Cgro007102.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Cheilosia grossa
Gene Symbol
-
Assembly
GCA_963082955.1
Location
OY720145.1:3067458-3073818[-]

Transcription Factor Domain

TF Family
MBD
Domain
MBD domain
PFAM
PF01429
TF Group
Unclassified Structure
Description
The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 7.3e-13 2.8e-09 36.8 0.1 9 71 187 245 180 249 0.85

Sequence Information

Coding Sequence
ATGGAAGTGGACGCTACGATCCAGGAAGAATTCGTCGAAGAAGAAGTCGATTACATTTCCGCCATGAAACTGGCCGTGTCCGAAGATGAGGAGGGTGGTGGTGACGCCGAAGAAGTAAGTGGGGGCAGTCGAATGGATACCACTACCACGAAGACGTCAAATCGGGAAAATGGTGGATCTGGCGACATGGCAAGTGGCAGCAAACAGAAACCGAATTACAGTATAAACGATGCGTCGGGAGATGAGCTTATGGGGTTCGAAGATTATACTTTGAAGCCCATATATGCTGATATTATAGTGGCCAGTCAAATGGATGTTGTTGAGGACAGCTCGGACATGAAGGTGGAATCAGAAAGTGAGTGTGATGTGGTGCCGCCGTCTAAAAAGAGTAGGCTATCCGAAGACTCTGCAGACACTTTGGAAGAACGGAAGGCTTCGGTGTCCCCCTCAACGTCGGGTGTGTCGCCAACACCAACACATTCTTCTGTCACTTCGCCCGTTATCCCAGTTGTCCCAGAAGCgcccaagttgaaaacaccgaAAGATGAATTCTACAAGAAACCCTTTGAGTTTGGATGGAAGCGCGAACTTGTTTATCGCGCAAATCCCGACGTTAGCAAGGACAAGGCCGACGTGTACTTCATCTCGCCGTCCGGCAAGAAGCTGCGCTCGAAAAACGAAATAACTCCACTCCTGGACGGCGACCTGACAATCGAGCATTTTTGCTTCGCCAAGGAACCACAGGGCTTGAGCGCTGACCTGGAGATCGTTCGCAGTGCAAAGCCAACACATCGGGCCGCTGCCGAAATcatcaacatcagcagcagTACGAGCAGCGGAAAGAGAGTTTCCAAACCGAAAGCACCTAAAGGGGCCTCGCCACCGCCACTGGGATGGACGCCCACACGAGCCTTAAAGAGCTCGTCTTCACTGAACACGAACTCGAACCCAAACGCGACGGCTGGCAACGCGGCAGCCTCACCCAAAAGCACGCCCAAGTCCAGCAAGAGCAGAAAaGTCGGAGATCCACAACCTTGCACGATGCAGTGTGCCGCTGCAATGGGAATGATACCGCAATTGAAGTGCATCAAGTGCCTTTGCCTGTTCCACCACGAGTGCGTCGGCCTGGACCATAAGGACACCCAGTATCGGTTGGGGGCGGCGCTGGGTGGCGGAGAGGGGCCTCACCACCACAGGAAGGACTACGTCTGTCAGTCCTGCATTCCGCCAGCCGAAGTGCCTGTGTTGAAAGAAAATCAAGTAACCGCCAAGGATCCGGGCAGTCAAATCCTATTCACCGCGCTGTCCCAATTGCCGCCACCGCCTGCAGCACCCGCCGTTCCGGCAGCTCCAACTCCAACAGCAACGTTTGCCACTCCAGCGATTGCTCCAATTTCCAAGGCACCAACGAGCACACCTCCCGAACCAGCTGTCGGTGATCTGCCTCAGTTAATCGCCGTAATCAAAGGCAAGAAGTACGTCGTCGTGAAAAAGCCCTTGAACCTACGTTCCGCAGCCGCCACACTGACTCCTGAAACCAACAACATGAACATTGCGGAGGCGGTAGCAGAAAACGACGTTATCCCAAATGATCGCTCCAAGCGGAATAATTCATCAAATTCACATCGAAAGAACCCGACAGCTGCCTCGGCAAATGCAATACAGATGACAGCCACAGCAGCTGTGCAAAGCTCACCGCCAGGGAACAGTACCAATCACGCCCAGCAGACAACCCGCCTGCCAGAGTCGGCGTCTCTAACGTTCGCGTCTAACTTCTTTGCGAATGTCTCCGTGGGATACGGTGCTATACTACACATACTGAAGTATTTGAAGATTCacGAACGTCCGCGTGCAGCGTCAGTGTGCAAAATTTGGAATCTGGTCGCAAAGGATCGCTCCCTGTGGCAAACGGTGCGTATGAAGAACTCCAAAGTGAGTAACTGGGCCGGCTTCACAGCGGCCCTACGGCGCGGCGAGACCAAGCACTTAGATCTGCGTAAACTCTTGGTCTCCAGCACCAAGGTGGAAGAGACCTGGTCAGACTTTTGCAAATACATTGGCGGAGTCACCTCGCTGGAACAAATCGACATGTGCCGCTGCTCGGCGCTGGTGGTGGAAACCCTCTTCGTGACAAATACCAATCTAACCATTCTAAGTGCATTGGCTATAAACGATGACACCATAAATTTGGTGAACATAGGCAACCTCGTGTTGTTGGAGGAGCTGCGTCTTCGCACATTGGAGAAGTGCACGCTCACAGGGGACCTCTCGCCGCTGCGCGCGCTGAAAAATCTCCGTCATCTAACGCTGTCGTCGGTGCGACAACTCGGCACCAAGGCGATCGAAATAATCGGTGAACTGGAAAGCCTTGTCTCCTTGGAACTGGGCGAGTGCAATGATTTTGATTCGCGATTCACCGACAGTGTATTGCCGAAACTGTCGAACTTGGAGCGGTTACGCTTGGAAATTGGCCAGGAGCAGTGTCGCACTTTGGATATCCTAGACTCAGTCGCTAAGCTGGAGAAACTTAGCCAACTAGAGTTTGTTAACTTTGACATCAAGCCAGGATTCGACGACAAACTGTCTCAATGTACAAACATTCGGAAGCTGTTGATCATCCCTACATACATCTCGCAATCagccaccaccaacaacatagtACTGAACGCCGTACTGAAACTGAAAGACACACTGCAAGTATTCACCTGGGGCGTCACTGTGGAGCTGCTGCGTGTCACCGCACTGTACGTGGACCAATGTGAGGACTCCACACGAAAGGAGCGGCGCCATTTCGACGAATGTATTCCGGTGCTGAAGCCAGTGCCCGGATCGGCTGCTGCCGAATCAATAGGCGATGAGCCCAGCACCGGGGCAAATGCAGTACCGCAGATTGAGATTCTGCCGCTGGACAAAGTTGAGGAAATTCTGAACGATCACCTCTCAACCACAAAGTTCACGATTGTGAAAGTGCCGTACCATGCTACGTGGAAGCAGCAACTCGTCGAATAG
Protein Sequence
MEVDATIQEEFVEEEVDYISAMKLAVSEDEEGGGDAEEVSGGSRMDTTTTKTSNRENGGSGDMASGSKQKPNYSINDASGDELMGFEDYTLKPIYADIIVASQMDVVEDSSDMKVESESECDVVPPSKKSRLSEDSADTLEERKASVSPSTSGVSPTPTHSSVTSPVIPVVPEAPKLKTPKDEFYKKPFEFGWKRELVYRANPDVSKDKADVYFISPSGKKLRSKNEITPLLDGDLTIEHFCFAKEPQGLSADLEIVRSAKPTHRAAAEIINISSSTSSGKRVSKPKAPKGASPPPLGWTPTRALKSSSSLNTNSNPNATAGNAAASPKSTPKSSKSRKVGDPQPCTMQCAAAMGMIPQLKCIKCLCLFHHECVGLDHKDTQYRLGAALGGGEGPHHHRKDYVCQSCIPPAEVPVLKENQVTAKDPGSQILFTALSQLPPPPAAPAVPAAPTPTATFATPAIAPISKAPTSTPPEPAVGDLPQLIAVIKGKKYVVVKKPLNLRSAAATLTPETNNMNIAEAVAENDVIPNDRSKRNNSSNSHRKNPTAASANAIQMTATAAVQSSPPGNSTNHAQQTTRLPESASLTFASNFFANVSVGYGAILHILKYLKIHERPRAASVCKIWNLVAKDRSLWQTVRMKNSKVSNWAGFTAALRRGETKHLDLRKLLVSSTKVEETWSDFCKYIGGVTSLEQIDMCRCSALVVETLFVTNTNLTILSALAINDDTINLVNIGNLVLLEELRLRTLEKCTLTGDLSPLRALKNLRHLTLSSVRQLGTKAIEIIGELESLVSLELGECNDFDSRFTDSVLPKLSNLERLRLEIGQEQCRTLDILDSVAKLEKLSQLEFVNFDIKPGFDDKLSQCTNIRKLLIIPTYISQSATTNNIVLNAVLKLKDTLQVFTWGVTVELLRVTALYVDQCEDSTRKERRHFDECIPVLKPVPGSAAAESIGDEPSTGANAVPQIEILPLDKVEEILNDHLSTTKFTIVKVPYHATWKQQLVE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00312614; iTF_00313479; iTF_00314311; iTF_00315975; iTF_00311820; iTF_00315186;
90% Identity
iTF_00315975;
80% Identity
-