Basic Information

Insect: Drosophila obscura
Gene Symbol: -
Assembly: GCA_018151105.1
Location: NW:1140206-1147347[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.00064 0.039 14.1 1.5 1 23 145 167 145 167 0.97

2 14 3.7 2.3e+02 2.3 0.8 1 23 173 196 173 196 0.89

3 14 1.7e-05 0.001 19.1 1.1 1 23 383 405 383 405 0.98

4 14 0.11 6.5 7.1 0.7 1 23 451 474 451 474 0.93

5 14 0.004 0.24 11.6 2.1 5 23 778 796 775 796 0.92

6 14 0.046 2.8 8.3 1.4 1 23 802 825 802 825 0.98

7 14 6.3 3.8e+02 1.6 1.3 2 19 865 883 861 885 0.56

8 14 0.00089 0.054 13.7 0.7 1 23 905 928 905 928 0.97

9 14 0.0024 0.15 12.3 0.4 1 23 1182 1205 1182 1205 0.91

10 14 0.012 0.7 10.2 3.2 1 23 1217 1239 1217 1239 0.98

11 14 2.8e-05 0.0017 18.4 1.7 1 23 1244 1267 1244 1267 0.95

12 14 0.0019 0.12 12.6 3.8 1 23 1273 1298 1273 1298 0.95

13 14 0.0024 0.15 12.3 5.1 1 23 1303 1325 1303 1325 0.97

14 14 0.001 0.061 13.5 0.8 1 23 1331 1354 1331 1355 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.00064	0.039	14.1	1.5	1	23	145	167	145	167	0.97
2	14	3.7	2.3e+02	2.3	0.8	1	23	173	196	173	196	0.89
3	14	1.7e-05	0.001	19.1	1.1	1	23	383	405	383	405	0.98
4	14	0.11	6.5	7.1	0.7	1	23	451	474	451	474	0.93
5	14	0.004	0.24	11.6	2.1	5	23	778	796	775	796	0.92
6	14	0.046	2.8	8.3	1.4	1	23	802	825	802	825	0.98
7	14	6.3	3.8e+02	1.6	1.3	2	19	865	883	861	885	0.56
8	14	0.00089	0.054	13.7	0.7	1	23	905	928	905	928	0.97
9	14	0.0024	0.15	12.3	0.4	1	23	1182	1205	1182	1205	0.91
10	14	0.012	0.7	10.2	3.2	1	23	1217	1239	1217	1239	0.98
11	14	2.8e-05	0.0017	18.4	1.7	1	23	1244	1267	1244	1267	0.95
12	14	0.0019	0.12	12.6	3.8	1	23	1273	1298	1273	1298	0.95
13	14	0.0024	0.15	12.3	5.1	1	23	1303	1325	1303	1325	0.97
14	14	0.001	0.061	13.5	0.8	1	23	1331	1354	1331	1355	0.95

Sequence Information

Coding Sequence: ATGGCATCTAACAATAGGTTGAAAACGGGCTCAGGCTCAGGATTATCCCaaataaactacaaatttacaTGTCGCTGCTGTCTGAAATCCGATGCGGAGTTCCTCAAACTGGACACGCTGGCGGTGGCGCGCAATCTAGATCCAAGTGAAGCGGATAAAATTCCCCTGCTGCGTTGTCTGCTATTCTGCATACGCGCCGAAAACTCGCCGGAGCTGCCACAATACATATGCGTTGAGTGTAGCAAGAGCTTGCAAATAGCCTACTACTTCCTGCAGAATGCACTGCGCGCACACGAAATACTCTGCCGCAAACTGTGTCCGGGAAAGGCCCGTCCCACGCTGGCGCAGCGCTACAACGGGTCCATCAAACAGCCagagGCGGCGCTGCGGCAGACGGGGGAGGACAAGACGAAGCCCCAAAAGGCATTCCGGCACGAGTGCAAACTCTGCGGCTTTGTCGTCTACAATCGGATGGAGCTAAAGCAGCACATACGGCAGCACGTTGATGGCAGCTCCTACAGCTGCAAAGTCTGCAGCTTCGTTACGCTAAAGCAGCGTCTCTTGCAGGAGCACTATAGTGCGACCCATGGCATGTCGGCCAACCAGGCGGACGATCAAGTGAAACCAAAATCTACATTCTACAGTGCCACCCCCTCCACTTCAtccgcggctgctgctgtcgagAAGGAGGTTAAAGTGTGCACCCTGGAGGACATGGAGCTGCTGATTCCCACAGTTCTCACGCCTGGTGACTATGTCCAACCGTCCATCGACGAAGATCAACTGCGCGACATTGAACAGCAGCTGGCCGCCAGCATGGGCGAGCCtgtggctgctggtgctggcgctTTGACCACCAATCTGACTCAAATGCAGTGCAAAAATATGAGCATTGGCAGCGAATATGTCGTCATGCCCGATGGGACCTTGCAGATAAACGGAGGCGCAGGTGTGGTGATAGAATACATCGATGATAGCAGgcccaacagcaacaccacTGGAAATTTGAGCCTTCAAAATCTTCTTGGAGGTGGTGCCGAAAACGAGCCCATGGACATCGATGTCAGTGAACTAATTGTGGAGGAAATGCTGCCGAAGATAAAAGTCAAGCCAAAACCAATACCCATTGGATCCGCTCCCCTCAAGTACAAGTGCAAAGACTGTACCAAAGCATTTGCCACCCTGGGGCGTCTGAAATCTCACCAGTTGAGCCACAGCCATTTGCCCAAGTTCTACTGCGATCAGTGCCCCTTCTACTCGCTGCGCAGTACCGATCTCTCTCTGCACTACAAGGCAACGCATCTCAGGAACGAGAGGAATGGAAAGGAGGCCGGCGATGAATCGCAAACTTATTCCTGCGACATGTGCCTCTTCGAAGGGAGGACCTCCAGCCAGCTGCGGGTGCACTACACTGAGAAGCATATGATTCAACCGTCGGAGGTACAGCTGCGTCCCAGTTGGACAAGTGAGTCAGACACCGTCGGTGACGGCATCAGTTCGGCTCGCACCAGTGGCCAAGGCTCCAAGGAGCAGGGCGCTCAGCCGCAGCACACCGAAATTCCACTGGGCATTCAATATCCGCCTGCAgcgctggcggcggcggcgacggtTGACAATCAGCCAATgcttcagcatcagcaacaacagcaacaggatcagcagcaacagcagcagcagcagccggagcaACTGTCAGCGATAGCAACCCAAACATCCACGATAACGCAGTCGGGCGAAATCAATGTGGTGGTAGATGCCACACCGTTGTTCTATGCGGCGACAGTAGcagggactggcactgggacagTGGTAGAGGGAcaaggacagggacagggaaaTCCGGGTACAATAGCCGCTGAGGCAATGGCCAACGGGGACACATATGAAATCTTTCCAGAAATCTCAACGAGCAGTCTGACAGCGACACAGCCCGTACAGGCATTGCCAACGCCGACAACGTCGGCGAACATCTCCATGTTTGGGGATATGCAGGATTTTATTGACAACACAGATGTGGCCGCCATATGCACCATACCCGCCGATGATATGCCCGTGGTGGATGGTGACGATATTGTGATTGACAACAACAATATCAGCTTAGACTTTGATGCTGAGAATCTGTTTGAGGAGTTTGATGATGAGGACGAGGCCGTTggcgaggatgaggaggaggacgaagaCGACGAAGAAGATGAAGACGCTGAGAATGAGGATGAAAATGACAACAATGATGCAGCCACCGATCAGAATCTGCTGCTAAcaagcgacgacgacgatgtgGATGACTTTGACGACGAGCAATCCAAGCATCTGCAAAAACCCTACTGCATATTTTGCAACAAAAAGTTTACAAGCCAATACAAGTTCGAGAATCACATGTTTGTGCATCGAGGCCTGGCCCCCTACCGCTGTGAGCTCTGCACCAATCTCTACAACATGAAGCGTCTCCTCATCAGGCACTACAAGACCGTGCACAAGCGCATGCCCACCCGGGACATGGTCCAGGCGAAGGGCGACAAGGTATTGGTGGCCCGCACCAATATCGAGACAATACAACTGGAAATGGATAGGAAGCCCATGCTGATGTGTGCCAAGTGTCCGTTTGAGTGTGAATTGGACACGGAAATGCGAAAGCATCTGAATGCGCATCACGGCATCAACGATGGAGTATCCGTGCATGCCAACGAGGTCTTCATTATACGCAAACTACCCTTTGAGTGCCCGCGATGCATTCGCTCCTTTGCGGCTAAGAGCACACTGACCCGACATCTGCAGCGCAGCCATTTGGTGGACACGATAATTGAGATGCAATCCAACCAAACAACAAGCAGCTCGGCAGCGACAACCACAAGCACCACATGCACAGCAACCACCTCAATGCCGGCGAATACGGCTGACGATAATGGGAATaaagggcagcagcagctcgagaTGGCTTCGACGGCACCGTCGGGGACGGAGACTGTTGGCTATGGCGATGGGGAATGCGAGGTAGCAGTCAAACCAGAAGGCGCCGGATTAAAAGAAGAGCCAACAACTACTTCAGccacatccgcatccacatcagcatcagcatcatcatcatcgacaTCGATAAGATCGACCATAAAAGCAGAATCAGCTTCAGAAAGAACCCCAAATCCCCCCGACGAATCGTCAGAGCCACGAACCATGAACAGCATAGATCATGTTCTAGTCAAGGGCGAGACAGCATCCGCGCAACATACCGCCACAACAgcatcgtcgtcatcatccACACCAACGCCATTtgattttgactttgacttaATGGGGGATGCAGGAAACTCCAGGCTTACGCCAACGCTTACGCCCACCACGCCCAGTACGAGCAACAAACAAATCGTCAGTACCGCACTCCCAGCATACACTAGCAATCCGAGCACGAGCACAAGCACCACCAGCCCAAGCACCAATGCATTTGCACCCAGCCCCCTACTCAACGGCAGCGACAAACTGTTGACTGCGGCAATGGAGCCATCGCCCATTAAGGGGCTACGTTCGCGCATGCCACGTAACCCCATCTACGTGTGCAAGCTCTGCAAGAAGAGCTTTGATGAGCTGGGCAAGCTGGTAAAGCATGAGATAGAAACGCATTCCATTGGTGAATCGGCACGCTTGGGCTATGAGCACAGATGTGGCACCTGTGGGACAACGTATCGCACAATGGCGCTACTCAAGTTCCACATGAAGCGGCATTTGAACCGCAAGTTTTCGTGCAAGCTGTGCGGAAAGGACTTTGTACACAAAACTGAACTGGACAGACACATGCTGGCGAAACATGCCACCGAGAAGTCGTTCCGATGTTCTCTGGATGGCTGTCGCAAGATGTTCGCCTTCAAGCATCATTTGGTGCGGCATCAGAACGCCTCCCATCTGAAGTTGCGCCATGTGTGCTCGATATGCCAGAAAGAGGTGAAGACCAGCCTGCATTTGCGGCACCACATGACCGTACACAGAGGCTTGACAGCCTACAAGTGCCCCAAATGCGACCGCACTTATTTACGTCGCGGAGCACTTCGCGTCCATGCACTGTCCGTTCATCATGTGCAGCTAACGGAATCAGAGCTGGCGGAAATCTTTCGCCACAATGTGGGCTATACCAATCCACACGACATGAAGGTCGTCACACGCAATGGGCAATTGGTGCGGCGCAAGGAGCTGGAGGCCGAACGAGAAAAGGAGATGCAGATGGGCGACGAACCATCCGTAGCAGTGGCGAATATATCAAAATAG
Protein Sequence: MASNNRLKTGSGSGLSQINYKFTCRCCLKSDAEFLKLDTLAVARNLDPSEADKIPLLRCLLFCIRAENSPELPQYICVECSKSLQIAYYFLQNALRAHEILCRKLCPGKARPTLAQRYNGSIKQPEAALRQTGEDKTKPQKAFRHECKLCGFVVYNRMELKQHIRQHVDGSSYSCKVCSFVTLKQRLLQEHYSATHGMSANQADDQVKPKSTFYSATPSTSSAAAAVEKEVKVCTLEDMELLIPTVLTPGDYVQPSIDEDQLRDIEQQLAASMGEPVAAGAGALTTNLTQMQCKNMSIGSEYVVMPDGTLQINGGAGVVIEYIDDSRPNSNTTGNLSLQNLLGGGAENEPMDIDVSELIVEEMLPKIKVKPKPIPIGSAPLKYKCKDCTKAFATLGRLKSHQLSHSHLPKFYCDQCPFYSLRSTDLSLHYKATHLRNERNGKEAGDESQTYSCDMCLFEGRTSSQLRVHYTEKHMIQPSEVQLRPSWTSESDTVGDGISSARTSGQGSKEQGAQPQHTEIPLGIQYPPAALAAAATVDNQPMLQHQQQQQQDQQQQQQQQPEQLSAIATQTSTITQSGEINVVVDATPLFYAATVAGTGTGTVVEGQGQGQGNPGTIAAEAMANGDTYEIFPEISTSSLTATQPVQALPTPTTSANISMFGDMQDFIDNTDVAAICTIPADDMPVVDGDDIVIDNNNISLDFDAENLFEEFDDEDEAVGEDEEEDEDDEEDEDAENEDENDNNDAATDQNLLLTSDDDDVDDFDDEQSKHLQKPYCIFCNKKFTSQYKFENHMFVHRGLAPYRCELCTNLYNMKRLLIRHYKTVHKRMPTRDMVQAKGDKVLVARTNIETIQLEMDRKPMLMCAKCPFECELDTEMRKHLNAHHGINDGVSVHANEVFIIRKLPFECPRCIRSFAAKSTLTRHLQRSHLVDTIIEMQSNQTTSSSAATTTSTTCTATTSMPANTADDNGNKGQQQLEMASTAPSGTETVGYGDGECEVAVKPEGAGLKEEPTTTSATSASTSASASSSSTSIRSTIKAESASERTPNPPDESSEPRTMNSIDHVLVKGETASAQHTATTASSSSSTPTPFDFDFDLMGDAGNSRLTPTLTPTTPSTSNKQIVSTALPAYTSNPSTSTSTTSPSTNAFAPSPLLNGSDKLLTAAMEPSPIKGLRSRMPRNPIYVCKLCKKSFDELGKLVKHEIETHSIGESARLGYEHRCGTCGTTYRTMALLKFHMKRHLNRKFSCKLCGKDFVHKTELDRHMLAKHATEKSFRCSLDGCRKMFAFKHHLVRHQNASHLKLRHVCSICQKEVKTSLHLRHHMTVHRGLTAYKCPKCDRTYLRRGALRVHALSVHHVQLTESELAEIFRHNVGYTNPHDMKVVTRNGQLVRRKELEAEREKEMQMGDEPSVAVANISK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00474725;
90% Identity: iTF_00474725;
80% Identity: -