Basic Information

Insect: Cheilosia vernalis
Gene Symbol: -
Assembly: GCA_949126925.1
Location: OX421360.1:6722937-6729736[+]

Transcription Factor Domain

TF Family: MBD
Domain: MBD domain
PFAM: PF01429
TF Group: Unclassified Structure
Description: The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 6e-13 3.9e-09 36.8 0.1 9 71 184 242 177 246 0.85

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	6e-13	3.9e-09	36.8	0.1	9	71	184	242	177	246	0.85

Sequence Information

Coding Sequence: ATGGAAGTGGACGCTACGATCCAGGAAGAATTCGTCGAAGAAGAAGTCGATTACATTTCCGCCATGAAACTGGCCGTGTCTGAGGATGAGGAGGGTGGTGGTGATGCCGAAGAAGTAAGTGGGGGCAGTCGAATGGATACCACTACCACGAAGACGTCAAATCGGGAAAATGGTGGATCTGGCGACATGGCAAGTTGCAGCAAACAGAAACCCAATTACAATTTAAACGAAGTGTCGGGAGAGGAGCTTATGGGTTTTGAAGAATATACTTGGAAGCCCATATATGCTGAGATACTGGCcagtcaaattgatgttgttGAGGATAGCTCGGACACGAAGGTGGAATCAGAAAGTGAGTGTGATGTGGTGCCGCCGCCTAAAAAGAGTAGACTATCCGAAGACTCTGCAGATACTTTGGAAGAACGGAAGGCTTCGTTGTCCCCCTCAACGTCGGGTGTGTCGCCAACCCATCCTCCTGTCACTACGCCCGTTGTCCCAGTTGTCCCAGCAGCGCTCAAGTTGAAAACACCGAAAGACGAATTCTACAAGAAACCCTTTGAGTTTGGATGGAAGCGCGAACTTGTTTATCGCGCAAATCCCGACGTTAGCAAGGACAAGGCCGACGTGTACTTCATCTCGCCGTCCGGCAAGAAGCTGCGGTCGAAAAATGAAATAACTCCCCTCCTGGACGGCGACCTGACAATCGAACATTTTTGCTTCGCCAAGGAACCACAGGGCTTGAGCGTTGACCTGGAGATCGTTCGCAGTGCAAAGCCAACACATCGCGCCGCTGCTGAAATCATCAACATTAGCAGCAGTAGTACGAGCAGCGGAAAAAGAGTTTCCAAGCCGAAAGCACCTAAAGGGGCCTCACCACCGCCACAGGGATGGACGCCTACACGAGCCTTAAAGAGCTCGTCTTCACTGAACACGAACTCGAACTCAAATGCGACGGCTGGCAACGCGGCAGCCTCACCCAAAAACACGCCCAAGTCCAGCAAGAGCAGAAAAGTCGGAGATCCACAACCCTGCACGATGCAGTGTGCCGCTGCAATGGGAATGATACCGCAATTGCAGTGCATCAAGTGCCTTTGCCTCTTCCACCATGAGTGTGTCGGCCTGGACCAAAAGGACACCCAGTATCGGTTGGTGGCGGCGCTGGATGCCGGCCAGGGGCATCACCACCACCGGAAGGACTACGTCTGTCAGTCCTGCATTCCGCCAGCAGAAGTGCCCGTGTTGAAGGAAAATCAAGTAAACGCCAAGGAACCGGGCAGTCAAATCCTATTCAGCGCGCTGTCCCAATTGCCGCCACTGCCTGCAGCACCCGTCGTTCCGGTGGCTCCAACTCCAACGATTGCCACGCCAGTGATTGCTCCAATTTCCAAGGCACCAACGAGCACACCGCCCGAACCAGCTGTCGGTGATCTACCTCAGTCAATCGCCGTAATAAAGGGCAAGAAGTACGTCGTCGTGAAAAAGCCCTTGAACCTACGTTCCGCAGCCGCCACACTGGCTCCTGAgaccaacaacaataacaatgcGGAGGCGGTAGCAGAAAACGACGTTATCACAAATGACCGCTCCAAGCGTAATCATTCGTCAAATTCACACCGAAAAAACCCGACAGCTACATCGGCAAATGCAATACAGACGACAGTCACAGCAGCTGTGCAAAGCTCACCGCCAGGGAACAGTACCAATCACGCCCAGCAGACGACCCGCCTGCCGGAGTCGGCGTCTCTAACGTTCGCGTCTAACTTCTTTGCGAATGTCTCCGTGGGATACGGCGCTATACTACATATACTGAAGTATTTGAAGATTCAcGAACGTCCGCGTGCAGCGTCAGTGTGTAAAATTTGGAACCTGGTAGCAAAGGATCGCTCTCTGTGGCAAACGGTTCGTATGAAGAACTCCAAAGTGAGTAACTGGGCCGGCTTCACAGCGGCTCTACGGCGCGGCGAGACCAAGCACTTAGATCTGCGTAAACTCTTGGTCTCCAGCACCAAGGTTGAGGAAACATGGTCCGACTTTTGCAAATACATTGGCGGGGTCACCTCGCTGGAACAAATTGACATGTGTCGCTGCTCGGCGCTCGTAGTGGAAACACTCTTCGTGACAAATACCAATCTAACCATTCTAAGTGCATTGGCGATAAACGATGACACCATAAATTTGGTGAACATAGGCAACCTCGTGTTGTTGGAGGAGCTGCGTCTACGCACATTGGAGAAGTGCACACTCACAGGGGACCTCTCGCCGCTGCGCGCACTGAAAAATCTTCGTCATCTAACGCTGTCGTCGGTGCGACAACTCGGCACCAAGGCGATCGAAATAATCGGAGAACTGGAAAGCCTTGTCTCCTTGGAACTGGGTGAGTGCAATGACTTTGATTCGCGATTCACCGACAGTGTATTGCCGAAGCTGTCGAACTTGGAGCGGTTACGCTTGGAAATTGGCCAGGAGCAGTGTCGCACTTTGGATATCTTAGACTCAGTCGCTAAGCTGGAGAAACTTAGCCAGCTAGAGTTTGTTAACTTTGACATCAAGCCGGGATTCGACGACAAACTGTCTCAATGTACAAACATTCGGAAGTTGTTGATCATCCCCACATACATCTCGCAATCAGCCACCACCAACAACATCGTACTGAACGCTGTACTGAAACTTAAAGACACACTGCAAGTATTCACCTGGGGCGTCACTGTGGAGCTGCTGCGCGTAACCGCACTGTACGTGGACCAATGTGAGGACTCCACACGAAAGGAGCGGCGCCATTTCGACGAATGTATTCCGGTGCTGAAGCCAGTGCCGGGATCGGCTGCTGCCGAATCAATAGGCGATGAGCCCAGCACCGGGGCAAATGCAGTACCGCAGATTGAGATTCTGCCGCTGGATAAAGTTGAGGAAATCCTGAACGATCACCTCTCAACCACAAAGTTCACGATTGTGAAAGTGCCGTACCATGCTACGTGGAAGCAGCAACTCGTCGAATAG
Protein Sequence: MEVDATIQEEFVEEEVDYISAMKLAVSEDEEGGGDAEEVSGGSRMDTTTTKTSNRENGGSGDMASCSKQKPNYNLNEVSGEELMGFEEYTWKPIYAEILASQIDVVEDSSDTKVESESECDVVPPPKKSRLSEDSADTLEERKASLSPSTSGVSPTHPPVTTPVVPVVPAALKLKTPKDEFYKKPFEFGWKRELVYRANPDVSKDKADVYFISPSGKKLRSKNEITPLLDGDLTIEHFCFAKEPQGLSVDLEIVRSAKPTHRAAAEIINISSSSTSSGKRVSKPKAPKGASPPPQGWTPTRALKSSSSLNTNSNSNATAGNAAASPKNTPKSSKSRKVGDPQPCTMQCAAAMGMIPQLQCIKCLCLFHHECVGLDQKDTQYRLVAALDAGQGHHHHRKDYVCQSCIPPAEVPVLKENQVNAKEPGSQILFSALSQLPPLPAAPVVPVAPTPTIATPVIAPISKAPTSTPPEPAVGDLPQSIAVIKGKKYVVVKKPLNLRSAAATLAPETNNNNNAEAVAENDVITNDRSKRNHSSNSHRKNPTATSANAIQTTVTAAVQSSPPGNSTNHAQQTTRLPESASLTFASNFFANVSVGYGAILHILKYLKIHERPRAASVCKIWNLVAKDRSLWQTVRMKNSKVSNWAGFTAALRRGETKHLDLRKLLVSSTKVEETWSDFCKYIGGVTSLEQIDMCRCSALVVETLFVTNTNLTILSALAINDDTINLVNIGNLVLLEELRLRTLEKCTLTGDLSPLRALKNLRHLTLSSVRQLGTKAIEIIGELESLVSLELGECNDFDSRFTDSVLPKLSNLERLRLEIGQEQCRTLDILDSVAKLEKLSQLEFVNFDIKPGFDDKLSQCTNIRKLLIIPTYISQSATTNNIVLNAVLKLKDTLQVFTWGVTVELLRVTALYVDQCEDSTRKERRHFDECIPVLKPVPGSAAAESIGDEPSTGANAVPQIEILPLDKVEEILNDHLSTTKFTIVKVPYHATWKQQLVE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00311057;
90% Identity: iTF_00311820; iTF_00311057; iTF_00314311; iTF_00315186;
80% Identity: -