Basic Information

Gene Symbol
-
Assembly
GCA_029229535.1
Location
CM055252.1:12921481-12935228[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 21 0.00032 0.029 15.3 1.0 2 23 235 257 235 257 0.97
2 21 0.008 0.73 10.9 1.3 1 21 361 381 361 382 0.95
3 21 0.046 4.2 8.5 5.7 1 23 411 434 411 434 0.92
4 21 3.5 3.2e+02 2.6 0.0 6 20 445 459 445 461 0.94
5 21 0.027 2.4 9.3 0.3 1 22 467 488 467 490 0.90
6 21 0.00011 0.0097 16.8 0.8 2 23 565 586 565 586 0.97
7 21 0.58 53 5.0 0.2 1 16 629 643 629 651 0.72
8 21 0.0028 0.26 12.3 0.4 2 23 655 676 654 676 0.96
9 21 0.00069 0.063 14.3 0.2 3 21 711 729 711 733 0.92
10 21 0.00075 0.069 14.1 0.5 1 23 755 778 755 778 0.98
11 21 0.0037 0.34 11.9 2.4 2 23 792 813 791 813 0.97
12 21 0.0025 0.23 12.5 8.3 1 21 842 862 842 864 0.94
13 21 0.0019 0.18 12.8 0.2 2 23 880 902 880 902 0.93
14 21 0.00021 0.019 15.9 0.8 1 23 918 940 918 940 0.97
15 21 0.00026 0.024 15.6 0.9 2 23 952 974 951 974 0.95
16 21 3.4e-05 0.0031 18.4 0.3 1 23 989 1011 989 1011 0.95
17 21 1.6 1.5e+02 3.6 0.0 1 23 1056 1079 1056 1079 0.94
18 21 0.00014 0.012 16.5 2.1 2 23 1090 1111 1090 1111 0.97
19 21 2.7e-05 0.0025 18.7 0.9 1 23 1145 1168 1145 1168 0.97
20 21 5.4e-06 0.00049 20.9 1.1 1 23 1176 1198 1176 1198 0.98
21 21 0.00072 0.066 14.2 0.1 1 23 1213 1236 1213 1236 0.97

Sequence Information

Coding Sequence
ATGGCAGAAGGAGAAATTGTCGATTTCCAATCATGTTGTAGACTGTGTCTCACCGAAATTGTGGAAAGTATTAAGTCAATATTCGATGAGACTGTCGAAGATAGAAGATTATCCGAAAAGATACAGCAATCAGTTGCTATTGAGATAAACTGTTCTGATAAATTATCCACAAAAGTATGTGATCCCTGTATAGAAAAAGTAGTGGGTTGGTACTCCTTCAAAGAGCAATGTCTAAAGAATCAAAAGAAGCTAGAAGATTGGATAAATTCCAAAAATCCAGATGGTTCAAGCGAGTTAACACCTGAACAAACATCAACACCCCAATCAGAAGTAACACCTGAAGTAAACTCCTCACATAGCTCCACATCTATATCAAATGTGGCTATACAGATAAAAGAAGAACCACAAGATCACATAGAAGAACCACAAGTTGATGACCACCAGGAAGATATTTTTAACAATCTTTCAGATACTGTTGATTCGCAACTAGACCAACAGAATGACATCCACAACGATATTCAACCAGAGCTTATGCACCATAACCATGTACTAGTAAAATCAGAACCGTTAGATATGGATGGTTTGGAAGAACCCATGGAAGAAGAGTACAACGAATTTCCTCCAAATTTGTCTCCACAGCATTTagaaaatggtgaaaatttaCAAGAACCTTTAGTTGTCAGGACTACCGCTTTCAATAGAACATGTAGCGTTTGCGGCAAATTATTTAGTAATgcaggaaacaaaaaaaagcatGAAAGGATGCAGCATGGTCTTCACAATAACATTTCTATTGCTACTCCAATACTTAACGGTCTTACTAATGGCGACGTCCAACACGGCTCGCCGATTCAAACCGAACAACAAAAAATCTTAAATTCCATGAGCCTCAAAGTTTTGAAAACAATTCCAATAGAAACACcagaaaatttaacaaaaatagaaaatagttaCGTGGAAAAATGCAAGGCGATGGTCAGTATGCACAAAACATTAATTTGTGCCTGCCACAATGTTCCTCATCAGAATCTTAAAGGATTATTATCACATCTGCGAGCTTTGAGGATCTGGTTTCCTGTTTTTACATGTTATAATTGCATGATAACGTTCACGGATAGATCCACGTTCACCAGACATATTTCAAgATGTCAGAGCGCTCCATTGGACACTATTACCAAACTGAGTGAGCTTAGAATACGCACCGAAGTTAAAACTAGACTTTACCAAAACTTTAAATGCACCATCTGCAAATTTATGTTCAGTTTTCACGAAGATTTTTGTAAACACGTCGACGAAGATCATGCCATGCTACAATTCCCAGTGCATTGTCCTTGCGGTAAAACTTGCGAAAACGAAGAAGAATATAAGGATCATGTTTACGTTAGTTGTCTAGTCGAATTTTATTGTGACATATGCTTCGTTACTACTAAAACACTAGATGATTTCCAGAAACATGCTGCAGGAGTTCACGATGACTCCGAAGGATTTATACTTCTCCAGGATGATAATTATAAAGTTAGAAAACCTTCTATGCACGTCAGCCCTACAGGAGTAGATGAAGGGGCTATTATACAAGGTAAACGAGAGCGAAAGGCCTCTTTCAAAACGCCACTGTACGATGACGATTTAGACGAAATATTACCCACAAGTCTTGCATCTGCAACTTACTATACCCCTAAAACGACTAATAGAGTCTGTCCTATTTGCTACAAAGAATATTCGTCTTACAAAAACATGATGCGCCATTATAAAACCCACAAACCTGAAGAAATCCAAAACCATCAACAACAGCAACAAATGGAACAAGGTTATTCCGAATTTCAAGATTATCAAGATCAATCGCAAGAATCTCAAGATATGGAATTGGAAGAGGAAGAATCTTTCTATTCTTGTCCTGATTGTGGAGGCATGTACAGCACTATGGAATGGAAAGTGCATTTGACTGAAAAACATCCATCGAAACCTTGCGGGGAATGTGGGAAATTCTTCCAATTCCAAACCGAGCTTGATCAACACAGAAGCGTTCATCTGAATCTTAAGgtATACAGAGATTCCAAAACCCAGTCTTACAAGAGTACGATGCTCAGTCCAGGAGGAGAAGGTGAAGGGGAAGGAGAAGAGATGGTTGGTTGCGAAATGTGCGATTTGGTGTTCACATCCAAAGAAGATCTGATGACTCATCAATTAGAACAAGGACACGCCGGTATTACCGCCGTGGAGGTACCGGAACCCGAACCAGAAGTTACTGCAGCTCCAAAGAAATATAGATGCGACATTTGCGAACaagaatttaataattacaaCGGTTTATGGGAACATAATAGAACTAGACATCCGGAAAGGAAAACTCCTCACGCGGATACGTATCCGAAACAATGCAAAGATTGCAATAAAGTGTGTACAACCGGAGCTGCATATTACAGACATAGACAGATACACGAAAAAGTACCAGCCGACGCTGCGGCTAGCAAAGCTACCTTATTGAAACCAAAGAAGTTCGAAGAACCCGAAGAAGAATCTTATCACACTTGCAAACGTTGTTTCAAAGTGTTTTCCAGCAAATATAATCTCAAGAACCATCTGAAATGTCACGGAATTAACATAAATCCAATCAGTAAGAAATTGGTAAGAAAAGCGGTCTGTAAAGTATGTCAGAACGTTTTTGAAACTAACGAAGAACTTATCAGACATAAACAAGAAGCCCACAACGGCGTTGAAACCCCCGACGATATGGATATGGCCTCATTAGTGTTCCCTTGTGACACTTGCGTTATGACATTCACTAGCAAAGCCGCTTTGaaaaaacacaaagaaaaacATACTTTAGAATATAAATCACTACACAGACAAGTGTACTGTAAATACTGCAAGATTTCGTTTGAGAATTTCCAAAGTTTGACTCAACATATGCAGTTAGAACACAACGAGAAAGTCAAAATGCCACCAATACCTAAGCCAAATGACTTCACTTGTTCTATTTGTCAAAAATCATTCCAATCTTCAGGCGCTTTAACGACACACATCGGTTGGCATAAAAGGGCTCTAAATGACAGCAGTTCTAAATTATTGAAACACGCTCCTCCTAGCCTTCCACCGCCGCCAGTACAGCTACCGCGAATGCATCAAGTAAACATTAAAGAAGAACCAATGGACGACGTAACCAAGTACCAATGCGATACTTGTTTGGCCGAATTACCCAACGATACCGCTCTGCAAGTACACATTCTGGAAAAACACAGAAGCGTCAGCGCAATTATGCTAATTCCACGTTGTAACACTTGCAACAAAGATTTTTCTACACAAGACGAATACGAAACGCACAAAAGATTGCACGATTTCTTGGAACGTCAAAAACAACACGAACAAAAAATGTTGGTGCAACAACAAGAAATGCCTTCGCAGAGAATGTCGCCGGCTAATAAACAAAAGAGTTTCCCTTGTAAACATTGTAACGCAGCTTTCAGCAGGTCTGACACGCTAGGAGCTCACATTAGACAGTTCCATAAGGAGCACGTTCAGACAGAATTCAAATGTAATCAATGCGACAgagttttcgaaaaacaaaactCTCTTACAATACACTTGAAAGTTCACGAGAAACAGAGAGCCGTACCATCTCCGGTCGGTAAACCGCTCTTCTCTTGCTCTATCTGTAACATGGGTTTCGATTTACCAAAGGATTTGCGAGCTCATACTATTACGGCTCATCCATTTTGA
Protein Sequence
MAEGEIVDFQSCCRLCLTEIVESIKSIFDETVEDRRLSEKIQQSVAIEINCSDKLSTKVCDPCIEKVVGWYSFKEQCLKNQKKLEDWINSKNPDGSSELTPEQTSTPQSEVTPEVNSSHSSTSISNVAIQIKEEPQDHIEEPQVDDHQEDIFNNLSDTVDSQLDQQNDIHNDIQPELMHHNHVLVKSEPLDMDGLEEPMEEEYNEFPPNLSPQHLENGENLQEPLVVRTTAFNRTCSVCGKLFSNAGNKKKHERMQHGLHNNISIATPILNGLTNGDVQHGSPIQTEQQKILNSMSLKVLKTIPIETPENLTKIENSYVEKCKAMVSMHKTLICACHNVPHQNLKGLLSHLRALRIWFPVFTCYNCMITFTDRSTFTRHISRCQSAPLDTITKLSELRIRTEVKTRLYQNFKCTICKFMFSFHEDFCKHVDEDHAMLQFPVHCPCGKTCENEEEYKDHVYVSCLVEFYCDICFVTTKTLDDFQKHAAGVHDDSEGFILLQDDNYKVRKPSMHVSPTGVDEGAIIQGKRERKASFKTPLYDDDLDEILPTSLASATYYTPKTTNRVCPICYKEYSSYKNMMRHYKTHKPEEIQNHQQQQQMEQGYSEFQDYQDQSQESQDMELEEEESFYSCPDCGGMYSTMEWKVHLTEKHPSKPCGECGKFFQFQTELDQHRSVHLNLKVYRDSKTQSYKSTMLSPGGEGEGEGEEMVGCEMCDLVFTSKEDLMTHQLEQGHAGITAVEVPEPEPEVTAAPKKYRCDICEQEFNNYNGLWEHNRTRHPERKTPHADTYPKQCKDCNKVCTTGAAYYRHRQIHEKVPADAAASKATLLKPKKFEEPEEESYHTCKRCFKVFSSKYNLKNHLKCHGININPISKKLVRKAVCKVCQNVFETNEELIRHKQEAHNGVETPDDMDMASLVFPCDTCVMTFTSKAALKKHKEKHTLEYKSLHRQVYCKYCKISFENFQSLTQHMQLEHNEKVKMPPIPKPNDFTCSICQKSFQSSGALTTHIGWHKRALNDSSSKLLKHAPPSLPPPPVQLPRMHQVNIKEEPMDDVTKYQCDTCLAELPNDTALQVHILEKHRSVSAIMLIPRCNTCNKDFSTQDEYETHKRLHDFLERQKQHEQKMLVQQQEMPSQRMSPANKQKSFPCKHCNAAFSRSDTLGAHIRQFHKEHVQTEFKCNQCDRVFEKQNSLTIHLKVHEKQRAVPSPVGKPLFSCSICNMGFDLPKDLRAHTITAHPF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

90% Identity
-
80% Identity
-