Basic Information

Gene Symbol
-
Assembly
GCA_963924685.1
Location
OZ004725.1:12983848-12989100[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.0015 0.12 13.6 0.5 1 23 341 364 341 364 0.95
2 12 2.5e-06 0.0002 22.3 1.1 1 23 369 392 369 392 0.97
3 12 8.7e-05 0.007 17.5 4.4 1 23 397 419 397 419 0.97
4 12 0.0002 0.016 16.4 2.8 2 23 426 447 425 447 0.97
5 12 0.0016 0.13 13.5 2.8 2 23 455 477 455 477 0.95
6 12 0.016 1.3 10.4 1.2 1 23 483 506 483 506 0.95
7 12 0.0033 0.27 12.5 0.9 2 23 517 539 516 539 0.94
8 12 9.8e-07 7.9e-05 23.6 0.6 1 23 567 589 567 589 0.98
9 12 7e-06 0.00056 20.9 2.3 1 23 596 618 596 618 0.96
10 12 0.00024 0.019 16.1 0.2 3 23 626 646 625 646 0.97
11 12 0.011 0.92 10.8 1.2 1 23 653 675 653 675 0.98
12 12 0.0012 0.098 13.9 3.3 1 23 681 704 681 704 0.98

Sequence Information

Coding Sequence
atggaAACTTGTCGTACGTGTGCCAAATGTGATTTTGATAATGAAAGCCAAtggtttgatttatttaatgcCCCCCGTTGGCAAATTGAAATGCAACGCATACATTTGGAGTTAAATGCCTGGAAAATAAAGATATCCTGTAACGATGGCCTGCCACAAAAAATTTGCCCCGattgcttttcaaaattttgcacaGTCTCCTCTTTTCGTGAGCAATGTTTGGAGGCACAAACAAGTTTAAGCAATATATTCGATAAAATCGATACACAATGTATACAAGGGGAAGAAGAACAAGAAGTTTTTGAGGGTTTTCCTAATGAACAGGATAATAATGCACAAAGTACCGTAACAACTGTAATACATTCTGCGACAGCGGTTGTAGCCACAGCGACCGCAGCAGCAAAAACAATTGAGCACACATTTGAGACAACAGAAAAGAGCAACATTAGCAGCAATAGTGGCTGcaatagcaataataataatgAAAGTATAATAAGttttagtgaaattttaaatttaaatcgtaAAAACAACACCGATACTTCAgttcgaaatattgaaaaattaccaGACACTGcccttttaaaaaataagattaaaaattttaatcatataTTTGAAGAATTAGAAGATATTGAAAATAACCCTGTTGATCATGATGTTGAGGATGCCTGTTCGAAGACTATAACTACTATAAAAAAGAGTGAAAAAACACTACAGGAAGAAACCAACGATTCATATGAAAATGATATTATAGAAGAACTTATCGAAGAATTAGATATCATTGAGGAAATTGCCGAAGAAGATGATGGTGAGTGTttcaatgaagaaaatttaacaaatagaAAGATCGTCCTATCGCAAGCAACTTACAACGAAGGTGATTATTTAAccgacaatttaaaaatatcgttcgaatgtaaatattgttataaatggAAAAACAGCACTTCTGAAAATTTTCTTACTCAGCAAGATCTTTTGGCTCACATAACCAAACTACACAGTTCGGAACAGCCATATAATTGTCCTTACTGCAAGCAAACATTCATGGATGCCGCCTCAAGGACGACTCATTTAAAAGAAGAGCATAGTCAAAAAGTGTATGAGTGTGAAACTTGTGGTAAAAAATATGcagataaatttaatttaaaaaatcacattGAAAAGTATCATAGTGGCACTGATTTCGATTGCACGCTTTgtgagaaaagtttttgttccaGAAAAAGTTTGAATTATCACATGAAATGGCATAATCCAAAGGAACAATTGAAGTGTAGCTACTGTGATCGTTTATTTATCAATCAGAGACATTTAAAGTCGCATGAGGAAACTCACACAGGATTTCGTAGTCAGGAGGTCTGTTCATTTTGTGGGAAAAattttttccatttaaaaactCTGAGATGGCATATTTACCGCCAACATGGTGGTGATAAACCATATAAATGTGCCAGATGCACAGAAGtCTTCACGTCATATTTTGAAAAACGTATACACATGCTCGAATATCATTTAGACAATCTAACACTGATCGAAAAAACTGAATGCATGTTATGCCATAAACGTTATGACAATGAACAGGAACTCAAGGATCATATGTTGGAGGATCATAAGGAAAATAAGGGAgcagtaaaaataacaaataacaaaagagTCATTATGAACAAGAAACCAAAAAGTTTTACAGGAATATTTCAATGTGAAAAATGTGATAAAAGATTTAATATGAAATCAGCTCTAGAGAGGCACTTGGCTGTACATTCCATAGAGGGAAGACCTCATGCATGTCCACAATGCCCTAAGCGCTTTAAACGTTCACAAGATATGAAGTGGCATTTAAAAACACATTCTTCagagaaacaaaatatatgCGATGTTTGTGGGAAAGGATTTGctttaaagtatgttttaacTCAGCATCGCCGAAGTCATGaagttttagAAAAGAACTTCACCTGCTCCACGTGTGGTCGTTCCTATCTTTTCGAGAAGTCCTTGCGTTTACATGAACGCATACATAGTGGCAAAACTTACTATAAATGTGACTTATGCAGTGAAAATTTTGTTAcacacattaaatttaaatGGCATATGAAAAAAATGCATGACGAAGAAGAAGTTGCCGCCACAGATTTAAATCCTAATAAAACTAAATCCAAAATTGAGCTGCCATTGGACGATTTGGTCAACATTGTGATTacttaa
Protein Sequence
METCRTCAKCDFDNESQWFDLFNAPRWQIEMQRIHLELNAWKIKISCNDGLPQKICPDCFSKFCTVSSFREQCLEAQTSLSNIFDKIDTQCIQGEEEQEVFEGFPNEQDNNAQSTVTTVIHSATAVVATATAAAKTIEHTFETTEKSNISSNSGCNSNNNNESIISFSEILNLNRKNNTDTSVRNIEKLPDTALLKNKIKNFNHIFEELEDIENNPVDHDVEDACSKTITTIKKSEKTLQEETNDSYENDIIEELIEELDIIEEIAEEDDGECFNEENLTNRKIVLSQATYNEGDYLTDNLKISFECKYCYKWKNSTSENFLTQQDLLAHITKLHSSEQPYNCPYCKQTFMDAASRTTHLKEEHSQKVYECETCGKKYADKFNLKNHIEKYHSGTDFDCTLCEKSFCSRKSLNYHMKWHNPKEQLKCSYCDRLFINQRHLKSHEETHTGFRSQEVCSFCGKNFFHLKTLRWHIYRQHGGDKPYKCARCTEVFTSYFEKRIHMLEYHLDNLTLIEKTECMLCHKRYDNEQELKDHMLEDHKENKGAVKITNNKRVIMNKKPKSFTGIFQCEKCDKRFNMKSALERHLAVHSIEGRPHACPQCPKRFKRSQDMKWHLKTHSSEKQNICDVCGKGFALKYVLTQHRRSHEVLEKNFTCSTCGRSYLFEKSLRLHERIHSGKTYYKCDLCSENFVTHIKFKWHMKKMHDEEEVAATDLNPNKTKSKIELPLDDLVNIVIT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2