Basic Information

Insect: Chalcosyrphus nemorum
Gene Symbol: lrrfip2
Assembly: GCA_949716465.1
Location: OX454332.1:2267540-2274941[+]

Transcription Factor Domain

TF Family: LRRFIP
Domain: LRRFIP domain
PFAM: PF09738
TF Group: Unclassified Structure
Description: LRRFIP1 is a transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'- AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA [1]. LRRFIP2 may function as activator of the canonical Wnt signalling pathway, in association with DVL3, upstream of CTNNB1/beta-catenin [2].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 0.15 3e+03 -2.7 0.1 130 173 19 64 11 90 0.66

2 3 3.7e-116 7.3e-112 373.7 32.8 1 299 146 436 146 437 0.93

3 3 0.098 1.9e+03 -2.0 4.4 220 244 465 489 441 511 0.45

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	0.15	3e+03	-2.7	0.1	130	173	19	64	11	90	0.66
2	3	3.7e-116	7.3e-112	373.7	32.8	1	299	146	436	146	437	0.93
3	3	0.098	1.9e+03	-2.0	4.4	220	244	465	489	441	511	0.45

Sequence Information

Coding Sequence: ATGTCGGAAGTGTTGAAACAATCCAACGGATTGATCTATGATCAACGCAATACCGCGGAGGAGgagaataataatttgaaaaacacACCGGATTATGATGAAATCGGTGAGGAATTCGATTTCAGTGATAGTGATTTGAGTGAACTAAACGGTGACAATAGTGTCACCAAAAATGATATAAATTCAAGTGATGTTTGTGATACTGTCAATAAAGAGGTTTTGATAACAAAGCCCGCTAATCTAAGCCTGGAACAGGCGAAAGAAGTCCCAACCGATTCATTTTGTCCAATAACACCGCGAAAAATTGTCGACTGCAAGGAGAGCGATGGCATGGAGAACTCTTCCAATGGATATACCAGTGATGGAATGGAAGACGATGTGCAAGATGAGGATGACGAGCTGATTGTACAATTTTTAGGACAAGCTAATCAAATGGCTGAAGCGAGGCTGGCAGCTAGACGACAGGCACGTGCAGAAGCGCGGGAAATTCGCATGCGCGAATTGGAACGCCAACAAAAAGAGCAAGAACAAAATGCCGATCGGGTATTCGACATGCAAACCGCAGCTGGTATTGACCCTTTGGCTAGGTCGCGTCTCACCGCGGCCAGTATTACCGGTGTGGTCAATTCTGTCCGCGCTAGTTCGATGTCTTCCCGCCGAAGCAGTGAAGATTCCCTGGAGGAGGAAGGGCGCAGCTTACGTGATATTAGGCATGAACTCAAGgatgTCGAGGAACGCTTTAGAAAAGCAATGATAGCCAATGCGCAGTTGGATAATGAAAGAGCCTCACAATCCTATCAAATTCAACTGCTTAAGGATAAACTCGAGGAAATGGAAGAATCATTTGCCCAGCTACAGCGTGAATTCAAAGAAAAGACACGCGAATGCAATGCTCTCAAGCGTAACCTTGACAAATTGACGGAAGAATTAAAGCTCGTTCATGGTCAGCTAACTGAACGAGATGCACTTATAGCTGAACAGGGTTTGGTTATTGTAGCTGTAGAAAATGAGGATGGCTCAGATGCCAAACGTGCTCTAGTCACTATAGAGAATGCACAATTGTTGGGTTCTGTACAAGGTTCTCTGGATGTTCGACTTAAGAAATTTAGTGAAGAAAAACagcaacttcaagctgaagtgCAAAATTTACAGGAACAATTAGAAAATGTTAAGACACAGGGACGAGGTCGGGGAAATTCAATGAACGGCCCATTGGGATCCGACGACGATTATGAAGCTCAAAGGGAAGCAAATAAGATCATCTCCGACTATAAATATAAACTGCAGAAGGCCGAACAAGAAATCGCTAGTCTACAAGCCAGCTTAGCTAGATCAGAAACACAAGTTATACGATATAAGAGTACAGCGGAAGCCGCTGAAAAAGCCGAGGCTGAGTTGAAAATCGAAAGGAGAAAGCTTCAACGCGAGaatcgTGAAGCAATGGAGCGGCTAGAGGAACTAGAAACATCTAACAATCATCTATTAAAACGACTGGATAAATTAAAGAATGCCAAGAGTGCGCTTCTCAAAGAACTTTGA
Protein Sequence: MSEVLKQSNGLIYDQRNTAEEENNNLKNTPDYDEIGEEFDFSDSDLSELNGDNSVTKNDINSSDVCDTVNKEVLITKPANLSLEQAKEVPTDSFCPITPRKIVDCKESDGMENSSNGYTSDGMEDDVQDEDDELIVQFLGQANQMAEARLAARRQARAEAREIRMRELERQQKEQEQNADRVFDMQTAAGIDPLARSRLTAASITGVVNSVRASSMSSRRSSEDSLEEEGRSLRDIRHELKDVEERFRKAMIANAQLDNERASQSYQIQLLKDKLEEMEESFAQLQREFKEKTRECNALKRNLDKLTEELKLVHGQLTERDALIAEQGLVIVAVENEDGSDAKRALVTIENAQLLGSVQGSLDVRLKKFSEEKQQLQAEVQNLQEQLENVKTQGRGRGNSMNGPLGSDDDYEAQREANKIISDYKYKLQKAEQEIASLQASLARSETQVIRYKSTAEAAEKAEAELKIERRKLQRENREAMERLEELETSNNHLLKRLDKLKNAKSALLKEL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00315970;
90% Identity: iTF_00313474;
80% Identity: -