGGATGAGGACCTGGATCGCATCGAGGTAAGGAACGAGGTGCTCGAGCCGGACGTTGACGATGCTGGAGGCATGGAGCAAACGCCGCTGGTGGAGGAGGCGCCGCCCCCTAAGAAGCGACGCGGCGGCAGTGGAGGGGGCGCCGCCGAGCTGTGCGAGGACTACATCCACTACATGTGCCCCGACTGCGGCACCGAGTGCGACACCCTGGCCCAGTGGAGCCAGCACATCGAGTTTGTCCACGACTATGTCAGCAGGCGCGGGCTCAACTTTCGGAGCGTGGACATGCAGATGCAGTGCCTCGAGTGCAAGAAGATTGTCACCCCCAACACCATCAAGTCGCTGCGCGCCCACAAATTCAGCCATCTGTCGCATCCCGAGTGGCTGCGCTGCAAGCTCTGCTACAAGGGCTACACGGATCACCAGGAGCTGGTCATGCATCTGCTGAAGCACCATCATCTGGACACGCTGATGTCGGATGATCCCGAGCAGGAGGAGGAGGAGGAGGATGCCCCACTGACCAGGGATCCAAATGAAAGCGAAGACCATGGCAATGGCGAGGGAAACGGCGCCGTGTTGGACGAGGATTCACCCTACTTTGAGGACGCTCCGAGACGCGGCGGCCGGATCAGCAGCGACGACATCTTCGAGCCGCACATCGACTACCTGTGTCCGCAGTGCGGCAAGGAGTTCATCGAGAAGAAGCACTGGCGCGCGCACGTGGTCTTTGCGCACAACATGAACGATCTGTCCAAGCTGAACTTCGAGATGATCAACGAGCGGCAGCTGAAGTGCACCGAGTGCGAGAAGATCATCACGAATGCGTACGGCATACAGAATGCCCAGCAGCACAGGATCACGCATCTCCCATTCAAGGCCTATGCCAGGTGCCGCAAGTGCCACAAGTCCTACACGGACAGGAAGGGTCTGGTCAAGCACCTGGCCACCTATCACCGCATAGGCTGTGATCCCCGAAAGTCAGCAGGCGGAGGAGCAGCTCCAGCGCCACCCAAGCAGCCGCGCAAGCAGATCGTCACGGTGGCCAATGAGACGTACGAGATCATCTACCTGGACGATGTGGAGCAGAGCAGCATGGACGAGGAGAATGACTTTGGGGAGCAGATGCTGGCCGACGAGGACGATTACCCGCTGGCTGCACCTCCCCAACTGAGGCAGGCGCCGCCTCCACCTCGACCCTCTCCGCAGAACAACCAGCAGCGCTACAAGTGCGTCCACTGCAGCACCCTCTTTCCCACCCAGGTGGCCGTGCGGATCCACATCAGCGAGAAGCACTGCCGCAAGCCCAACCAGGTGGGCCGAAGGCATCGGCACTCGCTGTCGAACGCGGGCGGAGGAGCGGAGCCCGGGCTGAATACCGTGGAGCAGAACTACATCTTCCTGTGCCCGTCCTGCGGCAAGGAGTACAAGACGCAGTACGAGTGGCGGCGCCACATCAACGAGGAGCACAACTTCGACAAGCGGAACTACCTGAACATGCGGCAGCTGGACAAGTATCGCTACCAGTGCACCCAGTGCAAGGACATTGTCTGCAACTCGAAGCTGAAGGGTCTGCAGGACCACCACTTCCGCCACCTGCCATACCGCCTGTATCTCAAGTGCCTCGTCTGCGGCACCTGCTACAACCACAAGCCGAACATAGCCGCCCACCTGAGGGCCCGCCACAACATCTTCGACAGGGAGACGCCGCTGATGGTCACCAAGCCGAAGCTCGTCTACCATCGCAGCAAGGAGGGCGCTGGAGAGAAGTCGGCTTTAACCTCTCCCGCTCCGGCAGCAGGCTCCCCACCAGGCTGCTCCTCCTCATCTGTTGCTCCTCCCACGCCCACGCCCAATCGCACCCTGAAGCCGCAGCCCGGGGACCTGCCCACGCGACCCGCCGGCCTCAACACCCTGGAGGACAGCATCTCGTACCACAACGCCGTGGACATGGACTTCATCACGTACTTCTGCCCGAAGTGCAACCAGAACTTCGACTCGCACGCCTTCTGGCGCAAGCACATCGTGGAGCAGCACAACTTCAACAGCCGCGAGGGCCTGAACTTCCGCCAGATCGACAACCACCACTACCTGTGCCTCGAGTGCTACAAGCGCGTGACCGTCACCCACACCAAGGGCGCCATTGGCCAGCTGCAGTCGCACAAGTTCCGCCATCTCCCCCATCGCTCCTTCAAGTGTCTCACCTGCGACGCCTCCTTTGTGCGCAAGCAGATGTTCTTCAAGCACCTGAACCGTGACACCAATCGCTGCGACAATCGTCCCCAGCGGGAGTTGGACGACGAGGAGCCCAGCGAGAGCTCCCAGCTAAGCTCCATCTACCACCTGGCGTGCCCGCAGTGCGGCGATGACTTCCACACCCCCAGCCGGAAGGAGTGGCGCGAGCACATCAATGTCTTCCACGGCCTGGCCGAGCTGGATCTGCTGCACATGCACAAGGTCAGCGAGGATCTCTACCGCTGCCAGGACTGCGACGAGGAGCTGCAGACGAACCGGCAGTGGGTGCTGCTCTACCACCGCTTCCAGCATCTGCCGCAGCCAGCCTACGTTCGCTGCCAGCTGTGCGAGCAGAACACGGAGCGGGATGCATCAGTGGCGTTGTGGATGTATAGCCTGCGCGAGCTGCAGCAGCATCTCCGCAAGCACCATCCCACGGTGGGCGAGAACGAGATGTTTGCGCTCGGCAACCAGATTGCCCGCGAGGAGAAGGAGCAGGAGCAGACCATGGGCGCGGTCGGAGACGATGAAGACAACCAGACGGGCCAGGAGCAGGAGCAGGACCAGGACCAGGACTCGGGGCCCTACATGCCGCTGCCGCCGCATTTACTGGACGATGGCGACGACGTGGAGTTCGAGGACCAGTATCTGCTGGGCTAG
Protein Sequence: MEGMDLWTSMFSSEFEDGEPEGGEGELLEGEDGAPYGNGNGDFLDDTAILEAGDGVDDLLDGEDDDREEDDDENRQMDGEKGPKGPEPDDDALFDFELEPIVSMGEPQPPVMAPAGPMGAQVRPALLQRHSLPPGSRPRSGPIGFPVRPTTSQINATDENGVPINYELGVVYICPACGGEFRQQDHWKRHMNQIHRYNTLRGLNFAPLDKLYQRCKECHKRIAMHSRENLLKHKFTHLPFRCTKCYICKREYKYRQDLMVHLRMVHCDEVVAMMREGYNAAGRKTRVRESRTEQMRREESFLEDEDLDRIEVRNEVLEPDVDDAGGMEQTPLVEEAPPPKKRRGGSGGGAAELCEDYIHYMCPDCGTECDTLAQWSQHIEFVHDYVSRRGLNFRSVDMQMQCLECKKIVTPNTIKSLRAHKFSHLSHPEWLRCKLCYKGYTDHQELVMHLLKHHHLDTLMSDDPEQEEEEEDAPLTRDPNESEDHGNGEGNGAVLDEDSPYFEDAPRRGGRISSDDIFEPHIDYLCPQCGKEFIEKKHWRAHVVFAHNMNDLSKLNFEMINERQLKCTECEKIITNAYGIQNAQQHRITHLPFKAYARCRKCHKSYTDRKGLVKHLATYHRIGCDPRKSAGGGAAPAPPKQPRKQIVTVANETYEIIYLDDVEQSSMDEENDFGEQMLADEDDYPLAAPPQLRQAPPPPRPSPQNNQQRYKCVHCSTLFPTQVAVRIHISEKHCRKPNQVGRRHRHSLSNAGGGAEPGLNTVEQNYIFLCPSCGKEYKTQYEWRRHINEEHNFDKRNYLNMRQLDKYRYQCTQCKDIVCNSKLKGLQDHHFRHLPYRLYLKCLVCGTCYNHKPNIAAHLRARHNIFDRETPLMVTKPKLVYHRSKEGAGEKSALTSPAPAAGSPPGCSSSSVAPPTPTPNRTLKPQPGDLPTRPAGLNTLEDSISYHNAVDMDFITYFCPKCNQNFDSHAFWRKHIVEQHNFNSREGLNFRQIDNHHYLCLECYKRVTVTHTKGAIGQLQSHKFRHLPHRSFKCLTCDASFVRKQMFFKHLNRDTNRCDNRPQRELDDEEPSESSQLSSIYHLACPQCGDDFHTPSRKEWREHINVFHGLAELDLLHMHKVSEDLYRCQDCDEELQTNRQWVLLYHRFQHLPQPAYVRCQLCEQNTERDASVALWMYSLRELQQHLRKHHPTVGENEMFALGNQIAREEKEQEQTMGAVGDDEDNQTGQEQEQDQDQDSGPYMPLPPHLLDDGDDVEFEDQYLLG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00492530;
90% Identity: iTF_00483241;
80% Identity: -