Cova014075.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Chaetogeoica ovagalla
Gene Symbol
-
Assembly
GCA_032441825.1
Location
CM063738.1:10066750-10073159[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 9 8.4 8.7e+02 1.1 2.5 1 10 272 281 272 283 0.90
2 9 2.9e-08 3e-06 27.7 0.9 1 23 307 329 307 329 0.98
3 9 3.2e-05 0.0033 18.1 2.3 1 23 335 357 335 357 0.98
4 9 4.3e-06 0.00044 20.9 0.5 1 20 363 382 363 383 0.95
5 9 0.0001 0.011 16.5 6.9 1 23 398 421 398 421 0.97
6 9 2.7e-06 0.00027 21.5 5.4 1 23 438 460 438 460 0.97
7 9 1.3e-06 0.00013 22.5 3.9 3 23 528 549 527 549 0.98
8 9 3.8e-06 0.00039 21.0 3.3 2 23 577 599 576 599 0.94
9 9 3.8e-05 0.0039 17.9 0.2 1 23 609 631 609 631 0.98

Sequence Information

Coding Sequence
ATGGAATACGACGAAGACGATGGCCCGCAAGaggaaacgacgacgacggcggcggcggccgcggtTATCAGCAGTTGCTGCAGGTTGTGCTGCAAACCGTCGACGGACGTAGACGGACGGCATCGGATCATCGTTGACAATAGggacaacaacaacgacgacgacgacgatgacgacgatggcggcggcggcgggacaCGCCCCGACGGTCGCGATTTACGCGGCATCATTGTCAAGCACCTGCGGATACAGGTCACAGAAGACGATGGTTTGTCCAAGATTATATGCTCCGAATGTTTGGGATTTCTAAACGAATGGAGTCAGTTTTACGAGATGTGctcgaaaaacaataacatgcACACCAAACAACTATCGGATGTAGATGATAAAAATGATGATTGTGAGGAATCTgcgaacaatttaataatagacATGACAGACGAAGACGAAGAACAAAACCATAGTTATACAGataaagaaaacaataaatcgaggccaataaaaaaatcgtttctggGAGAACCATCACCCGAAGATTATGTACTGATGAAAGAAGaaacttttaatttagaaCCAGTaaaaaatgGGCCAACAGGTGTTCTAGGcgattatttaatagaatataataattctaaaaagtTACCAAACGATGCGAGTAATGCAGACAAAGACATTGTTGACAATTTACGGATACGAAGAGAAGTTTTACCATCCATGTGggatgtatttgaaaaaaatattgaaaagctAAAACctggAGAATCATGTACAACATCAGTGACGCATAGACGTTATATTATCAACAAAGGAGCATTTCCTTGTTCACTGTGTGGCGAATGCTACGAGTTTGATCAAGGTGTTTGCCGTGACGAAGAAGAACCTCAGCCACCGGTCGAAGTTGATATCCAGcagcgtttatttatttgtcctACGTGTGGAAAATCTTTCCCTCGTCGTAGCTCATGGAAACGTCACCAAATGACTCACGAGGATGTGAAACCATTTGTCTGTCGCATATGTACGAGTGGCTTTAATCGTAAAGAACATTTGATGCGACACATGTTGTCGCATAGCACGATTAGACCATTTCCTTGTGAACGTTGTGGCAAACGGTTTATACGTAAAGAGCATTTGGCTAGACATCTTTTGTGTATACCGAGTTGTTCTAATTCGTCTGACATGCCGAGACCGTTCTGTTGTGATATTTGCAAACAAAGATTTGTGCGCAAAGAACATCTTTTCAGACATAGGAAACGTGCTCATGAACACGCATTAATAGTGGACAATCAGATTACAATGGAAGAAAAACCGTTTACTTGTTGGCAGTGCGGCAAGTGTTTCACTCGCTATGAACACCTGCGCAAACATTTGGATATCCACAACGGTATTATTCCTTCGTCTTCGACCGCACTACTTCCTGAAGTGACGCTATCGGAAATAACAGCCAAAGACTCTTCCATGGACATCAAAACGGAGAACTTGTCGGATTCTGAAGGTGAATCTGAAGTTCTTCCTCCAGTTAGTGTGCTGGAACTTAACGAACAACCGCCTGAACAAGGGAGACCTAAGCCGAGTACCCTTTGTACTATTTGTCAAAAGACATTTTCCCGTCGTAGCCACTTGCTGCGCCATTTGAAACGCATACACAAAGTAGAACCGGTGTTGACCAGAAGACGGGTGACTAAGTCTGGCGATGAAAATGGCAATTCTATTGAGGAAACTAAATGGGAATGTCATACATGTGGAAAGACATTTTCCAGGCAAGCTCATCTGGATCGGCACGAAAAGAACTTACATAGTGAAGAGCGTATGGTGCCCGCCCCTTACGAGTGCGTTTCTTGCGGTCAAGCATTCTTCGATAGCAATCTACTCAACCAACACATGGCAACCCATGGGAACACTGTGACTGACAATTTTGTTTGGATGTGA
Protein Sequence
MEYDEDDGPQEETTTTAAAAAVISSCCRLCCKPSTDVDGRHRIIVDNRDNNNDDDDDDDDGGGGGTRPDGRDLRGIIVKHLRIQVTEDDGLSKIICSECLGFLNEWSQFYEMCSKNNNMHTKQLSDVDDKNDDCEESANNLIIDMTDEDEEQNHSYTDKENNKSRPIKKSFLGEPSPEDYVLMKEETFNLEPVKNGPTGVLGDYLIEYNNSKKLPNDASNADKDIVDNLRIRREVLPSMWDVFEKNIEKLKPGESCTTSVTHRRYIINKGAFPCSLCGECYEFDQGVCRDEEEPQPPVEVDIQQRLFICPTCGKSFPRRSSWKRHQMTHEDVKPFVCRICTSGFNRKEHLMRHMLSHSTIRPFPCERCGKRFIRKEHLARHLLCIPSCSNSSDMPRPFCCDICKQRFVRKEHLFRHRKRAHEHALIVDNQITMEEKPFTCWQCGKCFTRYEHLRKHLDIHNGIIPSSSTALLPEVTLSEITAKDSSMDIKTENLSDSEGESEVLPPVSVLELNEQPPEQGRPKPSTLCTICQKTFSRRSHLLRHLKRIHKVEPVLTRRRVTKSGDENGNSIEETKWECHTCGKTFSRQAHLDRHEKNLHSEERMVPAPYECVSCGQAFFDSNLLNQHMATHGNTVTDNFVWM