Basic Information

Gene Symbol
-
Assembly
GCA_900245975.1
Location
NW:12752586-12759576[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 14 0.0076 0.45 10.6 2.6 1 23 147 169 147 169 0.96
2 14 3.6 2.1e+02 2.2 1.0 1 23 175 198 175 198 0.90
3 14 0.00014 0.008 16.1 0.4 1 23 388 410 388 410 0.98
4 14 0.8 47 4.3 1.5 1 23 458 481 458 481 0.91
5 14 0.0037 0.22 11.6 2.1 5 23 791 809 788 809 0.92
6 14 0.042 2.5 8.3 1.4 1 23 815 838 815 838 0.98
7 14 5.8 3.4e+02 1.6 1.3 2 19 878 896 874 898 0.56
8 14 0.00082 0.048 13.7 0.7 1 23 918 941 918 941 0.97
9 14 0.004 0.24 11.5 0.4 1 23 1177 1200 1177 1200 0.92
10 14 0.011 0.63 10.2 3.2 1 23 1212 1234 1212 1234 0.98
11 14 0.0052 0.31 11.1 2.3 1 23 1239 1262 1239 1262 0.94
12 14 0.0018 0.11 12.6 3.8 1 23 1268 1293 1268 1293 0.95
13 14 0.0011 0.062 13.3 4.6 1 23 1298 1320 1298 1320 0.97
14 14 0.00071 0.042 13.9 0.2 1 23 1326 1349 1326 1349 0.96

Sequence Information

Coding Sequence
ATGGCGTTTAACAATAGGCTGAAAACGGGCTCGGGCTCAGCCTCAGGTTTATCCCaaataaactacaaatttACATGTCGCTGCTGTCTGAAATCTGACGCGGAGTTCCTGAAGCTGGACACGATGACGGTGGCGCGCAATCTGGACCCAAGCGAAGCGGATAAAATTCCCCTGCTGCGCTGTTTGTTATTCTGCATACGCGCCGAAAACTCACCGGAGCTGCCGCAATACATATGCGTTGAGTGTAGCAAGAGCCTGCAAATAGCCTACTATTTTCTGCAGAATGCACTGCGCGCACACGAAATACTCTGCCGCAAACTGTGTCCGGGAAAGGTGCGACCCACGTTGGCGCAACGCTTTAACGGTTCCATCAAACAGCCAGAGGTGGCGCCGCGGCAGGCGGCCGAGGACCAGACGAAGCCCCAAAAGGCATTCCGCCACGAGTGCAAACTCTGCGGCTTTGTCGTCTACAATCGGACGGAGCTAAAGGAGCACATTCACCAGCACGTTGATGGCAGCTCATACAGCTGCAAAGTCTGCAGCTTCGTAACGCTGAAGAAGCGTCTACTGCAGGAGCACTACAGTGCGACCCATGGCATGTCGGCCAACCTGGCGGACGAGCGTGTTAAGCCAAAATCTACATCCTACAGTACCGGCCCATCCACTTCAtccgcagcggcggcggctgcgacTGCCAATGAGGAGTTTAAAGTGTGCACGCTGGAGGATATGGAGCTGCTGATTCCCACAGTTCTCACGCCCGGTGACTATGTCCAACCGTCCATCGACGAAGAGCAAGTGCAGGACATTGAACAGGAGCTGGCCGTCAGCATTGGCCAGCCAGTTCCCGTTGCTGCTGAAACGTTAACCAACAATCTGTCCCAGATGCAGGGCAAAAACATGAGCATTGGCTCCGAGTATGTCCTTATGGCCGATGGCAGCATGCAGGTCAACGGAGGCGGTGTGGTGATAGAATACATCGATGATTGCAAGCCAAACCGCAACACCACTGGAAATATGAGCCTTCAAAATCTACTTGGAGGTGGCCCCGAAAACGAGCCCATGGAAATCGACGTCAGTGAGCTGATTGTGGAGGAAATGGTGCCACAGATAAAAGTCAAGCCAAGACCAGTATCCATTGGATCCACTCCCCTCCTCAAGTATAAATGCAAAGCATGTCCCAAAGCATTTGCCACCCTGGGGCGTCTGAAATCTCACCAGTTAAGCCACAGCCATTTGCCCAAGTTCTACTGCGATCAGTGCCCGTTCTACTCGCTGCGCAGCACTGAACTCTGCCTACACTACAAGGCATCGCATCTCAACAAAGAGGAAAAAGGAGGAGCAAAGGAGACCGTCGATGAGTGGCAAACCTATTCCTGCGACATGTGCCTCTTTGAAGGAAGAAACGCCAGGCATCTGCGTGTGCACTACACTGACAAGCATATGATTCAACCCACAGAAGTACAGCTGCGGCCCAGTTGGACAAGTGAGTCGGCCACAGCCGGTGGCGGGATCACTTCGGCTCGTACCAGTGGTCAGGGCTCCAAGGAGCAGGGCGCTCAGCCGCAGCACACCGAAATTCCACTGGGCATTCAATATCCGCCTGCAgctctggcggcggcggcggcggcgacggcAACGGCGACAGTTGGCAATCAGCCAatgcttcagcagcagcagcagcatcaagatcaagagcaacagcaactgtcAGCGATAGCAACACAAACTTCCACGATAACGCAGTCGGGCGAAATCAATGTTGTGGTAGATGCCACACCGTTGTTCTTTGCGGCGACAGCAGCGGGAACtgagactgtgactgtgactggggCAGAGGAACAAGAAGAAGGACAGGGCCAGGCATCTCCGGGCACAATAGCCGCCGATACAATTGCCAACGGGGAGGAGGCCTATGAAATCTTTCCCGAAATCTCAACGAGCAGTCTGACAGCAACACAGCCTGGTCCGGCATTGCCAACGACATCGACAACGTCGGCGAACATCTCAATATTTGGAGATATGCAGGAATTTATAGACAACACAGATGTGGCTGCCATATGCACCATACCCGCCGATGACATGCCCGTGGTGGATGGTGACGATATTGTAATTGATAACAACAATATGAGCCTGGACTTTGATGCTGAGAATCTGTTTGAGGACTTTGAGGATGAGGAAGAGGCCGttggcgaggaggaggaggacgaggaggaggatgacgacgacgacgaggacgctgagaatgaagatgaaaatgaCAACAATGATGCGGCCACCGATCAGAATCTGCTGCTAAcaagcgacgacgacgatgtcgATGACTTTGACGACGAGCAATCAAAGCATCTGCAGAAACCCTACTGCatattttgcaacaaaaagtttaCCAGCCAATACAAATTCGAGAATCACATGTTTGTGCATCGAGGCCTGGCCCCCTATCGCTGTGAGCTCTGCACGAATCTCTACAACATGAAGCGTCTCCTCATCCGGCACTACAAGACCGTGCACAAGCGCATGCCCACGCGTGACATGGTCCAGGCGAAGGGCGACAAGGTATTGGTGGCACGTACCAATATCGAGACGATACAACTGGATACGGATAGGAAGCCGATGCTGATGTGTGCGAAGTGTCCGTTTGAATGTGAATTGGATACGGAAATGCGAAAGCATTTGAATGCGCATCATGGCATCAATGATGGTGTATCCCTGCATGCCAACGAGGTGTTCATTATACGCAAACTACCATTTGAGTGCCCGCGATGCATTCGGTCATTTGCTGCCAAGAGCACACTGACACGCCATCTGCAGCGTAGCCATTTGGTGGACACTATAATTGAGATGCAATCGAATCAAACAACCAGCagctcagcagcaacaaccacaagcaCCACATGCACGGCAACAACTTCAATGCCGGCGAACACGGCTGACGATAATGGGAAtaaggggcagcagcaggggacGGAGACTGTTGGctatggcgatggcgatgtcgTTGGCGATGGCGTTGGGGAATGCGAGGTAGAAGTCAAACCTGAAGAAGGCGCCGGAATAAAAGAAGAGCCGACTTCAGCCGCATCAGCATCGGCATCGATAAGAACAGCCATAAAAGCAGAATCAGCTTCAGAAATAATTCCAAATCCCCCCGACGAATCGCCAGAGCCACGAATCATGAACAGCATTGATCATGTTCTAGTCAAGGGCGAGACATCATCTGTGCCACACATCGCCACCACAACAGCATCATCGTCATCCACACCAACCCCATTtgattttgactttgactttatAGGGGATGCAGGAAAATCCAGACTTACGCCTACTTTTACGCCCACCCCGCCCAGTACTAGCAACAGTCAAATTGTCAGCACCACACCACTCCCATGCACGAGCAcaagcaccaccagcaccgaCGCCTGTTCACCCAGTCCCCTACTCAACGGCAGCGACAAACTGTTGACTGCCGCAATGGAGCCATCGCCCTTCAAGGGGCTAAGGTCGCGCACGCCACGCACCCAAATCTACGCGTGCAAGCTCTGCAAAAAGAGCTTCGATGAACTGGGAAAGCTGGTGAAGCATGAGATGGATACACATTCCATTGGCGAATCGAAACGATCGGGCTACGAGCACAGATGTGGCACCTGTGGAACAACGTATCGCACAATGGCGCTGCTCAAGTTCCACATGAAGCGCCACGCGAATCGCAAGTTTTCGTGCAAGTTTTGTGAAAAGGATTTTgtacacaaaacagaaatggaCAGGCATATTCTGGCCAAACATGCCACCGAGAAGTCGTTTCGATGTTCGCTGGATGGCTGTCGCAAGATGTTCGCCTTTAAGCATCATTTGGTGCGGCATCAGAATGCCTCGCATCTGAAGTTGCGACATGTGTGCGCGATATGTCAGAAAGAGGTGAAGACCAGCCAGCATCTGCGGCACCACATGACCGTTCACAGAGGCATGACAGCCTACAAGTGCCCCAAATGCGACCGCACATATTTACGTCGCGGAGCCCTTCGCGTCCATGCACTGTCGGTGCATAAGGTGCGGCTCACGGAGGATGAGCTGGCGGAAATCTTTCGCCACAATGTGGGCTACACCAATCCACACGACATGAAGGTCATCGCACGCAATGGGCAACTGGTGCGCCGcaaggagctggaggtggaACGAGAAAATGAGTTGCAGCTGGGCGACGAACCATCCCAAGCAGAGGCGAATATTTCATAA
Protein Sequence
MAFNNRLKTGSGSASGLSQINYKFTCRCCLKSDAEFLKLDTMTVARNLDPSEADKIPLLRCLLFCIRAENSPELPQYICVECSKSLQIAYYFLQNALRAHEILCRKLCPGKVRPTLAQRFNGSIKQPEVAPRQAAEDQTKPQKAFRHECKLCGFVVYNRTELKEHIHQHVDGSSYSCKVCSFVTLKKRLLQEHYSATHGMSANLADERVKPKSTSYSTGPSTSSAAAAAATANEEFKVCTLEDMELLIPTVLTPGDYVQPSIDEEQVQDIEQELAVSIGQPVPVAAETLTNNLSQMQGKNMSIGSEYVLMADGSMQVNGGGVVIEYIDDCKPNRNTTGNMSLQNLLGGGPENEPMEIDVSELIVEEMVPQIKVKPRPVSIGSTPLLKYKCKACPKAFATLGRLKSHQLSHSHLPKFYCDQCPFYSLRSTELCLHYKASHLNKEEKGGAKETVDEWQTYSCDMCLFEGRNARHLRVHYTDKHMIQPTEVQLRPSWTSESATAGGGITSARTSGQGSKEQGAQPQHTEIPLGIQYPPAALAAAAAATATATVGNQPMLQQQQQHQDQEQQQLSAIATQTSTITQSGEINVVVDATPLFFAATAAGTETVTVTGAEEQEEGQGQASPGTIAADTIANGEEAYEIFPEISTSSLTATQPGPALPTTSTTSANISIFGDMQEFIDNTDVAAICTIPADDMPVVDGDDIVIDNNNMSLDFDAENLFEDFEDEEEAVGEEEEDEEEDDDDDEDAENEDENDNNDAATDQNLLLTSDDDDVDDFDDEQSKHLQKPYCIFCNKKFTSQYKFENHMFVHRGLAPYRCELCTNLYNMKRLLIRHYKTVHKRMPTRDMVQAKGDKVLVARTNIETIQLDTDRKPMLMCAKCPFECELDTEMRKHLNAHHGINDGVSLHANEVFIIRKLPFECPRCIRSFAAKSTLTRHLQRSHLVDTIIEMQSNQTTSSSAATTTSTTCTATTSMPANTADDNGNKGQQQGTETVGYGDGDVVGDGVGECEVEVKPEEGAGIKEEPTSAASASASIRTAIKAESASEIIPNPPDESPEPRIMNSIDHVLVKGETSSVPHIATTTASSSSTPTPFDFDFDFIGDAGKSRLTPTFTPTPPSTSNSQIVSTTPLPCTSTSTTSTDACSPSPLLNGSDKLLTAAMEPSPFKGLRSRTPRTQIYACKLCKKSFDELGKLVKHEMDTHSIGESKRSGYEHRCGTCGTTYRTMALLKFHMKRHANRKFSCKFCEKDFVHKTEMDRHILAKHATEKSFRCSLDGCRKMFAFKHHLVRHQNASHLKLRHVCAICQKEVKTSQHLRHHMTVHRGMTAYKCPKCDRTYLRRGALRVHALSVHKVRLTEDELAEIFRHNVGYTNPHDMKVIARNGQLVRRKELEVERENELQLGDEPSQAEANIS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00474725;
90% Identity
-
80% Identity
-