Basic Information

Insect: Cheilosia urbana
Gene Symbol: -
Assembly: GCA_946477595.1
Location: CAMLCJ010000109.1:268277-279104[+]

Transcription Factor Domain

TF Family: MBD
Domain: MBD domain
PFAM: PF01429
TF Group: Unclassified Structure
Description: The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 6.7e-13 4.9e-09 36.9 0.1 9 71 184 242 177 246 0.85

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	6.7e-13	4.9e-09	36.9	0.1	9	71	184	242	177	246	0.85

Sequence Information

Coding Sequence: ATGGAAGTGGACGCTACTATCCAGGAAGAATTCGTCGAAGAAGAAGTCGATTACATCTCCGCCATGAAACTGGCCGTGTCCGAGGATGAGGAGGGAGGTGGTGATGCCGAAGAAGTAGGTGGGGGCAGTCGAATGGATACCACTACCACGAAGACATCAAATCAGGAAAATGGTGGACCTGGCGACATGGCAAGTGGCAGCAAACCGAAACCGAATTTCAATATAAACGATGTGTCGGGAGATGAGCTCATGGGATTCGAAGAATATATTTTGAGGCCCGTATATGCTGAGACAGTGGTCAATCAAATGGATGTTGTTGAGGACAGTTCGGACACGAAGGTGGAATCAGAAAGTGAGTGTGATGTGGTGCCGCCGCCTAAAAAGAGTCGGCTATCCGAAGACGCTGCGGATACTTCGGAAGAACTGCAGGCTCCGTTGTCACCCTCAACATCGGGTGTGTCGCCAACATATCCCCCTGTCACTACGCCCGTTGTCCCAGTTGTCCCAGCAGCACTCAAGTTGAAAACACCGAAAGACGAATTCTACAAGAAACCCTTTGAGTTTGGATGGAAGCGCGAACTTGTTTATCGCGCAAATCCCGACGTAAGCAAAGACAAGGCCGACGTGTACTTCATCTCGCCGTCCGGCAAGAAGCTGCGCTCGAAAAACGAAATAACTCCCCTCCTGGAAGGCGACCTGACAATCGAACATTTTTGCTTCGCCAAGGAACCACAGGGCTTGAGCGCTGACCTGGAGATCGTTCGCAGTGCAAAGCCAACACATCGCGCCGCTACCGAAATCGTCAACATCAGCAGCAGTACGAGCAGCGGAAAGAGAGTTTCCAAACCGAAAGCACCTAAAGGGGCTTCGCCACCGCCACAGGGATGGACGCCTACTCGAGCCTTAAAGAGCTCGTCTTCACTGAACACGAACTCGAACTCAAATGCGACGGCTGGCAACGCGGCAGCCTCACCGAAAAGCACGCCCAAGTCCAGCAAGAGCAGAAAagTCGGAGATCCACAACCCTGCACGATACAGTGTGCCGCTGCAATGGGAATGATACCGCAATTGCAGTGCATCAAGTGCCTTTGCCTGTTCCACCACGAGTGCGTCGGCCTGGACCATAAGGACACCCAGTATCGGTTGGTTGCGGCGCTGGTTGGCGGCCAGGGGCATCACCACCACAGGAAGGACTACATATGTCAGTCTTGCATTCCGCCAGCAGAAGTGCCTGTGTTGAAAGAAAATCAAATATCCGCCAAGGATCCGGGCAGTCAAATCCTATACAGCGCGCTGTCCCAATTGCCGCCACCGCCTGCAGCACCCGCCGTTCCGGTAGCTCCAACTCAACCGATCGCCTCGCCACCGATTGCCCCAACTTCCAAGGCACCAACGACAGCAGTCGAACCAGGGGTCGGTGATCTACCACAGTCAATCGCCGTAATCAAAGGCAAGAAGTACGTCGTCGTGAAAAAGCCATTAAACATGCGTTCCACAGCCGCCACACTGGCTTCTGAaaccaacaacaacaacaatgcgGAGGCGGTAGCAGAAAACGACGTTATCACAAGTGATCGCTCAAAGCGTAATCATTCATCAAATTCACACCGAAAAAACCCGACAACTGCATCAGCAAATGCAATTCAGGCGACAGCCACAGCAGCAGTGCAAAGCTCACCGCCACGGAACAGTACCAATAACGCTCAGCAGACGACCCGCCTGCCGGAGTCGGCGTCTCTAACGTTCGCGTCTAACTTCTTTGCAAATGTCTCCGTGGGATACGGTGCTATACTACATATACTGAAGTATTTGAAGATTCacGAACGTCCGCGTGCAGCGTCAGTGTGTAAAATTTGGAATCTGGTAGCAAAGGACCGCTCTCTGTGGCAAACGGTACGTATGAAGAACTCCAAAGTGAGTAACTGGGCCGGCTTCACAGCGGCCCTACGACGCGGCGAGACCAAGCACTTGGATCTGCGTAAACTCTTGGTCTCCAGCACCAAGGTTGAAGAAACCTGGTCAGACTTTTGCAAATACATTGGCGGTGTCACCTCGCTGGAACAAATTGACATGTGCCGCTGCTCGGCGCTGGTGGTGGAAACCCTCTTCGTGACAAATACCAATCTAACCATTCTAAGTGCACTGGCGATAAACGATGACACCATCAATTTGGTGAACATAGGCAACCTCGTGCTGTTGGAGGAGCTGCGTCTACGCACATTGGAGAAATGCACGCTCACAGGGGACTTGTCGCCGCTGCGCGCGCTGAAAAATCTTCGTCATCTGACGCTGTCGTCGGTGCGACAACTCGGCACCAAGGCGATCGAAATAATCGGTGAACTGGAAAGCCTCGTCTCCTTAGAACTGGGCGAGTGCAATGACTTTGATTCAAGATTCACCGACAGTGTATTGCCGAAGCTGTCGAACTTGGAGCGGTTACGCTTGGAAATTGGCCAGGAGCAGTGTCGCACTTTGGATATCTTAGACTCAGtcgctaagctggagaaacttagcCAGCTGGAGTTTGTTAACTTTGACATCAAGCCAGGATTCGACGACAAACTGTCTCAATGTACAAACATTCGGAAGCTGTTGATCATCCCCACATACATCTCACAATCAGCCACCACCAACAACATCGTACTGAACGCTGTGCTGAAACTGAAAGACACACTGCAAGTATTCACCTGGGGCGTCACTGTGGAGCTACTGCGCGTCACCGCACTGTACGTGGATCAATGTGAGGACTCAACACGAAAGGAGCGGCGACATTTCGACGAATGTATTCCGGTGCTGAAACCAGTGCCCGGATCGGCTGCTGCCGAATCCGTAGGCGATGAGCCCAGCACCGGTGCAAATGCAGTACCGCAGATTGAGATTTTGCCGCTGGACAAAGTTGAGGAAATTCTGAACGATCATCTTTCAACCACAAAGTTCACGATTGTAAAAGTGCCCTACCATGCTACGTGGAAGCAGCAACTCGTCGAATAG
Protein Sequence: MEVDATIQEEFVEEEVDYISAMKLAVSEDEEGGGDAEEVGGGSRMDTTTTKTSNQENGGPGDMASGSKPKPNFNINDVSGDELMGFEEYILRPVYAETVVNQMDVVEDSSDTKVESESECDVVPPPKKSRLSEDAADTSEELQAPLSPSTSGVSPTYPPVTTPVVPVVPAALKLKTPKDEFYKKPFEFGWKRELVYRANPDVSKDKADVYFISPSGKKLRSKNEITPLLEGDLTIEHFCFAKEPQGLSADLEIVRSAKPTHRAATEIVNISSSTSSGKRVSKPKAPKGASPPPQGWTPTRALKSSSSLNTNSNSNATAGNAAASPKSTPKSSKSRKVGDPQPCTIQCAAAMGMIPQLQCIKCLCLFHHECVGLDHKDTQYRLVAALVGGQGHHHHRKDYICQSCIPPAEVPVLKENQISAKDPGSQILYSALSQLPPPPAAPAVPVAPTQPIASPPIAPTSKAPTTAVEPGVGDLPQSIAVIKGKKYVVVKKPLNMRSTAATLASETNNNNNAEAVAENDVITSDRSKRNHSSNSHRKNPTTASANAIQATATAAVQSSPPRNSTNNAQQTTRLPESASLTFASNFFANVSVGYGAILHILKYLKIHERPRAASVCKIWNLVAKDRSLWQTVRMKNSKVSNWAGFTAALRRGETKHLDLRKLLVSSTKVEETWSDFCKYIGGVTSLEQIDMCRCSALVVETLFVTNTNLTILSALAINDDTINLVNIGNLVLLEELRLRTLEKCTLTGDLSPLRALKNLRHLTLSSVRQLGTKAIEIIGELESLVSLELGECNDFDSRFTDSVLPKLSNLERLRLEIGQEQCRTLDILDSVAKLEKLSQLEFVNFDIKPGFDDKLSQCTNIRKLLIIPTYISQSATTNNIVLNAVLKLKDTLQVFTWGVTVELLRVTALYVDQCEDSTRKERRHFDECIPVLKPVPGSAAAESVGDEPSTGANAVPQIEILPLDKVEEILNDHLSTTKFTIVKVPYHATWKQQLVE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00311057;
90% Identity: iTF_00315975;
80% Identity: -