Basic Information

Gene Symbol
-
Assembly
GCA_008042795.1
Location
VNJZ01013800.1:3035-6968[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 14 8e-05 0.0073 16.9 0.4 1 23 177 200 177 200 0.96
2 14 0.0016 0.14 12.9 3.1 2 23 249 271 245 271 0.90
3 14 0.008 0.73 10.6 0.2 1 23 366 389 366 389 0.92
4 14 0.019 1.7 9.5 3.4 2 23 438 459 437 460 0.94
5 14 0.0012 0.11 13.2 0.4 1 20 530 549 530 553 0.88
6 14 6.8 6.2e+02 1.4 0.0 2 13 572 583 571 588 0.81
7 14 0.00062 0.057 14.1 3.3 2 23 604 626 604 626 0.96
8 14 0.031 2.8 8.8 0.6 1 23 716 739 716 739 0.95
9 14 4.6e-05 0.0042 17.7 0.3 1 23 774 797 774 797 0.93
10 14 0.0039 0.35 11.6 1.5 2 23 847 869 846 869 0.95
11 14 0.017 1.5 9.6 1.8 1 23 964 987 964 987 0.91
12 14 0.0019 0.17 12.6 1.4 1 21 1039 1059 1039 1060 0.95
13 14 5.1 4.6e+02 1.8 0.3 3 23 1092 1115 1090 1115 0.83
14 14 9.8 8.9e+02 0.9 0.0 1 10 1133 1142 1133 1150 0.79

Sequence Information

Coding Sequence
ATGGAAGGAATGGATCTGTGGACGTCGATGTTTTCCTCCGAGTTCGAGGACGGAGAGCCGGAAGGCGGCGAGGGAGAGCTGCTGGAGGGTGAGGATGGAGCGCCgtacggcaacggcaacggcaatggcgatggcgacTTTCTCGACGACACGGCGATTCTGGAGGCCGGGGATGGTGTCGACGACCTGCTGGATGGCGAGGACGATGAccgggaggaggaggacgacgaaaACAGGCAGATGGATGGGGAGAAGGGGCCAAAGGGACCGGAGCCGGACGACGATGCTCTCTTTGACTTTGAGCTGGAGCCGATTGTGAGTATGGGGGAGGAGCCGCAGCCGGCGGTTATGGCTCCCGCCGGTCCAACGGGCGCCCAAGTGCGTCCCGCCCTGCAGCAGCGACACTCACTGCCGCCAGTGAGTAGGCCACGGTCCGGACCCATTGGGTTCCCGGTGCGGCCAACCACCTCGCAGATCAACGCCACCGATGAGAACGGCGTGCCCATCAACTACGAGCTGGGCGTGGTGTACATCTGTCCAGCCTGCGGCGGAGAGTTCCGGCAGCAGGATCACTGGAAGCGGCACATGAACCAAATCCACAGATACAACACCCTGCGCGGCCTCAACTTTGCGCCGCTGGACAAGCTCTACCAGCGCTGCAAGGAGTGCCACAAGCGGATAGCCATGCACAGCCGGGAGAACCTGCTGAAGCACAAGTTCACGCACCTTCCCTTCCGCTGCACCAAGTGCTACATCTGCAAAAGGGAGTACAAATACAGGCAAGATCTAATGGTGCACCTGCGCATGGTCCACTGCGACGAGGTGGTGGCCATGATGCGGGAGGGTTACAATGCGGCCGGACGCAAGACTCGGGTGCGGGAGTCGCGCACCGAGCAGATGCGGCGGGAGGAGAGCTTCCTCGAGGATGAGGACCTGGATCGCATCGAGGTGCGAAACGAGGTGCTCGAGCCGGACGTTGACGATGCTGGAGGCATGGAGCAACTGCCGCCGCCGGTGGAGGAGGCGCCGCCCCCTAAGAAGCGACGCGGCGGCAGTGGAGGAGGCGCCGCCGAGCTGTGCGAGGACTACATCCACTTCATGTGCCCCGACTGCGGCACCGAGTGCGACACCCTGGCCCAGTGGAGTCAGCACATTGAGTTTGTCCACGACTATGTGAGCAGGCGCGGGCTCAACTTTCGGAGCGTGGACATGCAGATGCAGTGCCTCGAGTGCAAGAAGATTGTCACCCCCAACACCATCAAGTCGCTGCGTGCCCACAAATTCAGCCATCTGTCGCATCCCGAGTGGCTGCGCTGCAAGCTCTGCTACAAGGGCTACACGGATCACCAGGAGCTGGTCATGCATCTGCTGAAGCACCATCATCTGGACACGCTGATGTCGGATGATCccgagcagcaggaggaggaggacgatgcTCCACTGTCTAGGGATCCAAATGTAAGCGAAGACCATGGCAATGGCGAGGGAAACGGCGCCGTGTTGGACGAGGATTCGCCCTACTTTGAGGACGCTCCGAGACGCGGCGGCCGGATCAGCAGCGACGACATCTTCGAGCCGCACATCGACTACCTGTGTCCGCAGTGCGGCAAGGAGTTCATTGAGAAGAAGCACTGGCGCGCGCACGTGGTTTTTGCGCACAGCATGAACGATCTGACCAAGCTGAACTTCGAGATGATCAACGAGCGGCAGCTGAAGTGCACCGAGTGCGAGAAGATCATCACGAATGCGTACGGCATACAGAATGCCCAGCAGCACAGGATCACCCATCTCCCGTTCAAGGCCTATGCCAGGTGCCGCAAGTGCCACAAGTCCTACACGGACCGGAAGGGTTTGGTCAAGCACCTGGCCACCTATCACCGCATAGGCTGTGATCCCCGAAAGTCAGtaggcggaggagcagcaccagTGCCACCCAAGCAGCCGCGCAAGCAGATCGTCACGGTGGCCAATGAGACATACGAGATTATCTACCTGGACGATGTGGAGCAGAGCAGCATGGACGAGGAGAATGACTTTGGGGAGCAGATGCTGGCCGACGAGGACGATTACCCGCTGGCTCCAGCTCCCCAACTGAGGCAGGCGCCGCCTCCACCTCGACCCTCCCCGCAGAACAACCAGCAGCGCTACAAGTGCGTCCACTGCAGCACCCTCTTTCCCACCCAGGTGGCCGTGCGGATCCACATCAGCGAAAAGCACTGCCGGAAGCCCAACCAGGTGGGCCGAAGGCATCGGCACTCGCTGTCGAACGCGGGAGGAGGAGCGGAGCCTGGGCTGAACACGGTGGAGCAGAACTACATCTTCCTGTGCCCGTCCTGCGGCAAGGAGTACAAGACGCAGTACGAGTGGCGGCGCCACATCAACGAGGAGCACAACTTCGACAAGCGGAACTACCTGAACATGCGGCAGCTGGACAAGTATCGCTATCAGTGCACCCAGTGCAAGGACATTGTCTGCAACTCGAAGCTGAAGGGTCTGCAGGACCACCACTTCCGCCACCTGCCATACCGCCTGTATCTCAAGTGCCTCGTCTGCGGCACCTGCTACAACCACAAGCCGAACATAGCCGCCCATCTGAGGGCGCGCCACAACATCTTCGACAGGGAGACGCCGCTGATGGTCACCAAGCCGAAGCTCGTCTACCATCGCAGCAAGGAAGGGGATAGGGAGAAGGCGGCCTTAACCTCGCCCGCTCCGGCAGCAGGCTCCCCACCCGGCTGCTCATCCTCCTCTGTTGCGGCTCcccccacgcccacgcccaatCGCACCCTGAAGCCGCAGCCCGGGGACCTGCCCACGCGACCCGCCGGCCTCAACACCCTGGAGGACAGCATCTCGTACCACAACGCCGTGGACATGGACTTCATCACGTACTTCTGCCCGAAGTGCAACCAGAACTTCGACTCGCACGCCTTCTGGCGCAAGCACATCGTGGAGCAGCACAACTTCAACAGCCGCGAGGGCCTGAACTTCCGCCAGATCGACAACCACCACTACCTGTGCCTCGAGTGCTACAAGCGCGTGACCGTCACCCACACCAAGGGCGCCATTGGCCAGCTGCAGTCGCACAAGTTCCGCCATCTCCCGCACCGCTCCTTCAAGTGTCTCACCTGCGACGCCTCCTTTGTGCGCAAGCAGATGTTCTTCAAGCACCTGAATCGCGATACCAATCGCTGTGACAATCGTCCCCAGCGGGAGTTGGACGACGAGGAGCCGAGTGAGAGCTCCCAGCTAAGCTCCATCTACCACCTGGCGTGTCCGCAGTGCGGCGATGACTTCCACACACCCAGCCGGAAGGAGTGGCGCGAGCACATCAATGTCTTCCACGGCCTGGCCGAGCTGGATCTGCTGCACATGCACAAGGTAGGCGAGGATCTCTACCGCTGCCAGGActgcgaggaggagctgcagacGAATCGGCAGTGGGTGCTGCTCTACCACCGCTTCCAGCATCTCCCGCAGCCAGCCTACATTCACTGCCAGCTGTGCGAGCAGAACACGGAGCGGGATGCATCAGTGGCGTCGTGGATGTATAGCCTGCgcgagctgcagcagcatctTCGCAAGCACCATCCCACGGTGGGCGAGAACGAGATGTTTGCGCTCGGCAACCAGATTGCCcgcgaggagaaggagcaggagcagatcATGGGTGCGGTCGGAGACGATGAAGACAACCAGACGGgtcaggaccaggaccaggagcaggaccaggactCGGGGCCCTAcatgccgctgccgccgcatTTACTGGACGATGGCGACGACGTGGAGTTCGAGGACCAGTATCTGCTGGGCTAG
Protein Sequence
MEGMDLWTSMFSSEFEDGEPEGGEGELLEGEDGAPYGNGNGNGDGDFLDDTAILEAGDGVDDLLDGEDDDREEEDDENRQMDGEKGPKGPEPDDDALFDFELEPIVSMGEEPQPAVMAPAGPTGAQVRPALQQRHSLPPVSRPRSGPIGFPVRPTTSQINATDENGVPINYELGVVYICPACGGEFRQQDHWKRHMNQIHRYNTLRGLNFAPLDKLYQRCKECHKRIAMHSRENLLKHKFTHLPFRCTKCYICKREYKYRQDLMVHLRMVHCDEVVAMMREGYNAAGRKTRVRESRTEQMRREESFLEDEDLDRIEVRNEVLEPDVDDAGGMEQLPPPVEEAPPPKKRRGGSGGGAAELCEDYIHFMCPDCGTECDTLAQWSQHIEFVHDYVSRRGLNFRSVDMQMQCLECKKIVTPNTIKSLRAHKFSHLSHPEWLRCKLCYKGYTDHQELVMHLLKHHHLDTLMSDDPEQQEEEDDAPLSRDPNVSEDHGNGEGNGAVLDEDSPYFEDAPRRGGRISSDDIFEPHIDYLCPQCGKEFIEKKHWRAHVVFAHSMNDLTKLNFEMINERQLKCTECEKIITNAYGIQNAQQHRITHLPFKAYARCRKCHKSYTDRKGLVKHLATYHRIGCDPRKSVGGGAAPVPPKQPRKQIVTVANETYEIIYLDDVEQSSMDEENDFGEQMLADEDDYPLAPAPQLRQAPPPPRPSPQNNQQRYKCVHCSTLFPTQVAVRIHISEKHCRKPNQVGRRHRHSLSNAGGGAEPGLNTVEQNYIFLCPSCGKEYKTQYEWRRHINEEHNFDKRNYLNMRQLDKYRYQCTQCKDIVCNSKLKGLQDHHFRHLPYRLYLKCLVCGTCYNHKPNIAAHLRARHNIFDRETPLMVTKPKLVYHRSKEGDREKAALTSPAPAAGSPPGCSSSSVAAPPTPTPNRTLKPQPGDLPTRPAGLNTLEDSISYHNAVDMDFITYFCPKCNQNFDSHAFWRKHIVEQHNFNSREGLNFRQIDNHHYLCLECYKRVTVTHTKGAIGQLQSHKFRHLPHRSFKCLTCDASFVRKQMFFKHLNRDTNRCDNRPQRELDDEEPSESSQLSSIYHLACPQCGDDFHTPSRKEWREHINVFHGLAELDLLHMHKVGEDLYRCQDCEEELQTNRQWVLLYHRFQHLPQPAYIHCQLCEQNTERDASVASWMYSLRELQQHLRKHHPTVGENEMFALGNQIAREEKEQEQIMGAVGDDEDNQTGQDQDQEQDQDSGPYMPLPPHLLDDGDDVEFEDQYLLG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00492530;
90% Identity
iTF_00483241;
80% Identity
-