Basic Information

Insect: Drosophila ambigua
Gene Symbol: -
Assembly: GCA_018150905.1
Location: JAECWS010000001.1:2299936-2306278[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 0.00061 0.041 14.1 1.5 1 23 147 169 147 169 0.97

2 15 3.6 2.4e+02 2.3 0.8 1 23 175 198 175 198 0.89

3 15 5.8e-06 0.00039 20.5 0.5 1 23 385 407 385 407 0.98

4 15 7.3 4.9e+02 1.3 3.8 1 23 413 436 413 436 0.93

5 15 0.1 6.9 7.1 0.8 1 23 453 476 453 476 0.93

6 15 0.0038 0.26 11.6 2.1 5 23 775 793 772 793 0.92

7 15 0.043 2.9 8.3 1.4 1 23 799 822 799 822 0.98

8 15 6 4e+02 1.6 1.3 2 19 862 880 858 882 0.56

9 15 0.00084 0.057 13.7 0.7 1 23 902 925 902 925 0.97

10 15 0.0023 0.16 12.3 0.4 1 23 1182 1205 1182 1205 0.91

11 15 0.011 0.74 10.2 3.2 1 23 1217 1239 1217 1239 0.98

12 15 2.6e-05 0.0018 18.4 1.7 1 23 1244 1267 1244 1267 0.95

13 15 0.0018 0.12 12.6 3.8 1 23 1273 1298 1273 1298 0.95

14 15 0.0023 0.16 12.3 5.1 1 23 1303 1325 1303 1325 0.97

15 15 0.00095 0.064 13.5 0.8 1 23 1331 1354 1331 1355 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	0.00061	0.041	14.1	1.5	1	23	147	169	147	169	0.97
2	15	3.6	2.4e+02	2.3	0.8	1	23	175	198	175	198	0.89
3	15	5.8e-06	0.00039	20.5	0.5	1	23	385	407	385	407	0.98
4	15	7.3	4.9e+02	1.3	3.8	1	23	413	436	413	436	0.93
5	15	0.1	6.9	7.1	0.8	1	23	453	476	453	476	0.93
6	15	0.0038	0.26	11.6	2.1	5	23	775	793	772	793	0.92
7	15	0.043	2.9	8.3	1.4	1	23	799	822	799	822	0.98
8	15	6	4e+02	1.6	1.3	2	19	862	880	858	882	0.56
9	15	0.00084	0.057	13.7	0.7	1	23	902	925	902	925	0.97
10	15	0.0023	0.16	12.3	0.4	1	23	1182	1205	1182	1205	0.91
11	15	0.011	0.74	10.2	3.2	1	23	1217	1239	1217	1239	0.98
12	15	2.6e-05	0.0018	18.4	1.7	1	23	1244	1267	1244	1267	0.95
13	15	0.0018	0.12	12.6	3.8	1	23	1273	1298	1273	1298	0.95
14	15	0.0023	0.16	12.3	5.1	1	23	1303	1325	1303	1325	0.97
15	15	0.00095	0.064	13.5	0.8	1	23	1331	1354	1331	1355	0.95

Sequence Information

Coding Sequence: ATGGCGTCTAACAATAGGTTGAAAACGGGCCCAGGCTCAGGCTCAGGATTATCCCAAATAAACTACAAATTTACATGTCGCTGCTGTCTGAAATCCGATGCGGAGTTCCTCAAACTGGACACGCTGGCGGTGGCGCGCAATCTAGATCCAAGCGAATCGGATAAAATTCCCCTGCTGCGTTGTTTGCTATTCTGCATACGCGCCGAAAACTCGCCGGAGCTGCCACAATACATATGCGTTGAGTGTAGCAAGAGTTTGCAAATAGCCTACTACTTCCTGCAGAATGCACTGCGTGCACACGAAATACTCTGCCGCAAACTGTGTCCGGGAAAGGCCCGTTCCACGCTGGCGCATCGCTACAACGGGTCCATCAAACAGCCAGAGGCGGCGCTGCGGCAGCCGGGTGAGGACAAGACGAAGCCCCAAAAGGCATTCCGGCACGAGTGCAAACTCTGCGGCTTTGTCGTCTACAATCGGATGGAGCTAAAGCAGCACATACGCCAGCACGTTGATGGCAGCTCCTACAGCTGCAAAGTCTGCAGCTTCGTTACGCTGAAGCAGCGTCTCTTGCAGGAGCATTATAGTGCTACCCATGGCATGTCGGCCAACCAGGCGGACGGTCGAGTGAAACCGAAATCTACATTCTACAGTGCCGGCCCCTCCACTTCATCCGCGGCTGCTGCTGTCGAGAAGGAGGTTAAAGTGTGCACCCTGGAGGACATGGAGCTGCTGATTCCCACAGTTCTCACGCCCGGTGACTATGTCCAACCGGCCATGGACGAGGAGCAACTGCGCGACATTGAACAGCAGCTGGCCGCCAGCATGGGGGAGCCTGTGGCTGCTGGTGCTGGCGCTTTGACCACCAATCTGAAACAAATGCAGTGCAAAAATATGAGCATTGGCAGCGAATATGTCGTCATGCCCGATGGGACCTTGCAGATAAACGGAGGCGCAGGCGTGGTGATAGAATACATCGATGACAGCAGGCCAAACAGCAACACCACTGGAAATTTGAGCCTTCAAAATCTTCTTGGAGGTGATGCCGAAAACGAGCCAATGGACATCGATGTTAGTGAACTCATTGTGGAGGAAATGCTGCCGCAGATAAAAGTCAAGCCAAAACCAATAGCCATTGGACCCGCTCCCCTCAAGTACAAATGCAAAGACTGTCCCAAAGCATTTGCCACCCTGGGGCGTCTGAAATCTCACCAGTTGAGCCACAGCCATTTGCCCAAGTTCTACTGCGATCAGTGCCCCTTCTACTCGCTGCGCAGTACCGATCTCTGTCTGCACTACAAGACAACGCATCTCAAGAGCGATGAGATTCGAAAGCTGGCCGGCGATGAATCGCAAACTTATTCCTGCGACATGTGCCTCTTCGAAGGGAAGACCTCCAGCCAGCTGCGGGTGCACTACACTGAGAAGCATATGATTCAACCATCGGAGGTACAGCTGCGTCCCAGTTGGACAAGTGAGTCGGACACCGTCGGTGACGGCATCAGTTCGGCTCGCACCAGCGGCCAAGGCTCCAAGGAGCAGGGCGCTCAGCCGCAGCACACCGAAATTCCACTGGGCATTCAATATCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNACGCAGTCGGGCGAAATCAATGTGGTGGTAGATGCCACACCGTTGTTCTATGCGGCGACAGTAGCAGGGACTGACACTGGGGCAGTGGCAGCGGGACAAGGACAGGGACAGGGAGATCCGGGTACAATAGCCGCTGAAGCAATGGCCAACGGGGACACGTATGAAATATTTCCAGAAATCTCAACGAGCAGTCTGACAGCGACACAGCCCGTACCGGCGTTGCCAACGCCGACGACGTCGGCGAACATCTCCATGTTTGGGGATATGCAGGATTTTATTGACAACACAGATGTGGCCGCCATATGCACCATACCCGCCGATGATATGCCCGTGGTGGATGGTGACGATATTGTGATTGACAACAACAATATCAGCTTAGACTTTGATGCTGAGAATCTGTTTGAGGAGTTTGATGATGAGGACGAGGCCGTTGGCGAGGAGGAGGAGGACGACGACGACGAAGAAGATGAAGACGCTGAGAATGAGGATGAAAATGACAACAATGATGCAGCCACCGATCAGAATCTGCTGCTAACAAGCGACGACGACGATGTGGATGACTTTGACGACGAGCAATCGAAGCATCTGCAGAAACCCTACTGCATATTTTGCAACAAAAAGTTTACGAGCCAATACAAGTTCGAGAATCACATGTTCGTGCATCGAGGCCTGGCCCCCTACCGCTGTGAGCTCTGCACCAATCTCTACAACATGAAGCGACTCCTCATCAGGCACTACAAGACCGTGCACAAGCGCATGCCCACCCGGGACATGGTCCAGGCGAAGGGCGACAAGGTATTGGTGGCCCGCACCAATATCGAGACGATACAACTGGAAATGGATAGGAAGCCCATGCTGATGTGTGCCAAGTGTCCGTTTGAGTGTGAATTGGACACGGAAATGCGAAAGCATCTGAACGCGCATCACGGCATCAACGATGGTGTATCCGTGCATGCCAACGAGGTGTTCATTATACGCAAACTGCCCTTTGAGTGCCCGCGATGCATTCGCTCATTTGCGGCCAAGAGCACACTGACCCGACATCTGCAGCGCAGCCACTTGGTGGACACGATAATTGAGATGCAATCCAACCAAACAACAACCAGCTCGGCAGCGACAACCACAAGCACCACATGCACAGCAACCACCTCAATGCCGGCGAATACGGCTGACGATAATGGGAATAAAGGGCAGCAGCAGCCGCAACAGCAGCAGCAGCTCGAGATGGCTTCGACGGCACCGTCGGGGACGGAGGCTGTTGGCTATGGCGATGGGGAATGCGAGGTAGCAGTTAAACCAGAAGGCGCCGGATTAAAAGAAGAGCCAACAACTACTTCAGCCACATCCGCATCCACATCAGCATCAGCATCATCATCGACATCGATAAGATCGACCATAAAAGCAGAATCGGCTTCAGAAAGAATCCCAAATGCCCCCGACGAATCGTCAGAGCGACGAACCATGAACAGCATAGATCATGTTCTAGTCAAGGGCGAGACAGCATCCGCGCAACATGCCGCCACAACAGCATCATCGTCATCATCCACACCAACGCCATTTGATTTTGACTTTGACTTAATGGGGGATGCAGGAAACTCCAGGCTAACGCCAACGCTAACGCCCACCACGCCCAGTACGAGCAACAAACAAATCGTCAGTACCACACTCCCAGCATACACTAGCAATCCGAGCACGAGCACAAGCACCACCAGCACCAATGCCTTTGCACCCAGCCCCCTACTCAACGGCAGCGACAAACTGTTGACTGCGGCAATGGAGCCATCGCCCATTAAGGGGCTACGTTCGCGCATGCCACGTAACCCCATCTACGTGTGCAAGCTCTGCAAGAAGAGCTTTGATGAGCTGGGCAAGCTGGTAAAGCATGAGATAGAAACGCATTCCATTGGTGAGTCGGCTCGCCTGGGCTATGAGCACAGATGTGGCACCTGTGGGACAACGTATCGCACAATGGCGCTGCTCAAGTTCCACATGAAGCGGCATTTGAACCGCAAGTTTTCGTGCAAGCTGTGCGGAAAGGACTTTGTACACAAAACTGAACTGGACAGACACATGCTGGCCAAACATGTCACCGAGAAGTCGTTCCGATGTTCTCTGGATGGCTGTCGCAAGATGTTCGCCTTTAAGCATCATTTGGTGCGGCATCAGAACGCCTCCCATCTGAAGTTGCGACATGTGTGCTCGATATGCCAGAAAGAGGTGAAGACCAGCCTGCATTTGCGGCACCACATGACCGTACACAGAGGCTTGACAGCCTACAAGTGCCCCAAATGCGACCGCACTTATTTACGTCGCGGAGCACTTCGCGTCCATGCACTGTCCGTCCATCATGTGCAGCTAACGGAGGCAGAGCTGGCGGAAATCTTTCGCCACAATGTGGGCTATACCAATCCACACGACATGAAGGTCATCACACGCAATGGGCAATTGGTGCGGCGCAAGGAGCTGGAGGCCGAACGAGAAAAGGAGATGCAGATGGGCGACGAACCATCCATAGCAGTGGCGAATATATCAAAATAG
Protein Sequence: MASNNRLKTGPGSGSGLSQINYKFTCRCCLKSDAEFLKLDTLAVARNLDPSESDKIPLLRCLLFCIRAENSPELPQYICVECSKSLQIAYYFLQNALRAHEILCRKLCPGKARSTLAHRYNGSIKQPEAALRQPGEDKTKPQKAFRHECKLCGFVVYNRMELKQHIRQHVDGSSYSCKVCSFVTLKQRLLQEHYSATHGMSANQADGRVKPKSTFYSAGPSTSSAAAAVEKEVKVCTLEDMELLIPTVLTPGDYVQPAMDEEQLRDIEQQLAASMGEPVAAGAGALTTNLKQMQCKNMSIGSEYVVMPDGTLQINGGAGVVIEYIDDSRPNSNTTGNLSLQNLLGGDAENEPMDIDVSELIVEEMLPQIKVKPKPIAIGPAPLKYKCKDCPKAFATLGRLKSHQLSHSHLPKFYCDQCPFYSLRSTDLCLHYKTTHLKSDEIRKLAGDESQTYSCDMCLFEGKTSSQLRVHYTEKHMIQPSEVQLRPSWTSESDTVGDGISSARTSGQGSKEQGAQPQHTEIPLGIQYXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTQSGEINVVVDATPLFYAATVAGTDTGAVAAGQGQGQGDPGTIAAEAMANGDTYEIFPEISTSSLTATQPVPALPTPTTSANISMFGDMQDFIDNTDVAAICTIPADDMPVVDGDDIVIDNNNISLDFDAENLFEEFDDEDEAVGEEEEDDDDEEDEDAENEDENDNNDAATDQNLLLTSDDDDVDDFDDEQSKHLQKPYCIFCNKKFTSQYKFENHMFVHRGLAPYRCELCTNLYNMKRLLIRHYKTVHKRMPTRDMVQAKGDKVLVARTNIETIQLEMDRKPMLMCAKCPFECELDTEMRKHLNAHHGINDGVSVHANEVFIIRKLPFECPRCIRSFAAKSTLTRHLQRSHLVDTIIEMQSNQTTTSSAATTTSTTCTATTSMPANTADDNGNKGQQQPQQQQQLEMASTAPSGTEAVGYGDGECEVAVKPEGAGLKEEPTTTSATSASTSASASSSTSIRSTIKAESASERIPNAPDESSERRTMNSIDHVLVKGETASAQHAATTASSSSSTPTPFDFDFDLMGDAGNSRLTPTLTPTTPSTSNKQIVSTTLPAYTSNPSTSTSTTSTNAFAPSPLLNGSDKLLTAAMEPSPIKGLRSRMPRNPIYVCKLCKKSFDELGKLVKHEIETHSIGESARLGYEHRCGTCGTTYRTMALLKFHMKRHLNRKFSCKLCGKDFVHKTELDRHMLAKHVTEKSFRCSLDGCRKMFAFKHHLVRHQNASHLKLRHVCSICQKEVKTSLHLRHHMTVHRGLTAYKCPKCDRTYLRRGALRVHALSVHHVQLTEAELAEIFRHNVGYTNPHDMKVITRNGQLVRRKELEAEREKEMQMGDEPSIAVANISK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00564165; iTF_00603581; iTF_00487533; iTF_00611569; iTF_00515154;
90% Identity: iTF_00564165; iTF_00611569;
80% Identity: -